NCI-H2227 Gene Set

Dataset Sanger Dependency Map Cancer Cell Line Proteomics
Category proteomics
Type cell line
Description cell line derived from Small Cell Lung Carcinoma Tumour (Cell Model Passports, SIDM00730)
External Link https://cellmodelpassports.sanger.ac.uk/passports/SIDM00730
Similar Terms
Downloads & Tools

Genes

196 proteins associated with the cell line NCI-H2227 from the Sanger Dependency Map Cancer Cell Line Proteomics dataset.

Symbol Name
ACIN1 apoptotic chromatin condensation inducer 1
ADNP activity-dependent neuroprotector homeobox
APOE apolipoprotein E
ATAT1 alpha tubulin acetyltransferase 1
ATF2 activating transcription factor 2
ATRX alpha thalassemia/mental retardation syndrome X-linked
BPHL biphenyl hydrolase-like (serine hydrolase)
C19ORF47 chromosome 19 open reading frame 47
CAAP1 caspase activity and apoptosis inhibitor 1
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CBX1 chromobox homolog 1
CBX8 chromobox homolog 8
CCAR2 cell cycle and apoptosis regulator 2
CCSER1 coiled-coil serine-rich protein 1
CEND1 cell cycle exit and neuronal differentiation 1
CHMP2A charged multivesicular body protein 2A
CLU clusterin
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)
CSTF2 cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa
CTSH cathepsin H
CWC15 CWC15 spliceosome-associated protein
DAXX death-domain associated protein
DBT dihydrolipoamide branched chain transacylase E2
DIABLO diablo, IAP-binding mitochondrial protein
DIAPH3 diaphanous-related formin 3
ECH1 enoyl CoA hydratase 1, peroxisomal
EFNB3 ephrin-B3
EPB41 erythrocyte membrane protein band 4.1
ERH enhancer of rudimentary homolog (Drosophila)
GCA grancalcin, EF-hand calcium binding protein
HIBCH 3-hydroxyisobutyryl-CoA hydrolase
HMG20A high mobility group 20A
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like
HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 (H')
HNRNPR heterogeneous nuclear ribonucleoprotein R
HP1BP3 heterochromatin protein 1, binding protein 3
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10
IRF2BP1 interferon regulatory factor 2 binding protein 1
IRF2BPL interferon regulatory factor 2 binding protein-like
KIDINS220 kinase D-interacting substrate, 220kDa
LRRC4B leucine rich repeat containing 4B
MEAF6 MYST/Esa1-associated factor 6
MET MET proto-oncogene, receptor tyrosine kinase
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MYL6B myosin, light chain 6B, alkali, smooth muscle and non-muscle
NCSTN nicastrin
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa
NDUFS5 NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase)
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase)
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
NIPBL Nipped-B homolog (Drosophila)
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae)
NUP62 nucleoporin 62kDa
OXCT1 3-oxoacid CoA transferase 1
OXLD1 oxidoreductase-like domain containing 1
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae)
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor
PHC2 polyhomeotic homolog 2 (Drosophila)
PLD3 phospholipase D family, member 3
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein
PPHLN1 periphilin 1
PPIG peptidylprolyl isomerase G (cyclophilin G)
PRAF2 PRA1 domain family, member 2
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator
PRR3 proline rich 3
PSIP1 PC4 and SFRS1 interacting protein 1
RBM10 RNA binding motif protein 10
RBM4B RNA binding motif protein 4B
RING1 ring finger protein 1
RNF2 ring finger protein 2
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
SAP130 Sin3A-associated protein, 130kDa
SAP18 Sin3A-associated protein, 18kDa
SARS2 seryl-tRNA synthetase 2, mitochondrial
SHTN1 shootin 1
SIN3A SIN3 transcription regulator family member A
SIRT3 sirtuin 3
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SMC6 structural maintenance of chromosomes 6
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1
SRPX sushi-repeat containing protein, X-linked
SUMO1 small ubiquitin-like modifier 1
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast)
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast)
TP53BP1 tumor protein p53 binding protein 1
TPR translocated promoter region, nuclear basket protein
TUBB2B tubulin, beta 2B class IIb
UBQLN2 ubiquilin 2
UQCC2 ubiquinol-cytochrome c reductase complex assembly factor 2
UROS uroporphyrinogen III synthase
USP11 ubiquitin specific peptidase 11
VGF VGF nerve growth factor inducible
VTN vitronectin
ZMYND8 zinc finger, MYND-type containing 8
ZNF512 zinc finger protein 512
ZNF532 zinc finger protein 532
ZNF687 zinc finger protein 687

Symbol Name
ACAA1 acetyl-CoA acyltransferase 1
ACTA1 actin, alpha 1, skeletal muscle
AGO2 argonaute RISC catalytic component 2
ALDH18A1 aldehyde dehydrogenase 18 family, member A1
AMIGO2 adhesion molecule with Ig-like domain 2
ANO6 anoctamin 6
ANXA1 annexin A1
ANXA11 annexin A11
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BRCA2 breast cancer 2, early onset
C5ORF15 chromosome 5 open reading frame 15
CAMK1D calcium/calmodulin-dependent protein kinase ID
CBX4 chromobox homolog 4
CD44 CD44 molecule (Indian blood group)
CDC42 cell division cycle 42
CLIP1 CAP-GLY domain containing linker protein 1
CLPTM1 cleft lip and palate associated transmembrane protein 1
CNN2 calponin 2
COBLL1 cordon-bleu WH2 repeat protein-like 1
COMTD1 catechol-O-methyltransferase domain containing 1
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae)
CRYBB1 crystallin, beta B1
CTBS chitobiase, di-N-acetyl-
DHODH dihydroorotate dehydrogenase (quinone)
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DUSP9 dual specificity phosphatase 9
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EPS8 epidermal growth factor receptor pathway substrate 8
EPS8L2 EPS8-like 2
ETHE1 ethylmalonic encephalopathy 1
EZR ezrin
FGFRL1 fibroblast growth factor receptor-like 1
FN1 fibronectin 1
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2
GCDH glutaryl-CoA dehydrogenase
GHITM growth hormone inducible transmembrane protein
GJA1 gap junction protein, alpha 1, 43kDa
GRK6 G protein-coupled receptor kinase 6
HLA-A major histocompatibility complex, class I, A
HLA-G major histocompatibility complex, class I, G
IDE insulin-degrading enzyme
IGSF1 immunoglobulin superfamily, member 1
JUND jun D proto-oncogene
LOC100131795 uncharacterized LOC100131795
LOC105371242 peptidyl-prolyl cis-trans isomerase A-like 4G
LOC105373020 uncharacterized LOC105373020
LRRC7 leucine rich repeat containing 7
LUM lumican
MEF2B myocyte enhancer factor 2B
MRPS10 mitochondrial ribosomal protein S10
MSN moesin
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
MYH9 myosin, heavy chain 9, non-muscle
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle
NEK5 NIMA-related kinase 5
NELL1 NEL-like 1 (chicken)
NIT2 nitrilase family, member 2
PCLO piccolo presynaptic cytomatrix protein
PDLIM1 PDZ and LIM domain 1
PHLDB2 pleckstrin homology-like domain, family B, member 2
PKLR pyruvate kinase, liver and RBC
PNP purine nucleoside phosphorylase
PPCS phosphopantothenoylcysteine synthetase
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PXDN peroxidasin
QPCTL glutaminyl-peptide cyclotransferase-like
QSER1 glutamine and serine rich 1
RIOK1 RIO kinase 1
RNF168 ring finger protein 168, E3 ubiquitin protein ligase
RNF5 ring finger protein 5, E3 ubiquitin protein ligase
RPL37A ribosomal protein L37a
RPP30 ribonuclease P/MRP 30kDa subunit
RSU1 Ras suppressor protein 1
RWDD1 RWD domain containing 1
RYR1 ryanodine receptor 1 (skeletal)
SEC61G Sec61 gamma subunit
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
SLC39A11 solute carrier family 39, member 11
SLCO4A1 solute carrier organic anion transporter family, member 4A1
SMYD5 SMYD family member 5
TELO2 telomere maintenance 2
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast)
TK1 thymidine kinase 1, soluble
TMF1 TATA element modulatory factor 1
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRO trophinin
TSLIG3A tRNA splicing ligase complex subunit 3A
UBA5 ubiquitin-like modifier activating enzyme 5
URI1 URI1, prefoldin-like chaperone
USP15 ubiquitin specific peptidase 15
VASP vasodilator-stimulated phosphoprotein
VWA5A von Willebrand factor A domain containing 5A
VWA5B2 von Willebrand factor A domain containing 5B2
WDR6 WD repeat domain 6
ZCCHC9 zinc finger, CCHC domain containing 9
ZYX zyxin