NCI-N87 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
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Genes

231 genes with high or low expression in NCI-N87 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
CDK12 cyclin-dependent kinase 12 3.60177
MED1 mediator complex subunit 1 3.60177
WNT11 wingless-type MMTV integration site family, member 11 2.98204
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma 2.70591
CACNB1 calcium channel, voltage-dependent, beta 1 subunit 2.58313
EXPH5 exophilin 5 2.51825
SOWAHC sosondowah ankyrin repeat domain family member C 2.48111
KCNB2 potassium channel, voltage gated Shab related subfamily B, member 2 2.46076
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1 2.44091
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1 2.35145
C5AR1 complement component 5a receptor 1 2.19885
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1 2.19242
TCAP titin-cap 2.18841
IGSF9B immunoglobulin superfamily, member 9B 2.16648
LASP1 LIM and SH3 protein 1 2.15569
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta 2.15451
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 2.15114
GRB7 growth factor receptor-bound protein 7 2.14306
STARD3 StAR-related lipid transfer (START) domain containing 3 2.13542
ABLIM1 actin binding LIM protein 1 2.12755
ERBB2 erb-b2 receptor tyrosine kinase 2 2.10875
NR1H3 nuclear receptor subfamily 1, group H, member 3 2.04399
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 2.03196
ACTL8 actin-like 8 2.03081
GAN gigaxonin 2.01524
CTBP2 C-terminal binding protein 2 2.01484
PCGF2 polycomb group ring finger 2 1.97747
FGF20 fibroblast growth factor 20 1.97082
EPS8L1 EPS8-like 1 1.95777
WIPF2 WAS/WASL interacting protein family, member 2 1.9464
IVL involucrin 1.9438
CDC6 cell division cycle 6 1.93733
KRT23 keratin 23, type I 1.91231
TERF1 telomeric repeat binding factor (NIMA-interacting) 1 1.88416
SGPL1 sphingosine-1-phosphate lyase 1 1.88283
ODAM odontogenic, ameloblast asssociated 1.84688
LAD1 ladinin 1 1.83775
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 1.83508
PIK3C2G phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma 1.82938
EDAR ectodysplasin A receptor 1.82882
KRT17 keratin 17, type I 1.81462
GSC2 goosecoid homeobox 2 1.80805
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) 1.80088
FGF3 fibroblast growth factor 3 1.79715
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 1.78298
TNNI2 troponin I type 2 (skeletal, fast) 1.75383
PGAP3 post-GPI attachment to proteins 3 1.73348
MTPAP mitochondrial poly(A) polymerase 1.72819
UPK3B uroplakin 3B 1.72483
AQP5 aquaporin 5 1.72121
TCF20 transcription factor 20 (AR1) 1.71026
TNK2 tyrosine kinase, non-receptor, 2 1.70637
PCDH1 protocadherin 1 1.70092
PTPRU protein tyrosine phosphatase, receptor type, U 1.69731
MAOB monoamine oxidase B 1.69193
RABGAP1 RAB GTPase activating protein 1 1.68568
EPB42 erythrocyte membrane protein band 4.2 1.68567
KLK7 kallikrein-related peptidase 7 1.67326
PLA2G4B phospholipase A2, group IVB (cytosolic) 1.662
PADI1 peptidyl arginine deiminase, type I 1.65668
LOR loricrin 1.65126
RNF43 ring finger protein 43 1.64985
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 1.64806
MSLN mesothelin 1.64332
SHB Src homology 2 domain containing adaptor protein B 1.6411
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.63433
ARL15 ADP-ribosylation factor-like 15 1.6315
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae) 1.61423
GJB3 gap junction protein, beta 3, 31kDa 1.57717
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4 1.56294
SIM2 single-minded family bHLH transcription factor 2 1.54471
GOLIM4 golgi integral membrane protein 4 1.54091
ELOVL1 ELOVL fatty acid elongase 1 1.53667
GJC2 gap junction protein, gamma 2, 47kDa 1.53098
LLGL2 lethal giant larvae homolog 2 (Drosophila) 1.51825
TMEM63A transmembrane protein 63A 1.51481
GMPS guanine monphosphate synthase 1.51011
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1 1.48728
TMEM2 transmembrane protein 2 1.48624
EMP2 epithelial membrane protein 2 1.4798
PHLDB1 pleckstrin homology-like domain, family B, member 1 1.47342
KLK6 kallikrein-related peptidase 6 1.47294
ZNF551 zinc finger protein 551 1.46003
CASC3 cancer susceptibility candidate 3 1.45982
MED24 mediator complex subunit 24 1.44819
BMP4 bone morphogenetic protein 4 1.44799
PMEPA1 prostate transmembrane protein, androgen induced 1 1.44159
PEX16 peroxisomal biogenesis factor 16 1.43929
A4GALT alpha 1,4-galactosyltransferase 1.43723
PRR5 proline rich 5 (renal) 1.43448
PTK6 protein tyrosine kinase 6 1.43241
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 1.42515
FOXJ1 forkhead box J1 1.42445
MCTP1 multiple C2 domains, transmembrane 1 1.41844
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF 1.41751

low expression

Symbol Name Standardized Value
SNRPC small nuclear ribonucleoprotein polypeptide C -3.53725
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 -3.53701
STK19 serine/threonine kinase 19 -3.27925
ELOVL5 ELOVL fatty acid elongase 5 -3.14864
GSR glutathione reductase -2.5624
AQP4 aquaporin 4 -2.51795
AP4S1 adaptor-related protein complex 4, sigma 1 subunit -2.5022
MUT methylmalonyl CoA mutase -2.45647
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) -2.40944
STX12 syntaxin 12 -2.39299
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 -2.35706
STXBP6 syntaxin binding protein 6 (amisyn) -2.27151
PRR4 proline rich 4 (lacrimal) -2.2456
SEL1L sel-1 suppressor of lin-12-like (C. elegans) -2.22935
SIGLEC6 sialic acid binding Ig-like lectin 6 -2.20685
ZDHHC4 zinc finger, DHHC-type containing 4 -2.17412
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2 -2.16602
PTX3 pentraxin 3, long -2.14924
TIGD6 tigger transposable element derived 6 -2.14512
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 -2.13697
DLL3 delta-like 3 (Drosophila) -2.0914
NFU1 NFU1 iron-sulfur cluster scaffold -2.07618
ATP6V0E2 ATPase, H+ transporting V0 subunit e2 -2.06646
H2BFS H2B histone family, member S (pseudogene) -2.0584
ATP10A ATPase, class V, type 10A -2.03553
COPB1 coatomer protein complex, subunit beta 1 -2.00918
CNOT4 CCR4-NOT transcription complex, subunit 4 -2.0046
LSM8 LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) -1.99764
IFRD1 interferon-related developmental regulator 1 -1.96716
NCAM2 neural cell adhesion molecule 2 -1.9449
APIP APAF1 interacting protein -1.92825
NPHS1 nephrosis 1, congenital, Finnish type (nephrin) -1.92663
DEGS1 delta(4)-desaturase, sphingolipid 1 -1.92433
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A -1.92383
PIGF phosphatidylinositol glycan anchor biosynthesis, class F -1.89909
ENO3 enolase 3 (beta, muscle) -1.88445
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5 -1.8736
MARCH3 membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase -1.8652
GNG3 guanine nucleotide binding protein (G protein), gamma 3 -1.8644
GIMAP5 GTPase, IMAP family member 5 -1.85668
FRS2 fibroblast growth factor receptor substrate 2 -1.85014
TDP2 tyrosyl-DNA phosphodiesterase 2 -1.84691
PTGDS prostaglandin D2 synthase 21kDa (brain) -1.84516
RPAIN RPA interacting protein -1.84244
MRPL39 mitochondrial ribosomal protein L39 -1.84147
IRS2 insulin receptor substrate 2 -1.83008
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 -1.82659
ERG v-ets avian erythroblastosis virus E26 oncogene homolog -1.8231
CGGBP1 CGG triplet repeat binding protein 1 -1.82002
BAG4 BCL2-associated athanogene 4 -1.81955
TCP11L1 t-complex 11, testis-specific-like 1 -1.81763
HIST1H2BC histone cluster 1, H2bc -1.8143
CSNK2B casein kinase 2, beta polypeptide -1.80761
RNASE4 ribonuclease, RNase A family, 4 -1.80178
PTENP1 phosphatase and tensin homolog pseudogene 1 (functional) -1.79797
LOC644450 uncharacterized LOC644450 -1.79172
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 -1.77413
RRAS2 related RAS viral (r-ras) oncogene homolog 2 -1.77406
BMP8B bone morphogenetic protein 8b -1.7593
POT1 protection of telomeres 1 -1.74821
POLI polymerase (DNA directed) iota -1.74586
EIF1B eukaryotic translation initiation factor 1B -1.7374
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 -1.73666
COL13A1 collagen, type XIII, alpha 1 -1.72699
CLEC11A C-type lectin domain family 11, member A -1.7256
TMEM168 transmembrane protein 168 -1.71722
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 -1.70529
ZNF322P1 zinc finger protein 322 pseudogene 1 -1.70439
DHX16 DEAH (Asp-Glu-Ala-His) box polypeptide 16 -1.6968
TCEA1 transcription elongation factor A (SII), 1 -1.69117
TRIM27 tripartite motif containing 27 -1.67482
GOLT1B golgi transport 1B -1.67416
LHCGR luteinizing hormone/choriogonadotropin receptor -1.66536
CBR3 carbonyl reductase 3 -1.6646
NOL7 nucleolar protein 7, 27kDa -1.65919
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor -1.64566
TPP1 tripeptidyl peptidase I -1.64362
FBXL7 F-box and leucine-rich repeat protein 7 -1.642
LRRC31 leucine rich repeat containing 31 -1.64043
CHODL chondrolectin -1.63993
PMM1 phosphomannomutase 1 -1.63509
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 -1.62933
DAD1 defender against cell death 1 -1.62444
OXA1L oxidase (cytochrome c) assembly 1-like -1.602
PEX6 peroxisomal biogenesis factor 6 -1.59871
ICK intestinal cell (MAK-like) kinase -1.59808
CES2 carboxylesterase 2 -1.58726
MRPL15 mitochondrial ribosomal protein L15 -1.58243
KCNV1 potassium channel, voltage gated modifier subfamily V, member 1 -1.57633
CPM carboxypeptidase M -1.57557
MOB3B MOB kinase activator 3B -1.57036
RSC1A1 regulatory solute carrier protein, family 1, member 1 -1.56154
SEC23A Sec23 homolog A (S. cerevisiae) -1.55477
TBC1D19 TBC1 domain family, member 19 -1.55161
ZNF318 zinc finger protein 318 -1.54313
WWC3 WWC family member 3 -1.54174
ZNF552 zinc finger protein 552 -1.52975
CLIC4 chloride intracellular channel 4 -1.52844
SLC31A2 solute carrier family 31 (copper transporter), member 2 -1.52486
RANGRF RAN guanine nucleotide release factor -1.52022
SOAT1 sterol O-acyltransferase 1 -1.51867
MPO myeloperoxidase -1.51337
APCS amyloid P component, serum -1.51127
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 -1.50958
MTCL1 microtubule crosslinking factor 1 -1.50916
INHBA inhibin, beta A -1.50569
NELFE negative elongation factor complex member E -1.50206
FBXO9 F-box protein 9 -1.49822
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 -1.49607
TSG101 tumor susceptibility 101 -1.49094
DSCR3 Down syndrome critical region 3 -1.48562
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) -1.48054
ZNF277 zinc finger protein 277 -1.47566
MAGEB2 melanoma antigen family B2 -1.475
POU4F1 POU class 4 homeobox 1 -1.46444
USP16 ubiquitin specific peptidase 16 -1.46417
CCDC15 coiled-coil domain containing 15 -1.46276
GPS2 G protein pathway suppressor 2 -1.46056
NGDN neuroguidin, EIF4E binding protein -1.45872
BMX BMX non-receptor tyrosine kinase -1.45545
DCP1A decapping mRNA 1A -1.45468
NUP153 nucleoporin 153kDa -1.44847
FGL2 fibrinogen-like 2 -1.44556
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1 -1.44499
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 -1.44432
OLFM1 olfactomedin 1 -1.44287
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) -1.44076
WASF3 WAS protein family, member 3 -1.43893
STARD5 StAR-related lipid transfer (START) domain containing 5 -1.43631
DERL2 derlin 2 -1.4281
ZNF747 zinc finger protein 747 -1.42744
RNF5 ring finger protein 5, E3 ubiquitin protein ligase -1.42249
OR7E24 olfactory receptor, family 7, subfamily E, member 24 -1.422
CPA2 carboxypeptidase A2 (pancreatic) -1.42069
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow -1.41889
ABHD4 abhydrolase domain containing 4 -1.41631