NCI-H2591 Gene Set

Dataset Sanger Dependency Map Cancer Cell Line Proteomics
Category proteomics
Type cell line
Description cell line derived from Mesothelioma Unknown (Cell Model Passports, SIDM00101)
External Link https://cellmodelpassports.sanger.ac.uk/passports/SIDM00101
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Genes

197 proteins associated with the cell line NCI-H2591 from the Sanger Dependency Map Cancer Cell Line Proteomics dataset.

Symbol Name
ACACA acetyl-CoA carboxylase alpha
AKAP2 A kinase (PRKA) anchor protein 2
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
AMDHD2 amidohydrolase domain containing 2
ARF4 ADP-ribosylation factor 4
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
BAG3 BCL2-associated athanogene 3
BAZ1A bromodomain adjacent to zinc finger domain, 1A
BRI3 brain protein I3
CCDC115 coiled-coil domain containing 115
CCPG1 cell cycle progression 1
CENPF centromere protein F, 350/400kDa
CLTCL1 clathrin, heavy chain-like 1
CSNK2A2 casein kinase 2, alpha prime polypeptide
CTPS1 CTP synthase 1
CTSH cathepsin H
DCTN5 dynactin 5 (p25)
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DPP7 dipeptidyl-peptidase 7
EEA1 early endosome antigen 1
ENTPD8 ectonucleoside triphosphate diphosphohydrolase 8
FAR1 fatty acyl CoA reductase 1
FLNB filamin B, beta
FLNC filamin C, gamma
FXN frataxin
GNS glucosamine (N-acetyl)-6-sulfatase
HACD3 3-hydroxyacyl-CoA dehydratase 3
HEXA hexosaminidase A (alpha polypeptide)
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
KDSR 3-ketodihydrosphingosine reductase
KRT81 keratin 81, type II
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
MACF1 microtubule-actin crosslinking factor 1
MFGE8 milk fat globule-EGF factor 8 protein
MRS2 MRS2 magnesium transporter
MVB12A multivesicular body subunit 12A
NAP1L5 nucleosome assembly protein 1-like 5
NBR1 neighbor of BRCA1 gene 1
NECAP1 NECAP endocytosis associated 1
NME7 NME/NM23 family member 7
NPC1 Niemann-Pick disease, type C1
NSUN5 NOP2/Sun domain family, member 5
OTULIN OTU deubiquitinase with linear linkage specificity
PDE12 phosphodiesterase 12
PDXK pyridoxal (pyridoxine, vitamin B6) kinase
PGM2 phosphoglucomutase 2
PGRMC2 progesterone receptor membrane component 2
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PLEKHA7 pleckstrin homology domain containing, family A member 7
PML promyelocytic leukemia
PODXL podocalyxin-like
POP4 processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae)
PPIF peptidylprolyl isomerase F
PPME1 protein phosphatase methylesterase 1
PPP1R12BP1 protein phosphatase 1, regulatory subunit 12B pseudogene, Y-linked 1
PRDX6 peroxiredoxin 6
PTP4A1 protein tyrosine phosphatase type IVA, member 1
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN23 protein tyrosine phosphatase, non-receptor type 23
PURA purine-rich element binding protein A
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
PXN paxillin
PYM1 PYM homolog 1, exon junction complex associated factor
RIC8A RIC8 guanine nucleotide exchange factor A
RPP30 ribonuclease P/MRP 30kDa subunit
SAR1A secretion associated, Ras related GTPase 1A
SCAMP2 secretory carrier membrane protein 2
SDCBP syndecan binding protein (syntenin)
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
SFSWAP splicing factor, suppressor of white-apricot family
SLC38A1 solute carrier family 38, member 1
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SQSTM1 sequestosome 1
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
THBS3 thrombospondin 3
TLE4 transducin-like enhancer of split 4
TMEM106B transmembrane protein 106B
TMEM192 transmembrane protein 192
TMEM245 transmembrane protein 245
TMEM43 transmembrane protein 43
TMOD3 tropomodulin 3 (ubiquitous)
TNPO1 transportin 1
TSPAN3 tetraspanin 3
TUBB6 tubulin, beta 6 class V
TXNRD1 thioredoxin reductase 1
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UBTD1 ubiquitin domain containing 1
UIMC1 ubiquitin interaction motif containing 1
USP8 ubiquitin specific peptidase 8
VAC14 Vac14 homolog (S. cerevisiae)
VPS26A vacuolar protein sorting 26 homolog A (S. pombe)
WDR54 WD repeat domain 54
ZNF318 zinc finger protein 318

Symbol Name
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
ACTL6A actin-like 6A
ADNP activity-dependent neuroprotector homeobox
AKAP8 A kinase (PRKA) anchor protein 8
AKAP9 A kinase (PRKA) anchor protein 9
ALKBH5 AlkB family member 5, RNA demethylase
ANAPC2 anaphase promoting complex subunit 2
ARMCX2 armadillo repeat containing, X-linked 2
ASXL3 additional sex combs like transcriptional regulator 3
ATAD2 ATPase family, AAA domain containing 2
ATP13A3 ATPase type 13A3
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BAG1 BCL2-associated athanogene
BCKDK branched chain ketoacid dehydrogenase kinase
BCL7A B-cell CLL/lymphoma 7A
C5ORF22 chromosome 5 open reading frame 22
CCDC126 coiled-coil domain containing 126
CDCA2 cell division cycle associated 2
CHCHD4 coiled-coil-helix-coiled-coil-helix domain containing 4
CHD3 chromodomain helicase DNA binding protein 3
CHERP calcium homeostasis endoplasmic reticulum protein
CMSS1 cms1 ribosomal small subunit homolog (yeast)
COG4 component of oligomeric golgi complex 4
CPSF2 cleavage and polyadenylation specific factor 2, 100kDa
CTDSPL2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
CUL2 cullin 2
DIDO1 death inducer-obliterator 1
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa
ENG endoglin
EPHB4 EPH receptor B4
F2 coagulation factor II (thrombin)
FHIT fragile histidine triad
FHOD1 formin homology 2 domain containing 1
GMPR2 guanosine monophosphate reductase 2
GPATCH8 G patch domain containing 8
GSN gelsolin
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa
GUF1 GUF1 GTPase homolog (S. cerevisiae)
HAUS7 HAUS augmin-like complex, subunit 7
HDHD2 haloacid dehalogenase-like hydrolase domain containing 2
HJURP Holliday junction recognition protein
HNRNPM heterogeneous nuclear ribonucleoprotein M
HSD17B12 hydroxysteroid (17-beta) dehydrogenase 12
IFITM3 interferon induced transmembrane protein 3
INTS9 integrator complex subunit 9
IRS2 insulin receptor substrate 2
KDM1A lysine (K)-specific demethylase 1A
KIAA2013 KIAA2013
KIF22 kinesin family member 22
KNG1 kininogen 1
LRRC4B leucine rich repeat containing 4B
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MANBAL mannosidase, beta A, lysosomal-like
MCAT malonyl CoA:ACP acyltransferase (mitochondrial)
MEF2D myocyte enhancer factor 2D
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MSTO1 misato 1, mitochondrial distribution and morphology regulator
NFX1 nuclear transcription factor, X-box binding 1
NUP50 nucleoporin 50kDa
PCNT pericentrin
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PDXP pyridoxal (pyridoxine, vitamin B6) phosphatase
PEG3 paternally expressed 3
PHC3 polyhomeotic homolog 3 (Drosophila)
PLS1 plastin 1
POLG2 polymerase (DNA directed), gamma 2, accessory subunit
POLR2D polymerase (RNA) II (DNA directed) polypeptide D
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PREP prolyl endopeptidase
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
RBBP6 retinoblastoma binding protein 6
RBFA ribosome binding factor A (putative)
RBM17 RNA binding motif protein 17
RBM25 RNA binding motif protein 25
RBM5 RNA binding motif protein 5
RFFL ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
RPF1 ribosome production factor 1 homolog (S. cerevisiae)
SATB2 SATB homeobox 2
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa
SNRPE small nuclear ribonucleoprotein polypeptide E
SRSF5 serine/arginine-rich splicing factor 5
STRBP spermatid perinuclear RNA binding protein
SUZ12 SUZ12 polycomb repressive complex 2 subunit
TAF6 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
TCEAL4 transcription elongation factor A (SII)-like 4
TDP2 tyrosyl-DNA phosphodiesterase 2
TFIP11 tuftelin interacting protein 11
TH tyrosine hydroxylase
TIMMDC1 translocase of inner mitochondrial membrane domain containing 1
TMEM63A transmembrane protein 63A
TOX4 TOX high mobility group box family member 4
TRMT61A tRNA methyltransferase 61A
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae)
VPS37A vacuolar protein sorting 37 homolog A (S. cerevisiae)
WIPF1 WAS/WASL interacting protein family, member 1
ZBTB7A zinc finger and BTB domain containing 7A