NDUFAF1 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description NADH dehydrogenase (ubiquinone) complex I, assembly factor 1|This gene encodes a complex I assembly factor protein. Complex I (NADH-ubiquinone oxidoreductase) catalyzes the transfer of electrons from NADH to ubiquinone (coenzyme Q) in the first step of the mitochondrial respiratory chain, resulting in the translocation of protons across the inner mitochondrial membrane. The encoded protein is required for assembly of complex I, and mutations in this gene are a cause of mitochondrial complex I deficiency. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 19. [provided by RefSeq, Dec 2011] (NCBI Entrez Gene Database, 51103)
External Link http://www.ncbi.nlm.nih.gov/gene/51103
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Genes

38 interacting proteins for NDUFAF1 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
CMC1 C-x(9)-C motif containing 1
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)
COA3 cytochrome c oxidase assembly factor 3
COX11 COX11 cytochrome c oxidase copper chaperone
COX14 COX14 cytochrome c oxidase assembly factor
COX15 cytochrome c oxidase assembly homolog 15 (yeast)
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae)
COX4I1 cytochrome c oxidase subunit IV isoform 1
COX5A cytochrome c oxidase subunit Va
COX6C cytochrome c oxidase subunit VIc
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
ECSIT ECSIT signalling integrator
MAGEA11 melanoma antigen family A11
MAVS mitochondrial antiviral signaling protein
NDUFA6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa
NDUFA9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa
NDUFC2 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)
NDUFS5 NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase)
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
OCIAD2 OCIA domain containing 2
OMA1 OMA1 zinc metallopeptidase
PNKD paroxysmal nonkinesigenic dyskinesia
RDH13 retinol dehydrogenase 13 (all-trans/9-cis)
SFXN1 sideroflexin 1
SFXN4 sideroflexin 4
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
SMIM20 small integral membrane protein 20
SURF1 surfeit 1
TIMM21 translocase of inner mitochondrial membrane 21 homolog (yeast)
TIMMDC1 translocase of inner mitochondrial membrane domain containing 1
TMEM177 transmembrane protein 177
TMEM223 transmembrane protein 223
TMEM70 transmembrane protein 70