NCI-H748 Gene Set

Dataset Sanger Dependency Map Cancer Cell Line Proteomics
Category proteomics
Type cell line
Description cell line derived from Small Cell Lung Carcinoma Metastasis (Cell Model Passports, SIDM01117)
External Link https://cellmodelpassports.sanger.ac.uk/passports/SIDM01117
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Genes

197 proteins associated with the cell line NCI-H748 from the Sanger Dependency Map Cancer Cell Line Proteomics dataset.

Symbol Name
ARL3 ADP-ribosylation factor-like 3
ATAT1 alpha tubulin acetyltransferase 1
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast)
CCAR2 cell cycle and apoptosis regulator 2
CDC20 cell division cycle 20
CELF1 CUGBP, Elav-like family member 1
CHMP1B charged multivesicular body protein 1B
CMBL carboxymethylenebutenolidase homolog (Pseudomonas)
COPG2 coatomer protein complex, subunit gamma 2
CTPS1 CTP synthase 1
DCLK1 doublecortin-like kinase 1
DDX55 DEAD (Asp-Glu-Ala-Asp) box polypeptide 55
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DPYSL3 dihydropyrimidinase-like 3
DPYSL5 dihydropyrimidinase-like 5
FN3KRP fructosamine 3 kinase related protein
FOXJ3 forkhead box J3
FXR2 fragile X mental retardation, autosomal homolog 2
GDI1 GDP dissociation inhibitor 1
GLCE glucuronic acid epimerase
GNL1 guanine nucleotide binding protein-like 1
GSK3A glycogen synthase kinase 3 alpha
HAT1 histone acetyltransferase 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HSPH1 heat shock 105kDa/110kDa protein 1
IRGQ immunity-related GTPase family, Q
KDM4A lysine (K)-specific demethylase 4A
KIF16B kinesin family member 16B
KIF2A kinesin heavy chain member 2A
KIF4A kinesin family member 4A
KLC1 kinesin light chain 1
KLC2 kinesin light chain 2
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial)
LIG1 ligase I, DNA, ATP-dependent
MACF1 microtubule-actin crosslinking factor 1
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MED8 mediator complex subunit 8
MESTP4 mesoderm specific transcript pseudogene 4
MFSD1 major facilitator superfamily domain containing 1
MOB4 MOB family member 4, phocein
MSH2 mutS homolog 2
MSH6 mutS homolog 6
MYH10 myosin, heavy chain 10, non-muscle
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha
NAPB N-ethylmaleimide-sensitive factor attachment protein, beta
NCBP1 nuclear cap binding protein subunit 1, 80kDa
NECAB2 N-terminal EF-hand calcium binding protein 2
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21
PABPC3 poly(A) binding protein, cytoplasmic 3
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form)
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
PDS5B PDS5 cohesin associated factor B
PELO pelota homolog (Drosophila)
PEX6 peroxisomal biogenesis factor 6
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
PPCS phosphopantothenoylcysteine synthetase
PPIE peptidylprolyl isomerase E (cyclophilin E)
PPIH peptidylprolyl isomerase H (cyclophilin H)
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PPP5C protein phosphatase 5, catalytic subunit
PRPSAP2 phosphoribosyl pyrophosphate synthetase-associated protein 2
PSIP1 PC4 and SFRS1 interacting protein 1
RRM1 ribonucleotide reductase M1
SCG2 secretogranin II
SETD3 SET domain containing 3
SH3GLB2 SH3-domain GRB2-like endophilin B2
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SHPK sedoheptulokinase
SMAD4 SMAD family member 4
SMC1A structural maintenance of chromosomes 1A
SMC2 structural maintenance of chromosomes 2
SMC3 structural maintenance of chromosomes 3
SMS spermine synthase
SSRP1 structure specific recognition protein 1
STXBP1 syntaxin binding protein 1
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae)
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae)
TBCB tubulin folding cofactor B
TMPO thymopoietin
TRIM28 tripartite motif containing 28
TRIP13 thyroid hormone receptor interactor 13
TRIT1 tRNA isopentenyltransferase 1
TRMT6 tRNA methyltransferase 6
TUBAL3 tubulin, alpha-like 3
TUBB2B tubulin, beta 2B class IIb
UBA2 ubiquitin-like modifier activating enzyme 2
UBE2M ubiquitin-conjugating enzyme E2M
UBQLN2 ubiquilin 2
UPF3B UPF3 regulator of nonsense transcripts homolog B (yeast)
USP11 ubiquitin specific peptidase 11
WDR44 WD repeat domain 44
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRN2 5'-3' exoribonuclease 2
XTBD1 XRN2 binding domain containing 1
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
ZC3HAV1L zinc finger CCCH-type, antiviral 1-like
ZNF428 zinc finger protein 428

Symbol Name
AATF apoptosis antagonizing transcription factor
ACAD9 acyl-CoA dehydrogenase family, member 9
ACAT1 acetyl-CoA acetyltransferase 1
ACOT13 acyl-CoA thioesterase 13
AGRN agrin
ANXA2 annexin A2
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
BAG2 BCL2-associated athanogene 2
BCL2L13 BCL2-like 13 (apoptosis facilitator)
BOP1 block of proliferation 1
C2CD5 C2 calcium-dependent domain containing 5
CASP4 caspase 4, apoptosis-related cysteine peptidase
CCDC71L coiled-coil domain containing 71-like
CCNYL1 cyclin Y-like 1
CLCC1 chloride channel CLIC-like 1
CLMN calmin (calponin-like, transmembrane)
COL19A1 collagen, type XIX, alpha 1
COMT catechol-O-methyltransferase
DCAF8 DDB1 and CUL4 associated factor 8
DCXR dicarbonyl/L-xylulose reductase
DDR2 discoidin domain receptor tyrosine kinase 2
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
DTX3L deltex 3 like, E3 ubiquitin ligase
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EFL1 elongation factor like GTPase 1
EMG1 EMG1 N1-specific pseudouridine methyltransferase
ERCC5 excision repair cross-complementation group 5
ERGIC2 ERGIC and golgi 2
ETFA electron-transfer-flavoprotein, alpha polypeptide
ETFB electron-transfer-flavoprotein, beta polypeptide
EXOG endo/exonuclease (5'-3'), endonuclease G-like
FAM162A family with sequence similarity 162, member A
FBXO22 F-box protein 22
FGF11 fibroblast growth factor 11
GUF1 GUF1 GTPase homolog (S. cerevisiae)
GYS2 glycogen synthase 2 (liver)
HID1 HID1 domain containing
IGF1R insulin-like growth factor 1 receptor
KIF7 kinesin family member 7
LETM1 leucine zipper-EF-hand containing transmembrane protein 1
LOC105374691 uncharacterized LOC105374691
LYAR Ly1 antibody reactive
M6PR mannose-6-phosphate receptor (cation dependent)
MPHOSPH10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
MRPL12 mitochondrial ribosomal protein L12
MRPL16 mitochondrial ribosomal protein L16
MRPL20 mitochondrial ribosomal protein L20
MRPL40 mitochondrial ribosomal protein L40
MRPL54 mitochondrial ribosomal protein L54
MRPS21 mitochondrial ribosomal protein S21
NAA35 N(alpha)-acetyltransferase 35, NatC auxiliary subunit
NDC1 NDC1 transmembrane nucleoporin
NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa
NIFK nucleolar protein interacting with the FHA domain of MKI67
NOL11 nucleolar protein 11
NOP16 NOP16 nucleolar protein
NOP2 NOP2 nucleolar protein
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9
OTUD4 OTU deubiquitinase 4
PDCD11 programmed cell death 11
POLG polymerase (DNA directed), gamma
RCC1 regulator of chromosome condensation 1
RPL7L1 ribosomal protein L7-like 1
RRBP1 ribosome binding protein 1
RRP1 ribosomal RNA processing 1
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast)
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
RSL1D1 ribosomal L1 domain containing 1
SDC4 syndecan 4
SIL1 SIL1 nucleotide exchange factor
SLC30A7 solute carrier family 30 (zinc transporter), member 7
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SSR1 signal sequence receptor, alpha
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
STIM2 stromal interaction molecule 2
SUPT4H1 suppressor of Ty 4 homolog 1 (S. cerevisiae)
SVIL supervillin
TATDN1 TatD DNase domain containing 1
TBC1D24 TBC1 domain family, member 24
TDP1 tyrosyl-DNA phosphodiesterase 1
TFAP2D transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast)
TIMM23 translocase of inner mitochondrial membrane 23 homolog (yeast)
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast)
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM192 transmembrane protein 192
TOR1AIP1 torsin A interacting protein 1
TRUB2 TruB pseudouridine (psi) synthase family member 2
TSC22D4 TSC22 domain family, member 4
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)
VKORC1 vitamin K epoxide reductase complex, subunit 1
WDR43 WD repeat domain 43
XYLT2 xylosyltransferase II
YBX3 Y box binding protein 3
ZYX zyxin