NCI-H358 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
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Genes

241 genes with high or low expression in NCI-H358 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
GAR1 GAR1 ribonucleoprotein 3.15973
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 2.7336
ATP8B3 ATPase, aminophospholipid transporter, class I, type 8B, member 3 2.35398
PLA2G12A phospholipase A2, group XIIA 2.281
FCRL2 Fc receptor-like 2 2.1683
MAGEA8 melanoma antigen family A8 2.15135
CRIP2 cysteine-rich protein 2 2.087
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 2.03051
MAPK9 mitogen-activated protein kinase 9 1.98931
RARG retinoic acid receptor, gamma 1.97131
CDC73 cell division cycle 73 1.96649
WDR45B WD repeat domain 45B 1.96594
ZNF544 zinc finger protein 544 1.94922
NXF2 nuclear RNA export factor 2 1.92461
ADAM15 ADAM metallopeptidase domain 15 1.92058
MARK3 MAP/microtubule affinity-regulating kinase 3 1.91413
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae) 1.90725
DNM3 dynamin 3 1.90197
PGGT1B protein geranylgeranyltransferase type I, beta subunit 1.89893
MAN2B2 mannosidase, alpha, class 2B, member 2 1.88246
ZFAND1 zinc finger, AN1-type domain 1 1.86586
PIGL phosphatidylinositol glycan anchor biosynthesis, class L 1.81556
SURF2 surfeit 2 1.78838
DHRS2 dehydrogenase/reductase (SDR family) member 2 1.77881
COPS2 COP9 signalosome subunit 2 1.76477
NCBP1 nuclear cap binding protein subunit 1, 80kDa 1.76177
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 1.75326
SCFD1 sec1 family domain containing 1 1.74561
UCHL5 ubiquitin carboxyl-terminal hydrolase L5 1.73085
CTSC cathepsin C 1.70567
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2 1.67628
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 1.67542
UBA6 ubiquitin-like modifier activating enzyme 6 1.66452
SRSF8 serine/arginine-rich splicing factor 8 1.66272
DPY19L4 dpy-19-like 4 (C. elegans) 1.66185
PEX13 peroxisomal biogenesis factor 13 1.65796
MRFAP1L1 Morf4 family associated protein 1-like 1 1.65517
WDR73 WD repeat domain 73 1.65444
ASB7 ankyrin repeat and SOCS box containing 7 1.64565
ICT1 immature colon carcinoma transcript 1 1.64094
DCTD dCMP deaminase 1.63332
CAB39 calcium binding protein 39 1.63206
STK3 serine/threonine kinase 3 1.6305
EMC2 ER membrane protein complex subunit 2 1.62959
ITGB6 integrin, beta 6 1.62032
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2 1.61769
ZNF528 zinc finger protein 528 1.61516
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 1.60584
FUBP3 far upstream element (FUSE) binding protein 3 1.58946
CDC37L1 cell division cycle 37-like 1 1.58765
TMEM156 transmembrane protein 156 1.581
WDR74 WD repeat domain 74 1.57794
RB1CC1 RB1-inducible coiled-coil 1 1.57764
TMEM87A transmembrane protein 87A 1.57283
ZNF227 zinc finger protein 227 1.56962
EDNRA endothelin receptor type A 1.56701
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene 1.55938
TRIP11 thyroid hormone receptor interactor 11 1.55366
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1 1.54998
MB myoglobin 1.54615
E2F5 E2F transcription factor 5, p130-binding 1.5453
BMPR1B bone morphogenetic protein receptor, type IB 1.53958
SYNJ2BP synaptojanin 2 binding protein 1.5362
GBA3 glucosidase, beta, acid 3 (gene/pseudogene) 1.52711
NME7 NME/NM23 family member 7 1.52185
LYPLA2 lysophospholipase II 1.51669
PAX9 paired box 9 1.51383
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 1.50683
ARSF arylsulfatase F 1.49848
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) 1.49451
ZNF614 zinc finger protein 614 1.47124
ZNF200 zinc finger protein 200 1.4704
AP4S1 adaptor-related protein complex 4, sigma 1 subunit 1.46941
PIH1D1 PIH1 domain containing 1 1.46786
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 1.46331
GALK2 galactokinase 2 1.45738
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase 1.44562
ZNF7 zinc finger protein 7 1.43663
SCEL sciellin 1.4361
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) 1.43525
MMP13 matrix metallopeptidase 13 1.42684
SLC30A9 solute carrier family 30 (zinc transporter), member 9 1.42651
GMPR2 guanosine monophosphate reductase 2 1.42621
RNF17 ring finger protein 17 1.42217
NGDN neuroguidin, EIF4E binding protein 1.42109

low expression

Symbol Name Standardized Value
TXNL1 thioredoxin-like 1 -3.39534
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1 -2.95152
AGFG2 ArfGAP with FG repeats 2 -2.61803
PHF14 PHD finger protein 14 -2.52345
TBC1D17 TBC1 domain family, member 17 -2.39323
ECH1 enoyl CoA hydratase 1, peroxisomal -2.33067
WNT6 wingless-type MMTV integration site family, member 6 -2.3024
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) -2.25368
SYNPO synaptopodin -2.24229
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 -2.23719
BAX BCL2-associated X protein -2.21837
DCSTAMP dendrocyte expressed seven transmembrane protein -2.21593
INCENP inner centromere protein antigens 135/155kDa -2.20628
GIPC2 GIPC PDZ domain containing family, member 2 -2.19569
EVL Enah/Vasp-like -2.19094
KLHL29 kelch-like family member 29 -2.17356
ASIC3 acid sensing (proton gated) ion channel 3 -2.1263
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 -2.11738
PPP6R1 protein phosphatase 6, regulatory subunit 1 -2.116
BGLAP bone gamma-carboxyglutamate (gla) protein -2.11507
SESN1 sestrin 1 -2.11425
PNPLA2 patatin-like phospholipase domain containing 2 -2.10854
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled -2.09587
AP2A2 adaptor-related protein complex 2, alpha 2 subunit -2.07542
NEO1 neogenin 1 -2.07392
CASP9 caspase 9, apoptosis-related cysteine peptidase -2.06577
IGFLR1 IGF-like family receptor 1 -2.06044
MYH8 myosin, heavy chain 8, skeletal muscle, perinatal -2.0568
AADAC arylacetamide deacetylase -2.02521
CIC capicua transcriptional repressor -1.993
MYCNOS MYCN opposite strand -1.99091
EPX eosinophil peroxidase -1.99076
TAS2R1 taste receptor, type 2, member 1 -1.97712
FMO4 flavin containing monooxygenase 4 -1.97372
NCAM1 neural cell adhesion molecule 1 -1.95606
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1 -1.95298
ABCA6 ATP-binding cassette, sub-family A (ABC1), member 6 -1.95185
LIMK1 LIM domain kinase 1 -1.95027
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide -1.94772
PRKACA protein kinase, cAMP-dependent, catalytic, alpha -1.94644
BLMH bleomycin hydrolase -1.93297
SH2B3 SH2B adaptor protein 3 -1.92615
IFNAR2 interferon (alpha, beta and omega) receptor 2 -1.89177
SYT5 synaptotagmin V -1.89052
SAA3P serum amyloid A3 pseudogene -1.86175
SPATS2 spermatogenesis associated, serine-rich 2 -1.85934
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa -1.85617
KRT32 keratin 32, type I -1.84745
NXPE3 neurexophilin and PC-esterase domain family, member 3 -1.8439
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase -1.83746
HIST3H3 histone cluster 3, H3 -1.83355
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 -1.82652
OAZ1 ornithine decarboxylase antizyme 1 -1.82
CTIF CBP80/20-dependent translation initiation factor -1.80155
IL9R interleukin 9 receptor -1.80091
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6 -1.79824
KBTBD4 kelch repeat and BTB (POZ) domain containing 4 -1.79759
BBC3 BCL2 binding component 3 -1.78931
EFS embryonal Fyn-associated substrate -1.7811
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -1.77133
MYH7 myosin, heavy chain 7, cardiac muscle, beta -1.76892
CLN3 ceroid-lipofuscinosis, neuronal 3 -1.76243
CKAP5 cytoskeleton associated protein 5 -1.7613
NPFF neuropeptide FF-amide peptide precursor -1.75263
LRRC17 leucine rich repeat containing 17 -1.75205
NCK2 NCK adaptor protein 2 -1.7484
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa -1.74656
TECR trans-2,3-enoyl-CoA reductase -1.744
CCL16 chemokine (C-C motif) ligand 16 -1.74372
PPIA peptidylprolyl isomerase A (cyclophilin A) -1.73797
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 -1.73285
PIAS2 protein inhibitor of activated STAT, 2 -1.7319
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila) -1.72738
IL13 interleukin 13 -1.72116
KCTD7 potassium channel tetramerization domain containing 7 -1.72009
ANKRD26 ankyrin repeat domain 26 -1.71732
CDON cell adhesion associated, oncogene regulated -1.71075
ARR3 arrestin 3, retinal (X-arrestin) -1.70169
FAR2 fatty acyl CoA reductase 2 -1.701
APOM apolipoprotein M -1.69892
CSF1R colony stimulating factor 1 receptor -1.69861
CCDC93 coiled-coil domain containing 93 -1.69461
FLNC filamin C, gamma -1.6873
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) -1.68517
BAMBI BMP and activin membrane-bound inhibitor -1.6846
RANBP3 RAN binding protein 3 -1.68397
GRIA1 glutamate receptor, ionotropic, AMPA 1 -1.68109
RND2 Rho family GTPase 2 -1.67091
MSI1 musashi RNA-binding protein 1 -1.67004
STARD13 StAR-related lipid transfer (START) domain containing 13 -1.6689
MAPT microtubule-associated protein tau -1.66795
GCDH glutaryl-CoA dehydrogenase -1.66631
ATRNL1 attractin-like 1 -1.66341
NIPA2 non imprinted in Prader-Willi/Angelman syndrome 2 -1.65543
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 -1.64908
DEGS1 delta(4)-desaturase, sphingolipid 1 -1.64849
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) -1.64619
COMMD9 COMM domain containing 9 -1.64562
SPN sialophorin -1.63923
ASRGL1 asparaginase like 1 -1.63658
FLT4 fms-related tyrosine kinase 4 -1.63198
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1 -1.62941
LHX5 LIM homeobox 5 -1.62426
LRP3 low density lipoprotein receptor-related protein 3 -1.61523
MAPK8 mitogen-activated protein kinase 8 -1.61474
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 -1.60778
GPR135 G protein-coupled receptor 135 -1.59714
CTNNA2 catenin (cadherin-associated protein), alpha 2 -1.59476
CXCR2 chemokine (C-X-C motif) receptor 2 -1.5908
NCAPD2 non-SMC condensin I complex, subunit D2 -1.58632
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 -1.57914
MEP1B meprin A, beta -1.57604
HCRT hypocretin (orexin) neuropeptide precursor -1.56994
MED16 mediator complex subunit 16 -1.56629
TTC21B tetratricopeptide repeat domain 21B -1.55899
ATXN7L1 ataxin 7-like 1 -1.55608
PRKCQ protein kinase C, theta -1.5515
NR1H3 nuclear receptor subfamily 1, group H, member 3 -1.55027
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 -1.53751
ARF5 ADP-ribosylation factor 5 -1.53417
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 -1.52551
HOXB6 homeobox B6 -1.52027
UQCRC2 ubiquinol-cytochrome c reductase core protein II -1.51884
MEOX1 mesenchyme homeobox 1 -1.51769
TM6SF1 transmembrane 6 superfamily member 1 -1.51364
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated) -1.51298
PIDD1 p53-induced death domain protein 1 -1.51176
SUGP1 SURP and G patch domain containing 1 -1.5048
ADRA2B adrenoceptor alpha 2B -1.50407
RNF167 ring finger protein 167 -1.5037
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding) -1.50162
NUCB2 nucleobindin 2 -1.49606
PIGN phosphatidylinositol glycan anchor biosynthesis, class N -1.48295
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2 -1.48241
HRAS Harvey rat sarcoma viral oncogene homolog -1.481
SPTAN1 spectrin, alpha, non-erythrocytic 1 -1.47497
PEBP1 phosphatidylethanolamine binding protein 1 -1.46967
LMNB2 lamin B2 -1.46833
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) -1.46047
DVL2 dishevelled segment polarity protein 2 -1.45755
ARHGAP17 Rho GTPase activating protein 17 -1.45702
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha -1.45567
TULP3 tubby like protein 3 -1.45522
NLGN4X neuroligin 4, X-linked -1.44608
PEX26 peroxisomal biogenesis factor 26 -1.43824
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) -1.4372
LIN28A lin-28 homolog A (C. elegans) -1.43321
PLA2G5 phospholipase A2, group V -1.43202
KLK15 kallikrein-related peptidase 15 -1.4316
ALG12 ALG12, alpha-1,6-mannosyltransferase -1.42629
IRAK3 interleukin-1 receptor-associated kinase 3 -1.42609
SP4 Sp4 transcription factor -1.42548
CYSLTR1 cysteinyl leukotriene receptor 1 -1.42535
APAF1 apoptotic peptidase activating factor 1 -1.42137
MVD mevalonate (diphospho) decarboxylase -1.42087
LPAR3 lysophosphatidic acid receptor 3 -1.42012