NCI-H2461 Gene Set

Dataset Sanger Dependency Map Cancer Cell Line Proteomics
Category proteomics
Type cell line
Description cell line derived from lung (Klijn et al., Nat. Biotechnol., 2015)
External Link https://cellmodelpassports.sanger.ac.uk/passports/SIDM00102
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Genes

198 proteins associated with the cell line NCI-H2461 from the Sanger Dependency Map Cancer Cell Line Proteomics dataset.

Symbol Name
ACACA acetyl-CoA carboxylase alpha
ACBD6 acyl-CoA binding domain containing 6
ADAM1A ADAM metallopeptidase domain 1A (pseudogene)
ALPK3 alpha-kinase 3
ANLN anillin, actin binding protein
ASB6 ankyrin repeat and SOCS box containing 6
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
BAG3 BCL2-associated athanogene 3
BAG6 BCL2-associated athanogene 6
BAZ1A bromodomain adjacent to zinc finger domain, 1A
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
C8ORF33 chromosome 8 open reading frame 33
CAMKV CaM kinase-like vesicle-associated
CDK17 cyclin-dependent kinase 17
CEP170 centrosomal protein 170kDa
CLCN7 chloride channel, voltage-sensitive 7
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DBNL drebrin-like
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
EEA1 early endosome antigen 1
EFL1 elongation factor like GTPase 1
EIF6 eukaryotic translation initiation factor 6
EML3 echinoderm microtubule associated protein like 3
ERC2 ELKS/RAB6-interacting/CAST family member 2
EVC2 Ellis van Creveld syndrome 2
EXOC7 exocyst complex component 7
FLNC filamin C, gamma
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GNS glucosamine (N-acetyl)-6-sulfatase
GPATCH3 G patch domain containing 3
HABP4 hyaluronan binding protein 4
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
HIBADH 3-hydroxyisobutyrate dehydrogenase
HSF1 heat shock transcription factor 1
HSPB8 heat shock 22kDa protein 8
IGF2R insulin-like growth factor 2 receptor
ITGB5 integrin, beta 5
LARP4 La ribonucleoprotein domain family, member 4
LASP1 LIM and SH3 protein 1
LOC100653005
LOC105371242 peptidyl-prolyl cis-trans isomerase A-like 4G
LOC105375357 uncharacterized LOC105375357
LRRK1 leucine-rich repeat kinase 1
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MAP1A microtubule-associated protein 1A
MCM10 minichromosome maintenance complex component 10
MME membrane metallo-endopeptidase
NCOR2 nuclear receptor corepressor 2
NEDD1 neural precursor cell expressed, developmentally down-regulated 1
NKPD1 NTPase, KAP family P-loop domain containing 1
NR2C2 nuclear receptor subfamily 2, group C, member 2
NSMCE1 non-SMC element 1 homolog (S. cerevisiae)
NT5DC2 5'-nucleotidase domain containing 2
NUDCD3 NudC domain containing 3
NUP214 nucleoporin 214kDa
PATL1 protein associated with topoisomerase II homolog 1 (yeast)
PCYT1A phosphate cytidylyltransferase 1, choline, alpha
PDE4DIP phosphodiesterase 4D interacting protein
PEA15 phosphoprotein enriched in astrocytes 15
PEX1 peroxisomal biogenesis factor 1
PEX11B peroxisomal biogenesis factor 11 beta
PLBD2 phospholipase B domain containing 2
PPTC7 PTC7 protein phosphatase homolog (S. cerevisiae)
PRDX6 peroxiredoxin 6
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PURB purine-rich element binding protein B
PXN paxillin
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RND3 Rho family GTPase 3
RPP38 ribonuclease P/MRP 38kDa subunit
RPS4Y1 ribosomal protein S4, Y-linked 1
SART3 squamous cell carcinoma antigen recognized by T cells 3
SCRN1 secernin 1
SDCBP syndecan binding protein (syntenin)
SDSL serine dehydratase-like
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SNU13 small nuclear ribonucleoprotein 13
SNX3 sorting nexin 3
SQSTM1 sequestosome 1
TDP2 tyrosyl-DNA phosphodiesterase 2
TNS3 tensin 3
TPD52L2 tumor protein D52-like 2
TPPP3 tubulin polymerization-promoting protein family member 3
TRAF2 TNF receptor-associated factor 2
TSC1 tuberous sclerosis 1
TSG101 tumor susceptibility 101
TXNRD1 thioredoxin reductase 1
UNC119B unc-119 homolog B (C. elegans)
VAT1 vesicle amine transport 1
WBP2 WW domain binding protein 2
WDR27 WD repeat domain 27
YIPF4 Yip1 domain family, member 4
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing
YTHDC1 YTH domain containing 1
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3
ZNF622 zinc finger protein 622

Symbol Name
ACIN1 apoptotic chromatin condensation inducer 1
ADAM15 ADAM metallopeptidase domain 15
ADGRG1 adhesion G protein-coupled receptor G1
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa
BCAT1 branched chain amino-acid transaminase 1, cytosolic
BLNK B-cell linker
BLOC1S3 biogenesis of lysosomal organelles complex-1, subunit 3
BLOC1S4 biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
C19ORF25 chromosome 19 open reading frame 25
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta
CHST14 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
COA6 cytochrome c oxidase assembly factor 6
CRYZL1 crystallin, zeta (quinone reductase)-like 1
CTDSPL2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
DHRS4 dehydrogenase/reductase (SDR family) member 4
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8
DKC1 dyskeratosis congenita 1, dyskerin
DPF2 D4, zinc and double PHD fingers family 2
ERH enhancer of rudimentary homolog (Drosophila)
ERMP1 endoplasmic reticulum metallopeptidase 1
FAM162A family with sequence similarity 162, member A
FCHSD2 FCH and double SH3 domains 2
FMN2 formin 2
GEMIN8 gem (nuclear organelle) associated protein 8
GHITM growth hormone inducible transmembrane protein
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GTPBP6 GTP binding protein 6 (putative)
HAT1 histone acetyltransferase 1
HCLS1 hematopoietic cell-specific Lyn substrate 1
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2)
HNRNPL heterogeneous nuclear ribonucleoprotein L
HNRNPR heterogeneous nuclear ribonucleoprotein R
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2
ISLR2 immunoglobulin superfamily containing leucine-rich repeat 2
LAMA5 laminin, alpha 5
LEO1 Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LOC105375028 uncharacterized LOC105375028
LRRC37A5P leucine rich repeat containing 37, member A5, pseudogene
MARCKSL1 MARCKS-like 1
MECP2 methyl CpG binding protein 2
MFAP1 microfibrillar-associated protein 1
MFSD1 major facilitator superfamily domain containing 1
MGST2 microsomal glutathione S-transferase 2
MISP mitotic spindle positioning
MVK mevalonate kinase
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa
NOL8 nucleolar protein 8
NPAT nuclear protein, ataxia-telangiectasia locus
NUMB numb homolog (Drosophila)
NUP210 nucleoporin 210kDa
PABPN1 poly(A) binding protein, nuclear 1
PADI2 peptidyl arginine deiminase, type II
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
PCNT pericentrin
PEG10 paternally expressed 10
PKP3 plakophilin 3
PRCC papillary renal cell carcinoma (translocation-associated)
RAB33B RAB33B, member RAS oncogene family
RCC1 regulator of chromosome condensation 1
RNPS1 RNA binding protein S1, serine-rich domain
RPUSD2 RNA pseudouridylate synthase domain containing 2
SCIN scinderin
SF3B5 splicing factor 3b, subunit 5, 10kDa
SIN3A SIN3 transcription regulator family member A
SRRM1 serine/arginine repetitive matrix 1
SRSF5 serine/arginine-rich splicing factor 5
SSH3 slingshot protein phosphatase 3
STK26 serine/threonine protein kinase 26
STXBP3 syntaxin binding protein 3
SVIL supervillin
SVIP small VCP/p97-interacting protein
TBC1D22A TBC1 domain family, member 22A
TFIP11 tuftelin interacting protein 11
THOC1 THO complex 1
THOC7 THO complex 7
TICRR TOPBP1-interacting checkpoint and replication regulator
TOP1 topoisomerase (DNA) I
TRA2B transformer 2 beta homolog (Drosophila)
TRPT1 tRNA phosphotransferase 1
UBE2G2 ubiquitin-conjugating enzyme E2G 2
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative)
USP11 ubiquitin specific peptidase 11
UTP6 UTP6, small subunit (SSU) processome component, homolog (yeast)
VKORC1L1 vitamin K epoxide reductase complex, subunit 1-like 1
VPS33B vacuolar protein sorting 33 homolog B (yeast)
WDR75 WD repeat domain 75
WDR82 WD repeat domain 82
ZMYM3 zinc finger, MYM-type 3
ZNF326 zinc finger protein 326