NCK1 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description NCK adaptor protein 1|The protein encoded by this gene is one of the signaling and transforming proteins containing Src homology 2 and 3 (SH2 and SH3) domains. It is located in the cytoplasm and is an adaptor protein involved in transducing signals from receptor tyrosine kinases to downstream signal recipients such as RAS. Alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Jun 2010] (NCBI Entrez Gene Database, 4690)
External Link https://ncbi.nlm.nih.gov/gene/4690
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Genes

499 genes differentially expressed following the NCK1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
CXCL12 chemokine (C-X-C motif) ligand 12 0.0111475
CHEK2 checkpoint kinase 2 0.0110455
NTS neurotensin 0.0095935
IGFBP5 insulin-like growth factor binding protein 5 0.00891364
SEPP1 selenoprotein P, plasma, 1 0.00845859
ADD3 adducin 3 (gamma) 0.0082072
EIF5A eukaryotic translation initiation factor 5A 0.00801206
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.00796373
AUTS2 autism susceptibility candidate 2 0.00764424
NDN necdin, melanoma antigen (MAGE) family member 0.00755026
MARCKS myristoylated alanine-rich protein kinase C substrate 0.00746889
CCNA2 cyclin A2 0.00741128
NELL2 NEL-like 2 (chicken) 0.00715366
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 0.0071311
CARHSP1 calcium regulated heat stable protein 1, 24kDa 0.00697238
SFRP1 secreted frizzled-related protein 1 0.00696738
RBM3 RNA binding motif (RNP1, RRM) protein 3 0.00692394
BIRC5 baculoviral IAP repeat containing 5 0.00683978
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.00680098
CPVL carboxypeptidase, vitellogenic-like 0.00677538
PEG10 paternally expressed 10 0.00673297
MDK midkine (neurite growth-promoting factor 2) 0.00666316
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 0.00660552
KIF20A kinesin family member 20A 0.00651056
WDR61 WD repeat domain 61 0.00640487
DACH1 dachshund family transcription factor 1 0.0064044
PDIA3 protein disulfide isomerase family A, member 3 0.00640373
AURKB aurora kinase B 0.00639796
BPHL biphenyl hydrolase-like (serine hydrolase) 0.00637293
LTBP1 latent transforming growth factor beta binding protein 1 0.00636879
NQO2 NAD(P)H dehydrogenase, quinone 2 0.00633115
ECI2 enoyl-CoA delta isomerase 2 0.00621548
ANXA6 annexin A6 0.00618137
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.00615006
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide 0.00612646
NREP neuronal regeneration related protein 0.00610664
CXCR4 chemokine (C-X-C motif) receptor 4 0.006106
ACAT2 acetyl-CoA acetyltransferase 2 0.00610229
SORD sorbitol dehydrogenase 0.00608854
SEC23A Sec23 homolog A (S. cerevisiae) 0.00603749
SIRT3 sirtuin 3 0.00596394
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 0.0059632
SHTN1 shootin 1 0.00595732
FAM171A1 family with sequence similarity 171, member A1 0.00588986
HOXC6 homeobox C6 0.0058439
ARID4A AT rich interactive domain 4A (RBP1-like) 0.00582153
RESF1 retroelement silencing factor 1 0.00581712
DPYSL2 dihydropyrimidinase-like 2 0.00580316
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.00579227
EPHB2 EPH receptor B2 0.00579052
CYCS cytochrome c, somatic 0.00578608
PBX1 pre-B-cell leukemia homeobox 1 0.00578476
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 0.00577159
SPTSSA serine palmitoyltransferase, small subunit A 0.00576764
OIP5 Opa interacting protein 5 0.00575174
NLRP2 NLR family, pyrin domain containing 2 0.00575014
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.00574643
NEK2 NIMA-related kinase 2 0.00569766
CCNI cyclin I 0.00569083
MAP2K6 mitogen-activated protein kinase kinase 6 0.00568807
GPR65 G protein-coupled receptor 65 0.00564934
CETN2 centrin, EF-hand protein, 2 0.00562958
STX10 syntaxin 10 0.00562032
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.00560263
CD48 CD48 molecule 0.00559316
RAD23B RAD23 homolog B (S. cerevisiae) 0.00559297
TPX2 TPX2, microtubule-associated 0.00558879
SEPHS1 selenophosphate synthetase 1 0.00557288
PER3 period circadian clock 3 0.00552304
HILPDA hypoxia inducible lipid droplet-associated 0.00550428
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.00549554
HMGB2 high mobility group box 2 0.00548926
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 0.00545998
NR2F1 nuclear receptor subfamily 2, group F, member 1 0.00543975
TTC3 tetratricopeptide repeat domain 3 0.00543846
VCAN versican 0.00543143
NUSAP1 nucleolar and spindle associated protein 1 0.0054039
PRDX2 peroxiredoxin 2 0.00540228
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.00539691
CALB1 calbindin 1, 28kDa 0.00539177
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase 0.00538861
EREG epiregulin 0.00538358
IGF1 insulin-like growth factor 1 (somatomedin C) 0.00537055
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial 0.00533393
IQGAP2 IQ motif containing GTPase activating protein 2 0.00533343
GCA grancalcin, EF-hand calcium binding protein 0.0053024
WT1 Wilms tumor 1 0.00530213
HMGN4 high mobility group nucleosomal binding domain 4 0.00529945
AZIN1 antizyme inhibitor 1 0.00528671
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.00528634
PPA2 pyrophosphatase (inorganic) 2 0.00526169
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 0.0052298
MAL mal, T-cell differentiation protein 0.00522678
OTULINL OTU deubiquitinase with linear linkage specificity like 0.00522658
THAP9-AS1 THAP9 antisense RNA 1 0.00522144
PIMREG PICALM interacting mitotic regulator 0.0052208
CALML4 calmodulin-like 4 0.00520615
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.0051999
LBR lamin B receptor 0.00519975
PRKCB protein kinase C, beta 0.00519856
LARS1 leucyl-tRNA synthetase 1 0.00519085
DCXR dicarbonyl/L-xylulose reductase 0.00517562
C7 complement component 7 0.0051713
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma 0.00517066
TUBB2A tubulin, beta 2A class IIa 0.00514698
DPYSL3 dihydropyrimidinase-like 3 0.00512714
ADRA2A adrenoceptor alpha 2A 0.00508721
KIF11 kinesin family member 11 0.00507626
ERAP2 endoplasmic reticulum aminopeptidase 2 0.00507547
BUB1 BUB1 mitotic checkpoint serine/threonine kinase 0.00507263
PNMA2 paraneoplastic Ma antigen 2 0.00506912
AOC1 amine oxidase, copper containing 1 0.00503328
CD2 CD2 molecule 0.00502533
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 0.00502181
GLIPR1 GLI pathogenesis-related 1 0.00502127
ENOPH1 enolase-phosphatase 1 0.00498652
SRSF7 serine/arginine-rich splicing factor 7 0.00497658
IFT52 intraflagellar transport 52 0.0049685
CTSC cathepsin C 0.00496462
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.00495936
CAPZB capping protein (actin filament) muscle Z-line, beta 0.00495898
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 0.0049552
TMEM38B transmembrane protein 38B 0.00495408
COL1A2 collagen, type I, alpha 2 0.00495332
NELL1 NEL-like 1 (chicken) 0.00495207
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 0.0049381
HMGN5 high mobility group nucleosome binding domain 5 0.00493595
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 0.00491932
THYN1 thymocyte nuclear protein 1 0.00491046
DDAH2 dimethylarginine dimethylaminohydrolase 2 0.00488212
TIA1 TIA1 cytotoxic granule-associated RNA binding protein 0.00487697
COPS4 COP9 signalosome subunit 4 0.00485241
PADI2 peptidyl arginine deiminase, type II 0.0048411
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.0048355
CHEK1 checkpoint kinase 1 0.00483398
TMEM106B transmembrane protein 106B 0.0048122
MAGT1 magnesium transporter 1 0.00479831
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9) 0.00479761
GINS2 GINS complex subunit 2 (Psf2 homolog) 0.00479117
HBB hemoglobin, beta 0.00478936
SUN1 Sad1 and UNC84 domain containing 1 0.00478433
MSMO1 methylsterol monooxygenase 1 0.00477938
TSPAN8 tetraspanin 8 0.00477237
ARRB2 arrestin, beta 2 0.00475954
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 0.00474873
ADORA2B adenosine A2b receptor 0.00472751
MSLN mesothelin 0.00472187
CENPF centromere protein F, 350/400kDa 0.00471886
LMNB1 lamin B1 0.00471097
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 0.00470753
STEAP1 six transmembrane epithelial antigen of the prostate 1 0.00470065
FBN1 fibrillin 1 0.00469135
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 0.00465191
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 0.00464387
TREM1 triggering receptor expressed on myeloid cells 1 0.00463657
EGR3 early growth response 3 0.00461823
RFC2 replication factor C (activator 1) 2, 40kDa 0.00460598
HAL histidine ammonia-lyase 0.00459961
INSIG1 insulin induced gene 1 0.00459743
G3BP2 GTPase activating protein (SH3 domain) binding protein 2 0.0045733
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 0.0045723
BMP4 bone morphogenetic protein 4 0.0045559
CCNA1 cyclin A1 0.00455368
ZDHHC6 zinc finger, DHHC-type containing 6 0.00454185
TRMT5 tRNA methyltransferase 5 0.00453945
EVI2A ecotropic viral integration site 2A 0.00453831
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1 0.00453303
ATP8B4 ATPase, class I, type 8B, member 4 0.00452695
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial 0.00452456
JAKMIP2 janus kinase and microtubule interacting protein 2 0.00452273
PRIM1 primase, DNA, polypeptide 1 (49kDa) 0.00452079
ARL3 ADP-ribosylation factor-like 3 0.00450901
SOX11 SRY (sex determining region Y)-box 11 0.00450533
MYL6B myosin, light chain 6B, alkali, smooth muscle and non-muscle 0.00449922
TSPAN6 tetraspanin 6 0.00449169
CES1 carboxylesterase 1 0.00448563
MUC16 mucin 16, cell surface associated 0.00448414
FKBP10 FK506 binding protein 10, 65 kDa 0.00448384
DAXX death-domain associated protein 0.00448223
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme 0.00447779
TKTL1 transketolase-like 1 0.00447517
CDK1 cyclin-dependent kinase 1 0.00446253
HPF1 histone PARylation factor 1 0.00446058
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) 0.00445177
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.00445105
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 0.00444487
GNG4 guanine nucleotide binding protein (G protein), gamma 4 0.00444319
MARCHF1 membrane associated ring-CH-type finger 1 0.00443947
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) 0.00443544
NUP37 nucleoporin 37kDa 0.00443098
CD1C CD1c molecule 0.00442998
ZNF467 zinc finger protein 467 0.00442877
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) 0.00442832
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1 0.00442588
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.00441904
ZNF266 zinc finger protein 266 0.00441903
PSRC1 proline/serine-rich coiled-coil 1 0.00441151
NMU neuromedin U 0.00440922
ELOVL6 ELOVL fatty acid elongase 6 0.00440869
FABP6 fatty acid binding protein 6, ileal 0.00440674
RNF5 ring finger protein 5, E3 ubiquitin protein ligase 0.00438886
RPL26L1 ribosomal protein L26-like 1 0.00438395
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 0.00437959
FYB1 FYN binding protein 1 0.00437496
CLC Charcot-Leyden crystal galectin 0.00436163
FHOD3 formin homology 2 domain containing 3 0.00435021
MEX3D mex-3 RNA binding family member D 0.00434651
FUS FUS RNA binding protein 0.00433745
LEFTY1 left-right determination factor 1 0.00433679
HSDL2 hydroxysteroid dehydrogenase like 2 0.0043335
KLK8 kallikrein-related peptidase 8 0.00431612
RNF167 ring finger protein 167 0.00431565
RNASEH2A ribonuclease H2, subunit A 0.00430399
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) 0.00430079
KRCC1 lysine-rich coiled-coil 1 0.00429646
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.00428524
CFD complement factor D (adipsin) 0.00427937
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 0.00427464
MRPS18B mitochondrial ribosomal protein S18B 0.00427304
GRB7 growth factor receptor-bound protein 7 0.00426768
CPOX coproporphyrinogen oxidase 0.0042609
SHLD2 shieldin complex subunit 2 0.00425764
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.0042558
ITK IL2-inducible T-cell kinase 0.00425056
CD3G CD3g molecule, gamma (CD3-TCR complex) 0.0042468
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 0.00423546
TIMELESS timeless circadian clock 0.00423248
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 0.00423093
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 0.00422803
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 0.00422372
GPX4 glutathione peroxidase 4 0.00421838
PGM1 phosphoglucomutase 1 0.00421235
ASF1B anti-silencing function 1B histone chaperone 0.0042121
SMC1A structural maintenance of chromosomes 1A 0.00421108
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 0.00421042
ACE2 angiotensin I converting enzyme 2 0.00420127
UBE2E3 ubiquitin-conjugating enzyme E2E 3 0.0042006
F2R coagulation factor II (thrombin) receptor 0.00419458
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 0.00419274
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 0.00419216
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 0.00417762
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa 0.00415928
KDM3A lysine (K)-specific demethylase 3A 0.00415892
DEGS1 delta(4)-desaturase, sphingolipid 1 0.00415812
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 0.00415315
SSR2 signal sequence receptor, beta (translocon-associated protein beta) 0.00414988
ZFP36L1 ZFP36 ring finger protein-like 1 0.00414927
XCL1 chemokine (C motif) ligand 1 0.00413997
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 0.00413595

decreased expression

Symbol Name Standardized Value
TCTA T-cell leukemia translocation altered -0.014687
IFI27 interferon, alpha-inducible protein 27 -0.0125341
BAMBI BMP and activin membrane-bound inhibitor -0.012263
KRT14 keratin 14, type I -0.0121649
PROM1 prominin 1 -0.0103927
PERP PERP, TP53 apoptosis effector -0.00996678
PMP22 peripheral myelin protein 22 -0.00994024
S100A8 S100 calcium binding protein A8 -0.00987173
HSPA1A heat shock 70kDa protein 1A -0.00969593
APOD apolipoprotein D -0.00966185
GPNMB glycoprotein (transmembrane) nmb -0.00961208
KRT17 keratin 17, type I -0.00949093
DYNLL1 dynein, light chain, LC8-type 1 -0.00938924
CRYAB crystallin, alpha B -0.00930574
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.00906508
MT1X metallothionein 1X -0.00894144
IGF1R insulin-like growth factor 1 receptor -0.00868016
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -0.00855782
HIST1H2BK histone cluster 1, H2bk -0.00852892
MX1 MX dynamin-like GTPase 1 -0.00852886
GADD45A growth arrest and DNA-damage-inducible, alpha -0.00839643
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.00796103
WASL Wiskott-Aldrich syndrome-like -0.00781313
IRF9 interferon regulatory factor 9 -0.00772267
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) -0.0076869
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 -0.00761784
MGLL monoglyceride lipase -0.00754123
SLC38A1 solute carrier family 38, member 1 -0.00746121
PLAAT3 phospholipase A and acyltransferase 3 -0.00742438
KRT23 keratin 23, type I -0.00741533
TRIM22 tripartite motif containing 22 -0.00740163
CXCL2 chemokine (C-X-C motif) ligand 2 -0.0073737
C1QB complement component 1, q subcomponent, B chain -0.0073181
PLK2 polo-like kinase 2 -0.00725226
HMOX1 heme oxygenase 1 -0.0071995
MET MET proto-oncogene, receptor tyrosine kinase -0.00716809
MTUS1 microtubule associated tumor suppressor 1 -0.00714692
KRT5 keratin 5, type II -0.00705838
ZFP36 ZFP36 ring finger protein -0.00695408
SIK1 salt-inducible kinase 1 -0.00693496
PFN2 profilin 2 -0.00688783
SMAD7 SMAD family member 7 -0.00683085
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -0.00679125
KRT6A keratin 6A, type II -0.00671148
AMOTL2 angiomotin like 2 -0.00668954
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) -0.00668062
NUPR1 nuclear protein, transcriptional regulator, 1 -0.00664898
SFN stratifin -0.00663141
MTCL1 microtubule crosslinking factor 1 -0.00656357
MT1G metallothionein 1G -0.00654394
AQP1 aquaporin 1 (Colton blood group) -0.00651962
H1-2 H1.2 linker histone, cluster member -0.00636473
SCRG1 stimulator of chondrogenesis 1 -0.00635143
STC2 stanniocalcin 2 -0.00635109
TRIM29 tripartite motif containing 29 -0.00635015
SPP1 secreted phosphoprotein 1 -0.00634822
REXO2 RNA exonuclease 2 -0.00630318
SPRED2 sprouty-related, EVH1 domain containing 2 -0.00629185
IFI6 interferon, alpha-inducible protein 6 -0.00623937
FNDC3B fibronectin type III domain containing 3B -0.00623466
ISG20 interferon stimulated exonuclease gene 20kDa -0.00621388
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -0.0062131
GNAS GNAS complex locus -0.00614129
RFX5 regulatory factor X, 5 (influences HLA class II expression) -0.00610527
SLC31A2 solute carrier family 31 (copper transporter), member 2 -0.00608534
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 -0.00605654
SWAP70 SWAP switching B-cell complex 70kDa subunit -0.00600349
CTSZ cathepsin Z -0.00599411
MT1M metallothionein 1M -0.0059648
GSN gelsolin -0.00594443
GRN granulin -0.00590311
EHD3 EH-domain containing 3 -0.00588437
CXCL10 chemokine (C-X-C motif) ligand 10 -0.00587761
MVP major vault protein -0.0058727
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 -0.00586814
CTTN cortactin -0.0058637
KLF2 Kruppel-like factor 2 -0.00584918
SCUBE2 signal peptide, CUB domain, EGF-like 2 -0.00582623
KANK1 KN motif and ankyrin repeat domains 1 -0.00580431
C1QA complement component 1, q subcomponent, A chain -0.00571754
KRT7 keratin 7, type II -0.00570931
TPST2 tyrosylprotein sulfotransferase 2 -0.00570149
S100A11 S100 calcium binding protein A11 -0.00566444
RNH1 ribonuclease/angiogenin inhibitor 1 -0.00564875
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa -0.0056413
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 -0.00564007
CD40 CD40 molecule, TNF receptor superfamily member 5 -0.00563973
SPTBN1 spectrin, beta, non-erythrocytic 1 -0.00563958
AMDHD2 amidohydrolase domain containing 2 -0.00563505
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -0.00563422
UBE2L6 ubiquitin-conjugating enzyme E2L 6 -0.00562839
SOCS2 suppressor of cytokine signaling 2 -0.00562795
RND3 Rho family GTPase 3 -0.00559567
KLF5 Kruppel-like factor 5 (intestinal) -0.00558894
CD58 CD58 molecule -0.00557302
KLK11 kallikrein-related peptidase 11 -0.00556568
ZMAT3 zinc finger, matrin-type 3 -0.00556193
ISG15 ISG15 ubiquitin-like modifier -0.0055604
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 -0.00555205
TRIP6 thyroid hormone receptor interactor 6 -0.00552957
TRAF3IP2 TRAF3 interacting protein 2 -0.00549119
CSTA cystatin A (stefin A) -0.00548444
IER5 immediate early response 5 -0.0054689
TENT5A terminal nucleotidyltransferase 5A -0.00546686
NOTCH1 notch 1 -0.00546376
SPRY4 sprouty homolog 4 (Drosophila) -0.00546018
KPNA6 karyopherin alpha 6 (importin alpha 7) -0.00545776
SAMD4A sterile alpha motif domain containing 4A -0.00545712
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A -0.00545144
CCND3 cyclin D3 -0.00541655
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 -0.00541347
NFE2L1 nuclear factor, erythroid 2-like 1 -0.00540189
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 -0.00539188
ARHGAP29 Rho GTPase activating protein 29 -0.0053722
TP63 tumor protein p63 -0.00536937
DRAM1 DNA-damage regulated autophagy modulator 1 -0.00535952
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide -0.00535722
COL11A1 collagen, type XI, alpha 1 -0.00534602
CNOT7 CCR4-NOT transcription complex, subunit 7 -0.00534032
ETV5 ets variant 5 -0.00534007
KRT16 keratin 16, type I -0.00533178
BTG1 B-cell translocation gene 1, anti-proliferative -0.00531914
INHBA inhibin, beta A -0.0053155
FOXD1 forkhead box D1 -0.00531081
PDGFA platelet-derived growth factor alpha polypeptide -0.00530036
DOCK9 dedicator of cytokinesis 9 -0.00528209
SPHK1 sphingosine kinase 1 -0.00526968
STAT1 signal transducer and activator of transcription 1, 91kDa -0.00526455
GPER1 G protein-coupled estrogen receptor 1 -0.00523782
MFAP5 microfibrillar associated protein 5 -0.00522197
RFTN1 raftlin, lipid raft linker 1 -0.00518742
TGFBR3 transforming growth factor, beta receptor III -0.00517964
PDPK1 3-phosphoinositide dependent protein kinase 1 -0.00517091
MBNL2 muscleblind-like splicing regulator 2 -0.00514068
GYG1 glycogenin 1 -0.00513671
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.00510251
KRT6B keratin 6B, type II -0.00508431
PARP12 poly (ADP-ribose) polymerase family, member 12 -0.00508094
AMIGO2 adhesion molecule with Ig-like domain 2 -0.00507985
SEC14L1 SEC14-like 1 (S. cerevisiae) -0.00507154
ZCCHC2 zinc finger, CCHC domain containing 2 -0.00506786
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5 -0.00505988
TM4SF1 transmembrane 4 L six family member 1 -0.00505866
HIST1H2BD histone cluster 1, H2bd -0.00505533
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 -0.0050487
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa -0.00504165
FTH1 ferritin, heavy polypeptide 1 -0.00503205
S100A9 S100 calcium binding protein A9 -0.00502036
LYPD3 LY6/PLAUR domain containing 3 -0.00500726
SPRR1B small proline-rich protein 1B -0.00497951
ADIRF adipogenesis regulatory factor -0.00497593
SCPEP1 serine carboxypeptidase 1 -0.00497478
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) -0.00497474
FXYD3 FXYD domain containing ion transport regulator 3 -0.00496812
GOLGA8H golgin A8 family, member H -0.00495286
TXLNA taxilin alpha -0.00495229
FHL2 four and a half LIM domains 2 -0.00494848
CA2 carbonic anhydrase II -0.00493681
TIMP1 TIMP metallopeptidase inhibitor 1 -0.00491806
CAPN1 calpain 1, (mu/I) large subunit -0.00491634
CXCL9 chemokine (C-X-C motif) ligand 9 -0.00490601
IRS1 insulin receptor substrate 1 -0.00490135
MITF microphthalmia-associated transcription factor -0.00488668
LRP4 low density lipoprotein receptor-related protein 4 -0.00487901
SUSD6 sushi domain containing 6 -0.00487828
MXRA7 matrix-remodelling associated 7 -0.00487172
MAN2A1 mannosidase, alpha, class 2A, member 1 -0.00484592
TMEM131L transmembrane 131 like -0.00484088
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 -0.00483457
BCL2L2 BCL2-like 2 -0.00482411
BST2 bone marrow stromal cell antigen 2 -0.00480818
TNS3 tensin 3 -0.00480633
TACSTD2 tumor-associated calcium signal transducer 2 -0.00480133
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 -0.00479998
LDOC1 leucine zipper, down-regulated in cancer 1 -0.00479988
ARMCX3 armadillo repeat containing, X-linked 3 -0.00479812
MYC v-myc avian myelocytomatosis viral oncogene homolog -0.00479514
PDLIM4 PDZ and LIM domain 4 -0.00479492
NNMT nicotinamide N-methyltransferase -0.00479431
APOL1 apolipoprotein L, 1 -0.00479174
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 -0.00478691
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 -0.00478187
LAMC2 laminin, gamma 2 -0.00475989
WARS1 tryptophanyl-tRNA synthetase 1 -0.00475162
XPO7 exportin 7 -0.00474809
HSPH1 heat shock 105kDa/110kDa protein 1 -0.00473161
TSC22D2 TSC22 domain family, member 2 -0.00473135
ITSN2 intersectin 2 -0.00472484
ANXA4 annexin A4 -0.00472096
OXTR oxytocin receptor -0.00471226
HIST1H2AC histone cluster 1, H2ac -0.00470074
AHNAK2 AHNAK nucleoprotein 2 -0.00468886
RGS16 regulator of G-protein signaling 16 -0.00468627
KRT34 keratin 34, type I -0.00468571
DKK4 dickkopf WNT signaling pathway inhibitor 4 -0.00467905
PPL periplakin -0.00467584
CEMIP2 cell migration inducing hyaluronidase 2 -0.00467001
HLA-F major histocompatibility complex, class I, F -0.00466813
CTSD cathepsin D -0.00466642
HIST2H2BE histone cluster 2, H2be -0.00466012
TSLIG3A tRNA splicing ligase complex subunit 3A -0.00465769
TUFT1 tuftelin 1 -0.00465358
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -0.00464664
PTPRK protein tyrosine phosphatase, receptor type, K -0.00464437
VLDLR very low density lipoprotein receptor -0.00464052
MAOB monoamine oxidase B -0.0046346
SLC39A14 solute carrier family 39 (zinc transporter), member 14 -0.00463091
GDF15 growth differentiation factor 15 -0.00462341
PPP1R15A protein phosphatase 1, regulatory subunit 15A -0.00461812
KLF9 Kruppel-like factor 9 -0.00460885
IGF2R insulin-like growth factor 2 receptor -0.00460224
FADS3 fatty acid desaturase 3 -0.00460041
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing -0.00459647
FKBP11 FK506 binding protein 11, 19 kDa -0.00458745
KLK10 kallikrein-related peptidase 10 -0.00458628
ITPKB inositol-trisphosphate 3-kinase B -0.0045763
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) -0.00455637
SNAI2 snail family zinc finger 2 -0.00454219
RGS2 regulator of G-protein signaling 2 -0.0045385
TIMP3 TIMP metallopeptidase inhibitor 3 -0.00452603
EFHD1 EF-hand domain family, member D1 -0.00452206
CXCL8 chemokine (C-X-C motif) ligand 8 -0.0045079
MAP7 microtubule-associated protein 7 -0.00448556
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -0.00447869
COL16A1 collagen, type XVI, alpha 1 -0.00446585
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 -0.0044652
HOPX HOP homeobox -0.00446228
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A -0.00444071
RTN2 reticulon 2 -0.00443509
AKAP9 A kinase (PRKA) anchor protein 9 -0.0044106
PIP prolactin-induced protein -0.00440583
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 -0.00439704
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 -0.00439034
GSTP1 glutathione S-transferase pi 1 -0.00438497
GPX1 glutathione peroxidase 1 -0.0043817
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) -0.00437973
KRT15 keratin 15, type I -0.00437531
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 -0.00436211
PLK3 polo-like kinase 3 -0.00435258
SOX4 SRY (sex determining region Y)-box 4 -0.00435239
POSTN periostin, osteoblast specific factor -0.00435172
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -0.00435102
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 -0.00434906
TMCC1 transmembrane and coiled-coil domain family 1 -0.00434879
CTSL cathepsin L -0.00434811
SLC30A1 solute carrier family 30 (zinc transporter), member 1 -0.00434731
NRCAM neuronal cell adhesion molecule -0.0043432
DIO2 deiodinase, iodothyronine, type II -0.00433845
CX3CL1 chemokine (C-X3-C motif) ligand 1 -0.00433481
FOXO1 forkhead box O1 -0.00433223