NCI-H2373 Gene Set

Dataset Sanger Dependency Map Cancer Cell Line Proteomics
Category proteomics
Type cell line
Description cell line derived from lung (Klijn et al., Nat. Biotechnol., 2015)
External Link https://cellmodelpassports.sanger.ac.uk/passports/SIDM00103
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Genes

197 proteins associated with the cell line NCI-H2373 from the Sanger Dependency Map Cancer Cell Line Proteomics dataset.

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ACO1 aconitase 1, soluble
ACSL4 acyl-CoA synthetase long-chain family member 4
ACTN2 actinin, alpha 2
ACTN4 actinin, alpha 4
AHNAK2 AHNAK nucleoprotein 2
AKAP2 A kinase (PRKA) anchor protein 2
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ALPPL2 alkaline phosphatase, placental-like 2
ANXA5 annexin A5
AP2A1 adaptor-related protein complex 2, alpha 1 subunit
AP2B1 adaptor-related protein complex 2, beta 1 subunit
AP2M1 adaptor-related protein complex 2, mu 1 subunit
AP2S1 adaptor-related protein complex 2, sigma 1 subunit
AP3B1 adaptor-related protein complex 3, beta 1 subunit
APIP APAF1 interacting protein
ARF6 ADP-ribosylation factor 6
ARL1 ADP-ribosylation factor-like 1
ARL8A ADP-ribosylation factor-like 8A
ARL8B ADP-ribosylation factor-like 8B
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
BRI3 brain protein I3
BZW1 basic leucine zipper and W2 domains 1
CAPN2 calpain 2, (m/II) large subunit
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative)
CDC50A cell division cycle 50 P4-ATPase accessory subunit A
CLIC4 chloride intracellular channel 4
CLTC clathrin, heavy chain (Hc)
CORO1C coronin, actin binding protein, 1C
COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like
CPNE3 copine III
CYFIP1 cytoplasmic FMR1 interacting protein 1
DCTD dCMP deaminase
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13
ECI2 enoyl-CoA delta isomerase 2
EEA1 early endosome antigen 1
EHD2 EH-domain containing 2
EZR ezrin
FLNC filamin C, gamma
FYCO1 FYVE and coiled-coil domain containing 1
GBE1 glucan (1,4-alpha-), branching enzyme 1
GNPDA1 glucosamine-6-phosphate deaminase 1
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
HSPB6 heat shock protein, alpha-crystallin-related, B6
ILK integrin-linked kinase
IQGAP1 IQ motif containing GTPase activating protein 1
KANK2 KN motif and ankyrin repeat domains 2
LACTB lactamase, beta
LIMA1 LIM domain and actin binding 1
LIPA lipase A, lysosomal acid, cholesterol esterase
LOC105373020 uncharacterized LOC105373020
MACF1 microtubule-actin crosslinking factor 1
MBLAC2 metallo-beta-lactamase domain containing 2
MFGE8 milk fat globule-EGF factor 8 protein
MGARP mitochondria-localized glutamic acid-rich protein
MGLL monoglyceride lipase
MME membrane metallo-endopeptidase
MRS2 MRS2 magnesium transporter
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha
NEK7 NIMA-related kinase 7
NPC1 Niemann-Pick disease, type C1
PGRMC2 progesterone receptor membrane component 2
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PLAA phospholipase A2-activating protein
PRPS1 phosphoribosyl pyrophosphate synthetase 1
PYM1 PYM homolog 1, exon junction complex associated factor
RAB32 RAB32, member RAS oncogene family
RAB7A RAB7A, member RAS oncogene family
RAB8B RAB8B, member RAS oncogene family
RIC8A RIC8 guanine nucleotide exchange factor A
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae)
RND3 Rho family GTPase 3
SAR1A secretion associated, Ras related GTPase 1A
SCAMP1 secretory carrier membrane protein 1
SDCBP syndecan binding protein (syntenin)
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SFXN3 sideroflexin 3
SH2D4A SH2 domain containing 4A
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SPAST spastin
STX4 syntaxin 4
STXBP3 syntaxin binding protein 3
TDRD5 tudor domain containing 5
TLN1 talin 1
TLN2 talin 2
TRIM23 tripartite motif containing 23
TUBB6 tubulin, beta 6 class V
TXNRD1 thioredoxin reductase 1
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UBXN6 UBX domain protein 6
VAT1 vesicle amine transport 1
VPS26A vacuolar protein sorting 26 homolog A (S. pombe)
VPS29 vacuolar protein sorting 29 homolog (S. cerevisiae)
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae)

Symbol Name
ACIN1 apoptotic chromatin condensation inducer 1
AGR2 anterior gradient 2
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
BIRC5 baculoviral IAP repeat containing 5
BLOC1S5 biogenesis of lysosomal organelles complex-1, subunit 5, muted
CBR4 carbonyl reductase 4
CCDC59 coiled-coil domain containing 59
CENPC centromere protein C
CHDH choline dehydrogenase
CNOT7 CCR4-NOT transcription complex, subunit 7
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa
EHMT2 euchromatic histone-lysine N-methyltransferase 2
EML3 echinoderm microtubule associated protein like 3
FADS1 fatty acid desaturase 1
FER1L4 fer-1-like family member 4, pseudogene (functional)
FIP1L1 factor interacting with PAPOLA and CPSF1
GMEB2 glucocorticoid modulatory element binding protein 2
GPATCH4 G patch domain containing 4
GPX7 glutathione peroxidase 7
GTF2B general transcription factor IIB
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa
GTPBP1 GTP binding protein 1
GXYLT1 glucoside xylosyltransferase 1
HAX1 HCLS1 associated protein X-1
HDAC1 histone deacetylase 1
HELZ2 helicase with zinc finger 2, transcriptional coactivator
HIPK2 homeodomain interacting protein kinase 2
HMGN2 high mobility group nucleosomal binding domain 2
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B
HYOU1 hypoxia up-regulated 1
INCENP inner centromere protein antigens 135/155kDa
INTS12 integrator complex subunit 12
KDM1B lysine (K)-specific demethylase 1B
KIF3B kinesin family member 3B
LYAR Ly1 antibody reactive
MAEA macrophage erythroblast attacher
MARCKSL1 MARCKS-like 1
MEAF6 MYST/Esa1-associated factor 6
MRPL1 mitochondrial ribosomal protein L1
MTX3 metaxin 3
MYCBP MYC binding protein
NCALD neurocalcin delta
NCAPD3 non-SMC condensin II complex, subunit D3
NOM1 nucleolar protein with MIF4G domain 1
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NUCLEOLIN nucleolin multifunctional protein
NUP50 nucleoporin 50kDa
NUS1 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae)
OSBPL2 oxysterol binding protein-like 2
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
PBRM1 polybromo 1
PDS5B PDS5 cohesin associated factor B
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
POLDIP3 polymerase (DNA-directed), delta interacting protein 3
PPHLN1 periphilin 1
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D
PRR12 proline rich 12
PVOP2 Pelvic organ prolapse, susceptibility to, 2
QRICH1 glutamine-rich 1
RAB44 RAB44, member RAS oncogene family
RAI1 retinoic acid induced 1
RANGRF RAN guanine nucleotide release factor
RBM10 RNA binding motif protein 10
RBM47 RNA binding motif protein 47
RBM5 RNA binding motif protein 5
RCC1 regulator of chromosome condensation 1
RCC2 regulator of chromosome condensation 2
RCOR1 REST corepressor 1
RFXAP regulatory factor X-associated protein
SAMD1 sterile alpha motif domain containing 1
SART1 squamous cell carcinoma antigen recognized by T cells
SCAF1 SR-related CTD-associated factor 1
SFXN1 sideroflexin 1
SIN3A SIN3 transcription regulator family member A
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC25A46 solute carrier family 25, member 46
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
SPN sialophorin
SPTY2D1 SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae)
SRRM2 serine/arginine repetitive matrix 2
THUMPD3 THUMP domain containing 3
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TONSL tonsoku-like, DNA repair protein
TOX4 TOX high mobility group box family member 4
TPR translocated promoter region, nuclear basket protein
TPX2 TPX2, microtubule-associated
TREX1 three prime repair exonuclease 1
TXLNG taxilin gamma
WBP11 WW domain binding protein 11
WDHD1 WD repeat and HMG-box DNA binding protein 1
WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
WTAP Wilms tumor 1 associated protein
YIPF1 Yip1 domain family, member 1
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing
ZC3H11A zinc finger CCCH-type containing 11A
ZNF24 zinc finger protein 24
ZNF593 zinc finger protein 593