NCI-H446 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
Description disease: carcinoma; small cell lung cancer (lung primary) (Cell Line Ontology, CLO_0008088)
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Genes

489 genes with high or low expression in NCI-H446 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
PPP5C protein phosphatase 5, catalytic subunit 3.60177
LY6H lymphocyte antigen 6 complex, locus H 3.53237
PDE1A phosphodiesterase 1A, calmodulin-dependent 3.38538
NEUROD4 neuronal differentiation 4 3.06917
CDC25C cell division cycle 25C 2.90396
ZFPM2 zinc finger protein, FOG family member 2 2.87211
GPM6A glycoprotein M6A 2.84488
PJA2 praja ring finger 2, E3 ubiquitin protein ligase 2.82781
PHEX phosphate regulating endopeptidase homolog, X-linked 2.81285
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3 2.79082
ETNPPL ethanolamine-phosphate phospho-lyase 2.72751
PPFIA2 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2 2.69761
AGPS alkylglycerone phosphate synthase 2.6846
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 2.66953
B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) 2.6607
TNIK TRAF2 and NCK interacting kinase 2.60686
KIF1B kinesin family member 1B 2.57986
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 2.56568
PAK7 p21 protein (Cdc42/Rac)-activated kinase 7 2.54771
EPHA3 EPH receptor A3 2.54199
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 2.50369
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6 2.49252
TRAPPC3 trafficking protein particle complex 3 2.48249
MINA MYC induced nuclear antigen 2.46605
CTNND2 catenin (cadherin-associated protein), delta 2 2.46438
NUP155 nucleoporin 155kDa 2.42892
AMPH amphiphysin 2.41723
CHEK1 checkpoint kinase 1 2.38359
FAM124B family with sequence similarity 124B 2.36177
ISLR immunoglobulin superfamily containing leucine-rich repeat 2.33206
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 2.30589
CARTPT CART prepropeptide 2.28171
PPP2R2B protein phosphatase 2, regulatory subunit B, beta 2.2697
ADAM22 ADAM metallopeptidase domain 22 2.22937
CRYZL1 crystallin, zeta (quinone reductase)-like 1 2.21548
MRPS27 mitochondrial ribosomal protein S27 2.19156
SNCAIP synuclein, alpha interacting protein 2.18136
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) 2.17592
GLMN glomulin, FKBP associated protein 2.16222
NEO1 neogenin 1 2.15567
BRIX1 BRX1, biogenesis of ribosomes 2.15337
CKAP5 cytoskeleton associated protein 5 2.14025
CHEK2 checkpoint kinase 2 2.13463
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 2.12568
PHTF1 putative homeodomain transcription factor 1 2.12268
SYNGR4 synaptogyrin 4 2.10646
RASSF9 Ras association (RalGDS/AF-6) domain family (N-terminal) member 9 2.08707
CAND1 cullin-associated and neddylation-dissociated 1 2.07635
FEZF2 FEZ family zinc finger 2 2.05504
PRRX1 paired related homeobox 1 2.05045
ALX3 ALX homeobox 3 2.04987
FOCAD focadhesin 2.03816
PROP1 PROP paired-like homeobox 1 2.03495
NTS neurotensin 2.02657
UCK2 uridine-cytidine kinase 2 2.02544
PAGE1 P antigen family, member 1 (prostate associated) 2.01557
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 2.01303
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast) 2.01232
MNS1 meiosis-specific nuclear structural 1 2.00905
CREB1 cAMP responsive element binding protein 1 1.99515
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 1.99513
SPC25 SPC25, NDC80 kinetochore complex component 1.98914
FAR2 fatty acyl CoA reductase 2 1.98731
NFIB nuclear factor I/B 1.97968
AKT3 v-akt murine thymoma viral oncogene homolog 3 1.97849
MAN1C1 mannosidase, alpha, class 1C, member 1 1.97479
PCCB propionyl CoA carboxylase, beta polypeptide 1.97199
CA10 carbonic anhydrase X 1.95633
NFIC nuclear factor I/C (CCAAT-binding transcription factor) 1.94562
RIF1 replication timing regulatory factor 1 1.9428
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) 1.92353
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase 1.92223
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 1.91715
FOXG1 forkhead box G1 1.91558
PRELP proline/arginine-rich end leucine-rich repeat protein 1.9133
HIRIP3 HIRA interacting protein 3 1.91235
NEUROD1 neuronal differentiation 1 1.91074
HLTF helicase-like transcription factor 1.89845
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2 1.89409
TTC33 tetratricopeptide repeat domain 33 1.8901
ATAD2 ATPase family, AAA domain containing 2 1.87884
TRA T cell receptor alpha locus 1.87878
FGF14 fibroblast growth factor 14 1.87761
NTNG1 netrin G1 1.86895
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 1.86819
GAS2 growth arrest-specific 2 1.86771
HIGD1B HIG1 hypoxia inducible domain family, member 1B 1.85105
SH3GL2 SH3-domain GRB2-like 2 1.8472
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2 1.84451
GPR12 G protein-coupled receptor 12 1.84209
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa 1.84007
SOCS2 suppressor of cytokine signaling 2 1.83934
CNTN1 contactin 1 1.83358
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa 1.83348
SEZ6L seizure related 6 homolog (mouse)-like 1.8279
NLGN1 neuroligin 1 1.8272
FRAS1 Fraser extracellular matrix complex subunit 1 1.82395
NOVA1 neuro-oncological ventral antigen 1 1.8232
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 1.82304
TRIM45 tripartite motif containing 45 1.81793
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 1.81431
KIAA0020 KIAA0020 1.80244
CDH5 cadherin 5, type 2 (vascular endothelium) 1.80131
RCL1 RNA terminal phosphate cyclase-like 1 1.79987
CENPI centromere protein I 1.79964
TTLL7 tubulin tyrosine ligase-like family member 7 1.79613
PRKD1 protein kinase D1 1.79351
STXBP5L syntaxin binding protein 5-like 1.78319
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 1.77815
KNTC1 kinetochore associated 1 1.77708
TUBA3C tubulin, alpha 3c 1.77474
TPPP tubulin polymerization promoting protein 1.77179
WRAP73 WD repeat containing, antisense to TP73 1.77178
RANBP1 RAN binding protein 1 1.77115
OXCT1 3-oxoacid CoA transferase 1 1.75919
INCENP inner centromere protein antigens 135/155kDa 1.75522
PLEKHA6 pleckstrin homology domain containing, family A member 6 1.75485
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 1.75157
CAMK4 calcium/calmodulin-dependent protein kinase IV 1.75032
KIF2A kinesin heavy chain member 2A 1.74863
NDST3 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3 1.74779
NKX2-8 NK2 homeobox 8 1.74729
ELAVL2 ELAV like neuron-specific RNA binding protein 2 1.74553
NASP nuclear autoantigenic sperm protein (histone-binding) 1.74385
GCA grancalcin, EF-hand calcium binding protein 1.74361
GAP43 growth associated protein 43 1.73872
IMMT inner membrane protein, mitochondrial 1.73747
CDH12 cadherin 12, type 2 (N-cadherin 2) 1.73414
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 1.73413
SNX7 sorting nexin 7 1.72962
ATP8B3 ATPase, aminophospholipid transporter, class I, type 8B, member 3 1.72577
VRK2 vaccinia related kinase 2 1.72434
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial) 1.7231
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor 1.71669
ADGRB3 adhesion G protein-coupled receptor B3 1.7129
EPHA4 EPH receptor A4 1.71263
NCAPD3 non-SMC condensin II complex, subunit D3 1.71241
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 1.71013
PAX6 paired box 6 1.69963
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 1.69961
PARP2 poly (ADP-ribose) polymerase 2 1.69788
BAZ1A bromodomain adjacent to zinc finger domain, 1A 1.69442
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) 1.69069
GHSR growth hormone secretagogue receptor 1.67939
CSTF2 cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa 1.67635
RAB8B RAB8B, member RAS oncogene family 1.67539
ZNF473 zinc finger protein 473 1.6714
PART1 prostate androgen-regulated transcript 1 (non-protein coding) 1.66955
MYBPC1 myosin binding protein C, slow type 1.66841
TAS2R7 taste receptor, type 2, member 7 1.66726
RPF1 ribosome production factor 1 homolog (S. cerevisiae) 1.66683
FGF12 fibroblast growth factor 12 1.66658
FANCL Fanconi anemia, complementation group L 1.6656
NNT nicotinamide nucleotide transhydrogenase 1.661
MED14 mediator complex subunit 14 1.66067
RAD1 RAD1 checkpoint DNA exonuclease 1.6568
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 1.65568
GPHN gephyrin 1.65499
FABP7 fatty acid binding protein 7, brain 1.65496
SCHIP1 schwannomin interacting protein 1 1.65092
SSX2 synovial sarcoma, X breakpoint 2 1.64532
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D 1.62929
TCP11L1 t-complex 11, testis-specific-like 1 1.62921
FPGT fucose-1-phosphate guanylyltransferase 1.62902
NDST4 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4 1.62585
ICAM5 intercellular adhesion molecule 5, telencephalin 1.62527
MELK maternal embryonic leucine zipper kinase 1.6221
UBE2N ubiquitin-conjugating enzyme E2N 1.62164
EDA ectodysplasin A 1.61803
MAGEB3 melanoma antigen family B3 1.61541
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 1.61242
GRIA4 glutamate receptor, ionotropic, AMPA 4 1.60941
FUZ fuzzy planar cell polarity protein 1.60938
TPX2 TPX2, microtubule-associated 1.60658
CDC7 cell division cycle 7 1.60306
CALM1 calmodulin 1 (phosphorylase kinase, delta) 1.60247
CEP85 centrosomal protein 85kDa 1.60228
NGDN neuroguidin, EIF4E binding protein 1.59993
CRLF1 cytokine receptor-like factor 1 1.59856
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4 1.59688
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 1.59604
CDH7 cadherin 7, type 2 1.59284
LSAMP limbic system-associated membrane protein 1.58931
MRPS22 mitochondrial ribosomal protein S22 1.58765
CNR1 cannabinoid receptor 1 (brain) 1.58452
CLCC1 chloride channel CLIC-like 1 1.56832
COL8A2 collagen, type VIII, alpha 2 1.56824
DLAT dihydrolipoamide S-acetyltransferase 1.56691
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 1.56566
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 1.56556
KIF18A kinesin family member 18A 1.56482
TUBB tubulin, beta class I 1.56343
MAP2 microtubule-associated protein 2 1.56227
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1 1.55733
CXADR coxsackie virus and adenovirus receptor 1.5571
SLN sarcolipin 1.55537
WASF3 WAS protein family, member 3 1.55412
CDH18 cadherin 18, type 2 1.55129
FDXR ferredoxin reductase 1.55124
CORO2B coronin, actin binding protein, 2B 1.54578
NEUROD2 neuronal differentiation 2 1.54532
RIC3 RIC3 acetylcholine receptor chaperone 1.54425
DNAH2 dynein, axonemal, heavy chain 2 1.54356
ZBTB18 zinc finger and BTB domain containing 18 1.54103
PTGFR prostaglandin F receptor (FP) 1.5398
MS4A5 membrane-spanning 4-domains, subfamily A, member 5 1.53609
ARPP21 cAMP-regulated phosphoprotein, 21kDa 1.53461
ZNF343 zinc finger protein 343 1.5313
DCLRE1B DNA cross-link repair 1B 1.52659
GPC3 glypican 3 1.52616
AVP arginine vasopressin 1.52598
GRIA2 glutamate receptor, ionotropic, AMPA 2 1.52514
ERBB4 erb-b2 receptor tyrosine kinase 4 1.52248
LRP1B low density lipoprotein receptor-related protein 1B 1.52106
IPO8 importin 8 1.52088
LRRC40 leucine rich repeat containing 40 1.52086
KDM1A lysine (K)-specific demethylase 1A 1.5203
GDF3 growth differentiation factor 3 1.51716
TGFBR1 transforming growth factor, beta receptor 1 1.51429
DLGAP1 discs, large (Drosophila) homolog-associated protein 1 1.51426
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein 1.51151
PRR3 proline rich 3 1.51148
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2 1.51068
RASL11B RAS-like, family 11, member B 1.50559
CHAF1B chromatin assembly factor 1, subunit B (p60) 1.50488
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 1.50269
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 1.50252
WRB tryptophan rich basic protein 1.50178
APOO apolipoprotein O 1.49818
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 1.49765
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 1.49243
SLITRK3 SLIT and NTRK-like family, member 3 1.49137
E2F3 E2F transcription factor 3 1.48792
COCH cochlin 1.48669
RNASEH2A ribonuclease H2, subunit A 1.48565
RNF8 ring finger protein 8, E3 ubiquitin protein ligase 1.48288
SNAP25 synaptosomal-associated protein, 25kDa 1.48245
RPRD1A regulation of nuclear pre-mRNA domain containing 1A 1.47886
SKIV2L2 superkiller viralicidic activity 2-like 2 (S. cerevisiae) 1.47671
GUF1 GUF1 GTPase homolog (S. cerevisiae) 1.47495
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E 1.47155
HK3 hexokinase 3 (white cell) 1.47073
KCNK7 potassium channel, two pore domain subfamily K, member 7 1.46987
ZDHHC13 zinc finger, DHHC-type containing 13 1.46873
NRXN3 neurexin 3 1.46865
CLSTN2 calsyntenin 2 1.46844
CPLX3 complexin 3 1.46835
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 1.46731
GDAP1 ganglioside induced differentiation associated protein 1 1.46421
HN1 hematological and neurological expressed 1 1.46174
PHF14 PHD finger protein 14 1.45853
MAGEA1 melanoma antigen family A1 1.45788
POLR2G polymerase (RNA) II (DNA directed) polypeptide G 1.45676
RBX1 ring-box 1, E3 ubiquitin protein ligase 1.45502
DGKB diacylglycerol kinase, beta 90kDa 1.45347
KLHL12 kelch-like family member 12 1.45085
POLA2 polymerase (DNA directed), alpha 2, accessory subunit 1.44897
DCTN4 dynactin 4 (p62) 1.4472
POLR2D polymerase (RNA) II (DNA directed) polypeptide D 1.44689
AFF3 AF4/FMR2 family, member 3 1.44575
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 1.44442
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 1.44019
EML4 echinoderm microtubule associated protein like 4 1.44
TDP1 tyrosyl-DNA phosphodiesterase 1 1.43762
KLHDC3 kelch domain containing 3 1.43617
COBLL1 cordon-bleu WH2 repeat protein-like 1 1.43291
EFS embryonal Fyn-associated substrate 1.43253
TIMELESS timeless circadian clock 1.42977
PIH1D1 PIH1 domain containing 1 1.42957
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C 1.42863
LIN7A lin-7 homolog A (C. elegans) 1.42633
HSPA4L heat shock 70kDa protein 4-like 1.42601
OXA1L oxidase (cytochrome c) assembly 1-like 1.42589
RAD54B RAD54 homolog B (S. cerevisiae) 1.42525
TRPC6 transient receptor potential cation channel, subfamily C, member 6 1.4211
CAMKV CaM kinase-like vesicle-associated 1.42009
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3) 1.41981
OR2B2 olfactory receptor, family 2, subfamily B, member 2 1.41955
PAAF1 proteasomal ATPase-associated factor 1 1.41899
MAGEA10 melanoma antigen family A10 1.41815
ZNF112 zinc finger protein 112 1.41792

low expression

Symbol Name Standardized Value
GALT galactose-1-phosphate uridylyltransferase -3.53725
KHNYN KH and NYN domain containing -3.53725
IRF2 interferon regulatory factor 2 -3.53717
DDIT4 DNA-damage-inducible transcript 4 -3.18091
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1 -3.14019
RGS3 regulator of G-protein signaling 3 -3.10875
FKBP15 FK506 binding protein 15, 133kDa -3.10085
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2 -3.09007
HOXB6 homeobox B6 -3.06402
ANXA1 annexin A1 -3.00846
RIN1 Ras and Rab interactor 1 -2.93389
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1 -2.85543
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 -2.79476
ERBB2 erb-b2 receptor tyrosine kinase 2 -2.79351
TGFB1 transforming growth factor, beta 1 -2.6644
CHPF2 chondroitin polymerizing factor 2 -2.56744
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -2.56654
PIGG phosphatidylinositol glycan anchor biosynthesis, class G -2.54117
CASP7 caspase 7, apoptosis-related cysteine peptidase -2.52641
SEC16A SEC16 homolog A (S. cerevisiae) -2.51392
TACO1 translational activator of mitochondrially encoded cytochrome c oxidase I -2.51073
GIMAP5 GTPase, IMAP family member 5 -2.51059
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 -2.48567
MTHFSD methenyltetrahydrofolate synthetase domain containing -2.47373
TAPBPL TAP binding protein-like -2.44257
BICD2 bicaudal D homolog 2 (Drosophila) -2.42307
PIEZO1 piezo-type mechanosensitive ion channel component 1 -2.40855
CUL4A cullin 4A -2.40839
ZNF669 zinc finger protein 669 -2.33059
STYXL1 serine/threonine/tyrosine interacting-like 1 -2.3294
LAMP1 lysosomal-associated membrane protein 1 -2.29117
ZFHX2 zinc finger homeobox 2 -2.2911
LINC00869 long intergenic non-protein coding RNA 869 -2.26635
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -2.25275
TJP2 tight junction protein 2 -2.2285
WWP2 WW domain containing E3 ubiquitin protein ligase 2 -2.22262
TBL2 transducin (beta)-like 2 -2.19852
GDF15 growth differentiation factor 15 -2.18879
SPTLC1 serine palmitoyltransferase, long chain base subunit 1 -2.18063
DOCK6 dedicator of cytokinesis 6 -2.17578
CLN5 ceroid-lipofuscinosis, neuronal 5 -2.17092
TRIM14 tripartite motif containing 14 -2.1679
ACOT9 acyl-CoA thioesterase 9 -2.15853
NAAA N-acylethanolamine acid amidase -2.14064
EDF1 endothelial differentiation-related factor 1 -2.13269
TRAPPC6A trafficking protein particle complex 6A -2.1304
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -2.12631
UBL3 ubiquitin-like 3 -2.11287
ANKRD10 ankyrin repeat domain 10 -2.06673
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 -2.05836
FAM102A family with sequence similarity 102, member A -2.05205
ERCC5 excision repair cross-complementation group 5 -2.02997
STK24 serine/threonine kinase 24 -2.02899
CASP4 caspase 4, apoptosis-related cysteine peptidase -2.01729
HMHB1 histocompatibility (minor) HB-1 -2.01076
JUNB jun B proto-oncogene -2.01062
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase -2.00263
EDC4 enhancer of mRNA decapping 4 -1.99268
NT5C2 5'-nucleotidase, cytosolic II -1.97628
EHD4 EH-domain containing 4 -1.9694
HIST1H3H histone cluster 1, H3h -1.96534
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast) -1.96305
JPH3 junctophilin 3 -1.96019
CNOT4 CCR4-NOT transcription complex, subunit 4 -1.9516
IGLJ3 immunoglobulin lambda joining 3 -1.95046
ZNF652 zinc finger protein 652 -1.94723
ERAP1 endoplasmic reticulum aminopeptidase 1 -1.94013
ORAI3 ORAI calcium release-activated calcium modulator 3 -1.93765
AKAP13 A kinase (PRKA) anchor protein 13 -1.91919
AIM1 absent in melanoma 1 -1.90736
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 -1.9044
SPATS2L spermatogenesis associated, serine-rich 2-like -1.89865
HES1 hes family bHLH transcription factor 1 -1.8894
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) -1.87939
BAMBI BMP and activin membrane-bound inhibitor -1.87841
DEXI Dexi homolog (mouse) -1.8625
SOX13 SRY (sex determining region Y)-box 13 -1.8493
SMOX spermine oxidase -1.84747
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -1.84548
PLCD1 phospholipase C, delta 1 -1.84459
GGTLC1 gamma-glutamyltransferase light chain 1 -1.84327
SPHK1 sphingosine kinase 1 -1.84157
CASP10 caspase 10, apoptosis-related cysteine peptidase -1.83785
ITGA10 integrin, alpha 10 -1.83458
PACS1 phosphofurin acidic cluster sorting protein 1 -1.83136
IGF2R insulin-like growth factor 2 receptor -1.81958
ADGRE5 adhesion G protein-coupled receptor E5 -1.81644
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 -1.8114
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -1.79043
LGALS8 lectin, galactoside-binding, soluble, 8 -1.78677
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 -1.78545
ZXDC ZXD family zinc finger C -1.7839
VEGFA vascular endothelial growth factor A -1.77649
POLD4 polymerase (DNA-directed), delta 4, accessory subunit -1.76845
OLFML2B olfactomedin-like 2B -1.76795
FAM192A family with sequence similarity 192, member A -1.75829
CYHR1 cysteine/histidine-rich 1 -1.75497
ASB6 ankyrin repeat and SOCS box containing 6 -1.75457
DHRS3 dehydrogenase/reductase (SDR family) member 3 -1.75243
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic) -1.74888
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 -1.7464
GSTCD glutathione S-transferase, C-terminal domain containing -1.74072
CHMP2B charged multivesicular body protein 2B -1.74045
CTDNEP1 CTD nuclear envelope phosphatase 1 -1.73345
CSNK2A2 casein kinase 2, alpha prime polypeptide -1.72089
STK11 serine/threonine kinase 11 -1.71955
SSH3 slingshot protein phosphatase 3 -1.71264
SMAD7 SMAD family member 7 -1.70269
ISG20 interferon stimulated exonuclease gene 20kDa -1.69388
MSX2 msh homeobox 2 -1.68955
ELMO3 engulfment and cell motility 3 -1.68624
TOB2 transducer of ERBB2, 2 -1.66756
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6 -1.6584
MON1B MON1 secretory trafficking family member B -1.65796
CDH1 cadherin 1, type 1, E-cadherin (epithelial) -1.65626
COQ4 coenzyme Q4 -1.6524
KRT17 keratin 17, type I -1.64999
VAC14 Vac14 homolog (S. cerevisiae) -1.64453
RBM26 RNA binding motif protein 26 -1.64269
GCHFR GTP cyclohydrolase I feedback regulator -1.63526
UBA7 ubiquitin-like modifier activating enzyme 7 -1.63276
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4 -1.62711
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 -1.62705
SMG6 SMG6 nonsense mediated mRNA decay factor -1.62295
TRIM8 tripartite motif containing 8 -1.6219
PMM2 phosphomannomutase 2 -1.61148
MYD88 myeloid differentiation primary response 88 -1.60705
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box) -1.60044
RBKS ribokinase -1.59799
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1 -1.59788
UBTD1 ubiquitin domain containing 1 -1.59748
NQO1 NAD(P)H dehydrogenase, quinone 1 -1.59568
SAMD4A sterile alpha motif domain containing 4A -1.59521
IFITM3 interferon induced transmembrane protein 3 -1.59502
C1RL complement component 1, r subcomponent-like -1.59418
ANKMY1 ankyrin repeat and MYND domain containing 1 -1.59114
RCAN2 regulator of calcineurin 2 -1.58785
ING1 inhibitor of growth family, member 1 -1.58748
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -1.57977
CYTH4 cytohesin 4 -1.57973
OTUD4 OTU deubiquitinase 4 -1.57839
TAPBP TAP binding protein (tapasin) -1.57608
COASY CoA synthase -1.57001
RANBP10 RAN binding protein 10 -1.56808
PARP12 poly (ADP-ribose) polymerase family, member 12 -1.56459
LAD1 ladinin 1 -1.55786
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -1.55435
SAMD9 sterile alpha motif domain containing 9 -1.55105
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 -1.54923
RAB5A RAB5A, member RAS oncogene family -1.54905
IRF7 interferon regulatory factor 7 -1.54731
RAB11B RAB11B, member RAS oncogene family -1.54488
TMEM115 transmembrane protein 115 -1.54189
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3 -1.53379
NBEAL2 neurobeachin-like 2 -1.52977
LASP1 LIM and SH3 protein 1 -1.52505
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 -1.52288
TRIM13 tripartite motif containing 13 -1.51759
VGLL4 vestigial-like family member 4 -1.51688
AGO4 argonaute RISC catalytic component 4 -1.51181
IFITM1 interferon induced transmembrane protein 1 -1.51088
NCOA4 nuclear receptor coactivator 4 -1.51035
IER2 immediate early response 2 -1.50926
G0S2 G0/G1 switch 2 -1.50128
MLPH melanophilin -1.50115
HLA-C major histocompatibility complex, class I, C -1.50083
C5 complement component 5 -1.50021
PHF11 PHD finger protein 11 -1.50017
CNTNAP2 contactin associated protein-like 2 -1.49897
PLEC plectin -1.4986
PTGES prostaglandin E synthase -1.49759
PPP1R13L protein phosphatase 1, regulatory subunit 13 like -1.49445
NID1 nidogen 1 -1.49101
TNS2 tensin 2 -1.48967
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -1.48897
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11 -1.4858
GRK4 G protein-coupled receptor kinase 4 -1.48441
MAP3K14 mitogen-activated protein kinase kinase kinase 14 -1.48421
HLA-B major histocompatibility complex, class I, B -1.48387
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 -1.48381
SEC24C SEC24 family member C -1.47699
MICA MHC class I polypeptide-related sequence A -1.47688
TMBIM1 transmembrane BAX inhibitor motif containing 1 -1.4765
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae) -1.47617
TJP3 tight junction protein 3 -1.47492
ACAA1 acetyl-CoA acyltransferase 1 -1.4669
APRT adenine phosphoribosyltransferase -1.46138
TLR4 toll-like receptor 4 -1.46124
FBXW4 F-box and WD repeat domain containing 4 -1.46027
FRAT1 frequently rearranged in advanced T-cell lymphomas 1 -1.4576
MAN2B2 mannosidase, alpha, class 2B, member 2 -1.45677
LY6G5C lymphocyte antigen 6 complex, locus G5C -1.45602
SLC12A8 solute carrier family 12, member 8 -1.45513
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 -1.45508
FYCO1 FYVE and coiled-coil domain containing 1 -1.45392
FOXO4 forkhead box O4 -1.446
NSD1 nuclear receptor binding SET domain protein 1 -1.43875
RIN3 Ras and Rab interactor 3 -1.43802
GPR137B G protein-coupled receptor 137B -1.4368
NKX3-1 NK3 homeobox 1 -1.43315
CTSD cathepsin D -1.43118
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1 -1.42993
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 -1.42221
IRF9 interferon regulatory factor 9 -1.42206
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12 -1.42158
PEX11A peroxisomal biogenesis factor 11 alpha -1.4209
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin) -1.42
DOK5 docking protein 5 -1.41771