NCI-H1793 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
Description disease: adenocarcinoma; non-small cell lung cancer (Cell Line Ontology, CLO_0008020)
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Genes

256 genes with high or low expression in NCI-H1793 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 3.60177
MEGF9 multiple EGF-like-domains 9 3.52146
STARD7 StAR-related lipid transfer (START) domain containing 7 3.35438
GSR glutathione reductase 3.14305
CBR1 carbonyl reductase 1 3.06939
GLA galactosidase, alpha 2.68905
SFTPD surfactant protein D 2.66126
DOCK3 dedicator of cytokinesis 3 2.53047
NRG1 neuregulin 1 2.50863
CFLAR CASP8 and FADD-like apoptosis regulator 2.47987
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 2.42362
FMO5 flavin containing monooxygenase 5 2.32542
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 2.23449
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 2.22736
KLHL3 kelch-like family member 3 2.21067
EMC3 ER membrane protein complex subunit 3 2.17564
UGDH UDP-glucose 6-dehydrogenase 2.15361
GSTA4 glutathione S-transferase alpha 4 2.14346
ABHD4 abhydrolase domain containing 4 2.14238
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 2.13735
CBR3 carbonyl reductase 3 2.13394
GSTT1 glutathione S-transferase theta 1 2.11997
TNNC1 troponin C type 1 (slow) 2.10318
SPARCL1 SPARC-like 1 (hevin) 2.06284
DOK5 docking protein 5 2.05944
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic 2.04996
CDO1 cysteine dioxygenase type 1 2.04694
AQP4 aquaporin 4 2.04185
TXN thioredoxin 1.99845
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 1.97271
KIR2DS3 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 3 1.97067
LTB4R2 leukotriene B4 receptor 2 1.9704
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2 1.96358
RNF115 ring finger protein 115 1.94845
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 1.94816
KIAA0319 KIAA0319 1.94719
SUSD5 sushi domain containing 5 1.93739
MAOA monoamine oxidase A 1.92146
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F 1.91383
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35 1.90669
CES1 carboxylesterase 1 1.90394
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2 1.88958
GIGYF2 GRB10 interacting GYF protein 2 1.87775
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein 1.87009
WFDC8 WAP four-disulfide core domain 8 1.86629
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11 1.85861
GSTA1 glutathione S-transferase alpha 1 1.84871
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3 1.84568
DIRAS2 DIRAS family, GTP-binding RAS-like 2 1.84534
RFXANK regulatory factor X-associated ankyrin-containing protein 1.83106
FAM105A family with sequence similarity 105, member A 1.81439
NDRG4 NDRG family member 4 1.81186
TDP2 tyrosyl-DNA phosphodiesterase 2 1.79237
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal) 1.79153
HHIPL2 HHIP-like 2 1.78832
OSGIN1 oxidative stress induced growth inhibitor 1 1.78319
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2 1.77691
GCLM glutamate-cysteine ligase, modifier subunit 1.77278
PPAP2A phosphatidic acid phosphatase type 2A 1.76368
TMOD1 tropomodulin 1 1.739
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 1.72137
SFTPB surfactant protein B 1.71774
KRT4 keratin 4, type II 1.71405
TP53I3 tumor protein p53 inducible protein 3 1.7065
PRDX1 peroxiredoxin 1 1.70454
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.70054
NR0B1 nuclear receptor subfamily 0, group B, member 1 1.6973
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 1.69568
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 1.69454
ABHD17A abhydrolase domain containing 17A 1.69405
SPC25 SPC25, NDC80 kinetochore complex component 1.67837
ACOT13 acyl-CoA thioesterase 13 1.66803
SFRP4 secreted frizzled-related protein 4 1.66383
MERTK MER proto-oncogene, tyrosine kinase 1.65503
HMGB3 high mobility group box 3 1.64919
NT5C2 5'-nucleotidase, cytosolic II 1.64817
TMEM38B transmembrane protein 38B 1.64124
GCLC glutamate-cysteine ligase, catalytic subunit 1.63918
STOM stomatin 1.63767
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 1.62559
PF4V1 platelet factor 4 variant 1 1.62185
PDGFD platelet derived growth factor D 1.61999
BHMT2 betaine--homocysteine S-methyltransferase 2 1.61857
DCAF6 DDB1 and CUL4 associated factor 6 1.61769
PGD phosphogluconate dehydrogenase 1.61252
SFTPC surfactant protein C 1.60683
ADM2 adrenomedullin 2 1.6011
ANKRD1 ankyrin repeat domain 1 (cardiac muscle) 1.59171
NXT2 nuclear transport factor 2-like export factor 2 1.59056
PHKB phosphorylase kinase, beta 1.58761
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 1.5811
AGER advanced glycosylation end product-specific receptor 1.57998
COL4A4 collagen, type IV, alpha 4 1.57603
HRASLS HRAS-like suppressor 1.57116
EGLN2 egl-9 family hypoxia-inducible factor 2 1.56827
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4 1.56412
CLIC2 chloride intracellular channel 2 1.55945
LPGAT1 lysophosphatidylglycerol acyltransferase 1 1.55523
REEP5 receptor accessory protein 5 1.546
UGP2 UDP-glucose pyrophosphorylase 2 1.54555
PHYH phytanoyl-CoA 2-hydroxylase 1.52539
DEFA6 defensin, alpha 6, Paneth cell-specific 1.52358
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator 1.50745
SDPR serum deprivation response 1.50535
CLDN8 claudin 8 1.50206
DPY19L1 dpy-19-like 1 (C. elegans) 1.502
TLK1 tousled-like kinase 1 1.50199
EXOSC7 exosome component 7 1.49731
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 1.49413
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 1.49284
OLAH oleoyl-ACP hydrolase 1.48862
RALGAPB Ral GTPase activating protein, beta subunit (non-catalytic) 1.48811
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 1.48695
TMEM106C transmembrane protein 106C 1.48612
TAF9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa 1.48239
CASP6 caspase 6, apoptosis-related cysteine peptidase 1.47826
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow 1.47395
ABLIM1 actin binding LIM protein 1 1.4675
CBX2 chromobox homolog 2 1.46552
HMGB3P1 high mobility group box 3 pseudogene 1 1.46488
PHKA1 phosphorylase kinase, alpha 1 (muscle) 1.45971
CRTAC1 cartilage acidic protein 1 1.45822
HMOX1 heme oxygenase 1 1.4575
CHST10 carbohydrate sulfotransferase 10 1.45421
MPPED1 metallophosphoesterase domain containing 1 1.4515
SGCE sarcoglycan, epsilon 1.44792
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1 1.44789
ISCA1 iron-sulfur cluster assembly 1 1.44608
FASTKD2 FAST kinase domains 2 1.44181
FBLN5 fibulin 5 1.43996
RIT1 Ras-like without CAAX 1 1.43249
PCDHB13 protocadherin beta 13 1.4308
SERINC3 serine incorporator 3 1.42899
MCOLN3 mucolipin 3 1.42765
ZNF365 zinc finger protein 365 1.42571
LPCAT1 lysophosphatidylcholine acyltransferase 1 1.42472
PCDHA6 protocadherin alpha 6 1.42337
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 1.42307
NPR3 natriuretic peptide receptor 3 1.42114
TBK1 TANK-binding kinase 1 1.42053
ACTR10 actin-related protein 10 homolog (S. cerevisiae) 1.41956
NMBR neuromedin B receptor 1.41718

low expression

Symbol Name Standardized Value
GFER growth factor, augmenter of liver regeneration -3.53725
RFX5 regulatory factor X, 5 (influences HLA class II expression) -3.53718
PARP6 poly (ADP-ribose) polymerase family, member 6 -3.32151
IQSEC1 IQ motif and Sec7 domain 1 -3.16478
SP2 Sp2 transcription factor -3.0729
BTN2A1 butyrophilin, subfamily 2, member A1 -2.98636
WBP11 WW domain binding protein 11 -2.82832
FIP1L1 factor interacting with PAPOLA and CPSF1 -2.54198
GON4L gon-4-like (C. elegans) -2.50772
SERGEF secretion regulating guanine nucleotide exchange factor -2.43912
RNF126P1 ring finger protein 126 pseudogene 1 -2.35114
RS1 retinoschisin 1 -2.27138
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide -2.26345
TPP1 tripeptidyl peptidase I -2.25693
SAP130 Sin3A-associated protein, 130kDa -2.25174
XPO6 exportin 6 -2.20892
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 -2.1664
BTN3A1 butyrophilin, subfamily 3, member A1 -2.14541
ALK anaplastic lymphoma receptor tyrosine kinase -2.14366
ABT1 activator of basal transcription 1 -2.12997
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 -2.11022
CSNK2A1 casein kinase 2, alpha 1 polypeptide -2.10047
TDP1 tyrosyl-DNA phosphodiesterase 1 -2.09434
PTPRA protein tyrosine phosphatase, receptor type, A -2.0925
KIAA0430 KIAA0430 -2.05222
NARFL nuclear prelamin A recognition factor-like -2.03379
PDPK1 3-phosphoinositide dependent protein kinase 1 -1.96975
NME3 NME/NM23 nucleoside diphosphate kinase 3 -1.96838
ZKSCAN8 zinc finger with KRAB and SCAN domains 8 -1.96153
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3 -1.95168
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3 -1.94362
CARD9 caspase recruitment domain family, member 9 -1.89838
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1 -1.88233
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) -1.87091
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa -1.86562
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F -1.84877
ADAR adenosine deaminase, RNA-specific -1.8486
CCL27 chemokine (C-C motif) ligand 27 -1.84308
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 -1.83527
ZNF197 zinc finger protein 197 -1.81985
ARL17A ADP-ribosylation factor-like 17A -1.81875
MAK male germ cell-associated kinase -1.78867
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme -1.78717
ZC3H3 zinc finger CCCH-type containing 3 -1.77728
LAT linker for activation of T cells -1.77341
TLE3 transducin-like enhancer of split 3 -1.77047
CSHL1 chorionic somatomammotropin hormone-like 1 -1.76054
NRXN2 neurexin 2 -1.75272
SAP30BP SAP30 binding protein -1.74562
NXT1 nuclear transport factor 2-like export factor 1 -1.73948
NCOR2 nuclear receptor corepressor 2 -1.73619
C1QTNF1 C1q and tumor necrosis factor related protein 1 -1.72198
IL5RA interleukin 5 receptor, alpha -1.70454
TSC2 tuberous sclerosis 2 -1.69345
CANT1 calcium activated nucleotidase 1 -1.68717
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase) -1.68442
G0S2 G0/G1 switch 2 -1.665
NOMO2 NODAL modulator 2 -1.65979
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial -1.65295
GBP1 guanylate binding protein 1, interferon-inducible -1.64042
KRT20 keratin 20, type I -1.63668
PRKCSH protein kinase C substrate 80K-H -1.60557
KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast) -1.60169
BTN3A3 butyrophilin, subfamily 3, member A3 -1.60027
ZNF337 zinc finger protein 337 -1.58645
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 -1.58505
UTS2 urotensin 2 -1.58361
FUT2 fucosyltransferase 2 (secretor status included) -1.57746
MEA1 male-enhanced antigen 1 -1.57646
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 -1.57592
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae) -1.56979
CLEC16A C-type lectin domain family 16, member A -1.56877
FAM53B family with sequence similarity 53, member B -1.56599
HOXA10 homeobox A10 -1.56049
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) -1.55964
HIST1H3G histone cluster 1, H3g -1.55604
CSNK1E casein kinase 1, epsilon -1.54884
UQCRC2 ubiquinol-cytochrome c reductase core protein II -1.54713
HMGA1 high mobility group AT-hook 1 -1.54657
CCHCR1 coiled-coil alpha-helical rod protein 1 -1.54234
PISD phosphatidylserine decarboxylase -1.5385
DPH5 diphthamide biosynthesis 5 -1.53379
ALG12 ALG12, alpha-1,6-mannosyltransferase -1.52883
AEN apoptosis enhancing nuclease -1.52605
TLK2 tousled-like kinase 2 -1.51953
MTOR mechanistic target of rapamycin (serine/threonine kinase) -1.51261
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic) -1.51121
PXDN peroxidasin -1.50803
PMEL premelanosome protein -1.49956
PIGO phosphatidylinositol glycan anchor biosynthesis, class O -1.49914
CSNK1G2 casein kinase 1, gamma 2 -1.49842
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B -1.4918
MEG3 maternally expressed 3 (non-protein coding) -1.49005
RPL10A ribosomal protein L10a -1.48656
FKBP4 FK506 binding protein 4, 59kDa -1.48166
MIA2 melanoma inhibitory activity 2 -1.47852
SPEN spen family transcriptional repressor -1.47558
BRAF B-Raf proto-oncogene, serine/threonine kinase -1.47304
FBXL14 F-box and leucine-rich repeat protein 14 -1.46765
ZNF384 zinc finger protein 384 -1.4565
MRPS18B mitochondrial ribosomal protein S18B -1.4552
PTGDS prostaglandin D2 synthase 21kDa (brain) -1.45444
SH3GL3 SH3-domain GRB2-like 3 -1.45141
MED13L mediator complex subunit 13-like -1.44516
CDC5L cell division cycle 5-like -1.43886
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae) -1.43321
NSFL1C NSFL1 (p97) cofactor (p47) -1.42919
IMP4 IMP4, U3 small nucleolar ribonucleoprotein -1.42761
TASP1 taspase, threonine aspartase, 1 -1.42523
PER2 period circadian clock 2 -1.42391
CEP63 centrosomal protein 63kDa -1.42217
RPL37A ribosomal protein L37a -1.42189
UBFD1 ubiquitin family domain containing 1 -1.42046
UBE2I ubiquitin-conjugating enzyme E2I -1.41943