NCI-H2369 Gene Set

Dataset Sanger Dependency Map Cancer Cell Line Proteomics
Category proteomics
Type cell line
Description cell line derived from lung (Klijn et al., Nat. Biotechnol., 2015)
External Link https://cellmodelpassports.sanger.ac.uk/passports/SIDM00104
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Genes

200 proteins associated with the cell line NCI-H2369 from the Sanger Dependency Map Cancer Cell Line Proteomics dataset.

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
AIDA axin interactor, dorsalization associated
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AKT1S1 AKT1 substrate 1 (proline-rich)
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B
ANLN anillin, actin binding protein
BAG3 BCL2-associated athanogene 3
BICD2 bicaudal D homolog 2 (Drosophila)
BLVRA biliverdin reductase A
BSDC1 BSD domain containing 1
C2CD2 C2 calcium-dependent domain containing 2
CAP2 CAP, adenylate cyclase-associated protein, 2 (yeast)
CAPS calcyphosine
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4
CENPH centromere protein H
CEP76 centrosomal protein 76kDa
CFL2 cofilin 2 (muscle)
CIT citron rho-interacting serine/threonine kinase
CLIC4 chloride intracellular channel 4
CNOT12 CCR4-NOT transcription complex subunit 12
COMMD9 COMM domain containing 9
COPS7A COP9 signalosome subunit 7A
CORO1C coronin, actin binding protein, 1C
CROCC ciliary rootlet coiled-coil, rootletin
CSRP1 cysteine and glycine-rich protein 1
CUTA cutA divalent cation tolerance homolog (E. coli)
DCTN5 dynactin 5 (p25)
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
DYNLRB1 dynein, light chain, roadblock-type 1
EEA1 early endosome antigen 1
EHD3 EH-domain containing 3
EIF3I eukaryotic translation initiation factor 3, subunit I
EPB41L2 erythrocyte membrane protein band 4.1-like 2
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1
FAM114A1 family with sequence similarity 114, member A1
FAM168A family with sequence similarity 168, member A
FLNC filamin C, gamma
GINS1 GINS complex subunit 1 (Psf1 homolog)
GOLGA3 golgin A3
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
HMGN5 high mobility group nucleosome binding domain 5
IL18 interleukin 18
IL18R1 interleukin 18 receptor 1
IVL involucrin
JMJD6 jumonji domain containing 6
KCMF1 potassium channel modulatory factor 1
LIMA1 LIM domain and actin binding 1
LOC105375357 uncharacterized LOC105375357
LXN latexin
MAP3K20 mitogen-activated protein kinase kinase kinase 20
MCM10 minichromosome maintenance complex component 10
MEN1 multiple endocrine neoplasia I
NAA35 N(alpha)-acetyltransferase 35, NatC auxiliary subunit
NAA40 N(alpha)-acetyltransferase 40, NatD catalytic subunit
NMRK2 nicotinamide riboside kinase 2
NUDCD3 NudC domain containing 3
PAPOLG poly(A) polymerase gamma
PEA15 phosphoprotein enriched in astrocytes 15
PECR peroxisomal trans-2-enoyl-CoA reductase
POLRMT polymerase (RNA) mitochondrial (DNA directed)
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PXN paxillin
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
RCN3 reticulocalbin 3, EF-hand calcium binding domain
REXO2 RNA exonuclease 2
RHOA ras homolog family member A
RPS3P1 ribosomal protein S3 pseudogene 1
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3
SH3KBP1 SH3-domain kinase binding protein 1
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SMAP1 small ArfGAP 1
SMS spermine synthase
SOD2 superoxide dismutase 2, mitochondrial
SPPL2A signal peptide peptidase like 2A
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
SVIP small VCP/p97-interacting protein
TMSB10 thymosin beta 10
TNS3 tensin 3
TRIP13 thyroid hormone receptor interactor 13
TRPV2 transient receptor potential cation channel, subfamily V, member 2
TUBA1C tubulin, alpha 1c
TUBB6 tubulin, beta 6 class V
TXNL1 thioredoxin-like 1
TXNRD1 thioredoxin reductase 1
TYMP thymidine phosphorylase
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1
UTP4 UTP4 small subunit processome component
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae)
VPS29 vacuolar protein sorting 29 homolog (S. cerevisiae)
WDR4 WD repeat domain 4
YJU2 YJU2 splicing factor homolog
ZNF185 zinc finger protein 185 (LIM domain)

Symbol Name
ACTG1P22 actin gamma 1 pseudogene 22
AGPS alkylglycerone phosphate synthase
AK3 adenylate kinase 3
ALG1 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
BCAP29 B-cell receptor-associated protein 29
C1QBP complement component 1, q subcomponent binding protein
CCDC97 coiled-coil domain containing 97
CDK18 cyclin-dependent kinase 18
CEPT1 choline/ethanolamine phosphotransferase 1
CHD5 chromodomain helicase DNA binding protein 5
CLCN3 chloride channel, voltage-sensitive 3
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3
COX14 COX14 cytochrome c oxidase assembly factor
CPOX coproporphyrinogen oxidase
CUTC cutC copper transporter
DAZAP1 DAZ associated protein 1
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24
DHODH dihydroorotate dehydrogenase (quinone)
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8
DKC1 dyskeratosis congenita 1, dyskerin
DNAJB11 DnaJ (Hsp40) homolog, subfamily B, member 11
EYA3 EYA transcriptional coactivator and phosphatase 3
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FAM162A family with sequence similarity 162, member A
FBL fibrillarin
FNIP2 folliculin interacting protein 2
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GNG5 guanine nucleotide binding protein (G protein), gamma 5
HNRNPL heterogeneous nuclear ribonucleoprotein L
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1
INTS4 integrator complex subunit 4
KIF18A kinesin family member 18A
KRT79 keratin 79, type II
LARS2 leucyl-tRNA synthetase 2, mitochondrial
MIPEP mitochondrial intermediate peptidase
MIR513A1 microRNA 513a-1
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MRPL20 mitochondrial ribosomal protein L20
MRPS26 mitochondrial ribosomal protein S26
MTA1 metastasis associated 1
NCOA7 nuclear receptor coactivator 7
NDUFB1 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
NFIC nuclear factor I/C (CCAAT-binding transcription factor)
NOP56 NOP56 ribonucleoprotein
NOP58 NOP58 ribonucleoprotein
NT5C 5', 3'-nucleotidase, cytosolic
NUP210 nucleoporin 210kDa
NUP54 nucleoporin 54kDa
PET100 PET100 homolog (S. cerevisiae)
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PHYKPL 5-phosphohydroxy-L-lysine phospho-lyase
PLAG1 pleiomorphic adenoma gene 1
POLR1A polymerase (RNA) I polypeptide A, 194kDa
POU2F1 POU class 2 homeobox 1
PRKD2 protein kinase D2
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
PRPF8 pre-mRNA processing factor 8
PSPC1 paraspeckle component 1
PTGFRN prostaglandin F2 receptor inhibitor
RABGAP1 RAB GTPase activating protein 1
RABGAP1L RAB GTPase activating protein 1-like
RBM15 RNA binding motif protein 15
RBM17 RNA binding motif protein 17
RCOR3 REST corepressor 3
SLC25A19 solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19
SLC38A10 solute carrier family 38, member 10
SLMAP sarcolemma associated protein
SMYD3 SET and MYND domain containing 3
STK11IP serine/threonine kinase 11 interacting protein
STRIP1 striatin interacting protein 1
SUPT4H1 suppressor of Ty 4 homolog 1 (S. cerevisiae)
SURF2 surfeit 2
SYNE3 spectrin repeat containing, nuclear envelope family member 3
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TBK1 TANK-binding kinase 1
TFAM transcription factor A, mitochondrial
TGFB2 transforming growth factor, beta 2
THRAP3 thyroid hormone receptor associated protein 3
TMEM87A transmembrane protein 87A
TMSB4Y thymosin beta 4, Y-linked
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast)
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast)
TOMM5 translocase of outer mitochondrial membrane 5 homolog (yeast)
TOP1 topoisomerase (DNA) I
TP53RK TP53 regulating kinase
TREX1 three prime repair exonuclease 1
TTC5 tetratricopeptide repeat domain 5
TTI1 TELO2 interacting protein 1
TYK2 tyrosine kinase 2
UHRF1BP1 UHRF1 binding protein 1
UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1
UQCRC1 ubiquinol-cytochrome c reductase core protein I
UQCRC2 ubiquinol-cytochrome c reductase core protein II
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa
WDR18 WD repeat domain 18
WDR3 WD repeat domain 3
XYLT2 xylosyltransferase II
YLPM1 YLP motif containing 1