NCI-H2087 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
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Genes

284 genes with high or low expression in NCI-H2087 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
PARD3 par-3 family cell polarity regulator 3.59669
DAZAP2 DAZ associated protein 2 3.57691
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein 3.2629
EIF4B eukaryotic translation initiation factor 4B 2.81096
GOLGA3 golgin A3 2.66812
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 2.6218
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 2.57002
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 2.53991
IK IK cytokine, down-regulator of HLA II 2.45607
SCFD1 sec1 family domain containing 1 2.42829
SRPR signal recognition particle receptor (docking protein) 2.40784
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial 2.31279
SPTB spectrin, beta, erythrocytic 2.30617
CLIP4 CAP-GLY domain containing linker protein family, member 4 2.30575
CTDSP2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 2.30329
SRP54 signal recognition particle 54kDa 2.28703
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2 2.27804
ACP6 acid phosphatase 6, lysophosphatidic 2.27726
CCNH cyclin H 2.26248
ANKHD1 ankyrin repeat and KH domain containing 1 2.21748
METTL21B methyltransferase like 21B 2.18906
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8 2.18255
TSFM Ts translation elongation factor, mitochondrial 2.15765
WDR55 WD repeat domain 55 2.15479
USP39 ubiquitin specific peptidase 39 2.14979
ATXN2 ataxin 2 2.12186
CASP4 caspase 4, apoptosis-related cysteine peptidase 2.10525
SCEL sciellin 2.09855
SMYD5 SMYD family member 5 2.06544
TEP1 telomerase-associated protein 1 2.06021
CUL2 cullin 2 2.05354
TSPAN31 tetraspanin 31 2.04052
MBIP MAP3K12 binding inhibitory protein 1 2.00535
NSA2 NSA2 ribosome biogenesis homolog (S. cerevisiae) 1.99719
GFPT1 glutamine--fructose-6-phosphate transaminase 1 1.97809
TSPAN3 tetraspanin 3 1.96433
TMEM70 transmembrane protein 70 1.95772
BPIFA1 BPI fold containing family A, member 1 1.94106
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 1.94008
WDR37 WD repeat domain 37 1.93905
COG2 component of oligomeric golgi complex 2 1.92943
NOL6 nucleolar protein 6 (RNA-associated) 1.92608
RHD Rh blood group, D antigen 1.91497
PSME4 proteasome (prosome, macropain) activator subunit 4 1.90698
OR10H1 olfactory receptor, family 10, subfamily H, member 1 1.89394
METTL1 methyltransferase like 1 1.87295
CDK4 cyclin-dependent kinase 4 1.86235
HTRA2 HtrA serine peptidase 2 1.84576
ADGRF5 adhesion G protein-coupled receptor F5 1.82915
HMGB3P1 high mobility group box 3 pseudogene 1 1.81951
ASPH aspartate beta-hydroxylase 1.8187
RGS17 regulator of G-protein signaling 17 1.80633
PELO pelota homolog (Drosophila) 1.80532
BRDT bromodomain, testis-specific 1.8029
CAST calpastatin 1.79292
AKAP6 A kinase (PRKA) anchor protein 6 1.79288
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin 1.79148
ARHGAP5 Rho GTPase activating protein 5 1.77472
GTF2B general transcription factor IIB 1.77226
AVIL advillin 1.76782
MPHOSPH10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) 1.7568
IMMT inner membrane protein, mitochondrial 1.75153
SNRNP27 small nuclear ribonucleoprotein 27kDa (U4/U6.U5) 1.74874
CCT4 chaperonin containing TCP1, subunit 4 (delta) 1.74867
SEC24A SEC24 family member A 1.74593
SH3YL1 SH3 and SYLF domain containing 1 1.74389
THUMPD2 THUMP domain containing 2 1.73843
DUSP5 dual specificity phosphatase 5 1.72839
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 1.71912
MSTO1 misato 1, mitochondrial distribution and morphology regulator 1.71239
RHCE Rh blood group, CcEe antigens 1.69996
PELI1 pellino E3 ubiquitin protein ligase 1 1.69349
DGUOK deoxyguanosine kinase 1.68307
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 1.68219
PAEP progestagen-associated endometrial protein 1.66727
MYO6 myosin VI 1.65746
PADI1 peptidyl arginine deiminase, type I 1.65645
INO80B INO80 complex subunit B 1.64731
FMO5 flavin containing monooxygenase 5 1.64222
AARS alanyl-tRNA synthetase 1.63215
FNDC4 fibronectin type III domain containing 4 1.62574
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit 1.62421
UBAP1 ubiquitin associated protein 1 1.62048
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 1.61233
TOP1 topoisomerase (DNA) I 1.61016
TMC5 transmembrane channel-like 5 1.60956
ABI1 abl-interactor 1 1.60562
HIST1H4L histone cluster 1, H4l 1.60535
GTPBP4 GTP binding protein 4 1.60137
KDR kinase insert domain receptor 1.59777
PREB prolactin regulatory element binding 1.59752
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 1.59592
REN renin 1.59545
SRPX2 sushi-repeat containing protein, X-linked 2 1.59206
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6 1.58996
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 1.58651
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1 1.58519
UBA3 ubiquitin-like modifier activating enzyme 3 1.58344
ARCN1 archain 1 1.58074
CTSC cathepsin C 1.55589
CGREF1 cell growth regulator with EF-hand domain 1 1.55512
CSNK1A1 casein kinase 1, alpha 1 1.55277
TTC27 tetratricopeptide repeat domain 27 1.55088
GRAMD1C GRAM domain containing 1C 1.54604
CLDN10 claudin 10 1.54268
GLS2 glutaminase 2 (liver, mitochondrial) 1.53898
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme 1.53746
MERTK MER proto-oncogene, tyrosine kinase 1.53549
BCAS2 breast carcinoma amplified sequence 2 1.53389
LPIN2 lipin 2 1.53183
ENDOD1 endonuclease domain containing 1 1.52558
ELL2 elongation factor, RNA polymerase II, 2 1.52197
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B 1.51094
COPG1 coatomer protein complex, subunit gamma 1 1.50636
GCKR glucokinase (hexokinase 4) regulator 1.49533
KIAA0391 KIAA0391 1.4866
KHNYN KH and NYN domain containing 1.48314
ZNF654 zinc finger protein 654 1.47523
GADD45A growth arrest and DNA-damage-inducible, alpha 1.4737
ALCAM activated leukocyte cell adhesion molecule 1.46484
CCDC14 coiled-coil domain containing 14 1.45989
COPB2 coatomer protein complex, subunit beta 2 (beta prime) 1.45623
DCAF13 DDB1 and CUL4 associated factor 13 1.44866
RBM39 RNA binding motif protein 39 1.44559
SLCO4C1 solute carrier organic anion transporter family, member 4C1 1.44474
YIPF5 Yip1 domain family, member 5 1.44415
ACIN1 apoptotic chromatin condensation inducer 1 1.44033
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4 1.4374
ADM2 adrenomedullin 2 1.43074
SRSF8 serine/arginine-rich splicing factor 8 1.4306
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae) 1.42975
KDM4D lysine (K)-specific demethylase 4D 1.42957
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 1.42664
IL36R interleukin 36 receptor 1.42078
ITCH itchy E3 ubiquitin protein ligase 1.41979
ACAD8 acyl-CoA dehydrogenase family, member 8 1.41896
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 1.41827

low expression

Symbol Name Standardized Value
RAB9A RAB9A, member RAS oncogene family -3.53725
TRAPPC2 trafficking protein particle complex 2 -3.47489
TMEM50A transmembrane protein 50A -2.94648
ADCK4 aarF domain containing kinase 4 -2.9113
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa -2.68812
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -2.55896
PRMT1 protein arginine methyltransferase 1 -2.45969
CPA4 carboxypeptidase A4 -2.44801
TMA7 translation machinery associated 7 homolog (S. cerevisiae) -2.42645
MS4A5 membrane-spanning 4-domains, subfamily A, member 5 -2.42173
NELL2 NEL-like 2 (chicken) -2.39342
WTAP Wilms tumor 1 associated protein -2.36716
CDC27 cell division cycle 27 -2.36684
PRPF4B pre-mRNA processing factor 4B -2.35207
TRPV4 transient receptor potential cation channel, subfamily V, member 4 -2.34703
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha -2.32937
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 -2.27381
PTCH2 patched 2 -2.20075
TSPY1 testis specific protein, Y-linked 1 -2.18787
CCL19 chemokine (C-C motif) ligand 19 -2.18178
HIST1H2BO histone cluster 1, H2bo -2.15951
DBF4B DBF4 zinc finger B -2.11644
KCTD9 potassium channel tetramerization domain containing 9 -2.10604
SPATA1 spermatogenesis associated 1 -2.10302
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1 -2.08319
EIF1AX eukaryotic translation initiation factor 1A, X-linked -2.08014
TMEM47 transmembrane protein 47 -2.07985
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 -2.03523
DNM2 dynamin 2 -2.02534
SMAD2 SMAD family member 2 -2.00408
KRT14 keratin 14, type I -2.00081
RHAG Rh-associated glycoprotein -1.98674
TXNL4A thioredoxin-like 4A -1.96012
NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa -1.93302
ERF Ets2 repressor factor -1.92978
SYP synaptophysin -1.92972
ARL3 ADP-ribosylation factor-like 3 -1.91792
ERMAP erythroblast membrane-associated protein (Scianna blood group) -1.91555
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe) -1.90645
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase -1.90086
LRRTM2 leucine rich repeat transmembrane neuronal 2 -1.89548
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1 -1.87016
NFIX nuclear factor I/X (CCAAT-binding transcription factor) -1.86345
TXNL1 thioredoxin-like 1 -1.85139
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit -1.83507
ART1 ADP-ribosyltransferase 1 -1.83123
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled -1.82635
SCN11A sodium channel, voltage gated, type XI alpha subunit -1.82593
UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI -1.82275
MTCP1 mature T-cell proliferation 1 -1.81526
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase -1.81484
ATP5E ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit -1.8144
DENND1A DENN/MADD domain containing 1A -1.80923
EPHA3 EPH receptor A3 -1.80342
NUP62 nucleoporin 62kDa -1.79197
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter) -1.76539
SSX2 synovial sarcoma, X breakpoint 2 -1.7557
ZCCHC2 zinc finger, CCHC domain containing 2 -1.75426
SP2 Sp2 transcription factor -1.74512
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -1.73151
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 -1.72274
ULK2 unc-51 like autophagy activating kinase 2 -1.72254
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 -1.71737
GRHPR glyoxylate reductase/hydroxypyruvate reductase -1.70225
CD96 CD96 molecule -1.70213
PHF14 PHD finger protein 14 -1.69821
DPYSL4 dihydropyrimidinase-like 4 -1.69807
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide -1.69779
COL9A1 collagen, type IX, alpha 1 -1.69686
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 -1.69292
FGF2 fibroblast growth factor 2 (basic) -1.69205
LILRP2 leukocyte immunoglobulin-like receptor pseudogene 2 -1.68463
CHMP7 charged multivesicular body protein 7 -1.67685
ZNF286A zinc finger protein 286A -1.6766
PTGES2 prostaglandin E synthase 2 -1.67557
RPS19 ribosomal protein S19 -1.67011
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 -1.663
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) -1.66052
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase -1.65723
ICOS inducible T-cell co-stimulator -1.64383
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2 -1.62689
KEAP1 kelch-like ECH-associated protein 1 -1.62416
PRDM5 PR domain containing 5 -1.61292
IL21R interleukin 21 receptor -1.60426
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) -1.60293
VDAC3 voltage-dependent anion channel 3 -1.60032
HOXD4 homeobox D4 -1.5933
HNRNPR heterogeneous nuclear ribonucleoprotein R -1.59081
TRPC4 transient receptor potential cation channel, subfamily C, member 4 -1.58868
RFPL1 ret finger protein-like 1 -1.58801
CARM1 coactivator-associated arginine methyltransferase 1 -1.58583
ISCA1 iron-sulfur cluster assembly 1 -1.58248
DGCR14 DiGeorge syndrome critical region gene 14 -1.57845
UROS uroporphyrinogen III synthase -1.57599
CLDN14 claudin 14 -1.57117
NEK1 NIMA-related kinase 1 -1.56461
ERCC1 excision repair cross-complementation group 1 -1.55877
IL2RA interleukin 2 receptor, alpha -1.54734
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 -1.54097
CNOT7 CCR4-NOT transcription complex, subunit 7 -1.54092
TNNI1 troponin I type 1 (skeletal, slow) -1.5373
UBE2A ubiquitin-conjugating enzyme E2A -1.53728
HDDC2 HD domain containing 2 -1.53333
NOX5 NADPH oxidase, EF-hand calcium binding domain 5 -1.52924
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -1.52559
RAB8A RAB8A, member RAS oncogene family -1.52489
MARK4 MAP/microtubule affinity-regulating kinase 4 -1.52203
DSPP dentin sialophosphoprotein -1.51544
ASTN1 astrotactin 1 -1.50925
RFX2 regulatory factor X, 2 (influences HLA class II expression) -1.50377
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon -1.5012
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene -1.50102
NCOA6 nuclear receptor coactivator 6 -1.49841
CD5 CD5 molecule -1.49831
APOBR apolipoprotein B receptor -1.49171
SMC1A structural maintenance of chromosomes 1A -1.49021
WNT6 wingless-type MMTV integration site family, member 6 -1.48837
NDUFA6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa -1.48497
XPA xeroderma pigmentosum, complementation group A -1.48391
MAP3K15 mitogen-activated protein kinase kinase kinase 15 -1.47974
FN3KRP fructosamine 3 kinase related protein -1.47419
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle -1.47357
HMHB1 histocompatibility (minor) HB-1 -1.47117
CD1C CD1c molecule -1.46951
ICAM5 intercellular adhesion molecule 5, telencephalin -1.46771
AMELX amelogenin, X-linked -1.4673
PDE7B phosphodiesterase 7B -1.46575
TBCB tubulin folding cofactor B -1.46329
ZBED1 zinc finger, BED-type containing 1 -1.46207
ZPBP zona pellucida binding protein -1.46006
ZNF428 zinc finger protein 428 -1.45811
ZBTB5 zinc finger and BTB domain containing 5 -1.45715
CALML5 calmodulin-like 5 -1.45195
MYH7 myosin, heavy chain 7, cardiac muscle, beta -1.45048
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) -1.44645
TM7SF3 transmembrane 7 superfamily member 3 -1.44478
PIK3C2G phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma -1.43854
APC2 adenomatosis polyposis coli 2 -1.43826
SLA Src-like-adaptor -1.437
PDE1B phosphodiesterase 1B, calmodulin-dependent -1.43167
COL1A2 collagen, type I, alpha 2 -1.42909
CA4 carbonic anhydrase IV -1.42721
TBX10 T-box 10 -1.42698
LAIR2 leukocyte-associated immunoglobulin-like receptor 2 -1.42617
ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9) -1.42116
MBNL3 muscleblind-like splicing regulator 3 -1.41802
OPRM1 opioid receptor, mu 1 -1.41602