NCI-H446 Gene Set

Dataset Sanger Dependency Map Cancer Cell Line Proteomics
Category proteomics
Type cell line
External Link https://cellmodelpassports.sanger.ac.uk/passports/SIDM00965
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Genes

196 proteins associated with the cell line NCI-H446 from the Sanger Dependency Map Cancer Cell Line Proteomics dataset.

Symbol Name
AMACR alpha-methylacyl-CoA racemase
ANKLE1 ankyrin repeat and LEM domain containing 1
BRD2 bromodomain containing 2
BRD4 bromodomain containing 4
C19ORF53 chromosome 19 open reading frame 53
CAAP1 caspase activity and apoptosis inhibitor 1
CAND1 cullin-associated and neddylation-dissociated 1
CDK4 cyclin-dependent kinase 4
CFL2 cofilin 2 (muscle)
CHAF1A chromatin assembly factor 1, subunit A (p150)
CHD1 chromodomain helicase DNA binding protein 1
CHD7 chromodomain helicase DNA binding protein 7
CHEK2 checkpoint kinase 2
CIRBP cold inducible RNA binding protein
CLDN12 claudin 12
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa
CRYBG3 beta-gamma crystallin domain containing 3
CSPG4 chondroitin sulfate proteoglycan 4
CUL5 cullin 5
CWF19L2 CWF19-like 2, cell cycle control (S. pombe)
CXADR coxsackie virus and adenovirus receptor
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1
DERL1 derlin 1
DERL2 derlin 2
DHX36 DEAH (Asp-Glu-Ala-His) box polypeptide 36
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
DPYSL3 dihydropyrimidinase-like 3
EHBP1 EH domain binding protein 1
EIF2B4 eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa
ELAVL2 ELAV like neuron-specific RNA binding protein 2
EPHA4 EPH receptor A4
FTSJ1 FtsJ RNA methyltransferase homolog 1 (E. coli)
FZD7 frizzled class receptor 7
GAP43 growth associated protein 43
GEMIN2 gem (nuclear organelle) associated protein 2
GET4 golgi to ER traffic protein 4 homolog (S. cerevisiae)
GLTP glycolipid transfer protein
GMPS guanine monphosphate synthase
HK2 hexokinase 2
HMGN2 high mobility group nucleosomal binding domain 2
HSPG2 heparan sulfate proteoglycan 2
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
INPP5F inositol polyphosphate-5-phosphatase F
IPO9 importin 9
IQGAP3 IQ motif containing GTPase activating protein 3
ISLR immunoglobulin superfamily containing leucine-rich repeat
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KLC1 kinesin light chain 1
KNG1 kininogen 1
KRT14 keratin 14, type I
LINC00919 long intergenic non-protein coding RNA 919
LOC105375686 uncharacterized LOC105375686
LOC105378759 uncharacterized LOC105378759
MAP2K2 mitogen-activated protein kinase kinase 2
MASTL microtubule associated serine/threonine kinase-like
MED25 mediator complex subunit 25
MOB2 MOB kinase activator 2
MTA1 metastasis associated 1
MYO7A myosin VIIA
NFIA nuclear factor I/A
NFIB nuclear factor I/B
NFXL1 nuclear transcription factor, X-box binding-like 1
NOSIP nitric oxide synthase interacting protein
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae)
NSUN5 NOP2/Sun domain family, member 5
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PDCD2L programmed cell death 2-like
PELO pelota homolog (Drosophila)
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PQBP1 polyglutamine binding protein 1
PRRC2A proline-rich coiled-coil 2A
RBM15B RNA binding motif protein 15B
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPS19P3 ribosomal protein S19 pseudogene 3
RTN4RL2 reticulon 4 receptor-like 2
SAMD4B sterile alpha motif domain containing 4B
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SOGA1 suppressor of glucose, autophagy associated 1
SORBS3 sorbin and SH3 domain containing 3
SSRP1 structure specific recognition protein 1
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae)
SYMPK symplekin
TNIK TRAF2 and NCK interacting kinase
TRAPPC3 trafficking protein particle complex 3
TRIM24 tripartite motif containing 24
TRIT1 tRNA isopentenyltransferase 1
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
USP21 ubiquitin specific peptidase 21
USP48 ubiquitin specific peptidase 48
UTP6 UTP6, small subunit (SSU) processome component, homolog (yeast)
VRK1 vaccinia related kinase 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
YEATS2 YEATS domain containing 2
ZNF346 zinc finger protein 346
ZNF768 zinc finger protein 768
ZNRF2 zinc and ring finger 2, E3 ubiquitin protein ligase

Symbol Name
ACSS3 acyl-CoA synthetase short-chain family member 3
AGTRAP angiotensin II receptor-associated protein
ALDH1L2 aldehyde dehydrogenase 1 family, member L2
APOOL apolipoprotein O-like
ARL6IP6 ADP-ribosylation factor-like 6 interacting protein 6
ARL8B ADP-ribosylation factor-like 8B
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa
ASF1B anti-silencing function 1B histone chaperone
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide
BCL2L13 BCL2-like 13 (apoptosis facilitator)
BIRC6 baculoviral IAP repeat containing 6
CA2 carbonic anhydrase II
CADM4 cell adhesion molecule 4
CASP2 caspase 2, apoptosis-related cysteine peptidase
CD109 CD109 molecule
CNOT11 CCR4-NOT transcription complex, subunit 11
COA6 cytochrome c oxidase assembly factor 6
COL10A1 collagen, type X, alpha 1
COMMD8 COMM domain containing 8
COX19 COX19 cytochrome c oxidase assembly factor
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa
DLD dihydrolipoamide dehydrogenase
ECE1 endothelin converting enzyme 1
EFCAB5 EF-hand calcium binding domain 5
EGLN1 egl-9 family hypoxia-inducible factor 1
EHBP1L1 EH domain binding protein 1-like 1
EPM2AIP1 EPM2A (laforin) interacting protein 1
ERCC6L excision repair cross-complementation group 6-like
ERLIN2 ER lipid raft associated 2
FUCA2 fucosidase, alpha-L- 2, plasma
FXN frataxin
GCC2 GRIP and coiled-coil domain containing 2
GFAP glial fibrillary acidic protein
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GLB1 galactosidase, beta 1
GLE1 GLE1 RNA export mediator
GLUD1 glutamate dehydrogenase 1
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial
HEATR5B HEAT repeat containing 5B
HPSE heparanase
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha
IDH3B isocitrate dehydrogenase 3 (NAD+) beta
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
ISCA2 iron-sulfur cluster assembly 2
ITSN2 intersectin 2
KDSR 3-ketodihydrosphingosine reductase
LAMP1 lysosomal-associated membrane protein 1
LAMP2 lysosomal-associated membrane protein 2
LDB1 LIM domain binding 1
LOC105375357 uncharacterized LOC105375357
LOC105375484 uncharacterized LOC105375484
MECR mitochondrial trans-2-enoyl-CoA reductase
MIPEP mitochondrial intermediate peptidase
MRPL2 mitochondrial ribosomal protein L2
MSL1 male-specific lethal 1 homolog (Drosophila)
MXRA7 matrix-remodelling associated 7
NCOR1 nuclear receptor corepressor 1
NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa
NFYA nuclear transcription factor Y, alpha
OBSL1 obscurin-like 1
OR4A7P olfactory receptor, family 4, subfamily A, member 7 pseudogene
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic)
PARD3 par-3 family cell polarity regulator
PARN poly(A)-specific ribonuclease
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1
PDHB pyruvate dehydrogenase (lipoamide) beta
POLR2D polymerase (RNA) II (DNA directed) polypeptide D
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1)
PPIE peptidylprolyl isomerase E (cyclophilin E)
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PRDX3 peroxiredoxin 3
RBBP6 retinoblastoma binding protein 6
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF167 ring finger protein 167
RNF220 ring finger protein 220
RRAS related RAS viral (r-ras) oncogene homolog
RSRC2 arginine/serine-rich coiled-coil 2
S100A10 S100 calcium binding protein A10
S100A11 S100 calcium binding protein A11
SAMHD1 SAM domain and HD domain 1
SAMM50 SAMM50 sorting and assembly machinery component
SMIM20 small integral membrane protein 20
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae)
STX10 syntaxin 10
SUCLG1 succinate-CoA ligase, alpha subunit
TCAF1 TRPM8 channel-associated factor 1
TIMM21 translocase of inner mitochondrial membrane 21 homolog (yeast)
TTC33 tetratricopeptide repeat domain 33
VTI1B vesicle transport through interaction with t-SNAREs 1B
WAC WW domain containing adaptor with coiled-coil
WDR26 WD repeat domain 26
ZC3HAV1 zinc finger CCCH-type, antiviral 1
ZNF644 zinc finger protein 644
ZNRF1 zinc and ring finger 1, E3 ubiquitin protein ligase