NCI-H345 Gene Set

Dataset Sanger Dependency Map Cancer Cell Line Proteomics
Category proteomics
Type cell line
Description cell line derived from Small Cell Lung Carcinoma Metastasis (Cell Model Passports, SIDM00719)
External Link https://cellmodelpassports.sanger.ac.uk/passports/SIDM00719
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Genes

198 proteins associated with the cell line NCI-H345 from the Sanger Dependency Map Cancer Cell Line Proteomics dataset.

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
AAMP angio-associated, migratory cell protein
ABI2 abl-interactor 2
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila)
ASRGL1 asparaginase like 1
C19ORF47 chromosome 19 open reading frame 47
CBX1 chromobox homolog 1
CCP110 centriolar coiled coil protein 110kDa
CD300E CD300e molecule
CDYL chromodomain protein, Y-like
CENPC centromere protein C
CHAMP1 chromosome alignment maintaining phosphoprotein 1
CHMP3 charged multivesicular body protein 3
CNTRL centriolin
COTL1 coactosin-like F-actin binding protein 1
CWC15 CWC15 spliceosome-associated protein
CXXC1 CXXC finger protein 1
DDAH2 dimethylarginine dimethylaminohydrolase 2
DDX55 DEAD (Asp-Glu-Ala-Asp) box polypeptide 55
DIABLO diablo, IAP-binding mitochondrial protein
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha)
DSN1 DSN1, MIS12 kinetochore complex component
ENO2 enolase 2 (gamma, neuronal)
EPB41L5 erythrocyte membrane protein band 4.1 like 5
FN3K fructosamine 3 kinase
FOXK2 forkhead box K2
FSD1L fibronectin type III and SPRY domain containing 1-like
GCA grancalcin, EF-hand calcium binding protein
GNL1 guanine nucleotide binding protein-like 1
HAGH hydroxyacylglutathione hydrolase
HIRIP3 HIRA interacting protein 3
HMGB3 high mobility group box 3
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3
HNRNPM heterogeneous nuclear ribonucleoprotein M
INPPL1 inositol polyphosphate phosphatase-like 1
KIF5C kinesin family member 5C
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MBD1 methyl-CpG binding domain protein 1
MBD3 methyl-CpG binding domain protein 3
MEAF6 MYST/Esa1-associated factor 6
MPG N-methylpurine-DNA glycosylase
MSH2 mutS homolog 2
MSH6 mutS homolog 6
MTFR1L mitochondrial fission regulator 1-like
MYO7A myosin VIIA
NCAPD3 non-SMC condensin II complex, subunit D3
NCAPH2 non-SMC condensin II complex, subunit H2
NCBP2 nuclear cap binding protein subunit 2, 20kDa
NFIB nuclear factor I/B
NIT1 nitrilase 1
NONO non-POU domain containing, octamer-binding
NSL1 NSL1, MIS12 kinetochore complex component
OR4K3 olfactory receptor, family 4, subfamily K, member 3 (gene/pseudogene)
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PHF6 PHD finger protein 6
PHIP pleckstrin homology domain interacting protein
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
PMF1 polyamine-modulated factor 1
POGZ pogo transposable element with ZNF domain
POLR1A polymerase (RNA) I polypeptide A, 194kDa
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator
PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1
PSIP1 PC4 and SFRS1 interacting protein 1
RAB4B RAB4B, member RAS oncogene family
RAD21 RAD21 homolog (S. pombe)
RBM10 RNA binding motif protein 10
RBM4B RNA binding motif protein 4B
RCOR1 REST corepressor 1
RPRD1A regulation of nuclear pre-mRNA domain containing 1A
RPRD1B regulation of nuclear pre-mRNA domain containing 1B
SCAF4 SR-related CTD-associated factor 4
SCPEP1 serine carboxypeptidase 1
SCRIB scribbled planar cell polarity protein
SFPQ splicing factor proline/glutamine-rich
SH3GLB2 SH3-domain GRB2-like endophilin B2
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
SMC1A structural maintenance of chromosomes 1A
SMC3 structural maintenance of chromosomes 3
SMC6 structural maintenance of chromosomes 6
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1
STRN striatin, calmodulin binding protein
STX17 syntaxin 17
SUPT4H1 suppressor of Ty 4 homolog 1 (S. cerevisiae)
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae)
TAF4 TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa
TARDBP TAR DNA binding protein
TBCB tubulin folding cofactor B
TUBB3 tubulin, beta 3 class III
UBQLN4 ubiquilin 4
ZNF512 zinc finger protein 512

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ABR active BCR-related
ACE angiotensin I converting enzyme
AFP alpha-fetoprotein
ANXA2 annexin A2
AP1M1 adaptor-related protein complex 1, mu 1 subunit
AP3M1 adaptor-related protein complex 3, mu 1 subunit
ARHGAP25 Rho GTPase activating protein 25
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1
ASB2 ankyrin repeat and SOCS box containing 2
C1QBP complement component 1, q subcomponent binding protein
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CAPN5 calpain 5
CCDC51 coiled-coil domain containing 51
CD151 CD151 molecule (Raph blood group)
CEPT1 choline/ethanolamine phosphotransferase 1
CHD3 chromodomain helicase DNA binding protein 3
COL6A3 collagen, type VI, alpha 3
DAD1 defender against cell death 1
DHRS11 dehydrogenase/reductase (SDR family) member 11
EDRF1 erythroid differentiation regulatory factor 1
EHD3 EH-domain containing 3
ETFA electron-transfer-flavoprotein, alpha polypeptide
FRA1C fragile site, aphidicolin type, common, fra(1)(p31.2)
GNL2 guanine nucleotide binding protein-like 2 (nucleolar)
GNL3 guanine nucleotide binding protein-like 3 (nucleolar)
GSTK1 glutathione S-transferase kappa 1
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
IFI16 interferon, gamma-inducible protein 16
IFT46 intraflagellar transport 46
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL1RAP interleukin 1 receptor accessory protein
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
KIAA1522 KIAA1522
KPNA3 karyopherin alpha 3 (importin alpha 4)
KPNA4 karyopherin alpha 4 (importin alpha 3)
LGALS3 lectin, galactoside-binding, soluble, 3
MAK16 MAK16 homolog (S. cerevisiae)
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MOSPD2 motile sperm domain containing 2
MXRA7 matrix-remodelling associated 7
MYBBP1A MYB binding protein (P160) 1a
MYO1C myosin IC
NAT10 N-acetyltransferase 10 (GCN5-related)
NLE1 notchless homolog 1 (Drosophila)
NOC4L nucleolar complex associated 4 homolog (S. cerevisiae)
NOL8 nucleolar protein 8
NOL9 nucleolar protein 9
PLA2G15 phospholipase A2, group XV
POFUT1 protein O-fucosyltransferase 1
PPCDC phosphopantothenoylcysteine decarboxylase
PRMT1 protein arginine methyltransferase 1
PUS1 pseudouridylate synthase 1
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAB7A RAB7A, member RAS oncogene family
RABGGTB Rab geranylgeranyltransferase, beta subunit
RFX5 regulatory factor X, 5 (influences HLA class II expression)
RPL10A ribosomal protein L10a
RPL15 ribosomal protein L15
RPL18 ribosomal protein L18
RPL18A ribosomal protein L18a
RPL23A ribosomal protein L23a
RPL27 ribosomal protein L27
RPL28 ribosomal protein L28
RPL30 ribosomal protein L30
RPL34 ribosomal protein L34
RPL37A ribosomal protein L37a
RPL4 ribosomal protein L4
RPL5 ribosomal protein L5
RPL6 ribosomal protein L6
RPL7 ribosomal protein L7
RPL7A ribosomal protein L7a
RPL9 ribosomal protein L9
RPS13 ribosomal protein S13
RPS16 ribosomal protein S16
RPS26 ribosomal protein S26
RPS9 ribosomal protein S9
RPUSD2 RNA pseudouridylate synthase domain containing 2
RREB1 ras responsive element binding protein 1
RSL1D1 ribosomal L1 domain containing 1
RSPRY1 ring finger and SPRY domain containing 1
SCO1 SCO1 cytochrome c oxidase assembly protein
SH3BP1 SH3-domain binding protein 1
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5
SSR1 signal sequence receptor, alpha
TAGLN2 transgelin 2
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TBRG4 transforming growth factor beta regulator 4
TFRC transferrin receptor
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum)
TYSND1 trypsin domain containing 1
UBA5 ubiquitin-like modifier activating enzyme 5
UBASH3B ubiquitin associated and SH3 domain containing B
WDR12 WD repeat domain 12
ZNF512B zinc finger protein 512B