NEDD8 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description neural precursor cell expressed, developmentally down-regulated 8| (NCBI Entrez Gene Database, 4738)
External Link https://ncbi.nlm.nih.gov/gene/4738
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Genes

498 genes differentially expressed following the NEDD8 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.0140362
LTF lactotransferrin 0.0126159
S100A9 S100 calcium binding protein A9 0.0115462
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.0108598
BMP4 bone morphogenetic protein 4 0.0104239
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.00966644
NIBAN1 niban apoptosis regulator 1 0.00910719
GCLM glutamate-cysteine ligase, modifier subunit 0.0087437
S100P S100 calcium binding protein P 0.00866358
HSPA1A heat shock 70kDa protein 1A 0.00852958
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.00851755
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 0.00844622
S100A8 S100 calcium binding protein A8 0.00839863
ACSL1 acyl-CoA synthetase long-chain family member 1 0.00835278
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 0.00810383
PMM2 phosphomannomutase 2 0.00810048
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 0.00808882
LCN2 lipocalin 2 0.00804248
AKR1C1 aldo-keto reductase family 1, member C1 0.0079357
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.00792171
KRT15 keratin 15, type I 0.00789422
BAG3 BCL2-associated athanogene 3 0.00784531
PLK1 polo-like kinase 1 0.00784159
NQO1 NAD(P)H dehydrogenase, quinone 1 0.00782129
TACSTD2 tumor-associated calcium signal transducer 2 0.00779
MGP matrix Gla protein 0.00777756
PDZK1IP1 PDZK1 interacting protein 1 0.00772726
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 0.00767649
AKR1C2 aldo-keto reductase family 1, member C2 0.00766998
SRGN serglycin 0.00755736
CD44 CD44 molecule (Indian blood group) 0.00751049
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 0.0075052
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.00743202
CTSG cathepsin G 0.00719819
CTSH cathepsin H 0.0071707
AKAP12 A kinase (PRKA) anchor protein 12 0.00714036
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 0.00711415
LYZ lysozyme 0.00711028
CFI complement factor I 0.00696548
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 0.00690566
HSPH1 heat shock 105kDa/110kDa protein 1 0.00678614
HOPX HOP homeobox 0.00677356
C7 complement component 7 0.00677354
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 0.00675069
NID1 nidogen 1 0.00658663
C1S complement component 1, s subcomponent 0.00654637
RAB5IF RAB5 interacting factor 0.00642809
C1R complement component 1, r subcomponent 0.00630471
UGDH UDP-glucose 6-dehydrogenase 0.00626968
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 0.00621372
CHI3L2 chitinase 3-like 2 0.00620225
TXNRD1 thioredoxin reductase 1 0.00616968
CXCL8 chemokine (C-X-C motif) ligand 8 0.00615724
CLEC2B C-type lectin domain family 2, member B 0.00614659
FGG fibrinogen gamma chain 0.00612523
GCLC glutamate-cysteine ligase, catalytic subunit 0.0060866
KRT81 keratin 81, type II 0.00597426
AQP3 aquaporin 3 (Gill blood group) 0.00595864
ZEB1 zinc finger E-box binding homeobox 1 0.00595773
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 0.00595635
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic 0.00594387
MYBPC1 myosin binding protein C, slow type 0.00593283
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.00589644
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 0.00584347
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 0.00580475
STOM stomatin 0.00578954
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 0.00576469
ASPH aspartate beta-hydroxylase 0.00575474
HSPE1 heat shock 10kDa protein 1 0.00572283
G0S2 G0/G1 switch 2 0.00569254
NUSAP1 nucleolar and spindle associated protein 1 0.00568816
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.0056828
AKR1C3 aldo-keto reductase family 1, member C3 0.00568193
TALDO1 transaldolase 1 0.0056805
CNTN1 contactin 1 0.00567296
ZNF281 zinc finger protein 281 0.00566674
ANXA1 annexin A1 0.00563143
ADM adrenomedullin 0.00558985
SLPI secretory leukocyte peptidase inhibitor 0.00558243
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.00557837
TUBA4A tubulin, alpha 4a 0.00557772
VWF von Willebrand factor 0.0055683
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.00555717
INAVA innate immunity activator 0.00554168
SOAT1 sterol O-acyltransferase 1 0.00552839
TM4SF1 transmembrane 4 L six family member 1 0.00552711
CNOT4 CCR4-NOT transcription complex, subunit 4 0.00550416
KCTD12 potassium channel tetramerization domain containing 12 0.00545808
ORM1 orosomucoid 1 0.00543748
MMP7 matrix metallopeptidase 7 0.00543519
RTN2 reticulon 2 0.00536187
ABLIM1 actin binding LIM protein 1 0.00534648
SCGB2A2 secretoglobin, family 2A, member 2 0.00534248
PDZD8 PDZ domain containing 8 0.00530845
ZFPM2 zinc finger protein, FOG family member 2 0.00529802
DLK1 delta-like 1 homolog (Drosophila) 0.00524538
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.00519229
ACSL4 acyl-CoA synthetase long-chain family member 4 0.00516834
NELL2 NEL-like 2 (chicken) 0.00513903
ALOX5AP arachidonate 5-lipoxygenase-activating protein 0.00512345
ENC1 ectodermal-neural cortex 1 (with BTB domain) 0.0051114
CD93 CD93 molecule 0.00505439
TGFBR3 transforming growth factor, beta receptor III 0.00502943
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 0.00501074
NOP16 NOP16 nucleolar protein 0.00499399
JPT1 Jupiter microtubule associated homolog 1 0.00499131
FABP4 fatty acid binding protein 4, adipocyte 0.00498648
GBP1 guanylate binding protein 1, interferon-inducible 0.00497565
MICB MHC class I polypeptide-related sequence B 0.00495564
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 0.00495493
RBM26 RNA binding motif protein 26 0.00493838
SLC12A8 solute carrier family 12, member 8 0.0049158
HBEGF heparin-binding EGF-like growth factor 0.00491419
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.00490088
KCTD9 potassium channel tetramerization domain containing 9 0.00489194
TMEM165 transmembrane protein 165 0.00487808
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.00487753
KYNU kynureninase 0.00485435
RPS4Y1 ribosomal protein S4, Y-linked 1 0.00484214
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 0.00481659
DDR2 discoidin domain receptor tyrosine kinase 2 0.00481601
DRAM1 DNA-damage regulated autophagy modulator 1 0.00479937
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.0047713
ITGAV integrin, alpha V 0.00476618
AKAP8 A kinase (PRKA) anchor protein 8 0.00476599
AMPH amphiphysin 0.00476387
RGS2 regulator of G-protein signaling 2 0.00475503
CD99 CD99 molecule 0.00475284
GOLM1 golgi membrane protein 1 0.00475182
GUCY2C guanylate cyclase 2C 0.00475123
SRPX sushi-repeat containing protein, X-linked 0.00474878
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 0.00474778
FXYD5 FXYD domain containing ion transport regulator 5 0.00472549
WIF1 WNT inhibitory factor 1 0.00469426
CCDC86 coiled-coil domain containing 86 0.00467362
SPARCL1 SPARC-like 1 (hevin) 0.00465085
TLCD3A TLC domain containing 3A 0.00464327
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.00461718
RGCC regulator of cell cycle 0.00461351
GTPBP4 GTP binding protein 4 0.00460962
GSDME gasdermin E 0.00458131
PIR pirin (iron-binding nuclear protein) 0.00457705
PMP22 peripheral myelin protein 22 0.00456293
IGHMBP2 immunoglobulin mu binding protein 2 0.00455161
C3 complement component 3 0.0045396
RAPSN receptor-associated protein of the synapse 0.00453651
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 0.00452792
CKAP4 cytoskeleton-associated protein 4 0.00451615
FN1 fibronectin 1 0.0045067
CXCR4 chemokine (C-X-C motif) receptor 4 0.00449994
DBN1 drebrin 1 0.0044963
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 0.00448375
SFRP1 secreted frizzled-related protein 1 0.00448084
TRIM16 tripartite motif containing 16 0.00446208
LAMB3 laminin, beta 3 0.00446168
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.00445914
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 0.00444568
DCHS1 dachsous cadherin-related 1 0.00444307
CSTA cystatin A (stefin A) 0.00444158
CORO1A coronin, actin binding protein, 1A 0.00443975
CCNA1 cyclin A1 0.00442458
MTUS1 microtubule associated tumor suppressor 1 0.00441507
ADAT1 adenosine deaminase, tRNA-specific 1 0.00441054
RRM2 ribonucleotide reductase M2 0.00440941
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3 0.00440585
ATF3 activating transcription factor 3 0.00439662
SUSD5 sushi domain containing 5 0.00438097
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.00435039
TPX2 TPX2, microtubule-associated 0.00434927
NKX3-1 NK3 homeobox 1 0.00433935
KRT23 keratin 23, type I 0.00432717
CCNA2 cyclin A2 0.00427277
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 0.00426401
GRK5 G protein-coupled receptor kinase 5 0.00426285
CALML5 calmodulin-like 5 0.004257
FHOD3 formin homology 2 domain containing 3 0.00424275
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.00424224
FSCN1 fascin actin-bundling protein 1 0.0042357
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.00423017
MEIS2 Meis homeobox 2 0.00422493
EIF3J eukaryotic translation initiation factor 3, subunit J 0.00421571
MSX1 msh homeobox 1 0.00418768
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 0.00418369
SQLE squalene epoxidase 0.00416689
KPNA3 karyopherin alpha 3 (importin alpha 4) 0.00416326
CCL20 chemokine (C-C motif) ligand 20 0.00415626
CNOT6 CCR4-NOT transcription complex, subunit 6 0.00414541
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 0.00414251
LRP4 low density lipoprotein receptor-related protein 4 0.00413876
MRPL9 mitochondrial ribosomal protein L9 0.00413229
KPNB1 karyopherin (importin) beta 1 0.00413131
MBD2 methyl-CpG binding domain protein 2 0.004115
GIMAP6 GTPase, IMAP family member 6 0.00410474
PTPRM protein tyrosine phosphatase, receptor type, M 0.00410253
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.00409625
LMO2 LIM domain only 2 (rhombotin-like 1) 0.00408421
LAPTM4B lysosomal protein transmembrane 4 beta 0.00408381
UBAP2 ubiquitin associated protein 2 0.00407421
S100A11 S100 calcium binding protein A11 0.00407146
CACYBP calcyclin binding protein 0.00407018
FNDC3B fibronectin type III domain containing 3B 0.00406068
DCN decorin 0.00406055
HMGA1 high mobility group AT-hook 1 0.00405083
GIMAP4 GTPase, IMAP family member 4 0.0040465
SHCBP1 SHC SH2-domain binding protein 1 0.00404366
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.00403567
PELI1 pellino E3 ubiquitin protein ligase 1 0.00403498
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32 0.00403375
GPATCH8 G patch domain containing 8 0.0040272
NUP58 nucleoporin 58 0.00402041
PRAME preferentially expressed antigen in melanoma 0.00400761
TGFB1 transforming growth factor, beta 1 0.00400603
DOCK9 dedicator of cytokinesis 9 0.00399947
MPZL2 myelin protein zero-like 2 0.00399918
RRM1 ribonucleotide reductase M1 0.00397814
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 0.00397652
PLTP phospholipid transfer protein 0.00397381
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.00396177
LTB lymphotoxin beta (TNF superfamily, member 3) 0.00396086
TBC1D4 TBC1 domain family, member 4 0.0039539
PLAA phospholipase A2-activating protein 0.00395224
MSMO1 methylsterol monooxygenase 1 0.00395222
ATAD2 ATPase family, AAA domain containing 2 0.00395148
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) 0.0039392
PALMD palmdelphin 0.00393716
SRPK1 SRSF protein kinase 1 0.00393308
EMP1 epithelial membrane protein 1 0.00393194
MGLL monoglyceride lipase 0.00392971
CALML3 calmodulin-like 3 0.00392044
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 0.0039174
S100A7 S100 calcium binding protein A7 0.00391719
MYO1C myosin IC 0.00391542
NINJ1 ninjurin 1 0.00391305
CREB3L2 cAMP responsive element binding protein 3-like 2 0.00391057
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.0039086
CAMP cathelicidin antimicrobial peptide 0.00390621
ABHD6 abhydrolase domain containing 6 0.0038979
ELF1 E74-like factor 1 (ets domain transcription factor) 0.00389473
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.00388785
IL15RA interleukin 15 receptor, alpha 0.0038849
LPAR6 lysophosphatidic acid receptor 6 0.00388405
G6PD glucose-6-phosphate dehydrogenase 0.00387705
RSL1D1 ribosomal L1 domain containing 1 0.00387525
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.00387324
GPX3 glutathione peroxidase 3 0.00386803
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 0.00386465
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 0.00384809
PDGFC platelet derived growth factor C 0.00384286
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 0.00383671
TRIM14 tripartite motif containing 14 0.00383619

decreased expression

Symbol Name Standardized Value
MAP7 microtubule-associated protein 7 -0.016563
CDH1 cadherin 1, type 1, E-cadherin (epithelial) -0.00910436
BANK1 B-cell scaffold protein with ankyrin repeats 1 -0.00811485
PAN2 PAN2 poly(A) specific ribonuclease subunit -0.00808877
TFF1 trefoil factor 1 -0.0077178
BHLHE41 basic helix-loop-helix family, member e41 -0.0076089
KRT19 keratin 19, type I -0.00756239
GPNMB glycoprotein (transmembrane) nmb -0.00724953
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -0.00714374
TSPAN13 tetraspanin 13 -0.00704827
ASS1 argininosuccinate synthase 1 -0.00679717
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) -0.00674284
ADIRF adipogenesis regulatory factor -0.0066933
TXNIP thioredoxin interacting protein -0.00664398
KRT8 keratin 8, type II -0.00656368
EMX2 empty spiracles homeobox 2 -0.00655495
ZSCAN18 zinc finger and SCAN domain containing 18 -0.00654078
GSTZ1 glutathione S-transferase zeta 1 -0.00644581
METTL7A methyltransferase like 7A -0.00640924
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 -0.00626151
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 -0.00610952
ZDHHC11 zinc finger, DHHC-type containing 11 -0.00610791
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 -0.00603209
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) -0.00598896
CD9 CD9 molecule -0.00588099
ICA1 islet cell autoantigen 1, 69kDa -0.00587351
SH3GLB2 SH3-domain GRB2-like endophilin B2 -0.00579859
CPB1 carboxypeptidase B1 (tissue) -0.00578248
DMAC2L distal membrane arm assembly component 2 like -0.0057124
WDTC1 WD and tetratricopeptide repeats 1 -0.00571168
ALDH6A1 aldehyde dehydrogenase 6 family, member A1 -0.00567508
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 -0.00567491
TUBB2B tubulin, beta 2B class IIb -0.0056629
MAN1A1 mannosidase, alpha, class 1A, member 1 -0.00561943
MAGEA3 melanoma antigen family A3 -0.00557894
ZDHHC4 zinc finger, DHHC-type containing 4 -0.00555066
MYB v-myb avian myeloblastosis viral oncogene homolog -0.00551277
TRIB2 tribbles pseudokinase 2 -0.00550471
GSDMB gasdermin B -0.00548674
CRIP1 cysteine-rich protein 1 (intestinal) -0.00548388
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -0.00545199
SPATA20 spermatogenesis associated 20 -0.00545019
BTBD3 BTB (POZ) domain containing 3 -0.0054476
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -0.00544756
TMEM260 transmembrane protein 260 -0.00543526
PDK4 pyruvate dehydrogenase kinase, isozyme 4 -0.00543202
FKBP11 FK506 binding protein 11, 19 kDa -0.00540265
CREBL2 cAMP responsive element binding protein-like 2 -0.00536416
GAS1 growth arrest-specific 1 -0.00535361
ASCL1 achaete-scute family bHLH transcription factor 1 -0.00535115
IRX5 iroquois homeobox 5 -0.00534014
AGR2 anterior gradient 2 -0.00531379
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -0.00530455
SGPP1 sphingosine-1-phosphate phosphatase 1 -0.00528942
COL11A1 collagen, type XI, alpha 1 -0.00527107
NEK9 NIMA-related kinase 9 -0.00522768
MUC2 mucin 2, oligomeric mucus/gel-forming -0.00517803
PFKL phosphofructokinase, liver -0.0051033
GSN gelsolin -0.00509236
ACTR10 actin-related protein 10 homolog (S. cerevisiae) -0.00508656
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 -0.00508126
CCNG2 cyclin G2 -0.00507464
PCCA propionyl CoA carboxylase, alpha polypeptide -0.00505108
HMGB3 high mobility group box 3 -0.00505095
BTK Bruton agammaglobulinemia tyrosine kinase -0.00502745
TMEM106C transmembrane protein 106C -0.00502245
FKBP3 FK506 binding protein 3, 25kDa -0.00498222
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 -0.00497816
PAEP progestagen-associated endometrial protein -0.0049745
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A -0.00496882
PEG10 paternally expressed 10 -0.00495395
SIX1 SIX homeobox 1 -0.00495002
SPINK4 serine peptidase inhibitor, Kazal type 4 -0.00494866
MNAT1 MNAT CDK-activating kinase assembly factor 1 -0.00494347
TMEM230 transmembrane protein 230 -0.0049375
MYO1D myosin ID -0.0049321
RPA3 replication protein A3, 14kDa -0.00492395
SYNE3 spectrin repeat containing, nuclear envelope family member 3 -0.00490332
DALRD3 DALR anticodon binding domain containing 3 -0.00489976
CCDC176 coiled-coil domain containing 176 -0.00489241
PON2 paraoxonase 2 -0.00489112
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 -0.00488573
ADAM10 ADAM metallopeptidase domain 10 -0.00488011
TM7SF2 transmembrane 7 superfamily member 2 -0.00484753
NPC2 Niemann-Pick disease, type C2 -0.00484529
NME3 NME/NM23 nucleoside diphosphate kinase 3 -0.00483373
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 -0.00479433
PXMP2 peroxisomal membrane protein 2, 22kDa -0.00477791
HMGN3 high mobility group nucleosomal binding domain 3 -0.00477363
POLG2 polymerase (DNA directed), gamma 2, accessory subunit -0.00477173
ACYP1 acylphosphatase 1, erythrocyte (common) type -0.00475526
ERBB2 erb-b2 receptor tyrosine kinase 2 -0.00475115
KIAA0226L KIAA0226-like -0.00474487
RRAGA Ras-related GTP binding A -0.00474219
GAS6 growth arrest-specific 6 -0.00473345
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -0.00471737
EFHC1 EF-hand domain (C-terminal) containing 1 -0.00471448
ITM2C integral membrane protein 2C -0.00471098
CYFIP2 cytoplasmic FMR1 interacting protein 2 -0.00471021
BLNK B-cell linker -0.00470592
NBPF10 neuroblastoma breakpoint family, member 10 -0.00470529
EFCAB11 EF-hand calcium binding domain 11 -0.00470417
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae) -0.00470206
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 -0.00469987
MMP3 matrix metallopeptidase 3 -0.00469297
APOLD1 apolipoprotein L domain containing 1 -0.00469251
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) -0.00468438
MYO5C myosin VC -0.00468308
SPINT2 serine peptidase inhibitor, Kunitz type, 2 -0.00468148
FOXG1 forkhead box G1 -0.00466641
RABAC1 Rab acceptor 1 (prenylated) -0.00465016
CHMP4A charged multivesicular body protein 4A -0.00464411
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 -0.00463871
TSPAN12 tetraspanin 12 -0.00463861
ACKR3 atypical chemokine receptor 3 -0.00463518
BCAT2 branched chain amino-acid transaminase 2, mitochondrial -0.00460586
TCF4 transcription factor 4 -0.00458202
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 -0.00457788
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa -0.00456406
MLPH melanophilin -0.00456138
CDK5RAP3 CDK5 regulatory subunit associated protein 3 -0.00455988
ZNF226 zinc finger protein 226 -0.00455702
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein -0.00455516
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 -0.00452582
REG3A regenerating islet-derived 3 alpha -0.00451469
ADAM28 ADAM metallopeptidase domain 28 -0.0044845
CPVL carboxypeptidase, vitellogenic-like -0.00447963
PAAF1 proteasomal ATPase-associated factor 1 -0.00446319
DDAH1 dimethylarginine dimethylaminohydrolase 1 -0.00443721
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C -0.00443718
BCHE butyrylcholinesterase -0.00443013
MBL2 mannose-binding lectin (protein C) 2, soluble -0.00442422
STX8 syntaxin 8 -0.00441269
LDOC1 leucine zipper, down-regulated in cancer 1 -0.00439808
MOK MOK protein kinase -0.00439644
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7 -0.00439338
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -0.00438698
TKTL1 transketolase-like 1 -0.00438696
DNAAF2 dynein, axonemal, assembly factor 2 -0.00437955
KRT18 keratin 18, type I -0.00437196
COMP cartilage oligomeric matrix protein -0.00436471
HSPA2 heat shock 70kDa protein 2 -0.00436339
LAMA5 laminin, alpha 5 -0.00435298
RIPOR2 RHO family interacting cell polarization regulator 2 -0.00434665
EPCAM epithelial cell adhesion molecule -0.00434549
GALC galactosylceramidase -0.00434449
TNS3 tensin 3 -0.00433944
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.00432555
SIPA1L1 signal-induced proliferation-associated 1 like 1 -0.00431822
AK1 adenylate kinase 1 -0.00431024
DAZAP2 DAZ associated protein 2 -0.00430049
P2RY14 purinergic receptor P2Y, G-protein coupled, 14 -0.00430031
ASXL2 additional sex combs like transcriptional regulator 2 -0.00429338
TCL1A T-cell leukemia/lymphoma 1A -0.00428691
CTBP2 C-terminal binding protein 2 -0.0042869
CDR1 cerebellar degeneration-related protein 1, 34kDa -0.00426321
REG1A regenerating islet-derived 1 alpha -0.00426194
NDUFB1 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa -0.00426072
WDR45 WD repeat domain 45 -0.00425382
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase -0.00424308
COG7 component of oligomeric golgi complex 7 -0.00422471
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2 -0.00422351
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa -0.00421561
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 -0.00420726
RNPS1 RNA binding protein S1, serine-rich domain -0.00420234
ERH enhancer of rudimentary homolog (Drosophila) -0.00418471
ZNF91 zinc finger protein 91 -0.00417568
DACH1 dachshund family transcription factor 1 -0.00417503
CPA3 carboxypeptidase A3 (mast cell) -0.00417088
DEPTOR DEP domain containing MTOR-interacting protein -0.0041647
LETMD1 LETM1 domain containing 1 -0.00416431
CLDN3 claudin 3 -0.00416305
GOLGA8H golgin A8 family, member H -0.00413982
PAIP2B poly(A) binding protein interacting protein 2B -0.00413496
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) -0.00413431
GPD1L glycerol-3-phosphate dehydrogenase 1-like -0.00412653
CYBA cytochrome b-245, alpha polypeptide -0.00412462
IRF4 interferon regulatory factor 4 -0.00411338
LLGL2 lethal giant larvae homolog 2 (Drosophila) -0.00410474
ERLIN2 ER lipid raft associated 2 -0.0041018
CTSK cathepsin K -0.00410101
H2AFJ H2A histone family, member J -0.00408815
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) -0.00408677
DKFZP586I1420 uncharacterized protein DKFZp586I1420 -0.00408599
COG5 component of oligomeric golgi complex 5 -0.00408395
FCGRT Fc fragment of IgG, receptor, transporter, alpha -0.00407455
VTI1B vesicle transport through interaction with t-SNAREs 1B -0.00407431
B9D1 B9 protein domain 1 -0.00407277
REPIN1 replication initiator 1 -0.00405101
FAM13A family with sequence similarity 13, member A -0.00404285
CHKB choline kinase beta -0.00402769
GSE1 Gse1 coiled-coil protein -0.00402512
CHN2 chimerin 2 -0.00402151
GREM1 gremlin 1, DAN family BMP antagonist -0.00401515
DHRS2 dehydrogenase/reductase (SDR family) member 2 -0.00401378
NSUN5P1 NOP2/Sun domain family, member 5 pseudogene 1 -0.0040119
SKAP2 src kinase associated phosphoprotein 2 -0.00400781
C5ORF30 chromosome 5 open reading frame 30 -0.00400366
MLH3 mutL homolog 3 -0.0040032
PHYH phytanoyl-CoA 2-hydroxylase -0.00399896
HCRT hypocretin (orexin) neuropeptide precursor -0.00399537
CPE carboxypeptidase E -0.00399082
XIC X chromosome inactivation center -0.00398773
MAGED1 melanoma antigen family D1 -0.00398516
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog -0.00398069
GTF2I general transcription factor IIi -0.00397216
LGALS3 lectin, galactoside-binding, soluble, 3 -0.00396792
S100A4 S100 calcium binding protein A4 -0.0039658
SYNRG synergin, gamma -0.00396577
ACTB actin, beta -0.00394268
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15 -0.00393876
KIF1A kinesin family member 1A -0.00393306
TWIST1 twist family bHLH transcription factor 1 -0.00391934
MAGED2 melanoma antigen family D2 -0.00390964
ZNF331 zinc finger protein 331 -0.00390255
LXN latexin -0.00389975
OPN3 opsin 3 -0.00388329
HSBP1 heat shock factor binding protein 1 -0.00386132
BEX1 brain expressed, X-linked 1 -0.0038613
ACAA2 acetyl-CoA acyltransferase 2 -0.0038595
TST thiosulfate sulfurtransferase (rhodanese) -0.00385697
DNALI1 dynein, axonemal, light intermediate chain 1 -0.00385535
ZNF410 zinc finger protein 410 -0.00384494
BUD31 BUD31 homolog (S. cerevisiae) -0.00384471
IRS2 insulin receptor substrate 2 -0.00384289
GPX1 glutathione peroxidase 1 -0.0038423
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 -0.00383652
ITPK1 inositol-tetrakisphosphate 1-kinase -0.00382259
ZMIZ1 zinc finger, MIZ-type containing 1 -0.00382241
LMBRD1 LMBR1 domain containing 1 -0.00381665
AMZ2 archaelysin family metallopeptidase 2 -0.00381217
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -0.00381057
QPCT glutaminyl-peptide cyclotransferase -0.00380746
BMP7 bone morphogenetic protein 7 -0.00380185
HOXC10 homeobox C10 -0.00379779
SESN1 sestrin 1 -0.0037875
PCDH9 protocadherin 9 -0.0037872
TRIP6 thyroid hormone receptor interactor 6 -0.00378647
PFDN5 prefoldin subunit 5 -0.00378097
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -0.00377785
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) -0.00376332
DUSP3 dual specificity phosphatase 3 -0.0037601
SLC38A2 solute carrier family 38, member 2 -0.00375517
COPS6 COP9 signalosome subunit 6 -0.00375279
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) -0.0037489
EHF ets homologous factor -0.00374419
SURF1 surfeit 1 -0.00373441
IFT122 intraflagellar transport 122 -0.00373434