NDC80 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description NDC80 kinetochore complex component|This gene encodes a component of the NDC80 kinetochore complex. The encoded protein consists of an N-terminal microtubule binding domain and a C-terminal coiled-coiled domain that interacts with other components of the complex. This protein functions to organize and stabilize microtubule-kinetochore interactions and is required for proper chromosome segregation. [provided by RefSeq, Oct 2011] (NCBI Entrez Gene Database, 10403)
External Link https://ncbi.nlm.nih.gov/gene/10403
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Genes

500 genes differentially expressed following the NDC80 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
SSBP2 single-stranded DNA binding protein 2 0.0366085
CDCA4 cell division cycle associated 4 0.0145948
ITM2A integral membrane protein 2A 0.0136557
PRDX2 peroxiredoxin 2 0.0127946
TCTA T-cell leukemia translocation altered 0.0127745
RHOBTB3 Rho-related BTB domain containing 3 0.0123005
SRSF1 serine/arginine-rich splicing factor 1 0.0122777
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 0.0120736
BMP4 bone morphogenetic protein 4 0.0118555
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon 0.0115134
LUC7L3 LUC7-like 3 (S. cerevisiae) 0.0112009
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.011047
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 0.0109146
NREP neuronal regeneration related protein 0.0106993
ARGLU1 arginine and glutamate rich 1 0.0106092
KIF20A kinesin family member 20A 0.0104535
GRIA2 glutamate receptor, ionotropic, AMPA 2 0.0104516
NTS neurotensin 0.0104029
CALCA calcitonin-related polypeptide alpha 0.0102104
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 0.00992195
PTCH1 patched 1 0.00985859
NELL2 NEL-like 2 (chicken) 0.00978435
ZDHHC6 zinc finger, DHHC-type containing 6 0.00973194
CXADR coxsackie virus and adenovirus receptor 0.00944561
CD99 CD99 molecule 0.00923757
PCSK1 proprotein convertase subtilisin/kexin type 1 0.00917922
ITPRID2 ITPR interacting domain containing 2 0.00909314
OLFM1 olfactomedin 1 0.00894034
PDZD2 PDZ domain containing 2 0.00887643
CPB1 carboxypeptidase B1 (tissue) 0.0088464
SEPP1 selenoprotein P, plasma, 1 0.00879822
HNRNPR heterogeneous nuclear ribonucleoprotein R 0.00879055
MPPED2 metallophosphoesterase domain containing 2 0.00862238
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.00857747
AUTS2 autism susceptibility candidate 2 0.00853951
CALCB calcitonin-related polypeptide beta 0.00846932
FUBP1 far upstream element (FUSE) binding protein 1 0.00835337
PNISR PNN-interacting serine/arginine-rich protein 0.00829641
ADGRG2 adhesion G protein-coupled receptor G2 0.00826605
RHOA ras homolog family member A 0.00824803
PLBD1 phospholipase B domain containing 1 0.00816714
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.00812239
BCLAF1 BCL2-associated transcription factor 1 0.00803582
HMGB1 high mobility group box 1 0.00802175
EDNRB endothelin receptor type B 0.00799251
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.00796396
LEF1 lymphoid enhancer-binding factor 1 0.00796095
ATAD2 ATPase family, AAA domain containing 2 0.00789755
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.00785773
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.00784616
HP haptoglobin 0.00780438
ELP1 elongator acetyltransferase complex subunit 1 0.00773235
SMC1A structural maintenance of chromosomes 1A 0.00771814
PRKCB protein kinase C, beta 0.00769781
OGT O-linked N-acetylglucosamine (GlcNAc) transferase 0.00766709
SRSF6 serine/arginine-rich splicing factor 6 0.00758146
PNN pinin, desmosome associated protein 0.00755431
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 0.0075458
ITGA6 integrin, alpha 6 0.00752269
NDNF neuron-derived neurotrophic factor 0.00752147
SLIT2 slit homolog 2 (Drosophila) 0.00751797
PRPF3 pre-mRNA processing factor 3 0.00751603
RAD21 RAD21 homolog (S. pombe) 0.00749062
MSN moesin 0.00746267
FLRT3 fibronectin leucine rich transmembrane protein 3 0.00743384
RDX radixin 0.00741439
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) 0.007409
HACD3 3-hydroxyacyl-CoA dehydratase 3 0.00740291
MGP matrix Gla protein 0.00740146
S100P S100 calcium binding protein P 0.00736143
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.0073401
CNR1 cannabinoid receptor 1 (brain) 0.00730287
SCAMP1 secretory carrier membrane protein 1 0.00723578
RPL10 ribosomal protein L10 0.00717537
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 0.0071621
TLK2 tousled-like kinase 2 0.00715184
PODXL podocalyxin-like 0.00710845
MAN2A1 mannosidase, alpha, class 2A, member 1 0.00710725
EIF1AX eukaryotic translation initiation factor 1A, X-linked 0.0070907
MSL2 male-specific lethal 2 homolog (Drosophila) 0.00707934
RESF1 retroelement silencing factor 1 0.00707649
F13A1 coagulation factor XIII, A1 polypeptide 0.00704005
TRIM44 tripartite motif containing 44 0.00703807
HNRNPK heterogeneous nuclear ribonucleoprotein K 0.00703188
SPC25 SPC25, NDC80 kinetochore complex component 0.00701691
CPD carboxypeptidase D 0.00701667
NQO2 NAD(P)H dehydrogenase, quinone 2 0.00700389
GPC4 glypican 4 0.00696623
TPM4 tropomyosin 4 0.00693131
PDZK1IP1 PDZK1 interacting protein 1 0.00693074
IPO5 importin 5 0.00692019
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A 0.00691984
ANOS1 anosmin 1 0.00691729
CEP55 centrosomal protein 55kDa 0.00690177
DAPK1 death-associated protein kinase 1 0.00689031
NOP56 NOP56 ribonucleoprotein 0.00688823
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 0.00687774
COL1A2 collagen, type I, alpha 2 0.00684344
RUFY3 RUN and FYVE domain containing 3 0.0068245
MRPS30 mitochondrial ribosomal protein S30 0.00680984
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.00680387
KIF23 kinesin family member 23 0.0067833
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) 0.00678226
PAXBP1 PAX3 and PAX7 binding protein 1 0.00676726
MATN2 matrilin 2 0.00676205
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 0.00675572
HHEX hematopoietically expressed homeobox 0.00674237
CREBZF CREB/ATF bZIP transcription factor 0.00671411
NKTR natural killer cell triggering receptor 0.00669178
ZMYND11 zinc finger, MYND-type containing 11 0.00669132
DCHS1 dachsous cadherin-related 1 0.00667167
JARID2 jumonji, AT rich interactive domain 2 0.00666089
CDA cytidine deaminase 0.00664738
SLTM SAFB-like, transcription modulator 0.00664115
CHI3L2 chitinase 3-like 2 0.00663951
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.00663837
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 0.00663252
MCM3 minichromosome maintenance complex component 3 0.0066162
HAPLN1 hyaluronan and proteoglycan link protein 1 0.00658548
KLHL23 kelch-like family member 23 0.00658288
DAZAP1 DAZ associated protein 1 0.00657215
REEP1 receptor accessory protein 1 0.00657155
ACTC1 actin, alpha, cardiac muscle 1 0.0065697
PLAT plasminogen activator, tissue 0.00654443
RBM26 RNA binding motif protein 26 0.00654027
RSRP1 arginine/serine-rich protein 1 0.00653241
PELI2 pellino E3 ubiquitin protein ligase family member 2 0.00651192
CD14 CD14 molecule 0.00651056
DACH1 dachshund family transcription factor 1 0.0065005
FRS2 fibroblast growth factor receptor substrate 2 0.0064905
TENT5A terminal nucleotidyltransferase 5A 0.0064903
CDCA3 cell division cycle associated 3 0.00648355
SRSF7 serine/arginine-rich splicing factor 7 0.00647963
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa 0.00645181
SLC35G2 solute carrier family 35, member G2 0.00644352
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.00643916
SUB1 SUB1 homolog (S. cerevisiae) 0.00643176
C8ORF4 chromosome 8 open reading frame 4 0.006424
CCR1 chemokine (C-C motif) receptor 1 0.00640252
SCD5 stearoyl-CoA desaturase 5 0.00640247
KAZN kazrin, periplakin interacting protein 0.00637207
KCTD12 potassium channel tetramerization domain containing 12 0.00635986
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) 0.00635872
PBX1 pre-B-cell leukemia homeobox 1 0.00635499
FOXF1 forkhead box F1 0.00634305
DOCK9 dedicator of cytokinesis 9 0.0063406
SECISBP2 SECIS binding protein 2 0.00631296
ZNF22 zinc finger protein 22 0.00630051
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like 0.00629598
GLCE glucuronic acid epimerase 0.0062932
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 0.00629248
GPC3 glypican 3 0.00628395
WT1 Wilms tumor 1 0.0062715
HNRNPM heterogeneous nuclear ribonucleoprotein M 0.00627114
MED1 mediator complex subunit 1 0.0062695
TNIK TRAF2 and NCK interacting kinase 0.00624603
PDZK1 PDZ domain containing 1 0.00623391
FRY furry homolog (Drosophila) 0.00623201
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9) 0.00623167
CANX calnexin 0.00622611
H2AFV H2A histone family, member V 0.00621834
CTSZ cathepsin Z 0.00618828
NDRG1 N-myc downstream regulated 1 0.00618773
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 0.00617999
MAP3K4 mitogen-activated protein kinase kinase kinase 4 0.00617624
DHRS11 dehydrogenase/reductase (SDR family) member 11 0.00614968
NES nestin 0.00614354
PRNP prion protein 0.00613555
ACACA acetyl-CoA carboxylase alpha 0.00612712
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 0.00612699
GANAB glucosidase, alpha; neutral AB 0.00612666
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) 0.00611159
SEPTIN10 septin 10 0.00609605
EDF1 endothelial differentiation-related factor 1 0.00609391
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 0.00608097
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 0.00608092
MTMR11 myotubularin related protein 11 0.00607454
MSL1 male-specific lethal 1 homolog (Drosophila) 0.00607075
XIC X chromosome inactivation center 0.00607051
CEP43 centrosomal protein 43 0.00606647
BRD2 bromodomain containing 2 0.00604848
SRSF10 serine/arginine-rich splicing factor 10 0.0060291
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 0.00599474
MED17 mediator complex subunit 17 0.00599313
IFI44L interferon-induced protein 44-like 0.00599105
DLG1 discs, large homolog 1 (Drosophila) 0.00596552
YTHDC2 YTH domain containing 2 0.00596461
FZD5 frizzled class receptor 5 0.00595734
TIA1 TIA1 cytotoxic granule-associated RNA binding protein 0.00595507
KCTD14 potassium channel tetramerization domain containing 14 0.00592756
KBTBD11 kelch repeat and BTB (POZ) domain containing 11 0.00592732
EXOC5 exocyst complex component 5 0.00592531
KCNK3 potassium channel, two pore domain subfamily K, member 3 0.00590438
ZNF711 zinc finger protein 711 0.00590122
CLEC2B C-type lectin domain family 2, member B 0.0058989
LIG1 ligase I, DNA, ATP-dependent 0.00589606
DCTN4 dynactin 4 (p62) 0.00589436
KIF18B kinesin family member 18B 0.00589278
DHFR dihydrofolate reductase 0.0058917
SRP72 signal recognition particle 72kDa 0.00589018
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 0.00587659
PLK1 polo-like kinase 1 0.00586265
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 0.00586107
TSPO translocator protein (18kDa) 0.00585436
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) 0.00584579
S100A12 S100 calcium binding protein A12 0.00584551
RSRC2 arginine/serine-rich coiled-coil 2 0.0058347
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.00582051
BMP2 bone morphogenetic protein 2 0.00582031
IQGAP2 IQ motif containing GTPase activating protein 2 0.00579533
COPS7A COP9 signalosome subunit 7A 0.00577597
SREK1 splicing regulatory glutamine/lysine-rich protein 1 0.00575528
FOXM1 forkhead box M1 0.00574945
KANSL2 KAT8 regulatory NSL complex subunit 2 0.00574336
KIF14 kinesin family member 14 0.00573708
TRPM3 transient receptor potential cation channel, subfamily M, member 3 0.00572755
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D 0.0057044
NR4A2 nuclear receptor subfamily 4, group A, member 2 0.00570235
NLGN4X neuroligin 4, X-linked 0.00570127
ZNF83 zinc finger protein 83 0.00568926
ZFC3H1 zinc finger, C3H1-type containing 0.00567627
TMEM45A transmembrane protein 45A 0.00566739
ZNF302 zinc finger protein 302 0.00566018
C7 complement component 7 0.00565705
RAPSN receptor-associated protein of the synapse 0.00564972
UBE2S ubiquitin-conjugating enzyme E2S 0.00564587
RBM39 RNA binding motif protein 39 0.00563873
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.00563777
TLR2 toll-like receptor 2 0.00561943
NANOG Nanog homeobox 0.0056139
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) 0.00560138
GPATCH8 G patch domain containing 8 0.00559254
SRSF5 serine/arginine-rich splicing factor 5 0.00558732
FBXO5 F-box protein 5 0.00558585
APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A 0.00557726
KLF3-AS1 KLF3 antisense RNA 1 0.00556816
PCNA proliferating cell nuclear antigen 0.00556555
CCNL2 cyclin L2 0.00555246
IRAK1 interleukin-1 receptor-associated kinase 1 0.00554897
GSTA4 glutathione S-transferase alpha 4 0.00554759
ARL5A ADP-ribosylation factor-like 5A 0.00554409
ZBTB35 zinc finger and BTB domain containing 35 0.00553881
PRUNE2 prune homolog 2 (Drosophila) 0.00553866
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.00553841
PTP4A3 protein tyrosine phosphatase type IVA, member 3 0.00553426
NDP Norrie disease (pseudoglioma) 0.00553296
GPM6A glycoprotein M6A 0.00552848
CAV1 caveolin 1, caveolae protein, 22kDa 0.00552676
DSTN destrin (actin depolymerizing factor) 0.00551775
COL1A1 collagen, type I, alpha 1 0.00549312

decreased expression

Symbol Name Standardized Value
COG7 component of oligomeric golgi complex 7 -0.0170245
ALCAM activated leukocyte cell adhesion molecule -0.0154364
MSMB microseminoprotein, beta- -0.0142821
CXCL12 chemokine (C-X-C motif) ligand 12 -0.0134206
KRT5 keratin 5, type II -0.0131384
AREG amphiregulin -0.0129089
MT1G metallothionein 1G -0.0127194
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -0.0125338
IFI6 interferon, alpha-inducible protein 6 -0.012516
KRT15 keratin 15, type I -0.0123326
NT5E 5'-nucleotidase, ecto (CD73) -0.0122563
IFI27 interferon, alpha-inducible protein 27 -0.0121508
RAB29 RAB29, member RAS oncogene family -0.0117971
HTRA1 HtrA serine peptidase 1 -0.0111271
DIPK1A divergent protein kinase domain 1A -0.0111251
ADIRF adipogenesis regulatory factor -0.0110064
GREB1 growth regulation by estrogen in breast cancer 1 -0.0109696
THBS2 thrombospondin 2 -0.0108004
LXN latexin -0.0107891
KRT14 keratin 14, type I -0.0107868
GABRP gamma-aminobutyric acid (GABA) A receptor, pi -0.0105151
TFF1 trefoil factor 1 -0.010414
LIMS1 LIM and senescent cell antigen-like domains 1 -0.0102483
C14ORF132 chromosome 14 open reading frame 132 -0.0101763
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme -0.0101294
MT1E metallothionein 1E -0.00997203
IL1R1 interleukin 1 receptor, type I -0.00995812
MT1X metallothionein 1X -0.0098424
MT1F metallothionein 1F -0.00983257
ISG20 interferon stimulated exonuclease gene 20kDa -0.00982993
NUPR1 nuclear protein, transcriptional regulator, 1 -0.00978317
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 -0.00972219
YPEL5 yippee-like 5 (Drosophila) -0.00971671
BLNK B-cell linker -0.00969362
SRPX sushi-repeat containing protein, X-linked -0.00968606
CLEC3B C-type lectin domain family 3, member B -0.00956932
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.00955127
SDC1 syndecan 1 -0.00948607
APOD apolipoprotein D -0.0094217
GADD45A growth arrest and DNA-damage-inducible, alpha -0.00941447
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 -0.00929665
NPC2 Niemann-Pick disease, type C2 -0.00924407
ICA1 islet cell autoantigen 1, 69kDa -0.00924304
CTSD cathepsin D -0.00912555
BASP1 brain abundant, membrane attached signal protein 1 -0.00897397
THBS1 thrombospondin 1 -0.00895814
MXRA7 matrix-remodelling associated 7 -0.00891613
GNAS GNAS complex locus -0.00889434
CDH1 cadherin 1, type 1, E-cadherin (epithelial) -0.00886053
TP53I3 tumor protein p53 inducible protein 3 -0.00880575
TM7SF2 transmembrane 7 superfamily member 2 -0.00880512
INHBA inhibin, beta A -0.00875958
SPRED2 sprouty-related, EVH1 domain containing 2 -0.00874299
SGK1 serum/glucocorticoid regulated kinase 1 -0.00874254
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 -0.00872497
SCGB2A1 secretoglobin, family 2A, member 1 -0.00869003
WISP2 WNT1 inducible signaling pathway protein 2 -0.00868886
FAM171A1 family with sequence similarity 171, member A1 -0.00864665
GPNMB glycoprotein (transmembrane) nmb -0.00860668
RRAS2 related RAS viral (r-ras) oncogene homolog 2 -0.00860616
MLF1 myeloid leukemia factor 1 -0.00854389
ECM1 extracellular matrix protein 1 -0.00852419
SYT17 synaptotagmin XVII -0.00847545
EFHD1 EF-hand domain family, member D1 -0.00847462
ABAT 4-aminobutyrate aminotransferase -0.00846943
MT1HL1 metallothionein 1H-like 1 -0.00846507
CLDN3 claudin 3 -0.00841567
PDGFRA platelet-derived growth factor receptor, alpha polypeptide -0.00841454
ASPN asporin -0.00840416
CCDC176 coiled-coil domain containing 176 -0.0084038
LCN2 lipocalin 2 -0.00839577
OPN3 opsin 3 -0.00838911
UBE2L6 ubiquitin-conjugating enzyme E2L 6 -0.00836146
RRAGD Ras-related GTP binding D -0.00817993
CD9 CD9 molecule -0.008138
ACTA2 actin, alpha 2, smooth muscle, aorta -0.00808683
MME membrane metallo-endopeptidase -0.00807219
MVP major vault protein -0.00806686
HSPA2 heat shock 70kDa protein 2 -0.00805387
TSNAX translin-associated factor X -0.00804393
GPX1 glutathione peroxidase 1 -0.00804389
CREBL2 cAMP responsive element binding protein-like 2 -0.00803582
GDF15 growth differentiation factor 15 -0.00802973
MT1M metallothionein 1M -0.00800645
CLDN7 claudin 7 -0.00799111
FTH1 ferritin, heavy polypeptide 1 -0.00795456
NPIPB3 nuclear pore complex interacting protein family, member B3 -0.00795455
GLUD1 glutamate dehydrogenase 1 -0.0079042
PENK proenkephalin -0.00788033
SFRP4 secreted frizzled-related protein 4 -0.007872
ACP5 acid phosphatase 5, tartrate resistant -0.00786521
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.00783462
MUC5AC mucin 5AC, oligomeric mucus/gel-forming -0.00782481
PHYH phytanoyl-CoA 2-hydroxylase -0.00778625
DLK1 delta-like 1 homolog (Drosophila) -0.00778386
MT1H metallothionein 1H -0.00775844
AMIGO2 adhesion molecule with Ig-like domain 2 -0.00775057
RBM47 RNA binding motif protein 47 -0.00772645
LITAF lipopolysaccharide-induced TNF factor -0.00771791
TSPYL5 TSPY-like 5 -0.00768277
TUBA1A tubulin, alpha 1a -0.00762211
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C -0.00759779
SDC4 syndecan 4 -0.00758439
GPR137B G protein-coupled receptor 137B -0.00757303
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 -0.00754539
IFT27 intraflagellar transport 27 -0.00753051
BCL2A1 BCL2-related protein A1 -0.00752976
SAT1 spermidine/spermine N1-acetyltransferase 1 -0.00751902
GMPR guanosine monophosphate reductase -0.00748342
MLPH melanophilin -0.00747818
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -0.00747622
VTCN1 V-set domain containing T cell activation inhibitor 1 -0.00746789
IPO13 importin 13 -0.00742761
BICC1 BicC family RNA binding protein 1 -0.00742188
PEG10 paternally expressed 10 -0.00741527
UROD uroporphyrinogen decarboxylase -0.0074114
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 -0.00738632
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H -0.00735819
WDR7 WD repeat domain 7 -0.00735718
RGS10 regulator of G-protein signaling 10 -0.0073504
CLMN calmin (calponin-like, transmembrane) -0.00734125
C1ORF54 chromosome 1 open reading frame 54 -0.0073219
LCMT1 leucine carboxyl methyltransferase 1 -0.00728164
KRT81 keratin 81, type II -0.0072753
HSPH1 heat shock 105kDa/110kDa protein 1 -0.00727284
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae) -0.00726352
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A -0.00724508
PRAME preferentially expressed antigen in melanoma -0.00720875
COMP cartilage oligomeric matrix protein -0.007181
DNALI1 dynein, axonemal, light intermediate chain 1 -0.00714742
PRSS8 protease, serine, 8 -0.00711006
EMX2 empty spiracles homeobox 2 -0.00710677
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) -0.00708103
KRT13 keratin 13, type I -0.00707108
CD44 CD44 molecule (Indian blood group) -0.00706999
PROM1 prominin 1 -0.00706353
TPPP3 tubulin polymerization-promoting protein family member 3 -0.0070622
NNMT nicotinamide N-methyltransferase -0.00706178
CRYM crystallin, mu -0.00704467
DDAH1 dimethylarginine dimethylaminohydrolase 1 -0.00700222
IGFBP5 insulin-like growth factor binding protein 5 -0.00699864
LBH limb bud and heart development -0.00699086
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) -0.00695179
SP100 SP100 nuclear antigen -0.00691285
VEGFC vascular endothelial growth factor C -0.00690727
AGTR1 angiotensin II receptor, type 1 -0.00688015
STC2 stanniocalcin 2 -0.00684644
PPP1R7 protein phosphatase 1, regulatory subunit 7 -0.00684638
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain -0.00683968
DCXR dicarbonyl/L-xylulose reductase -0.00683912
TST thiosulfate sulfurtransferase (rhodanese) -0.00682722
MDK midkine (neurite growth-promoting factor 2) -0.00682558
IRF6 interferon regulatory factor 6 -0.00682366
BMP7 bone morphogenetic protein 7 -0.00670182
MINPP1 multiple inositol-polyphosphate phosphatase 1 -0.00669204
IRF9 interferon regulatory factor 9 -0.00668868
LPAR1 lysophosphatidic acid receptor 1 -0.00667148
COA3 cytochrome c oxidase assembly factor 3 -0.00666495
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 -0.00660711
PALLD palladin, cytoskeletal associated protein -0.00659375
CES1 carboxylesterase 1 -0.00658908
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene -0.00658452
CAST calpastatin -0.0065799
ARMCX1 armadillo repeat containing, X-linked 1 -0.00654286
TNNT1 troponin T type 1 (skeletal, slow) -0.00654274
GSTM3 glutathione S-transferase mu 3 (brain) -0.00654223
GEM GTP binding protein overexpressed in skeletal muscle -0.00652421
GPX4 glutathione peroxidase 4 -0.0065089
PDGFRL platelet-derived growth factor receptor-like -0.00650251
MFAP5 microfibrillar associated protein 5 -0.0064954
IL1RN interleukin 1 receptor antagonist -0.00649184
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 -0.00648442
MYB v-myb avian myeloblastosis viral oncogene homolog -0.0064743
GNG11 guanine nucleotide binding protein (G protein), gamma 11 -0.00646115
C3ORF14 chromosome 3 open reading frame 14 -0.00645789
SUGCT succinyl-CoA:glutarate-CoA transferase -0.00644543
ALDH3B1 aldehyde dehydrogenase 3 family, member B1 -0.0064449
MNAT1 MNAT CDK-activating kinase assembly factor 1 -0.00643402
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 -0.00640123
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) -0.00640092
ASXL2 additional sex combs like transcriptional regulator 2 -0.00639308
BPIFA1 BPI fold containing family A, member 1 -0.00637547
NANS N-acetylneuraminic acid synthase -0.00636169
PTP4A1 protein tyrosine phosphatase type IVA, member 1 -0.00635646
KYNU kynureninase -0.00635645
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide -0.00635552
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 -0.00634322
SWAP70 SWAP switching B-cell complex 70kDa subunit -0.00633286
IL1B interleukin 1, beta -0.00632608
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) -0.00632071
SURF1 surfeit 1 -0.00629397
CEL carboxyl ester lipase -0.00629276
CYB5R1 cytochrome b5 reductase 1 -0.00629144
SH3BGR SH3 domain binding glutamate-rich protein -0.00626852
FOS FBJ murine osteosarcoma viral oncogene homolog -0.00626804
COCH cochlin -0.00625889
ACTN1 actinin, alpha 1 -0.00624546
CNN1 calponin 1, basic, smooth muscle -0.00623181
DAXX death-domain associated protein -0.0062244
ACVR2A activin A receptor, type IIA -0.00620914
EIF5A eukaryotic translation initiation factor 5A -0.00618282
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 -0.00616453
RRAGC Ras-related GTP binding C -0.00616334
COPG1 coatomer protein complex, subunit gamma 1 -0.00616028
ADD3 adducin 3 (gamma) -0.00615817
TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa -0.0061564
CTSS cathepsin S -0.00615064
AVPI1 arginine vasopressin-induced 1 -0.00613113
TBPL1 TBP-like 1 -0.00612962
CSTA cystatin A (stefin A) -0.00612121
EXOSC4 exosome component 4 -0.00611818
DCN decorin -0.00609338
ZFP36L2 ZFP36 ring finger protein-like 2 -0.0060812
PXDC1 PX domain containing 1 -0.00607472
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.00606915
LRRC15 leucine rich repeat containing 15 -0.0060666
GALC galactosylceramidase -0.00606153
ERLIN2 ER lipid raft associated 2 -0.00605519
PBLD phenazine biosynthesis-like protein domain containing -0.006053
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -0.00605243
ECI2 enoyl-CoA delta isomerase 2 -0.00605239
NEU1 sialidase 1 (lysosomal sialidase) -0.00602088
HSPB11 heat shock protein family B (small), member 11 -0.00599528
POPDC3 popeye domain containing 3 -0.0059942
EAF2 ELL associated factor 2 -0.00599337
ZDHHC4 zinc finger, DHHC-type containing 4 -0.00599202
FAM114A1 family with sequence similarity 114, member A1 -0.00598536
FUCA1 fucosidase, alpha-L- 1, tissue -0.00598397
SNX3 sorting nexin 3 -0.0059829
TRIM8 tripartite motif containing 8 -0.00596211
GPD1L glycerol-3-phosphate dehydrogenase 1-like -0.00594067
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor -0.00593958
CD79B CD79b molecule, immunoglobulin-associated beta -0.00593646
PIGR polymeric immunoglobulin receptor -0.00592107
IQCG IQ motif containing G -0.00591572
CRELD2 cysteine-rich with EGF-like domains 2 -0.00590678
TFPI2 tissue factor pathway inhibitor 2 -0.00587663
GAS6 growth arrest-specific 6 -0.00586102
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 -0.0058608
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 -0.00585634
WBP1L WW domain binding protein 1-like -0.00584685
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) -0.00583835
SQOR sulfide quinone oxidoreductase -0.00583109
CRABP1 cellular retinoic acid binding protein 1 -0.00582352
ADCY1 adenylate cyclase 1 (brain) -0.00581128
SPATS2 spermatogenesis associated, serine-rich 2 -0.00579997
UBFD1 ubiquitin family domain containing 1 -0.00579307
LOXL1 lysyl oxidase-like 1 -0.00577698
DNAAF1 dynein, axonemal, assembly factor 1 -0.00577558
PERP PERP, TP53 apoptosis effector -0.00575967