NCI-H2171 Gene Set

Dataset Sanger Dependency Map Cancer Cell Line Proteomics
Category proteomics
Type cell line
Description cell line derived from Small Cell Lung Carcinoma Metastasis (Cell Model Passports, SIDM00733)
External Link https://cellmodelpassports.sanger.ac.uk/passports/SIDM00733
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Genes

197 proteins associated with the cell line NCI-H2171 from the Sanger Dependency Map Cancer Cell Line Proteomics dataset.

Symbol Name
ACYP1 acylphosphatase 1, erythrocyte (common) type
ADNP activity-dependent neuroprotector homeobox
ARG2 arginase 2
ARHGAP30 Rho GTPase activating protein 30
BCL7A B-cell CLL/lymphoma 7A
BLM Bloom syndrome, RecQ helicase-like
BRD2 bromodomain containing 2
C12ORF57 chromosome 12 open reading frame 57
CBX5 chromobox homolog 5
CD109 CD109 molecule
CELF1 CUGBP, Elav-like family member 1
CFAP47 cilia and flagella associated protein 47
CHAF1A chromatin assembly factor 1, subunit A (p150)
CHAF1B chromatin assembly factor 1, subunit B (p60)
CHD4 chromodomain helicase DNA binding protein 4
CHD5 chromodomain helicase DNA binding protein 5
CHD8 chromodomain helicase DNA binding protein 8
CPSF2 cleavage and polyadenylation specific factor 2, 100kDa
CRNKL1 crooked neck pre-mRNA splicing factor 1
CTNNBL1 catenin, beta like 1
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DDX23 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
EED embryonic ectoderm development
EFTUD2 elongation factor Tu GTP binding domain containing 2
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EHMT2 euchromatic histone-lysine N-methyltransferase 2
EMG1 EMG1 N1-specific pseudouridine methyltransferase
ENO2 enolase 2 (gamma, neuronal)
FABP5P11 fatty acid binding protein 5 pseudogene 11
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
GPSM1 G-protein signaling modulator 1
GPSM2 G-protein signaling modulator 2
GTF2A2 general transcription factor IIA, 2, 12kDa
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa
HDAC2 histone deacetylase 2
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
ISY1 ISY1 splicing factor homolog (S. cerevisiae)
KDM1A lysine (K)-specific demethylase 1A
LOC102723897 WAS protein family homolog 2-like
MBTD1 mbt domain containing 1
METTL3 methyltransferase like 3
MLF2 myeloid leukemia factor 2
MORC2 MORC family CW-type zinc finger 2
MTA1 metastasis associated 1
NCOA5 nuclear receptor coactivator 5
NECAP1 NECAP endocytosis associated 1
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae)
PEX5 peroxisomal biogenesis factor 5
PLS3 plastin 3
POLDIP3 polymerase (DNA-directed), delta interacting protein 3
PPIG peptidylprolyl isomerase G (cyclophilin G)
PRPF19 pre-mRNA processing factor 19
PRPF38A pre-mRNA processing factor 38A
PRPF6 pre-mRNA processing factor 6
PRTFDC1 phosphoribosyl transferase domain containing 1
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
PTMS parathymosin
RAB2B RAB2B, member RAS oncogene family
RBM10 RNA binding motif protein 10
RBM39 RNA binding motif protein 39
RECQL RecQ helicase-like
RING1 ring finger protein 1
RNA5SP422 RNA, 5S ribosomal pseudogene 422
RPRD1B regulation of nuclear pre-mRNA domain containing 1B
SAP30 Sin3A-associated protein, 30kDa
SART1 squamous cell carcinoma antigen recognized by T cells
SF3A2 splicing factor 3a, subunit 2, 66kDa
SF3A3 splicing factor 3a, subunit 3, 60kDa
SF3B1 splicing factor 3b, subunit 1, 155kDa
SF3B2 splicing factor 3b, subunit 2, 145kDa
SF3B6 splicing factor 3b, subunit 6, 14kDa
SIN3A SIN3 transcription regulator family member A
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
SMC6 structural maintenance of chromosomes 6
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SRSF1 serine/arginine-rich splicing factor 1
SRSF3 serine/arginine-rich splicing factor 3
SSRP1 structure specific recognition protein 1
STAT2 signal transducer and activator of transcription 2, 113kDa
STXBP1 syntaxin binding protein 1
SUDS3 suppressor of defective silencing 3 homolog (S. cerevisiae)
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae)
SVIP small VCP/p97-interacting protein
TARDBP TAR DNA binding protein
TCF20 transcription factor 20 (AR1)
TIA1 TIA1 cytotoxic granule-associated RNA binding protein
TOX4 TOX high mobility group box family member 4
TPI1 triosephosphate isomerase 1
TUBB2B tubulin, beta 2B class IIb
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WDR5 WD repeat domain 5
WIZ widely interspaced zinc finger motifs
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3
ZGPAT zinc finger, CCCH-type with G patch domain
ZNF219 zinc finger protein 219
ZNF326 zinc finger protein 326
ZNF384 zinc finger protein 384
ZNF462 zinc finger protein 462

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACTA1 actin, alpha 1, skeletal muscle
AGFG1 ArfGAP with FG repeats 1
ALG5 ALG5, dolichyl-phosphate beta-glucosyltransferase
ANXA10 annexin A10
APOA1 apolipoprotein A-I
ATL3 atlastin GTPase 3
ATP5IF1 ATP synthase inhibitory factor subunit 1
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2
C11ORF58 chromosome 11 open reading frame 58
C5ORF15 chromosome 5 open reading frame 15
CAMK4 calcium/calmodulin-dependent protein kinase IV
CANX calnexin
CAST calpastatin
CD44 CD44 molecule (Indian blood group)
CDH26 cadherin 26
COG7 component of oligomeric golgi complex 7
CTSC cathepsin C
CXCR4 chemokine (C-X-C motif) receptor 4
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial
DHRS13 dehydrogenase/reductase (SDR family) member 13
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DUSP12 dual specificity phosphatase 12
EI24 etoposide induced 2.4
ERGIC1 endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
ERGIC3 ERGIC and golgi 3
ETHE1 ethylmalonic encephalopathy 1
FADD Fas (TNFRSF6)-associated via death domain
FAM174A family with sequence similarity 174, member A
FAM184B family with sequence similarity 184, member B
FHOD1 formin homology 2 domain containing 1
FTH1 ferritin, heavy polypeptide 1
GHITM growth hormone inducible transmembrane protein
GLUL glutamate-ammonia ligase
GM2A GM2 ganglioside activator
GNB4 guanine nucleotide binding protein (G protein), beta polypeptide 4
GYG1 glycogenin 1
HMGN5 high mobility group nucleosome binding domain 5
HOOK3 hook microtubule-tethering protein 3
IER3IP1 immediate early response 3 interacting protein 1
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KIAA1217 KIAA1217
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
LAT2 linker for activation of T cells family, member 2
LOC105369582 uncharacterized LOC105369582
LOC105373020 uncharacterized LOC105373020
LPP LIM domain containing preferred translocation partner in lipoma
M6PR mannose-6-phosphate receptor (cation dependent)
MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta)
MED11 mediator complex subunit 11
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
MRPL52 mitochondrial ribosomal protein L52
MRRF mitochondrial ribosome recycling factor
MTDH metadherin
MTERF3 mitochondrial transcription termination factor 3
MUC1 mucin 1, cell surface associated
NDUFAF2 NADH dehydrogenase (ubiquinone) complex I, assembly factor 2
OCLN occludin
PARP4 poly (ADP-ribose) polymerase family, member 4
PBK PDZ binding kinase
PBX3 pre-B-cell leukemia homeobox 3
PGM5 phosphoglucomutase 5
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4
PLIN3 perilipin 3
PNKD paroxysmal nonkinesigenic dyskinesia
PNPLA6 patatin-like phospholipase domain containing 6
PPIC peptidylprolyl isomerase C (cyclophilin C)
PRADC1 protease-associated domain containing 1
PXMP4 peroxisomal membrane protein 4, 24kDa
QKI QKI, KH domain containing, RNA binding
RAI14 retinoic acid induced 14
RHOC ras homolog family member C
SEC11A SEC11 homolog A (S. cerevisiae)
SKA2 spindle and kinetochore associated complex subunit 2
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC39A11 solute carrier family 39, member 11
SLU7 SLU7 splicing factor homolog (S. cerevisiae)
SNAP23 synaptosomal-associated protein, 23kDa
SORBS1 sorbin and SH3 domain containing 1
SPATS2L spermatogenesis associated, serine-rich 2-like
STOML2 stomatin (EPB72)-like 2
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit
TIMM21 translocase of inner mitochondrial membrane 21 homolog (yeast)
TM9SF2 transmembrane 9 superfamily member 2
TMED9 transmembrane emp24 protein transport domain containing 9
TMEM192 transmembrane protein 192
TYSND1 trypsin domain containing 1
UQCC3 ubiquinol-cytochrome c reductase complex assembly factor 3
USO1 USO1 vesicle transport factor
VDAC1 voltage-dependent anion channel 1
VWA8 von Willebrand factor A domain containing 8
YBEY ybeY metallopeptidase (putative)
YBX3 Y box binding protein 3
YIPF5 Yip1 domain family, member 5
ZFC3H1 zinc finger, C3H1-type containing