NCI-H2141 Gene Set

Dataset Sanger Dependency Map Cancer Cell Line Proteomics
Category proteomics
Type cell line
Description cell line derived from Small Cell Lung Carcinoma Metastasis (Cell Model Passports, SIDM00699)
External Link https://cellmodelpassports.sanger.ac.uk/passports/SIDM00699
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Genes

199 proteins associated with the cell line NCI-H2141 from the Sanger Dependency Map Cancer Cell Line Proteomics dataset.

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ACTL6A actin-like 6A
ACTR1B ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
ACYP1 acylphosphatase 1, erythrocyte (common) type
ALDH9A1 aldehyde dehydrogenase 9 family, member A1
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
BUD31 BUD31 homolog (S. cerevisiae)
C11ORF54 chromosome 11 open reading frame 54
CALB2 calbindin 2
CAND1 cullin-associated and neddylation-dissociated 1
CBX1 chromobox homolog 1
CDYL chromodomain protein, Y-like
CELF1 CUGBP, Elav-like family member 1
CHAMP1 chromosome alignment maintaining phosphoprotein 1
CHD4 chromodomain helicase DNA binding protein 4
CHMP1B charged multivesicular body protein 1B
CIRBP cold inducible RNA binding protein
CKAP2 cytoskeleton associated protein 2
CKB creatine kinase, brain
CLDN12 claudin 12
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
DDB1 damage-specific DNA binding protein 1, 127kDa
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
DEK DEK proto-oncogene
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease
DLG3 discs, large homolog 3 (Drosophila)
ENO2 enolase 2 (gamma, neuronal)
FAM76B family with sequence similarity 76, member B
GDI1 GDP dissociation inhibitor 1
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
GTF2A2 general transcription factor IIA, 2, 12kDa
HCFC1 host cell factor C1
HDAC2 histone deacetylase 2
HDHD2 haloacid dehalogenase-like hydrolase domain containing 2
HMGB3 high mobility group box 3
HMGN2 high mobility group nucleosomal binding domain 2
HTATSF1 HIV-1 Tat specific factor 1
KAT7 K(lysine) acetyltransferase 7
KDM1A lysine (K)-specific demethylase 1A
LIG3 ligase III, DNA, ATP-dependent
MEAF6 MYST/Esa1-associated factor 6
MSH2 mutS homolog 2
MSH6 mutS homolog 6
MTA1 metastasis associated 1
NRF1 nuclear respiratory factor 1
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21
OR4K3 olfactory receptor, family 4, subfamily K, member 3 (gene/pseudogene)
PABPC3 poly(A) binding protein, cytoplasmic 3
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form)
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
PDS5B PDS5 cohesin associated factor B
PEX6 peroxisomal biogenesis factor 6
PHIP pleckstrin homology domain interacting protein
POGZ pogo transposable element with ZNF domain
PPME1 protein phosphatase methylesterase 1
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
PSIP1 PC4 and SFRS1 interacting protein 1
PTBP1 polypyrimidine tract binding protein 1
PTMS parathymosin
RAD21 RAD21 homolog (S. pombe)
RBM4B RNA binding motif protein 4B
RCC2 regulator of chromosome condensation 2
RING1 ring finger protein 1
RPRD1A regulation of nuclear pre-mRNA domain containing 1A
RSF1 remodeling and spacing factor 1
RTN3 reticulon 3
SAMD1 sterile alpha motif domain containing 1
SCAF4 SR-related CTD-associated factor 4
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
SMC1A structural maintenance of chromosomes 1A
SMC3 structural maintenance of chromosomes 3
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1
SMS spermine synthase
SOGA1 suppressor of glucose, autophagy associated 1
SPIN1 spindlin 1
SRSF4 serine/arginine-rich splicing factor 4
SRSF5 serine/arginine-rich splicing factor 5
SSRP1 structure specific recognition protein 1
STAG2 stromal antigen 2
STK24 serine/threonine kinase 24
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae)
SYNE2 spectrin repeat containing, nuclear envelope 2
TAGLN3 transgelin 3
TARDBP TAR DNA binding protein
THYN1 thymocyte nuclear protein 1
TMX4 thioredoxin-related transmembrane protein 4
TUBB2B tubulin, beta 2B class IIb
TUBB4A tubulin, beta 4A class IVa
UBL5 ubiquitin-like 5
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative)
USP11 ubiquitin specific peptidase 11
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae)
WBP11 WW domain binding protein 11
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
YLPM1 YLP motif containing 1
ZMYM3 zinc finger, MYM-type 3

Symbol Name
ACYP2 acylphosphatase 2, muscle type
AHNAK AHNAK nucleoprotein
ANXA11 annexin A11
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa
ASMTL acetylserotonin O-methyltransferase-like
BAG2 BCL2-associated athanogene 2
BICD2 bicaudal D homolog 2 (Drosophila)
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
CAST calpastatin
CAT catalase
CHID1 chitinase domain containing 1
CNN2 calponin 2
COA6 cytochrome c oxidase assembly factor 6
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1
CPOX coproporphyrinogen oxidase
CTSC cathepsin C
DCAF13 DDB1 and CUL4 associated factor 13
DDX19A DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DHODH dihydroorotate dehydrogenase (quinone)
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
DNPEP aspartyl aminopeptidase
DOCK10 dedicator of cytokinesis 10
DSG2 desmoglein 2
EHD2 EH-domain containing 2
ENG endoglin
ERI1 exoribonuclease 1
ERP44 endoplasmic reticulum protein 44
ETFA electron-transfer-flavoprotein, alpha polypeptide
ETFB electron-transfer-flavoprotein, beta polypeptide
FAHD2A fumarylacetoacetate hydrolase domain containing 2A
FNDC3B fibronectin type III domain containing 3B
FZD6 frizzled class receptor 6
GLUD1 glutamate dehydrogenase 1
GNG12 guanine nucleotide binding protein (G protein), gamma 12
GNG5 guanine nucleotide binding protein (G protein), gamma 5
GPATCH4 G patch domain containing 4
GRB7 growth factor receptor-bound protein 7
GRPEL1 GrpE-like 1, mitochondrial (E. coli)
GSTK1 glutathione S-transferase kappa 1
GTPBP4 GTP binding protein 4
HACL1 2-hydroxyacyl-CoA lyase 1
HMOX2 heme oxygenase 2
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
ITGAV integrin, alpha V
KATNA1 katanin p60 (ATPase containing) subunit A 1
LOC105376171 uncharacterized LOC105376171
MALSU1 mitochondrial assembly of ribosomal large subunit 1
MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta)
MRPS14 mitochondrial ribosomal protein S14
MRPS15 mitochondrial ribosomal protein S15
MRPS16 mitochondrial ribosomal protein S16
MRPS18B mitochondrial ribosomal protein S18B
MRPS26 mitochondrial ribosomal protein S26
MRPS6 mitochondrial ribosomal protein S6
MT-ATP8 ATP synthase F0 subunit 8
MYBBP1A MYB binding protein (P160) 1a
MYO1E myosin IE
N4BP1 NEDD4 binding protein 1
NDUFAF2 NADH dehydrogenase (ubiquinone) complex I, assembly factor 2
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NOC4L nucleolar complex associated 4 homolog (S. cerevisiae)
NOP14 NOP14 nucleolar protein
NOP16 NOP16 nucleolar protein
PAGR1 PAXIP1 associated glutamate-rich protein 1
PDE3A phosphodiesterase 3A, cGMP-inhibited
PEX3 peroxisomal biogenesis factor 3
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLSCR1 phospholipid scramblase 1
PXN paxillin
REXO2 RNA exonuclease 2
RPS27L ribosomal protein S27-like
RRAS related RAS viral (r-ras) oncogene homolog
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
S100A11 S100 calcium binding protein A11
SDAD1 SDA1 domain containing 1
SIRT5 sirtuin 5
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5
SLC35B2 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2
SMYD5 SMYD family member 5
SORBS3 sorbin and SH3 domain containing 3
STK10 serine/threonine kinase 10
STX8 syntaxin 8
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit
SUPT20HL1 suppressor of Ty 20 homolog (S. cerevisiae)-like 1
TBL3 transducin (beta)-like 3
TMF1 TATA element modulatory factor 1
TMOD3 tropomodulin 3 (ubiquitous)
TNS3 tensin 3
TPBG trophoblast glycoprotein
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
UBE2G2 ubiquitin-conjugating enzyme E2G 2
VDAC1 voltage-dependent anion channel 1
WSCD1 WSC domain containing 1
WWP2 WW domain containing E3 ubiquitin protein ligase 2
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZNF217 zinc finger protein 217