NCI-H28 Gene Set

Dataset Sanger Dependency Map Cancer Cell Line Proteomics
Category proteomics
Type cell line
Description cell line derived from Mesothelioma Metastasis (Cell Model Passports, SIDM00720)
External Link https://cellmodelpassports.sanger.ac.uk/passports/SIDM00720
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Genes

194 proteins associated with the cell line NCI-H28 from the Sanger Dependency Map Cancer Cell Line Proteomics dataset.

Symbol Name
AASS aminoadipate-semialdehyde synthase
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
AKAP12 A kinase (PRKA) anchor protein 12
AMIGO2 adhesion molecule with Ig-like domain 2
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ANXA4 annexin A4
APOL2 apolipoprotein L, 2
ARHGAP29 Rho GTPase activating protein 29
ARL4C ADP-ribosylation factor-like 4C
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
CA12 carbonic anhydrase XII
CDC123 cell division cycle 123
CDC27 cell division cycle 27
CEP55 centrosomal protein 55kDa
CIAO1 cytosolic iron-sulfur assembly component 1
COL12A1 collagen, type XII, alpha 1
COPS7A COP9 signalosome subunit 7A
CRYZ crystallin, zeta (quinone reductase)
DNM2 dynamin 2
DNM3 dynamin 3
DOCK2 dedicator of cytokinesis 2
EFCAB5 EF-hand calcium binding domain 5
ENDOG endonuclease G
FAM162A family with sequence similarity 162, member A
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
FMNL2 formin-like 2
G6PD glucose-6-phosphate dehydrogenase
GBE1 glucan (1,4-alpha-), branching enzyme 1
GCLM glutamate-cysteine ligase, modifier subunit
GDAP2 ganglioside induced differentiation associated protein 2
GLS glutaminase
GLS2 glutaminase 2 (liver, mitochondrial)
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPC1 glypican 1
GPRC5C G protein-coupled receptor, class C, group 5, member C
GTF3C3 general transcription factor IIIC, polypeptide 3, 102kDa
HMOX1 heme oxygenase 1
IQGAP2 IQ motif containing GTPase activating protein 2
ISCA1 iron-sulfur cluster assembly 1
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITM2B integral membrane protein 2B
KPNA6 karyopherin alpha 6 (importin alpha 7)
LOC101928860 uncharacterized LOC101928860
MACF1 microtubule-actin crosslinking factor 1
MAP4 microtubule-associated protein 4
MPG N-methylpurine-DNA glycosylase
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
MYO1E myosin IE
NCS1 neuronal calcium sensor 1
NLN neurolysin (metallopeptidase M3 family)
NOTCH1 notch 1
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NRCAM neuronal cell adhesion molecule
NUBPL nucleotide binding protein-like
NUP43 nucleoporin 43kDa
OSBPL10 oxysterol binding protein-like 10
OSBPL9 oxysterol binding protein-like 9
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PARD3 par-3 family cell polarity regulator
PDCL phosducin-like
PEX6 peroxisomal biogenesis factor 6
PFKP phosphofructokinase, platelet
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
POR P450 (cytochrome) oxidoreductase
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme
PRC1 protein regulator of cytokinesis 1
PSAP prosaposin
PTAR1 protein prenyltransferase alpha subunit repeat containing 1
PTGR1 prostaglandin reductase 1
PTPRJ protein tyrosine phosphatase, receptor type, J
PWP1 PWP1 homolog (S. cerevisiae)
QSER1 glutamine and serine rich 1
RASAL2 RAS protein activator like 2
RBPMS RNA binding protein with multiple splicing
RFFL ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
RIF1 replication timing regulatory factor 1
RNF149 ring finger protein 149
SERINC1 serine incorporator 1
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC35F6 solute carrier family 35, member F6
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SPAG9 sperm associated antigen 9
SPATS2L spermatogenesis associated, serine-rich 2-like
SQSTM1 sequestosome 1
SRXN1 sulfiredoxin 1
SVIL supervillin
TEX264 testis expressed 264
TKT transketolase
TMF1 TATA element modulatory factor 1
TRIOBP TRIO and F-actin binding protein
TRIP12 thyroid hormone receptor interactor 12
TRNT1 tRNA nucleotidyl transferase, CCA-adding, 1
TXNDC9 thioredoxin domain containing 9
UGDH UDP-glucose 6-dehydrogenase
UNC119B unc-119 homolog B (C. elegans)
USP19 ubiquitin specific peptidase 19
USP8 ubiquitin specific peptidase 8
UXS1 UDP-glucuronate decarboxylase 1

Symbol Name
ACOT8 acyl-CoA thioesterase 8
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ALKBH5 AlkB family member 5, RNA demethylase
ARPIN actin-related protein 2/3 complex inhibitor
CAAP1 caspase activity and apoptosis inhibitor 1
CASP8AP2 caspase 8 associated protein 2
CBR1 carbonyl reductase 1
CBR3 carbonyl reductase 3
CCDC97 coiled-coil domain containing 97
CCNA2 cyclin A2
CDCA2 cell division cycle associated 2
CDK11B cyclin-dependent kinase 11B
CDK13 cyclin-dependent kinase 13
CENPC centromere protein C
CEP76 centrosomal protein 76kDa
CLDN12 claudin 12
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CNTNAP1 contactin associated protein 1
COL19A1 collagen, type XIX, alpha 1
DDX59 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59
DHRS7B dehydrogenase/reductase (SDR family) member 7B
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
EFCAB14 EF-hand calcium binding domain 14
EXD2 exonuclease 3'-5' domain containing 2
FBXL20 F-box and leucine-rich repeat protein 20
FBXO22 F-box protein 22
FKBP5 FK506 binding protein 5
FOXP1 forkhead box P1
FRA1D fragile site, aphidicolin type, common, fra(1)(p22)
FYTTD1 forty-two-three domain containing 1
GAA glucosidase, alpha; acid
GLCCI1 glucocorticoid induced 1
HELZ2 helicase with zinc finger 2, transcriptional coactivator
HEXA hexosaminidase A (alpha polypeptide)
HMGN2 high mobility group nucleosomal binding domain 2
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
KDM4A lysine (K)-specific demethylase 4A
KPNA1 karyopherin alpha 1 (importin alpha 5)
L2HGDH L-2-hydroxyglutarate dehydrogenase
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LOC105369341 uncharacterized LOC105369341
LZIC leucine zipper and CTNNBIP1 domain containing
MAN2B1 mannosidase, alpha, class 2B, member 1
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MSL1 male-specific lethal 1 homolog (Drosophila)
MSRB2 methionine sulfoxide reductase B2
MTERF3 mitochondrial transcription termination factor 3
MTIF3 mitochondrial translational initiation factor 3
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NAGA N-acetylgalactosaminidase, alpha-
NDUFC2 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa
NOAZFP nucleolar atypical zinc finger
NSD1 nuclear receptor binding SET domain protein 1
NT5C3A 5'-nucleotidase, cytosolic IIIA
NUCB2 nucleobindin 2
OSTC oligosaccharyltransferase complex subunit (non-catalytic)
PABPN1 poly(A) binding protein, nuclear 1
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PI4K2B phosphatidylinositol 4-kinase type 2 beta
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha
PPT1 palmitoyl-protein thioesterase 1
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit
PRRC2A proline-rich coiled-coil 2A
PTRH1 peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae)
RAB33B RAB33B, member RAS oncogene family
RNGTT RNA guanylyltransferase and 5'-phosphatase
RSRC1 arginine/serine-rich coiled-coil 1
SDF2 stromal cell-derived factor 2
SDR39U1 short chain dehydrogenase/reductase family 39U, member 1
SH3RF1 SH3 domain containing ring finger 1
SIPA1L3 signal-induced proliferation-associated 1 like 3
SKA2 spindle and kinetochore associated complex subunit 2
SLC9A6 solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6
SLN sarcolipin
SRBD1 S1 RNA binding domain 1
SRSF2 serine/arginine-rich splicing factor 2
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TENM3 teneurin transmembrane protein 3
TIMM21 translocase of inner mitochondrial membrane 21 homolog (yeast)
TMEM201 transmembrane protein 201
TRMT5 tRNA methyltransferase 5
URI1 URI1, prefoldin-like chaperone
VAV2 vav 2 guanine nucleotide exchange factor
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae)
WDR54 WD repeat domain 54
ZADH2 zinc binding alcohol dehydrogenase domain containing 2
ZNF512B zinc finger protein 512B