NCI-H1792 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
Description disease: adenocarcinoma (lung primary) (Cell Line Ontology, CLO_0008019)
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Genes

238 genes with high or low expression in NCI-H1792 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
TARBP2 TAR (HIV-1) RNA binding protein 2 3.60177
DNAAF5 dynein, axonemal, assembly factor 5 3.49469
PCBP2 poly(rC) binding protein 2 3.33677
NEMF nuclear export mediator factor 3.13156
LRFN4 leucine rich repeat and fibronectin type III domain containing 4 3.12092
EIF3B eukaryotic translation initiation factor 3, subunit B 3.0852
ATP5G2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) 2.99973
PRR13 proline rich 13 2.96857
PRPS2 phosphoribosyl pyrophosphate synthetase 2 2.95895
GNA12 guanine nucleotide binding protein (G protein) alpha 12 2.78661
FTSJ2 FtsJ RNA methyltransferase homolog 2 (E. coli) 2.67371
IMPACT impact RWD domain protein 2.59586
NUBPL nucleotide binding protein-like 2.54257
VRK2 vaccinia related kinase 2 2.49788
PTCD3 pentatricopeptide repeat domain 3 2.48951
DCTN2 dynactin 2 (p50) 2.46522
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 2.29438
NPFF neuropeptide FF-amide peptide precursor 2.2702
TSFM Ts translation elongation factor, mitochondrial 2.24946
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma 2.23518
PVT1 Pvt1 oncogene (non-protein coding) 2.18539
MARS methionyl-tRNA synthetase 2.17374
ENOSF1 enolase superfamily member 1 2.16062
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 2.13701
SSRP1 structure specific recognition protein 1 2.09614
MAP3K12 mitogen-activated protein kinase kinase kinase 12 2.07855
METTL1 methyltransferase like 1 2.04562
USP34 ubiquitin specific peptidase 34 2.02187
METTL21B methyltransferase like 21B 1.98866
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.97478
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin 1.97247
NFS1 NFS1 cysteine desulfurase 1.94825
TTI1 TELO2 interacting protein 1 1.93549
CTDSP2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 1.92635
INTS1 integrator complex subunit 1 1.9254
SOS1 son of sevenless homolog 1 (Drosophila) 1.92195
IVD isovaleryl-CoA dehydrogenase 1.90121
TSPAN31 tetraspanin 31 1.89243
PTGIS prostaglandin I2 (prostacyclin) synthase 1.88477
CDK4 cyclin-dependent kinase 4 1.8747
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 1.85944
TMEM5 transmembrane protein 5 1.85092
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa 1.81696
PFDN4 prefoldin subunit 4 1.80718
DIAPH2-AS1 DIAPH2 antisense RNA 1 1.79749
FKBP3 FK506 binding protein 3, 25kDa 1.79632
SS18 synovial sarcoma translocation, chromosome 18 1.74764
UGDH UDP-glucose 6-dehydrogenase 1.74436
AIP aryl hydrocarbon receptor interacting protein 1.73801
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1 1.71665
MDH2 malate dehydrogenase 2, NAD (mitochondrial) 1.70654
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1 1.69728
TTLL5 tubulin tyrosine ligase-like family member 5 1.68527
CPNE7 copine VII 1.66622
STAC SH3 and cysteine rich domain 1.65832
SHROOM2 shroom family member 2 1.64872
XYLB xylulokinase homolog (H. influenzae) 1.64225
GPR143 G protein-coupled receptor 143 1.63357
COX11 COX11 cytochrome c oxidase copper chaperone 1.63355
KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast) 1.63181
EXOG endo/exonuclease (5'-3'), endonuclease G-like 1.60748
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 1.60107
CBX5 chromobox homolog 5 1.59906
PITRM1 pitrilysin metallopeptidase 1 1.59905
FAHD2A fumarylacetoacetate hydrolase domain containing 2A 1.59896
LEPR leptin receptor 1.58646
IPO4 importin 4 1.58337
DHODH dihydroorotate dehydrogenase (quinone) 1.56544
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 1.56222
SERTAD2 SERTA domain containing 2 1.56026
FANCL Fanconi anemia, complementation group L 1.5572
AP3S1 adaptor-related protein complex 3, sigma 1 subunit 1.55095
M6PR mannose-6-phosphate receptor (cation dependent) 1.54117
YBX3 Y box binding protein 3 1.53725
GORASP1 golgi reassembly stacking protein 1, 65kDa 1.5316
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 1.53052
TK2 thymidine kinase 2, mitochondrial 1.5292
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin 1.52631
TMEM106B transmembrane protein 106B 1.52253
CLCF1 cardiotrophin-like cytokine factor 1 1.52006
LAMA2 laminin, alpha 2 1.49963
KIAA0391 KIAA0391 1.49602
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 1.49535
STRA6 stimulated by retinoic acid 6 1.48822
IL13RA2 interleukin 13 receptor, alpha 2 1.48768
PAPOLA poly(A) polymerase alpha 1.47787
AADAC arylacetamide deacetylase 1.47239
ABCA6 ATP-binding cassette, sub-family A (ABC1), member 6 1.47135
CRISP2 cysteine-rich secretory protein 2 1.46571
MRPL12 mitochondrial ribosomal protein L12 1.46256
RARB retinoic acid receptor, beta 1.46152
LAMC3 laminin, gamma 3 1.45997
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1 1.45676
HMOX1 heme oxygenase 1 1.43268
SPTBN2 spectrin, beta, non-erythrocytic 2 1.41944

low expression

Symbol Name Standardized Value
BTG3 BTG family, member 3 -3.20114
HS6ST1 heparan sulfate 6-O-sulfotransferase 1 -2.73772
HSPA13 heat shock protein 70kDa family, member 13 -2.61381
GLI2 GLI family zinc finger 2 -2.5837
NOVA2 neuro-oncological ventral antigen 2 -2.56322
MSI1 musashi RNA-binding protein 1 -2.52838
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome -2.4973
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) -2.4386
KAT5 K(lysine) acetyltransferase 5 -2.43724
ACYP2 acylphosphatase 2, muscle type -2.43398
PSORS1C1 psoriasis susceptibility 1 candidate 1 -2.43213
NEU2 sialidase 2 (cytosolic sialidase) -2.30951
CRLF1 cytokine receptor-like factor 1 -2.2647
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 -2.2557
INSR insulin receptor -2.22488
JAG1 jagged 1 -2.20753
PRNP prion protein -2.18689
IL36G interleukin 36, gamma -2.10129
NDEL1 nudE neurodevelopment protein 1-like 1 -2.09411
TAS2R3 taste receptor, type 2, member 3 -2.08717
STK19 serine/threonine kinase 19 -2.08103
PER1 period circadian clock 1 -2.04167
MCF2 MCF.2 cell line derived transforming sequence -2.00827
OR12D3 olfactory receptor, family 12, subfamily D, member 3 -1.99882
TRAF3IP3 TRAF3 interacting protein 3 -1.99222
PROX1 prospero homeobox 1 -1.98529
SCGB2A1 secretoglobin, family 2A, member 1 -1.97814
CDC16 cell division cycle 16 -1.97251
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3 -1.96654
HIST1H3C histone cluster 1, H3c -1.95554
CBX2 chromobox homolog 2 -1.94234
NXF1 nuclear RNA export factor 1 -1.93227
GALNT4 polypeptide N-acetylgalactosaminyltransferase 4 -1.92754
WBP4 WW domain binding protein 4 -1.92711
BCAS1 breast carcinoma amplified sequence 1 -1.92439
YPEL1 yippee-like 1 (Drosophila) -1.92374
USP25 ubiquitin specific peptidase 25 -1.92342
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 -1.91115
XPO4 exportin 4 -1.91074
TSSK2 testis-specific serine kinase 2 -1.90008
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa -1.87844
SRPK3 SRSF protein kinase 3 -1.87612
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 -1.87405
HNRNPF heterogeneous nuclear ribonucleoprotein F -1.86349
LIPC lipase, hepatic -1.85675
GPR50 G protein-coupled receptor 50 -1.85053
ANP32C acidic (leucine-rich) nuclear phosphoprotein 32 family, member C -1.84508
PGAM2 phosphoglycerate mutase 2 (muscle) -1.84057
ZNF696 zinc finger protein 696 -1.83787
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) -1.80979
ERP29 endoplasmic reticulum protein 29 -1.8037
PDPK1 3-phosphoinositide dependent protein kinase 1 -1.79952
PHOX2A paired-like homeobox 2a -1.794
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae) -1.7906
NVL nuclear VCP-like -1.7857
KCNK13 potassium channel, two pore domain subfamily K, member 13 -1.78446
ERN1 endoplasmic reticulum to nucleus signaling 1 -1.7831
CPN1 carboxypeptidase N, polypeptide 1 -1.76552
FOXD3 forkhead box D3 -1.7598
CSF1R colony stimulating factor 1 receptor -1.74191
PGR progesterone receptor -1.73873
HOXD3 homeobox D3 -1.73272
ZC3H13 zinc finger CCCH-type containing 13 -1.72929
DPF3 D4, zinc and double PHD fingers, family 3 -1.72817
GNGT2 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2 -1.72605
PSME4 proteasome (prosome, macropain) activator subunit 4 -1.726
MAGEL2 melanoma antigen family L2 -1.71408
AKAP10 A kinase (PRKA) anchor protein 10 -1.70422
ING1 inhibitor of growth family, member 1 -1.69688
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 -1.69423
PSPN persephin -1.69123
GABARAP GABA(A) receptor-associated protein -1.69046
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 -1.6834
MGEA5 meningioma expressed antigen 5 (hyaluronidase) -1.68261
N4BP1 NEDD4 binding protein 1 -1.66162
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 -1.65986
BNC1 basonuclin 1 -1.65478
SAP18 Sin3A-associated protein, 18kDa -1.64937
C9 complement component 9 -1.64718
CDX1 caudal type homeobox 1 -1.64526
F2 coagulation factor II (thrombin) -1.63657
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 -1.6342
GNMT glycine N-methyltransferase -1.62983
NDE1 nudE neurodevelopment protein 1 -1.62423
ZNF442 zinc finger protein 442 -1.61281
FRS2 fibroblast growth factor receptor substrate 2 -1.60271
OSBP oxysterol binding protein -1.58136
DIAPH3 diaphanous-related formin 3 -1.56649
GCM2 glial cells missing homolog 2 (Drosophila) -1.5618
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 -1.56168
HABP2 hyaluronan binding protein 2 -1.56055
HCRTR1 hypocretin (orexin) receptor 1 -1.54181
ZNF451 zinc finger protein 451 -1.54026
TM4SF4 transmembrane 4 L six family member 4 -1.52749
SELL selectin L -1.5234
KRT34 keratin 34, type I -1.51897
BBC3 BCL2 binding component 3 -1.51722
RXFP3 relaxin/insulin-like family peptide receptor 3 -1.51675
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene -1.51529
LPL lipoprotein lipase -1.51391
SRR serine racemase -1.51343
FBXW4 F-box and WD repeat domain containing 4 -1.50927
FBXO24 F-box protein 24 -1.50525
MYOD1 myogenic differentiation 1 -1.50292
TLN2 talin 2 -1.50256
TMEM11 transmembrane protein 11 -1.49965
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa -1.49786
CABP1 calcium binding protein 1 -1.49691
HS3ST3B1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 -1.49591
ASCL2 achaete-scute family bHLH transcription factor 2 -1.48701
BPESC1 blepharophimosis, epicanthus inversus and ptosis, candidate 1 (non-protein coding) -1.48655
TLR5 toll-like receptor 5 -1.48392
PYGM phosphorylase, glycogen, muscle -1.47604
ZFPL1 zinc finger protein-like 1 -1.47371
RNF113A ring finger protein 113A -1.47327
NXF3 nuclear RNA export factor 3 -1.47302
FAM215A family with sequence similarity 215, member A (non-protein coding) -1.47299
ADGRL4 adhesion G protein-coupled receptor L4 -1.46967
SOX3 SRY (sex determining region Y)-box 3 -1.46548
SLC6A5 solute carrier family 6 (neurotransmitter transporter), member 5 -1.46527
HHLA2 HERV-H LTR-associating 2 -1.46512
TAS2R1 taste receptor, type 2, member 1 -1.46281
OVOL2 ovo-like zinc finger 2 -1.45572
HIST1H4H histone cluster 1, H4h -1.45412
PGM5 phosphoglucomutase 5 -1.45316
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2 -1.45303
ZNF654 zinc finger protein 654 -1.45258
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2 -1.45071
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18 -1.4462
HUS1 HUS1 checkpoint homolog (S. pombe) -1.44482
NXPE4 neurexophilin and PC-esterase domain family, member 4 -1.43356
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2 -1.43343
SNTG2 syntrophin, gamma 2 -1.43021
ECE2 endothelin converting enzyme 2 -1.42822
USPL1 ubiquitin specific peptidase like 1 -1.42567
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 -1.42524
RPGRIP1 retinitis pigmentosa GTPase regulator interacting protein 1 -1.42478
NCR1 natural cytotoxicity triggering receptor 1 -1.42385
NEUROD2 neuronal differentiation 2 -1.42333
CXCL9 chemokine (C-X-C motif) ligand 9 -1.42012
FSCN3 fascin actin-bundling protein 3, testicular -1.42011
ZBTB3 zinc finger and BTB domain containing 3 -1.41707
CHGB chromogranin B -1.41623