NEK6 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description NIMA-related kinase 6|The protein encoded by this gene is a kinase required for progression through the metaphase portion of mitosis. Inhibition of the encoded protein can lead to apoptosis. This protein also can enhance tumorigenesis by suppressing tumor cell senescence. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] (NCBI Entrez Gene Database, 10783)
External Link https://ncbi.nlm.nih.gov/gene/10783
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Genes

499 genes differentially expressed following the NEK6 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
SCGB2A1 secretoglobin, family 2A, member 1 0.0128315
CXADR coxsackie virus and adenovirus receptor 0.0109896
MAGEA3 melanoma antigen family A3 0.0105334
SPRR1B small proline-rich protein 1B 0.0102333
RIPK4 receptor-interacting serine-threonine kinase 4 0.010028
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.00997373
S100A9 S100 calcium binding protein A9 0.00985542
ADAM10 ADAM metallopeptidase domain 10 0.00975123
DEFB1 defensin, beta 1 0.00970167
CSTA cystatin A (stefin A) 0.00965361
APOA2 apolipoprotein A-II 0.00954886
MSX1 msh homeobox 1 0.00954087
KRT6A keratin 6A, type II 0.0092902
NCK1 NCK adaptor protein 1 0.00918577
SPINK5 serine peptidase inhibitor, Kazal type 5 0.00896832
TM4SF1 transmembrane 4 L six family member 1 0.00874825
NRN1 neuritin 1 0.00862931
GNAS GNAS complex locus 0.00846606
KRT5 keratin 5, type II 0.00838748
F2RL1 coagulation factor II (thrombin) receptor-like 1 0.00832241
MT1E metallothionein 1E 0.00821288
EXT1 exostosin glycosyltransferase 1 0.00814511
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.00813845
S100A8 S100 calcium binding protein A8 0.0079381
AGPS alkylglycerone phosphate synthase 0.00793767
SLPI secretory leukocyte peptidase inhibitor 0.00793475
MYO1B myosin IB 0.00783363
AHSG alpha-2-HS-glycoprotein 0.00780803
S100A14 S100 calcium binding protein A14 0.00779787
HSPA1A heat shock 70kDa protein 1A 0.00776688
KRT6B keratin 6B, type II 0.00774056
PPL periplakin 0.0074999
KYNU kynureninase 0.00747982
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 0.00744496
EPB41L4B erythrocyte membrane protein band 4.1 like 4B 0.00739093
KLK10 kallikrein-related peptidase 10 0.00738745
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 0.00732204
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.00728363
APOA1 apolipoprotein A-I 0.0072806
APOB apolipoprotein B 0.00727086
TTR transthyretin 0.00726945
CLCA4 chloride channel accessory 4 0.00726111
DUSP2 dual specificity phosphatase 2 0.00725611
EMP1 epithelial membrane protein 1 0.00719099
FOLR1 folate receptor 1 (adult) 0.00718441
NDC1 NDC1 transmembrane nucleoporin 0.00707172
RPS5 ribosomal protein S5 0.00701736
KLK5 kallikrein-related peptidase 5 0.00701074
FGB fibrinogen beta chain 0.00700132
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.00699204
LY6D lymphocyte antigen 6 complex, locus D 0.00698517
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 0.00694145
SCD5 stearoyl-CoA desaturase 5 0.00691977
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 0.00689266
BTG3 BTG family, member 3 0.00688441
OPHN1 oligophrenin 1 0.00687139
CD99 CD99 molecule 0.00685128
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.00684292
IFI44L interferon-induced protein 44-like 0.00683418
WFDC2 WAP four-disulfide core domain 2 0.00679788
KDM5D lysine (K)-specific demethylase 5D 0.00676932
DSP desmoplakin 0.00676621
MAGEA12 melanoma antigen family A12 0.00674302
DERA deoxyribose-phosphate aldolase (putative) 0.00669821
KRT16 keratin 16, type I 0.00669286
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.00666158
DCK deoxycytidine kinase 0.00664893
ETHE1 ethylmalonic encephalopathy 1 0.00663968
TRAM1 translocation associated membrane protein 1 0.00663414
GARS1 glycyl-tRNA synthetase 1 0.00660674
FGA fibrinogen alpha chain 0.0066064
ADA adenosine deaminase 0.00658997
H1-10 H1.10 linker histone 0.00656967
RAB25 RAB25, member RAS oncogene family 0.00656477
CLEC2B C-type lectin domain family 2, member B 0.00655469
OXA1L oxidase (cytochrome c) assembly 1-like 0.00651062
STC1 stanniocalcin 1 0.00650833
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 0.00650567
GSR glutathione reductase 0.00640599
TENT5A terminal nucleotidyltransferase 5A 0.00639908
PEG10 paternally expressed 10 0.00635699
TUBB2A tubulin, beta 2A class IIa 0.00635306
ELP1 elongator acetyltransferase complex subunit 1 0.00631349
ERAP2 endoplasmic reticulum aminopeptidase 2 0.00629371
MAL mal, T-cell differentiation protein 0.00628679
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 0.00628232
BTG1 B-cell translocation gene 1, anti-proliferative 0.00626245
TRAF3IP2 TRAF3 interacting protein 2 0.00622817
CPS1 carbamoyl-phosphate synthase 1, mitochondrial 0.00621758
EYA2 EYA transcriptional coactivator and phosphatase 2 0.00621345
SINHCAF SIN3-HDAC complex associated factor 0.00620872
ELANE elastase, neutrophil expressed 0.00620039
ITGA6 integrin, alpha 6 0.00619865
ANXA2P2 annexin A2 pseudogene 2 0.0061904
SPRR1A small proline-rich protein 1A 0.00616756
KRT14 keratin 14, type I 0.00614644
STK24 serine/threonine kinase 24 0.00612942
VSNL1 visinin-like 1 0.00609427
MAGEA1 melanoma antigen family A1 0.00608919
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide 0.00607493
EXOC5 exocyst complex component 5 0.00606566
ESRP1 epithelial splicing regulatory protein 1 0.0060538
EDN3 endothelin 3 0.00604765
DSG3 desmoglein 3 0.00601987
SPRR3 small proline-rich protein 3 0.00600489
MRPS30 mitochondrial ribosomal protein S30 0.0059778
CLDN7 claudin 7 0.00593931
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 0.00593488
MT1G metallothionein 1G 0.00591452
TMPRSS4 transmembrane protease, serine 4 0.00587098
RAB11FIP1 RAB11 family interacting protein 1 (class I) 0.00585831
YBX3 Y box binding protein 3 0.0058329
SLCO1B3 solute carrier organic anion transporter family, member 1B3 0.00579858
SRSF1 serine/arginine-rich splicing factor 1 0.00578913
DHRS7 dehydrogenase/reductase (SDR family) member 7 0.00578913
HIPK3 homeodomain interacting protein kinase 3 0.00578556
TFPI2 tissue factor pathway inhibitor 2 0.00578304
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide 0.00576081
HOXB7 homeobox B7 0.00575003
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein 0.00572336
RPS4Y1 ribosomal protein S4, Y-linked 1 0.0057037
NMU neuromedin U 0.00569732
FGG fibrinogen gamma chain 0.00568385
MBD2 methyl-CpG binding domain protein 2 0.00566638
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 0.00565091
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 0.00562664
ZNF207 zinc finger protein 207 0.00562456
PERP PERP, TP53 apoptosis effector 0.00562267
APOH apolipoprotein H (beta-2-glycoprotein I) 0.0056223
C4BPA complement component 4 binding protein, alpha 0.00560372
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.00559341
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.00556831
PI3 peptidase inhibitor 3, skin-derived 0.00554089
CFAP20 cilia and flagella associated protein 20 0.00549426
S100A7 S100 calcium binding protein A7 0.00548507
XPO7 exportin 7 0.00546245
DAD1 defender against cell death 1 0.00543994
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 0.00543778
FOXG1 forkhead box G1 0.00543565
KLK7 kallikrein-related peptidase 7 0.00541741
RPL35 ribosomal protein L35 0.0054035
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.00540261
FABP1 fatty acid binding protein 1, liver 0.00539125
SLC6A15 solute carrier family 6 (neutral amino acid transporter), member 15 0.00539044
CDC42SE1 CDC42 small effector 1 0.00538542
CFI complement factor I 0.00536798
ACTB actin, beta 0.00535566
MVP major vault protein 0.00535017
CAPRIN1 cell cycle associated protein 1 0.00533541
SPRR2B small proline-rich protein 2B 0.00531604
TYR tyrosinase 0.00530615
UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4 0.00530403
APOC3 apolipoprotein C-III 0.00530374
TCTN2 tectonic family member 2 0.00529973
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 0.00529672
COL4A6 collagen, type IV, alpha 6 0.00529449
MET MET proto-oncogene, receptor tyrosine kinase 0.00526315
RAB5C RAB5C, member RAS oncogene family 0.0052531
USP9Y ubiquitin specific peptidase 9, Y-linked 0.00524551
AK2 adenylate kinase 2 0.00524093
TGFBI transforming growth factor, beta-induced, 68kDa 0.00523313
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.0052237
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) 0.00521577
EIF5 eukaryotic translation initiation factor 5 0.0052151
MED6 mediator complex subunit 6 0.00521174
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.00521149
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.00520088
PON3 paraoxonase 3 0.00519962
TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa 0.00519553
PRTN3 proteinase 3 0.00517891
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 0.00516073
C3 complement component 3 0.00515001
STMN2 stathmin 2 0.00513771
EDNRB endothelin receptor type B 0.0051364
CXCL5 chemokine (C-X-C motif) ligand 5 0.00512993
KLF4 Kruppel-like factor 4 (gut) 0.00512468
CP ceruloplasmin (ferroxidase) 0.00511895
ADAMDEC1 ADAM-like, decysin 1 0.00511566
AHNAK AHNAK nucleoprotein 0.00511206
RPL29 ribosomal protein L29 0.00510193
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 0.0050998
MAP2K6 mitogen-activated protein kinase kinase 6 0.00508331
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 0.00508156
MCM2 minichromosome maintenance complex component 2 0.00507393
NMB neuromedin B 0.00506591
PITX1 paired-like homeodomain 1 0.0050637
EIF3F eukaryotic translation initiation factor 3, subunit F 0.0050606
HPRT1 hypoxanthine phosphoribosyltransferase 1 0.00505934
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 0.0050498
TMOD3 tropomodulin 3 (ubiquitous) 0.00504187
MED1 mediator complex subunit 1 0.00503992
RBBP4 retinoblastoma binding protein 4 0.00503908
SCARB2 scavenger receptor class B, member 2 0.00503065
PNN pinin, desmosome associated protein 0.00502475
H1-0 H1.0 linker histone 0.00501932
ATF4 activating transcription factor 4 0.00501331
TACSTD2 tumor-associated calcium signal transducer 2 0.0049892
PUM1 pumilio RNA-binding family member 1 0.00498026
EI24 etoposide induced 2.4 0.00497121
SAA4 serum amyloid A4, constitutive 0.00496751
ANG angiogenin, ribonuclease, RNase A family, 5 0.00495753
PHOX2B paired-like homeobox 2b 0.00495618
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme 0.00495193
MTUS1 microtubule associated tumor suppressor 1 0.00495074
ABHD17B abhydrolase domain containing 17B 0.00495055
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 0.00494821
CREG1 cellular repressor of E1A-stimulated genes 1 0.00494433
DSC2 desmocollin 2 0.0049279
TTC17 tetratricopeptide repeat domain 17 0.00492536
KPNA4 karyopherin alpha 4 (importin alpha 3) 0.0049204
SET SET nuclear proto-oncogene 0.00490892
LGALS13 lectin, galactoside-binding, soluble, 13 0.00490517
SCAMP1 secretory carrier membrane protein 1 0.00490415
CDC42 cell division cycle 42 0.00489935
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 0.00489296
REEP5 receptor accessory protein 5 0.00489075
CRP C-reactive protein, pentraxin-related 0.00488463
LGALS4 lectin, galactoside-binding, soluble, 4 0.00486553
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 0.00486153
GOLT1B golgi transport 1B 0.00484599
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 0.00483777
PUF60 poly-U binding splicing factor 60KDa 0.00482801
BEX1 brain expressed, X-linked 1 0.00481919
TMEM230 transmembrane protein 230 0.00481287
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 0.00478335
SST somatostatin 0.0047803
SOX4 SRY (sex determining region Y)-box 4 0.00477639
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 0.00477512
FZD6 frizzled class receptor 6 0.00477394
FCGBP Fc fragment of IgG binding protein 0.00477165
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta 0.00476449
WDR1 WD repeat domain 1 0.00475254
HLA-B major histocompatibility complex, class I, B 0.00474177
DLAT dihydrolipoamide S-acetyltransferase 0.00473115
PPP6C protein phosphatase 6, catalytic subunit 0.00473108
RSL1D1 ribosomal L1 domain containing 1 0.00473053
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 0.00472343
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 0.00471953
PMEL premelanosome protein 0.00471738
TYRP1 tyrosinase-related protein 1 0.00471737
SCEL sciellin 0.00471317
TCF4 transcription factor 4 0.0047128
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 0.00471263
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 0.00471192
KLF5 Kruppel-like factor 5 (intestinal) 0.00471139
MRPL18 mitochondrial ribosomal protein L18 0.00471088
RPL8 ribosomal protein L8 0.00470488
ODAM odontogenic, ameloblast asssociated 0.00469919
MPZL2 myelin protein zero-like 2 0.00468965

decreased expression

Symbol Name Standardized Value
TXNDC9 thioredoxin domain containing 9 -0.0161198
C3ORF14 chromosome 3 open reading frame 14 -0.0126569
AZGP1 alpha-2-glycoprotein 1, zinc-binding -0.0117693
AMIGO2 adhesion molecule with Ig-like domain 2 -0.0111704
IGFBP5 insulin-like growth factor binding protein 5 -0.010996
BGN biglycan -0.0107387
COMP cartilage oligomeric matrix protein -0.0105258
STK10 serine/threonine kinase 10 -0.0101987
KRT23 keratin 23, type I -0.0100112
CPA3 carboxypeptidase A3 (mast cell) -0.00997612
TARP TCR gamma alternate reading frame protein -0.00996116
MGP matrix Gla protein -0.0098515
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.00977164
SFRP4 secreted frizzled-related protein 4 -0.00967585
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C -0.00947881
PDLIM3 PDZ and LIM domain 3 -0.00947468
TRIB2 tribbles pseudokinase 2 -0.00941764
VCAM1 vascular cell adhesion molecule 1 -0.00933405
THBS4 thrombospondin 4 -0.00927718
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 -0.00909478
SCUBE2 signal peptide, CUB domain, EGF-like 2 -0.00904583
CCL5 chemokine (C-C motif) ligand 5 -0.00904535
NEFH neurofilament, heavy polypeptide -0.00891247
GSTM3 glutathione S-transferase mu 3 (brain) -0.00879188
RTN2 reticulon 2 -0.00857446
SULF1 sulfatase 1 -0.00837203
IGFBP4 insulin-like growth factor binding protein 4 -0.0083641
PLIN2 perilipin 2 -0.0083337
LPCAT1 lysophosphatidylcholine acyltransferase 1 -0.00824094
TBC1D31 TBC1 domain family, member 31 -0.00820601
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -0.00807434
RHOB ras homolog family member B -0.00807332
THY1 Thy-1 cell surface antigen -0.00804233
NBL1 neuroblastoma 1, DAN family BMP antagonist -0.00788789
FBLN1 fibulin 1 -0.00782712
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 -0.00777892
SORBS1 sorbin and SH3 domain containing 1 -0.00772866
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.00772539
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -0.00765426
NIBAN1 niban apoptosis regulator 1 -0.00765032
TSPYL5 TSPY-like 5 -0.00764449
G0S2 G0/G1 switch 2 -0.00755746
ELN elastin -0.00751024
MSMB microseminoprotein, beta- -0.00749936
PENK proenkephalin -0.00748831
DDAH1 dimethylarginine dimethylaminohydrolase 1 -0.00747599
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 -0.00747593
ABAT 4-aminobutyrate aminotransferase -0.00732584
PTGIS prostaglandin I2 (prostacyclin) synthase -0.00731752
PRKACB protein kinase, cAMP-dependent, catalytic, beta -0.00728352
LYZ lysozyme -0.00723706
NPAS2 neuronal PAS domain protein 2 -0.00718811
FBP1 fructose-1,6-bisphosphatase 1 -0.00716145
PCP4 Purkinje cell protein 4 -0.00706355
LIMCH1 LIM and calponin homology domains 1 -0.00705379
PDE10A phosphodiesterase 10A -0.00703175
PDE4A phosphodiesterase 4A, cAMP-specific -0.00699662
PHTF2 putative homeodomain transcription factor 2 -0.00695558
FXYD6 FXYD domain containing ion transport regulator 6 -0.00693674
OSBPL8 oxysterol binding protein-like 8 -0.00688767
ITGAV integrin, alpha V -0.00686101
ISYNA1 inositol-3-phosphate synthase 1 -0.00682357
COL11A1 collagen, type XI, alpha 1 -0.00680746
VEGFA vascular endothelial growth factor A -0.00679352
CLU clusterin -0.0067681
S100P S100 calcium binding protein P -0.00671412
NR2F2 nuclear receptor subfamily 2, group F, member 2 -0.00668465
BPHL biphenyl hydrolase-like (serine hydrolase) -0.00665686
IL7R interleukin 7 receptor -0.00664149
TAPBP TAP binding protein (tapasin) -0.0066328
MB myoglobin -0.00661975
ALOX15B arachidonate 15-lipoxygenase, type B -0.00661123
H2AFV H2A histone family, member V -0.00660006
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -0.00653044
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 -0.00649538
INHBA inhibin, beta A -0.00647878
TIMP1 TIMP metallopeptidase inhibitor 1 -0.00647526
DUSP3 dual specificity phosphatase 3 -0.0064382
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) -0.00643534
SUB1 SUB1 homolog (S. cerevisiae) -0.00638669
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like -0.00638509
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 -0.006385
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor -0.00636545
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) -0.00632366
AEBP1 AE binding protein 1 -0.00632325
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 -0.00631812
TNNT1 troponin T type 1 (skeletal, slow) -0.00626444
TAGLN transgelin -0.00624348
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 -0.00623879
SMC1A structural maintenance of chromosomes 1A -0.00623544
MICU2 mitochondrial calcium uptake 2 -0.00623217
CDK17 cyclin-dependent kinase 17 -0.00618101
ACP5 acid phosphatase 5, tartrate resistant -0.00617797
FASN fatty acid synthase -0.00617225
DHRS2 dehydrogenase/reductase (SDR family) member 2 -0.00617022
BRD4 bromodomain containing 4 -0.00611735
PTPRD protein tyrosine phosphatase, receptor type, D -0.00611324
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 -0.0061012
COL16A1 collagen, type XVI, alpha 1 -0.00608632
PLAAT3 phospholipase A and acyltransferase 3 -0.00605413
GMPR guanosine monophosphate reductase -0.00598375
SCRG1 stimulator of chondrogenesis 1 -0.00597329
THBS1 thrombospondin 1 -0.00596716
ANK2 ankyrin 2, neuronal -0.00591349
CCN2 cellular communication network factor 2 -0.00590991
CCNA2 cyclin A2 -0.00589599
SPARCL1 SPARC-like 1 (hevin) -0.00588509
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -0.00585405
PTK2 protein tyrosine kinase 2 -0.00585116
NQO2 NAD(P)H dehydrogenase, quinone 2 -0.00581276
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing -0.00580961
COL14A1 collagen, type XIV, alpha 1 -0.00579058
TYROBP TYRO protein tyrosine kinase binding protein -0.0057763
ANKRD36 ankyrin repeat domain 36 -0.00575122
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -0.00574622
NINJ2 ninjurin 2 -0.00573782
RRM2 ribonucleotide reductase M2 -0.00573554
PDZK1IP1 PDZK1 interacting protein 1 -0.005708
PDGFC platelet derived growth factor C -0.0057031
LUM lumican -0.00564536
ARMCX1 armadillo repeat containing, X-linked 1 -0.00564073
IQCE IQ motif containing E -0.00562902
TRIM8 tripartite motif containing 8 -0.00561247
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 -0.00559396
LIPT1 lipoyltransferase 1 -0.00559256
EFHD1 EF-hand domain family, member D1 -0.00557508
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 -0.00556768
PAK1IP1 PAK1 interacting protein 1 -0.0055675
DES desmin -0.00555715
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11 -0.00553897
TRPS1 trichorhinophalangeal syndrome I -0.00553102
DACT1 dishevelled-binding antagonist of beta-catenin 1 -0.0055252
CTSW cathepsin W -0.00551798
TMX4 thioredoxin-related transmembrane protein 4 -0.00551445
PDLIM5 PDZ and LIM domain 5 -0.00549373
NKG7 natural killer cell granule protein 7 -0.00549154
NR2F1 nuclear receptor subfamily 2, group F, member 1 -0.00548594
MTCL1 microtubule crosslinking factor 1 -0.00547896
GSTT2 glutathione S-transferase theta 2 (gene/pseudogene) -0.00547588
NDNF neuron-derived neurotrophic factor -0.00547071
ADAM9 ADAM metallopeptidase domain 9 -0.00546523
CAPG capping protein (actin filament), gelsolin-like -0.00546038
ALOX5 arachidonate 5-lipoxygenase -0.00544594
MINK1 misshapen-like kinase 1 -0.00544485
XIC X chromosome inactivation center -0.00544231
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) -0.00543095
FERMT2 fermitin family member 2 -0.00541985
RHOBTB1 Rho-related BTB domain containing 1 -0.00541456
TDP2 tyrosyl-DNA phosphodiesterase 2 -0.00539384
CRIP2 cysteine-rich protein 2 -0.0053841
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 -0.00538381
PDPK1 3-phosphoinositide dependent protein kinase 1 -0.00536997
WWC3 WWC family member 3 -0.00535368
NUAK1 NUAK family, SNF1-like kinase, 1 -0.00535343
SEPTIN10 septin 10 -0.00534547
ISLR immunoglobulin superfamily containing leucine-rich repeat -0.00534153
DMTF1 cyclin D binding myb-like transcription factor 1 -0.00528933
SRGN serglycin -0.00528628
NUSAP1 nucleolar and spindle associated protein 1 -0.00528216
DACH1 dachshund family transcription factor 1 -0.00527857
VDAC1 voltage-dependent anion channel 1 -0.00526386
PLN phospholamban -0.00525307
NPTX2 neuronal pentraxin II -0.00525209
TEX30 testis expressed 30 -0.00523175
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) -0.00523131
TMEM131 transmembrane protein 131 -0.00519194
SOX9 SRY (sex determining region Y)-box 9 -0.00517887
MYBPC1 myosin binding protein C, slow type -0.00517654
DLK1 delta-like 1 homolog (Drosophila) -0.005176
ANXA6 annexin A6 -0.00516761
RAB20 RAB20, member RAS oncogene family -0.00516396
CD300A CD300a molecule -0.00514964
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b -0.00513661
NXN nucleoredoxin -0.00509492
NAMPT nicotinamide phosphoribosyltransferase -0.00509239
TTC39A tetratricopeptide repeat domain 39A -0.00508492
EDNRA endothelin receptor type A -0.00508039
TSPAN5 tetraspanin 5 -0.00507906
NCAM1 neural cell adhesion molecule 1 -0.00506187
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 -0.00505099
QKI QKI, KH domain containing, RNA binding -0.00504338
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 -0.0050414
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha -0.00503878
ARHGAP29 Rho GTPase activating protein 29 -0.0050304
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein -0.00501458
ZBTB18 zinc finger and BTB domain containing 18 -0.00500809
AQP1 aquaporin 1 (Colton blood group) -0.00500034
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) -0.00499892
POMZP3 POM121 and ZP3 fusion -0.004986
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) -0.00497254
TBL1X transducin (beta)-like 1X-linked -0.0049684
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 -0.00496334
IFNAR1 interferon (alpha, beta and omega) receptor 1 -0.00496263
ADCY9 adenylate cyclase 9 -0.00495909
PIP prolactin-induced protein -0.00494951
METTL7A methyltransferase like 7A -0.00494901
CYTIP cytohesin 1 interacting protein -0.00493855
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -0.00493396
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2 -0.0049313
BCAT2 branched chain amino-acid transaminase 2, mitochondrial -0.00492791
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) -0.00492531
ZCCHC24 zinc finger, CCHC domain containing 24 -0.00491832
LXN latexin -0.00491433
CUX2 cut-like homeobox 2 -0.0049138
SLC38A1 solute carrier family 38, member 1 -0.00490694
WT1 Wilms tumor 1 -0.00489211
PTP4A3 protein tyrosine phosphatase type IVA, member 3 -0.00488423
ALDH4A1 aldehyde dehydrogenase 4 family, member A1 -0.0048814
GCC2 GRIP and coiled-coil domain containing 2 -0.00487141
ZFPM2 zinc finger protein, FOG family member 2 -0.00485371
CPVL carboxypeptidase, vitellogenic-like -0.00484709
MGLL monoglyceride lipase -0.00484648
IL10RA interleukin 10 receptor, alpha -0.00484635
SH3BGRL SH3 domain binding glutamate-rich protein like -0.00484508
RXRA retinoid X receptor, alpha -0.00484355
VWF von Willebrand factor -0.00483924
TCEAL2 transcription elongation factor A (SII)-like 2 -0.00483745
TST thiosulfate sulfurtransferase (rhodanese) -0.00483169
SDC1 syndecan 1 -0.0048161
MYL1 myosin, light chain 1, alkali; skeletal, fast -0.00481314
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 -0.00480972
WASF1 WAS protein family, member 1 -0.00480549
CTSK cathepsin K -0.0048003
HOXC10 homeobox C10 -0.00479486
CRY1 cryptochrome circadian clock 1 -0.0047904
WASHC4 WASH complex subunit 4 -0.0047862
PKP4 plakophilin 4 -0.00477712
SOBP sine oculis binding protein homolog (Drosophila) -0.00477688
SPART spartin -0.00477327
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) -0.00477195
FHL1 four and a half LIM domains 1 -0.00476915
FKBP4 FK506 binding protein 4, 59kDa -0.00475409
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.00474122
HMGB3 high mobility group box 3 -0.00473671
SYNM synemin, intermediate filament protein -0.00472953
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) -0.00471859
TRAF5 TNF receptor-associated factor 5 -0.00471383
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G -0.00470825
FBN2 fibrillin 2 -0.0047056
EFR3A EFR3 homolog A (S. cerevisiae) -0.00470014
HSPB8 heat shock 22kDa protein 8 -0.00469768
PDGFRL platelet-derived growth factor receptor-like -0.00469008
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -0.00468012
LMO3 LIM domain only 3 (rhombotin-like 2) -0.0046782
PGAM1 phosphoglycerate mutase 1 (brain) -0.00466975
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) -0.00466415
RPRD2 regulation of nuclear pre-mRNA domain containing 2 -0.00465544
NFASC neurofascin -0.00465126
ACSL1 acyl-CoA synthetase long-chain family member 1 -0.00464157
SCAMP4 secretory carrier membrane protein 4 -0.00463835