NCI-H740 Gene Set

Dataset Sanger Dependency Map Cancer Cell Line Proteomics
Category proteomics
Type cell line
Description cell line derived from Small Cell Lung Carcinoma Metastasis (Cell Model Passports, SIDM01118)
External Link https://cellmodelpassports.sanger.ac.uk/passports/SIDM01118
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Genes

199 proteins associated with the cell line NCI-H740 from the Sanger Dependency Map Cancer Cell Line Proteomics dataset.

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ACTL6A actin-like 6A
ADD2 adducin 2 (beta)
ADNP activity-dependent neuroprotector homeobox
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
BUD31 BUD31 homolog (S. cerevisiae)
CARHSP1 calcium regulated heat stable protein 1, 24kDa
CBX1 chromobox homolog 1
CC2D1A coiled-coil and C2 domain containing 1A
CCDC134 coiled-coil domain containing 134
CCP110 centriolar coiled coil protein 110kDa
CD81 CD81 molecule
CDYL chromodomain protein, Y-like
CEP131 centrosomal protein 131kDa
CHAMP1 chromosome alignment maintaining phosphoprotein 1
COPS7B COP9 signalosome subunit 7B
CRTC2 CREB regulated transcription coactivator 2
DBR1 debranching RNA lariats 1
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
DLG3 discs, large homolog 3 (Drosophila)
DPYSL3 dihydropyrimidinase-like 3
DPYSL4 dihydropyrimidinase-like 4
DYNLL2 dynein, light chain, LC8-type 2
ECT2 epithelial cell transforming 2
ENO2 enolase 2 (gamma, neuronal)
FN3KRP fructosamine 3 kinase related protein
GDE1 glycerophosphodiester phosphodiesterase 1
GDI1 GDP dissociation inhibitor 1
GLCE glucuronic acid epimerase
GNAS GNAS complex locus
GSK3B glycogen synthase kinase 3 beta
HEBP2 heme binding protein 2
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMGN2 high mobility group nucleosomal binding domain 2
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0
HP1BP3 heterochromatin protein 1, binding protein 3
HPSE heparanase
HTATSF1 HIV-1 Tat specific factor 1
HYOU1 hypoxia up-regulated 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
INPPL1 inositol polyphosphate phosphatase-like 1
KIF5C kinesin family member 5C
KPNA1 karyopherin alpha 1 (importin alpha 5)
KRT20 keratin 20, type I
LMNB1 lamin B1
LOC442389 interferon induced transmembrane protein pseudogene
LUC7L3 LUC7-like 3 (S. cerevisiae)
MAP1B microtubule-associated protein 1B
MAPK13 mitogen-activated protein kinase 13
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MBTD1 mbt domain containing 1
MESTP4 mesoderm specific transcript pseudogene 4
MFSD1 major facilitator superfamily domain containing 1
MPLKIP M-phase specific PLK1 interacting protein
MSH2 mutS homolog 2
MSH6 mutS homolog 6
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma
NCAPD3 non-SMC condensin II complex, subunit D3
NCAPH2 non-SMC condensin II complex, subunit H2
NIPBL Nipped-B homolog (Drosophila)
NRGN neurogranin (protein kinase C substrate, RC3)
NUSAP1 nucleolar and spindle associated protein 1
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PHIP pleckstrin homology domain interacting protein
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator
PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1
PRSS2 protease, serine, 2 (trypsin 2)
PSIP1 PC4 and SFRS1 interacting protein 1
RBM6 RNA binding motif protein 6
RBP1 retinol binding protein 1, cellular
RPRD1A regulation of nuclear pre-mRNA domain containing 1A
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SFXN2 sideroflexin 2
SH3GLB2 SH3-domain GRB2-like endophilin B2
SMAD4 SMAD family member 4
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
SRSF4 serine/arginine-rich splicing factor 4
STK39 serine threonine kinase 39
STRN striatin, calmodulin binding protein
SUMO2 small ubiquitin-like modifier 2
TAGLN3 transgelin 3
TARDBP TAR DNA binding protein
TBCB tubulin folding cofactor B
TMPO thymopoietin
TSN translin
TSSC4 tumor suppressing subtransferable candidate 4
TTC9 tetratricopeptide repeat domain 9
TUBB2B tubulin, beta 2B class IIb
TUBB3 tubulin, beta 3 class III
UBTF upstream binding transcription factor, RNA polymerase I
UBXN7 UBX domain protein 7
USP21 ubiquitin specific peptidase 21
ZFP91 ZFP91 zinc finger protein
ZNF292 zinc finger protein 292
ZNF428 zinc finger protein 428
ZNF512 zinc finger protein 512
ZNHIT2 zinc finger, HIT-type containing 2

Symbol Name
ACOT9 acyl-CoA thioesterase 9
ALDH18A1 aldehyde dehydrogenase 18 family, member A1
ANK1 ankyrin 1, erythrocytic
ARL1 ADP-ribosylation factor-like 1
BMS1 BMS1 ribosome biogenesis factor
BOP1 block of proliferation 1
C11ORF68 chromosome 11 open reading frame 68
C1ORF131 chromosome 1 open reading frame 131
C1QBP complement component 1, q subcomponent binding protein
CCDC51 coiled-coil domain containing 51
CHURC1 churchill domain containing 1
COA7 cytochrome c oxidase assembly factor 7 (putative)
CUL4A cullin 4A
CYHR1 cysteine/histidine-rich 1
D2HGDH D-2-hydroxyglutarate dehydrogenase
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
EIF1AX eukaryotic translation initiation factor 1A, X-linked
ELAC2 elaC ribonuclease Z 2
ETFA electron-transfer-flavoprotein, alpha polypeptide
ETFB electron-transfer-flavoprotein, beta polypeptide
EXOSC7 exosome component 7
FAM184B family with sequence similarity 184, member B
FLJ31662 uncharacterized LOC440594
GAR1 GAR1 ribonucleoprotein
GLUD1 glutamate dehydrogenase 1
GNL3 guanine nucleotide binding protein-like 3 (nucleolar)
GRPEL1 GrpE-like 1, mitochondrial (E. coli)
HAUS3 HAUS augmin-like complex, subunit 3
HCLS1 hematopoietic cell-specific Lyn substrate 1
HEATR1 HEAT repeat containing 1
HEBP1 heme binding protein 1
IMP3 IMP3, U3 small nucleolar ribonucleoprotein
INTS4 integrator complex subunit 4
IPO4 importin 4
IRF8 interferon regulatory factor 8
JAK1 Janus kinase 1
KIAA1522 KIAA1522
LETM1 leucine zipper-EF-hand containing transmembrane protein 1
LYAR Ly1 antibody reactive
MMP27 matrix metallopeptidase 27
MRPS12 mitochondrial ribosomal protein S12
MRPS14 mitochondrial ribosomal protein S14
MRPS17 mitochondrial ribosomal protein S17
MRPS27 mitochondrial ribosomal protein S27
MRPS31 mitochondrial ribosomal protein S31
MRPS34 mitochondrial ribosomal protein S34
MRPS35 mitochondrial ribosomal protein S35
MRPS6 mitochondrial ribosomal protein S6
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
MTRF1L mitochondrial translational release factor 1-like
MYBBP1A MYB binding protein (P160) 1a
NAT10 N-acetyltransferase 10 (GCN5-related)
NDC1 NDC1 transmembrane nucleoporin
NGDN neuroguidin, EIF4E binding protein
NIFK nucleolar protein interacting with the FHA domain of MKI67
NOL6 nucleolar protein 6 (RNA-associated)
NOL7 nucleolar protein 7, 27kDa
NOLC1 nucleolar and coiled-body phosphoprotein 1
NOP14 NOP14 nucleolar protein
NOP16 NOP16 nucleolar protein
NOP2 NOP2 nucleolar protein
NPM3 nucleophosmin/nucleoplasmin 3
NTPCR nucleoside-triphosphatase, cancer-related
OCIAD1 OCIA domain containing 1
OXA1L oxidase (cytochrome c) assembly 1-like
PAH phenylalanine hydroxylase
PDCD11 programmed cell death 11
PEPD peptidase D
PES1 pescadillo ribosomal biogenesis factor 1
PI4KB phosphatidylinositol 4-kinase, catalytic, beta
PLPP6 phospholipid phosphatase 6
PNO1 partner of NOB1 homolog (S. cerevisiae)
POLR1E polymerase (RNA) I polypeptide E, 53kDa
PYCR1 pyrroline-5-carboxylate reductase 1
RDH13 retinol dehydrogenase 13 (all-trans/9-cis)
RPS19P3 ribosomal protein S19 pseudogene 3
RRP1 ribosomal RNA processing 1
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
RRP7A ribosomal RNA processing 7 homolog A (S. cerevisiae)
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
RSL1D1 ribosomal L1 domain containing 1
SCO1 SCO1 cytochrome c oxidase assembly protein
SETD2 SET domain containing 2
SH3KBP1 SH3-domain kinase binding protein 1
SHOC2 soc-2 suppressor of clear homolog (C. elegans)
SIRT5 sirtuin 5
SLAIN2 SLAIN motif family, member 2
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
THAP11 THAP domain containing 11
TMEM68 transmembrane protein 68
TNC tenascin C
TRAP1 TNF receptor-associated protein 1
VTI1B vesicle transport through interaction with t-SNAREs 1B
VWA8 von Willebrand factor A domain containing 8
WDR12 WD repeat domain 12
WDR36 WD repeat domain 36
WDR74 WD repeat domain 74
ZNF593 zinc finger protein 593