NCI-H508 Gene Set

Dataset Sanger Dependency Map Cancer Cell Line Proteomics
Category proteomics
Type cell line
Description cell line derived from Colorectal Carcinoma Metastasis (Cell Model Passports, SIDM00777)
External Link https://cellmodelpassports.sanger.ac.uk/passports/SIDM00777
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Genes

198 proteins associated with the cell line NCI-H508 from the Sanger Dependency Map Cancer Cell Line Proteomics dataset.

Symbol Name
ABHD14B abhydrolase domain containing 14B
AHCY adenosylhomocysteinase
AKAP1 A kinase (PRKA) anchor protein 1
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ALG5 ALG5, dolichyl-phosphate beta-glucosyltransferase
ANXA4 annexin A4
APTX aprataxin
ARFIP1 ADP-ribosylation factor interacting protein 1
ARHGAP26 Rho GTPase activating protein 26
ARHGAP5 Rho GTPase activating protein 5
ASL argininosuccinate lyase
BCCIP BRCA2 and CDKN1A interacting protein
CEP104 centrosomal protein 104kDa
CHMP3 charged multivesicular body protein 3
CHMP4B charged multivesicular body protein 4B
CLN5 ceroid-lipofuscinosis, neuronal 5
CRYL1 crystallin, lambda 1
CSTB cystatin B (stefin B)
DDAH1 dimethylarginine dimethylaminohydrolase 1
DHRS11 dehydrogenase/reductase (SDR family) member 11
DIAPH3 diaphanous-related formin 3
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2
DNPEP aspartyl aminopeptidase
EML4 echinoderm microtubule associated protein like 4
FABP1 fatty acid binding protein 1, liver
FTH1 ferritin, heavy polypeptide 1
FUCA2 fucosidase, alpha-L- 2, plasma
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
GGCT gamma-glutamylcyclotransferase
GLYCTK glycerate kinase
GMDS GDP-mannose 4,6-dehydratase
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
HSPH1 heat shock 105kDa/110kDa protein 1
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KPNA3 karyopherin alpha 3 (importin alpha 4)
LGALS3 lectin, galactoside-binding, soluble, 3
LGALS4 lectin, galactoside-binding, soluble, 4
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
MAP7 microtubule-associated protein 7
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha)
MIPEP mitochondrial intermediate peptidase
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MRPL14 mitochondrial ribosomal protein L14
MRPS31 mitochondrial ribosomal protein S31
MRPS35 mitochondrial ribosomal protein S35
MRPS7 mitochondrial ribosomal protein S7
MUC12 mucin 12, cell surface associated
NDUFA3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa
NME2 NME/NM23 nucleoside diphosphate kinase 2
NOTCH4 notch 4
NUBPL nucleotide binding protein-like
PCCA propionyl CoA carboxylase, alpha polypeptide
PCCB propionyl CoA carboxylase, beta polypeptide
PCYT1A phosphate cytidylyltransferase 1, choline, alpha
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PNPO pyridoxamine 5'-phosphate oxidase
POF1B premature ovarian failure, 1B
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B
PREP prolyl endopeptidase
PRTFDC1 phosphoribosyl transferase domain containing 1
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
PSMG3 proteasome (prosome, macropain) assembly chaperone 3
PTBP3 polypyrimidine tract binding protein 3
PTCD3 pentatricopeptide repeat domain 3
RPL35A ribosomal protein L35a
RPP30 ribonuclease P/MRP 30kDa subunit
RPS11 ribosomal protein S11
RPS27 ribosomal protein S27
SBDS Shwachman-Bodian-Diamond syndrome
SCFD1 sec1 family domain containing 1
SCLY selenocysteine lyase
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SH3BGRL2 SH3 domain binding glutamate-rich protein like 2
SIAE sialic acid acetylesterase
SIDT1 SID1 transmembrane family, member 1
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SMAP1 small ArfGAP 1
SORD sorbitol dehydrogenase
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
SRI sorcin
SRPK1 SRSF protein kinase 1
STK24 serine/threonine kinase 24
SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit
SUCLG1 succinate-CoA ligase, alpha subunit
SUGT1 SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)
TAS2R13 taste receptor, type 2, member 13
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TPP2 tripeptidyl peptidase II
TST thiosulfate sulfurtransferase (rhodanese)
TTC38 tetratricopeptide repeat domain 38
UBE2D2 ubiquitin-conjugating enzyme E2D 2
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
UFM1 ubiquitin-fold modifier 1
VPS25 vacuolar protein sorting 25 homolog (S. cerevisiae)
VWA8 von Willebrand factor A domain containing 8
WDR55 WD repeat domain 55
ZWINT ZW10 interacting kinetochore protein

Symbol Name
ACTG1P22 actin gamma 1 pseudogene 22
AHCYL1 adenosylhomocysteinase-like 1
AIDA axin interactor, dorsalization associated
ALPK3 alpha-kinase 3
AMPH amphiphysin
ARSB arylsulfatase B
ATAD2 ATPase family, AAA domain containing 2
ATL3 atlastin GTPase 3
BAK1 BCL2-antagonist/killer 1
C17ORF49 chromosome 17 open reading frame 49
C19ORF47 chromosome 19 open reading frame 47
C1QTNF6 C1q and tumor necrosis factor related protein 6
C2CD2L C2CD2-like
CA12 carbonic anhydrase XII
CALCOCO1 calcium binding and coiled-coil domain 1
CAV1 caveolin 1, caveolae protein, 22kDa
CCDC85C coiled-coil domain containing 85C
CDC20 cell division cycle 20
CDCA2 cell division cycle associated 2
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDH26 cadherin 26
CEP170 centrosomal protein 170kDa
CRAT carnitine O-acetyltransferase
DBN1 drebrin 1
DNLZ DNL-type zinc finger
DRD2 dopamine receptor D2
ECI2 enoyl-CoA delta isomerase 2
EPS8L1 EPS8-like 1
FGFRL1 fibroblast growth factor receptor-like 1
FKBP14 FK506 binding protein 14, 22 kDa
FLNA filamin A, alpha
GIMAP7 GTPase, IMAP family member 7
GLMP glycosylated lysosomal membrane protein
GOLT1B golgi transport 1B
HK1 hexokinase 1
HOMER3 homer scaffolding protein 3
KANK2 KN motif and ankyrin repeat domains 2
KBTBD2 kelch repeat and BTB (POZ) domain containing 2
LAMB3 laminin, beta 3
LENG1 leukocyte receptor cluster (LRC) member 1
LENG9 leukocyte receptor cluster (LRC) member 9
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS8 lectin, galactoside-binding, soluble, 8
LIMCH1 LIM and calponin homology domains 1
LRIF1 ligand dependent nuclear receptor interacting factor 1
LTN1 listerin E3 ubiquitin protein ligase 1
LYSMD2 LysM, putative peptidoglycan-binding, domain containing 2
MACROD1 MACRO domain containing 1
MAGEA4 melanoma antigen family A4
MAN1B1 mannosidase, alpha, class 1B, member 1
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1
MAP7D1 MAP7 domain containing 1
MCL1 myeloid cell leukemia 1
MKRN2 makorin ring finger protein 2
MOV10 Mov10 RISC complex RNA helicase
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NOTCH2 notch 2
OR4E2 olfactory receptor, family 4, subfamily E, member 2
OSBPL8 oxysterol binding protein-like 8
OXCT1 3-oxoacid CoA transferase 1
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PI4K2B phosphatidylinositol 4-kinase type 2 beta
PITX1 paired-like homeodomain 1
POGZ pogo transposable element with ZNF domain
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2
PPP1R18 protein phosphatase 1, regulatory subunit 18
PPTC7 PTC7 protein phosphatase homolog (S. cerevisiae)
PRAF2 PRA1 domain family, member 2
PRR3 proline rich 3
PTPRJ protein tyrosine phosphatase, receptor type, J
RAB5B RAB5B, member RAS oncogene family
RAVER2 ribonucleoprotein, PTB-binding 2
RBM12B RNA binding motif protein 12B
RBM38 RNA binding motif protein 38
RDX radixin
RGS10 regulator of G-protein signaling 10
RHOF ras homolog family member F (in filopodia)
RRAD Ras-related associated with diabetes
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SH3BP4 SH3-domain binding protein 4
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC38A1 solute carrier family 38, member 1
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
SOAT1 sterol O-acyltransferase 1
SOWAHC sosondowah ankyrin repeat domain family member C
TARBP2 TAR (HIV-1) RNA binding protein 2
TGS1 trimethylguanosine synthase 1
TMEM245 transmembrane protein 245
TXNDC15 thioredoxin domain containing 15
UBE2J1 ubiquitin-conjugating enzyme E2, J1
VAC14 Vac14 homolog (S. cerevisiae)
VIP vasoactive intestinal peptide
VMA21 VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
YTHDC1 YTH domain containing 1