NCI-H2347 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
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Genes

268 genes with high or low expression in NCI-H2347 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 3.06009
RABGGTA Rab geranylgeranyltransferase, alpha subunit 2.95538
CCNB1 cyclin B1 2.84482
NME6 NME/NM23 nucleoside diphosphate kinase 6 2.59476
IL37 interleukin 37 2.52737
RBMS2 RNA binding motif, single stranded interacting protein 2 2.47662
ERBB2IP erbb2 interacting protein 2.37434
MAPK13 mitogen-activated protein kinase 13 2.27979
GPR52 G protein-coupled receptor 52 2.26378
TCP11 t-complex 11, testis-specific 2.24585
NEDD8 neural precursor cell expressed, developmentally down-regulated 8 2.20571
ANXA2P1 annexin A2 pseudogene 1 2.19316
EPHX3 epoxide hydrolase 3 2.18261
NR3C2 nuclear receptor subfamily 3, group C, member 2 2.0998
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha 2.08181
PRKCZ protein kinase C, zeta 2.07128
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1 2.05765
DUSP10 dual specificity phosphatase 10 2.04919
NPC2 Niemann-Pick disease, type C2 2.01397
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 1.99445
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 1.97564
PDLIM2 PDZ and LIM domain 2 (mystique) 1.97241
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa 1.94058
CD47 CD47 molecule 1.90838
ALOX15B arachidonate 15-lipoxygenase, type B 1.90553
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 1.83534
EFHD2 EF-hand domain family, member D2 1.80754
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 1.80415
CLTB clathrin, light chain B 1.78728
HYI hydroxypyruvate isomerase (putative) 1.78722
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B 1.78269
S100A5 S100 calcium binding protein A5 1.76981
TOP1 topoisomerase (DNA) I 1.75666
RAB15 RAB15, member RAS oncogene family 1.75583
MAP7D1 MAP7 domain containing 1 1.75017
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 1.74913
RAB11FIP1 RAB11 family interacting protein 1 (class I) 1.73378
CST6 cystatin E/M 1.72997
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 1.72233
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 1.71003
GLRX glutaredoxin (thioltransferase) 1.70666
APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A 1.68006
DUSP13 dual specificity phosphatase 13 1.67942
NEUROD4 neuronal differentiation 4 1.67542
CLCF1 cardiotrophin-like cytokine factor 1 1.65487
STAG3 stromal antigen 3 1.64945
RHOF ras homolog family member F (in filopodia) 1.63829
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa 1.6337
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3 1.63302
TUSC2 tumor suppressor candidate 2 1.63252
MSN moesin 1.63237
TUBB4B tubulin, beta 4B class IVb 1.62468
PRDM9 PR domain containing 9 1.6239
MSMO1 methylsterol monooxygenase 1 1.6228
ABHD5 abhydrolase domain containing 5 1.61708
BAG3 BCL2-associated athanogene 3 1.61186
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit 1.61112
ZCWPW1 zinc finger, CW type with PWWP domain 1 1.60706
UBE2E1 ubiquitin-conjugating enzyme E2E 1 1.59415
CFLAR CASP8 and FADD-like apoptosis regulator 1.59291
LHX6 LIM homeobox 6 1.59284
MTMR8 myotubularin related protein 8 1.583
PLP2 proteolipid protein 2 (colonic epithelium-enriched) 1.58055
TRNAU1AP tRNA selenocysteine 1 associated protein 1 1.57661
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7 1.56133
ADGRF5 adhesion G protein-coupled receptor F5 1.55336
ALDOB aldolase B, fructose-bisphosphate 1.55304
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1 1.53576
MYO6 myosin VI 1.52842
CLIC1 chloride intracellular channel 1 1.52444
SUMO3 small ubiquitin-like modifier 3 1.51441
FABP3 fatty acid binding protein 3, muscle and heart 1.51106
DUSP14 dual specificity phosphatase 14 1.50991
KRT7 keratin 7, type II 1.50818
LRRC20 leucine rich repeat containing 20 1.49846
LMO3 LIM domain only 3 (rhombotin-like 2) 1.48469
IL23A interleukin 23, alpha subunit p19 1.47968
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 1.47959
FDPS farnesyl diphosphate synthase 1.47867
GIPC1 GIPC PDZ domain containing family, member 1 1.47859
PPP4R1 protein phosphatase 4, regulatory subunit 1 1.47114
EBP emopamil binding protein (sterol isomerase) 1.46831
MPRIP myosin phosphatase Rho interacting protein 1.46531
VSX1 visual system homeobox 1 1.46309
PLIN1 perilipin 1 1.46009
MAP3K9 mitogen-activated protein kinase kinase kinase 9 1.45787
BTNL2 butyrophilin-like 2 1.45444
ACO1 aconitase 1, soluble 1.45442
PGBD5 piggyBac transposable element derived 5 1.45234
CCKAR cholecystokinin A receptor 1.45001
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) 1.44952
KIF20A kinesin family member 20A 1.44322
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B 1.44315
TMOD3 tropomodulin 3 (ubiquitous) 1.43982
RABIF RAB interacting factor 1.43606
CAPN2 calpain 2, (m/II) large subunit 1.43467
FLNC filamin C, gamma 1.42912
KIF20B kinesin family member 20B 1.42724
ACOXL acyl-CoA oxidase-like 1.42653
PDE3A phosphodiesterase 3A, cGMP-inhibited 1.42394
BHMT2 betaine--homocysteine S-methyltransferase 2 1.42181
KPNA1 karyopherin alpha 1 (importin alpha 5) 1.4216
STEAP4 STEAP family member 4 1.41777

low expression

Symbol Name Standardized Value
COG7 component of oligomeric golgi complex 7 -3.08968
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 -3.08833
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) -3.05682
PIGO phosphatidylinositol glycan anchor biosynthesis, class O -2.84406
LIPT1 lipoyltransferase 1 -2.78769
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2) -2.77899
LCMT1 leucine carboxyl methyltransferase 1 -2.76812
SMG6 SMG6 nonsense mediated mRNA decay factor -2.70349
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) -2.69811
PARN poly(A)-specific ribonuclease -2.63946
KDM4C lysine (K)-specific demethylase 4C -2.55693
ZBTB5 zinc finger and BTB domain containing 5 -2.42445
CFDP1 craniofacial development protein 1 -2.39001
MIA3 melanoma inhibitory activity family, member 3 -2.38909
PEX3 peroxisomal biogenesis factor 3 -2.38248
ZNF200 zinc finger protein 200 -2.35216
CRADD CASP2 and RIPK1 domain containing adaptor with death domain -2.33067
TTC17 tetratricopeptide repeat domain 17 -2.32942
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 -2.29606
COQ9 coenzyme Q9 -2.26706
TIA1 TIA1 cytotoxic granule-associated RNA binding protein -2.2422
ZNF263 zinc finger protein 263 -2.23757
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 -2.22792
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related) -2.20705
NDUFAF1 NADH dehydrogenase (ubiquinone) complex I, assembly factor 1 -2.19935
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 -2.16356
REV1 REV1, polymerase (DNA directed) -2.12529
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2 -2.11493
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase -2.10509
ASF1A anti-silencing function 1A histone chaperone -2.09933
IL11RA interleukin 11 receptor, alpha -2.07947
R3HDM2 R3H domain containing 2 -2.07534
COMMD1 copper metabolism (Murr1) domain containing 1 -2.06204
ADGRV1 adhesion G protein-coupled receptor V1 -2.05541
TGOLN2 trans-golgi network protein 2 -2.03868
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 -2.02251
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -1.96633
SECISBP2 SECIS binding protein 2 -1.95916
ZAK sterile alpha motif and leucine zipper containing kinase AZK -1.95682
KIAA0355 KIAA0355 -1.95016
TSC1 tuberous sclerosis 1 -1.93235
GOLGA8B golgin A8 family, member B -1.93187
CDC42SE2 CDC42 small effector 2 -1.91179
FBXO38 F-box protein 38 -1.90777
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae) -1.90685
LRRC8D leucine rich repeat containing 8 family, member D -1.90648
ARRB2 arrestin, beta 2 -1.90525
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease -1.90185
FTO fat mass and obesity associated -1.89862
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 -1.88754
EFHC1 EF-hand domain (C-terminal) containing 1 -1.85997
RPAIN RPA interacting protein -1.84389
MSX1 msh homeobox 1 -1.8261
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit -1.82575
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) -1.80243
STK38L serine/threonine kinase 38 like -1.78675
GABARAPL2 GABA(A) receptor-associated protein-like 2 -1.78618
PAN2 PAN2 poly(A) specific ribonuclease subunit -1.77655
RINT1 RAD50 interactor 1 -1.77129
FRS2 fibroblast growth factor receptor substrate 2 -1.76894
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -1.76572
CBFB core-binding factor, beta subunit -1.75119
KIAA0430 KIAA0430 -1.74716
PLP1 proteolipid protein 1 -1.73454
RAG1 recombination activating gene 1 -1.71708
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2 -1.71679
APOM apolipoprotein M -1.71081
RNF167 ring finger protein 167 -1.70297
TSPYL4 TSPY-like 4 -1.70189
TTC30A tetratricopeptide repeat domain 30A -1.7018
SPG11 spastic paraplegia 11 (autosomal recessive) -1.7011
PREP prolyl endopeptidase -1.69571
INCENP inner centromere protein antigens 135/155kDa -1.69531
ANGPT1 angiopoietin 1 -1.68839
CSTA cystatin A (stefin A) -1.68818
FAM120C family with sequence similarity 120C -1.68555
ZNF589 zinc finger protein 589 -1.68548
ITGA10 integrin, alpha 10 -1.66986
NTF3 neurotrophin 3 -1.65623
SPDEF SAM pointed domain containing ETS transcription factor -1.65194
KDM4A lysine (K)-specific demethylase 4A -1.64024
CPA4 carboxypeptidase A4 -1.64015
CREB5 cAMP responsive element binding protein 5 -1.63887
TCF12 transcription factor 12 -1.63548
GCC2 GRIP and coiled-coil domain containing 2 -1.62989
CTAGE1 cutaneous T-cell lymphoma-associated antigen 1 -1.62888
CREM cAMP responsive element modulator -1.62698
ZNF12 zinc finger protein 12 -1.62628
CDC40 cell division cycle 40 -1.62579
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) -1.62476
TERF2IP telomeric repeat binding factor 2, interacting protein -1.62348
WDR59 WD repeat domain 59 -1.62073
SP4 Sp4 transcription factor -1.60974
PHF20 PHD finger protein 20 -1.60267
CD164 CD164 molecule, sialomucin -1.60231
LONP2 lon peptidase 2, peroxisomal -1.59891
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium) -1.59772
VAV3 vav 3 guanine nucleotide exchange factor -1.59364
CTSK cathepsin K -1.59315
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -1.58598
MPV17 MpV17 mitochondrial inner membrane protein -1.57997
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase -1.57542
CHPT1 choline phosphotransferase 1 -1.5652
BRE brain and reproductive organ-expressed (TNFRSF1A modulator) -1.5644
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -1.56365
PTCD1 pentatricopeptide repeat domain 1 -1.56225
CEL carboxyl ester lipase -1.56219
RNASE4 ribonuclease, RNase A family, 4 -1.55791
OMD osteomodulin -1.55322
UTP14C UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast) -1.54921
QTRT1 queuine tRNA-ribosyltransferase 1 -1.54629
STARD5 StAR-related lipid transfer (START) domain containing 5 -1.5389
THADA thyroid adenoma associated -1.53825
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal) -1.53801
ZMIZ1 zinc finger, MIZ-type containing 1 -1.53217
KDELC1 KDEL (Lys-Asp-Glu-Leu) containing 1 -1.52933
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin -1.52674
ZSCAN32 zinc finger and SCAN domain containing 32 -1.52393
GP5 glycoprotein V (platelet) -1.51831
XPA xeroderma pigmentosum, complementation group A -1.50999
DMXL1 Dmx-like 1 -1.50882
RBBP6 retinoblastoma binding protein 6 -1.50551
MRPL34 mitochondrial ribosomal protein L34 -1.50479
ABI3BP ABI family, member 3 (NESH) binding protein -1.49879
TUBGCP4 tubulin, gamma complex associated protein 4 -1.49868
THUMPD1 THUMP domain containing 1 -1.49851
AKAP11 A kinase (PRKA) anchor protein 11 -1.49368
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 -1.49022
NHLH2 nescient helix loop helix 2 -1.48668
FNDC3A fibronectin type III domain containing 3A -1.48218
TM2D1 TM2 domain containing 1 -1.4817
DMD dystrophin -1.47988
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B -1.47616
PAPOLG poly(A) polymerase gamma -1.47615
PAPPA2 pappalysin 2 -1.47585
BTN3A2 butyrophilin, subfamily 3, member A2 -1.46879
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit -1.46448
HOXA2 homeobox A2 -1.46009
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -1.45872
FIG4 FIG4 phosphoinositide 5-phosphatase -1.45688
POLR1D polymerase (RNA) I polypeptide D, 16kDa -1.45141
NCR1 natural cytotoxicity triggering receptor 1 -1.44703
SCUBE3 signal peptide, CUB domain, EGF-like 3 -1.44672
NRF1 nuclear respiratory factor 1 -1.44646
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae) -1.44523
ZNF235 zinc finger protein 235 -1.44417
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -1.44361
PREPL prolyl endopeptidase-like -1.44249
MAD2L1BP MAD2L1 binding protein -1.44192
MED23 mediator complex subunit 23 -1.44098
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) -1.44091
DHODH dihydroorotate dehydrogenase (quinone) -1.43884
TP53I11 tumor protein p53 inducible protein 11 -1.43824
ZFC3H1 zinc finger, C3H1-type containing -1.43571
IQCG IQ motif containing G -1.43538
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1) -1.43374
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) -1.43139
JAK2 Janus kinase 2 -1.42962
FAM96B family with sequence similarity 96, member B -1.42691
RABEP1 rabaptin, RAB GTPase binding effector protein 1 -1.4231
KALRN kalirin, RhoGEF kinase -1.42258
SLC35E2 solute carrier family 35, member E2 -1.41971
PGK2 phosphoglycerate kinase 2 -1.4191
RSPH14 radial spoke head 14 homolog (Chlamydomonas) -1.41745
CALML4 calmodulin-like 4 -1.41557