NEUROD2 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description neuronal differentiation 2|This gene encodes a member of the neuroD family of neurogenic basic helix-loop-helix (bHLH) proteins. Expression of this gene can induce transcription from neuron-specific promoters, such as the GAP-43 promoter, which contain a specific DNA sequence known as an E-box. The product of the human gene can induce neurogenic differentiation in non-neuronal cells in Xenopus embryos, and is thought to play a role in the determination and maintenance of neuronal cell fates. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 4761)
External Link https://ncbi.nlm.nih.gov/gene/4761
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Genes

498 genes differentially expressed following the NEUROD2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
LCN2 lipocalin 2 0.0188744
S100A8 S100 calcium binding protein A8 0.0180988
LGALS13 lectin, galactoside-binding, soluble, 13 0.0180279
S100A9 S100 calcium binding protein A9 0.0179046
HBB hemoglobin, beta 0.0163603
MAL mal, T-cell differentiation protein 0.0159783
MNDA myeloid cell nuclear differentiation antigen 0.0152933
BMP4 bone morphogenetic protein 4 0.0152578
FCN1 ficolin (collagen/fibrinogen domain containing) 1 0.0148421
SSBP2 single-stranded DNA binding protein 2 0.0147486
NTS neurotensin 0.0145531
PLBD1 phospholipase B domain containing 1 0.0140345
CLC Charcot-Leyden crystal galectin 0.0136451
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.0133126
SELL selectin L 0.0131962
S100A12 S100 calcium binding protein A12 0.012872
CETN2 centrin, EF-hand protein, 2 0.012796
CD48 CD48 molecule 0.0124228
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.0121278
SYNGR3 synaptogyrin 3 0.0121034
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 0.0119844
CSTA cystatin A (stefin A) 0.0119524
GCA grancalcin, EF-hand calcium binding protein 0.0117095
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.0117088
CYBB cytochrome b-245, beta polypeptide 0.0117041
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 0.011697
RNASE6 ribonuclease, RNase A family, k6 0.0115915
CCNA2 cyclin A2 0.0115378
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 0.0115063
NELL2 NEL-like 2 (chicken) 0.0113867
MDFIC MyoD family inhibitor domain containing 0.0113809
CES1 carboxylesterase 1 0.0113057
CD300A CD300a molecule 0.0112302
C5AR1 complement component 5a receptor 1 0.0111972
ANXA3 annexin A3 0.0109877
MAP2K6 mitogen-activated protein kinase kinase 6 0.010972
GPR183 G protein-coupled receptor 183 0.0109636
LTA4H leukotriene A4 hydrolase 0.0109041
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide 0.0108987
PBX1 pre-B-cell leukemia homeobox 1 0.0108857
RPS4Y1 ribosomal protein S4, Y-linked 1 0.0108262
CTSS cathepsin S 0.0107898
ARID4A AT rich interactive domain 4A (RBP1-like) 0.0107577
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.0106985
TREM1 triggering receptor expressed on myeloid cells 1 0.0104628
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.0104201
ANXA1 annexin A1 0.0102953
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.0102772
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 0.0102335
STEAP1 six transmembrane epithelial antigen of the prostate 1 0.0102072
ANXA6 annexin A6 0.010139
BHLHE41 basic helix-loop-helix family, member e41 0.0101366
SAMHD1 SAM domain and HD domain 1 0.0100853
NEBL nebulette 0.00998521
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 0.00998203
NME4 NME/NM23 nucleoside diphosphate kinase 4 0.00993041
FPR1 formyl peptide receptor 1 0.00989543
ERAP2 endoplasmic reticulum aminopeptidase 2 0.00981426
NCF2 neutrophil cytosolic factor 2 0.00979829
FGR FGR proto-oncogene, Src family tyrosine kinase 0.0097131
MPO myeloperoxidase 0.00969604
PGD phosphogluconate dehydrogenase 0.00961746
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) 0.00961251
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 0.00950438
PUF60 poly-U binding splicing factor 60KDa 0.00949623
MMP12 matrix metallopeptidase 12 0.0094854
OLFM4 olfactomedin 4 0.00947275
AQP9 aquaporin 9 0.009445
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.00939284
KRCC1 lysine-rich coiled-coil 1 0.00933644
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 0.0092963
DUOX2 dual oxidase 2 0.00926321
AUTS2 autism susceptibility candidate 2 0.00924677
COMMD10 COMM domain containing 10 0.00923262
FGL2 fibrinogen-like 2 0.00920102
NQO1 NAD(P)H dehydrogenase, quinone 1 0.00917943
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) 0.00914149
ADD3 adducin 3 (gamma) 0.00900013
MAGT1 magnesium transporter 1 0.00889828
LXN latexin 0.00889587
TYROBP TYRO protein tyrosine kinase binding protein 0.0088922
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 0.00884814
KLK8 kallikrein-related peptidase 8 0.00871458
BIRC5 baculoviral IAP repeat containing 5 0.00863815
AURKB aurora kinase B 0.00863697
TADA2A transcriptional adaptor 2A 0.00862003
AZIN1 antizyme inhibitor 1 0.00861853
CXCL8 chemokine (C-X-C motif) ligand 8 0.00860173
CFD complement factor D (adipsin) 0.00857145
GPR65 G protein-coupled receptor 65 0.00855529
BMP7 bone morphogenetic protein 7 0.00853895
PADI2 peptidyl arginine deiminase, type II 0.00852222
THYN1 thymocyte nuclear protein 1 0.00848329
CLEC7A C-type lectin domain family 7, member A 0.00847652
ALCAM activated leukocyte cell adhesion molecule 0.00847049
NMB neuromedin B 0.00843604
CPVL carboxypeptidase, vitellogenic-like 0.00843372
HILPDA hypoxia inducible lipid droplet-associated 0.00841632
WFDC2 WAP four-disulfide core domain 2 0.00834051
ARRB2 arrestin, beta 2 0.00833563
DHFR dihydrofolate reductase 0.00832273
CDH3 cadherin 3, type 1, P-cadherin (placental) 0.00830063
CCNA1 cyclin A1 0.00828724
RAB11FIP1 RAB11 family interacting protein 1 (class I) 0.0082808
CD86 CD86 molecule 0.00827426
KRT13 keratin 13, type I 0.00826317
CLEC4A C-type lectin domain family 4, member A 0.00825982
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 0.00825106
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 0.00821522
GLIPR1 GLI pathogenesis-related 1 0.00820062
HPF1 histone PARylation factor 1 0.00819584
ARHGAP15 Rho GTPase activating protein 15 0.00816976
SIDT1 SID1 transmembrane family, member 1 0.00809038
RNASE3 ribonuclease, RNase A family, 3 0.00808718
KLK6 kallikrein-related peptidase 6 0.00807582
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 0.00805806
FCGBP Fc fragment of IgG binding protein 0.00803504
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 0.00802168
DDR2 discoidin domain receptor tyrosine kinase 2 0.007995
AMD1 adenosylmethionine decarboxylase 1 0.00799339
PAN2 PAN2 poly(A) specific ribonuclease subunit 0.00799018
PI3 peptidase inhibitor 3, skin-derived 0.00795136
CCR1 chemokine (C-C motif) receptor 1 0.00794429
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 0.0079094
DDHD2 DDHD domain containing 2 0.00788041
IL2RG interleukin 2 receptor, gamma 0.00787467
CDCA4 cell division cycle associated 4 0.00786912
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.00786518
PTBP3 polypyrimidine tract binding protein 3 0.00785903
FABP7 fatty acid binding protein 7, brain 0.00784555
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00783393
CLEC5A C-type lectin domain family 5, member A 0.00782583
MAGEH1 melanoma antigen family H1 0.00781283
RHOT1 ras homolog family member T1 0.00779809
AGTPBP1 ATP/GTP binding protein 1 0.0077828
DPYD dihydropyrimidine dehydrogenase 0.00776916
FAM171A1 family with sequence similarity 171, member A1 0.00776081
RNASEH2A ribonuclease H2, subunit A 0.00775589
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 0.00775184
GIMAP4 GTPase, IMAP family member 4 0.00775122
CANX calnexin 0.00772629
PRIM1 primase, DNA, polypeptide 1 (49kDa) 0.00772359
SEPHS1 selenophosphate synthetase 1 0.00770583
SPRR3 small proline-rich protein 3 0.00768434
SRPX2 sushi-repeat containing protein, X-linked 2 0.00767442
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 0.0076679
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.00766491
NCAM1 neural cell adhesion molecule 1 0.00764006
NMU neuromedin U 0.00762626
LRRN3 leucine rich repeat neuronal 3 0.00761409
ARL3 ADP-ribosylation factor-like 3 0.00759392
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 0.00759275
ENO2 enolase 2 (gamma, neuronal) 0.00758523
KCTD12 potassium channel tetramerization domain containing 12 0.00756338
ZNF204P zinc finger protein 204, pseudogene 0.00753879
HCRT hypocretin (orexin) neuropeptide precursor 0.00751897
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.00751419
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 0.00749978
RNF130 ring finger protein 130 0.00749836
S100A7 S100 calcium binding protein A7 0.00749052
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 0.00747919
IFT52 intraflagellar transport 52 0.00747336
HSDL2 hydroxysteroid dehydrogenase like 2 0.00744376
MUC5AC mucin 5AC, oligomeric mucus/gel-forming 0.00743526
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.00743055
PILRA paired immunoglobin-like type 2 receptor alpha 0.00738569
LY86 lymphocyte antigen 86 0.00736147
S100B S100 calcium binding protein B 0.00733773
MLF1 myeloid leukemia factor 1 0.00732718
TCEAL1 transcription elongation factor A (SII)-like 1 0.0072914
NRN1 neuritin 1 0.00728119
TMEM14B transmembrane protein 14B 0.00727988
RAB27A RAB27A, member RAS oncogene family 0.00726223
TSPAN6 tetraspanin 6 0.00724429
PF4 platelet factor 4 0.0072299
SYK spleen tyrosine kinase 0.00722751
TLR1 toll-like receptor 1 0.00722406
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 0.00722079
DHRS9 dehydrogenase/reductase (SDR family) member 9 0.00721212
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 0.00721059
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 0.00718977
FLOT2 flotillin 2 0.00718248
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.00718109
AIF1 allograft inflammatory factor 1 0.00717992
CCR2 chemokine (C-C motif) receptor 2 0.00717604
LYZ lysozyme 0.0071725
CXCR4 chemokine (C-X-C motif) receptor 4 0.00715488
SPC25 SPC25, NDC80 kinetochore complex component 0.00714954
ADRA2A adrenoceptor alpha 2A 0.00711145
TM6SF1 transmembrane 6 superfamily member 1 0.00709959
MYO5C myosin VC 0.00708
CAND1 cullin-associated and neddylation-dissociated 1 0.00707147
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 0.00707093
ATP10B ATPase, class V, type 10B 0.0070576
IQGAP2 IQ motif containing GTPase activating protein 2 0.00705008
LY75 lymphocyte antigen 75 0.00703637
LGALS1 lectin, galactoside-binding, soluble, 1 0.00702609
COPS4 COP9 signalosome subunit 4 0.00700863
CAPG capping protein (actin filament), gelsolin-like 0.00698931
B3GNT1 0.00697543
RNF144A ring finger protein 144A 0.00697007
HMBS hydroxymethylbilane synthase 0.00696913
TACSTD2 tumor-associated calcium signal transducer 2 0.00694937
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.00694458
TSPAN31 tetraspanin 31 0.00693991
TFDP1 transcription factor Dp-1 0.00690941
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 0.00690717
BCL2A1 BCL2-related protein A1 0.00689718
NAMPT nicotinamide phosphoribosyltransferase 0.00686796
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase 0.00684901
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 0.00684812
NT5DC2 5'-nucleotidase domain containing 2 0.00683242
PSIP1 PC4 and SFRS1 interacting protein 1 0.00682353
GPM6A glycoprotein M6A 0.00682309
TMPRSS4 transmembrane protease, serine 4 0.00681902
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.00681341
ACP6 acid phosphatase 6, lysophosphatidic 0.00680664
MUC16 mucin 16, cell surface associated 0.00680215
PSRC1 proline/serine-rich coiled-coil 1 0.00679702
MUC4 mucin 4, cell surface associated 0.00678001
LEPR leptin receptor 0.00676862
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.00676803
TRIM16 tripartite motif containing 16 0.00676638
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.00676499
SALL2 spalt-like transcription factor 2 0.00675832
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.00674807
NCAPD3 non-SMC condensin II complex, subunit D3 0.00672626
TMOD1 tropomodulin 1 0.00672456
NIPSNAP2 nipsnap homolog 2 0.0067238
LST1 leukocyte specific transcript 1 0.0067207
DEFB1 defensin, beta 1 0.0067179
ZNF652 zinc finger protein 652 0.00669801
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 0.00669643
SLC2A4RG SLC2A4 regulator 0.00669466
C3ORF14 chromosome 3 open reading frame 14 0.0066931
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.00669044
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 0.0066876
ASF1B anti-silencing function 1B histone chaperone 0.0066835
AK4 adenylate kinase 4 0.00668009
LMNB1 lamin B1 0.00666821
LARS1 leucyl-tRNA synthetase 1 0.00666069
BUB1 BUB1 mitotic checkpoint serine/threonine kinase 0.00665381
TPM4 tropomyosin 4 0.00665365
WWOX WW domain containing oxidoreductase 0.0066486
MMD monocyte to macrophage differentiation-associated 0.00663964
EYA2 EYA transcriptional coactivator and phosphatase 2 0.00663213
LAPTM5 lysosomal protein transmembrane 5 0.00662259
GINS2 GINS complex subunit 2 (Psf2 homolog) 0.00661999
PCP4 Purkinje cell protein 4 0.00661712
TMEM231 transmembrane protein 231 0.00661605

decreased expression

Symbol Name Standardized Value
KRT14 keratin 14, type I -0.0204019
CXCL14 chemokine (C-X-C motif) ligand 14 -0.0176882
SPRED2 sprouty-related, EVH1 domain containing 2 -0.0174698
CDC20 cell division cycle 20 -0.0166355
KRT17 keratin 17, type I -0.0163408
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.0160531
HSPA1A heat shock 70kDa protein 1A -0.0156649
SLC38A1 solute carrier family 38, member 1 -0.0150045
IFI27 interferon, alpha-inducible protein 27 -0.0145295
NNMT nicotinamide N-methyltransferase -0.0135312
ASS1 argininosuccinate synthase 1 -0.013492
SCGB1D2 secretoglobin, family 1D, member 2 -0.013434
PERP PERP, TP53 apoptosis effector -0.0133329
APOD apolipoprotein D -0.0131785
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -0.0131736
MT1E metallothionein 1E -0.013111
MAP7 microtubule-associated protein 7 -0.013024
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 -0.0128683
OSBPL10 oxysterol binding protein-like 10 -0.0127294
CCL19 chemokine (C-C motif) ligand 19 -0.0125795
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) -0.0124132
DYNLL1 dynein, light chain, LC8-type 1 -0.0122343
RFTN1 raftlin, lipid raft linker 1 -0.0122049
CXCL13 chemokine (C-X-C motif) ligand 13 -0.0118511
SNAI2 snail family zinc finger 2 -0.0117525
CXCL9 chemokine (C-X-C motif) ligand 9 -0.0116984
SLC39A14 solute carrier family 39 (zinc transporter), member 14 -0.0116039
DSP desmoplakin -0.0115533
LUM lumican -0.0114472
ECM1 extracellular matrix protein 1 -0.0114445
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 -0.0112095
HMOX1 heme oxygenase 1 -0.0111572
TES testin LIM domain protein -0.0111069
SCGB2A2 secretoglobin, family 2A, member 2 -0.011106
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 -0.0110806
DUSP5 dual specificity phosphatase 5 -0.0109995
ISG15 ISG15 ubiquitin-like modifier -0.0109148
ADIRF adipogenesis regulatory factor -0.010885
RTN2 reticulon 2 -0.0108659
RGS16 regulator of G-protein signaling 16 -0.0108635
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.0107185
MT1G metallothionein 1G -0.0106922
SCUBE2 signal peptide, CUB domain, EGF-like 2 -0.0106395
TFPI2 tissue factor pathway inhibitor 2 -0.01046
HIST1H2BK histone cluster 1, H2bk -0.0103621
TIMP1 TIMP metallopeptidase inhibitor 1 -0.0101744
CCN3 cellular communication network factor 3 -0.0101527
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 -0.0100813
GPNMB glycoprotein (transmembrane) nmb -0.0100668
CRYAB crystallin, alpha B -0.0099814
AQP3 aquaporin 3 (Gill blood group) -0.00996019
AMDHD2 amidohydrolase domain containing 2 -0.00973142
MVP major vault protein -0.00965116
OXA1L oxidase (cytochrome c) assembly 1-like -0.00962046
GADD45A growth arrest and DNA-damage-inducible, alpha -0.0096143
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A -0.0095327
TIMP3 TIMP metallopeptidase inhibitor 3 -0.00951796
RGS13 regulator of G-protein signaling 13 -0.00947025
MET MET proto-oncogene, receptor tyrosine kinase -0.00945335
COL6A2 collagen, type VI, alpha 2 -0.00940898
MAGEA3 melanoma antigen family A3 -0.00940811
CTSA cathepsin A -0.009382
MAOB monoamine oxidase B -0.00937678
ODC1 ornithine decarboxylase 1 -0.00937417
RND3 Rho family GTPase 3 -0.00935861
HOXC10 homeobox C10 -0.00934805
NUPR1 nuclear protein, transcriptional regulator, 1 -0.00930563
FHL2 four and a half LIM domains 2 -0.00930258
COMP cartilage oligomeric matrix protein -0.00929872
RRAGC Ras-related GTP binding C -0.00929626
MMP1 matrix metallopeptidase 1 -0.00929424
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.00929217
MT1M metallothionein 1M -0.00910967
VEGFA vascular endothelial growth factor A -0.00908272
MIR22HG MIR22 host gene -0.00903002
SIK1 salt-inducible kinase 1 -0.00900594
IGF1R insulin-like growth factor 1 receptor -0.00889732
KRT16 keratin 16, type I -0.00889475
SGK1 serum/glucocorticoid regulated kinase 1 -0.00887102
MT1X metallothionein 1X -0.00885471
PHLDA2 pleckstrin homology-like domain, family A, member 2 -0.00884003
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 -0.00877612
DDAH1 dimethylarginine dimethylaminohydrolase 1 -0.00877192
CXCL10 chemokine (C-X-C motif) ligand 10 -0.00875472
FKBP11 FK506 binding protein 11, 19 kDa -0.00874035
DIPK1A divergent protein kinase domain 1A -0.00869004
PMP22 peripheral myelin protein 22 -0.0086183
SCRG1 stimulator of chondrogenesis 1 -0.00861268
PLXND1 plexin D1 -0.00856445
ISG20 interferon stimulated exonuclease gene 20kDa -0.00849474
GOT1 glutamic-oxaloacetic transaminase 1, soluble -0.00848321
EIF5B eukaryotic translation initiation factor 5B -0.00848318
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 -0.00847806
PXDC1 PX domain containing 1 -0.00844574
ITPRID2 ITPR interacting domain containing 2 -0.0083982
CAPN2 calpain 2, (m/II) large subunit -0.00839402
MTCL1 microtubule crosslinking factor 1 -0.00835998
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) -0.00833476
PARP12 poly (ADP-ribose) polymerase family, member 12 -0.00832635
VCAM1 vascular cell adhesion molecule 1 -0.00828906
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 -0.00828785
RABGGTB Rab geranylgeranyltransferase, beta subunit -0.00825136
TXLNA taxilin alpha -0.00824963
ADCY9 adenylate cyclase 9 -0.0082418
SLC30A1 solute carrier family 30 (zinc transporter), member 1 -0.00810796
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 -0.00810546
KRT5 keratin 5, type II -0.00808635
OSR2 odd-skipped related transciption factor 2 -0.00806872
C1S complement component 1, s subcomponent -0.00805085
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -0.00801105
TMEM176B transmembrane protein 176B -0.0080096
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -0.00794765
MX1 MX dynamin-like GTPase 1 -0.00794265
TENT4A terminal nucleotidyltransferase 4A -0.00793544
IL32 interleukin 32 -0.00792654
CCL21 chemokine (C-C motif) ligand 21 -0.00792279
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -0.00787582
ZDHHC6 zinc finger, DHHC-type containing 6 -0.00781421
CEL carboxyl ester lipase -0.0078118
NFE2L1 nuclear factor, erythroid 2-like 1 -0.00779376
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 -0.00778534
STK26 serine/threonine protein kinase 26 -0.00778496
COL11A1 collagen, type XI, alpha 1 -0.00776688
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 -0.00774168
LOXL1 lysyl oxidase-like 1 -0.00772322
TGFBR3 transforming growth factor, beta receptor III -0.00772119
CP ceruloplasmin (ferroxidase) -0.00771935
MMP11 matrix metallopeptidase 11 -0.00771123
NOP2 NOP2 nucleolar protein -0.00770924
PPP1R3C protein phosphatase 1, regulatory subunit 3C -0.00769261
INHBA inhibin, beta A -0.0076809
SCGB2A1 secretoglobin, family 2A, member 1 -0.00767626
KRAS Kirsten rat sarcoma viral oncogene homolog -0.00767501
RABEP2 rabaptin, RAB GTPase binding effector protein 2 -0.00765471
MRPS30 mitochondrial ribosomal protein S30 -0.00763209
MFAP5 microfibrillar associated protein 5 -0.00761579
C11ORF24 chromosome 11 open reading frame 24 -0.0075828
PKP1 plakophilin 1 -0.00757044
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) -0.00756542
RBPMS RNA binding protein with multiple splicing -0.0075575
IGF2R insulin-like growth factor 2 receptor -0.00754668
SFN stratifin -0.00754607
PRSS23 protease, serine, 23 -0.00753759
IFI6 interferon, alpha-inducible protein 6 -0.00752006
TSPAN4 tetraspanin 4 -0.00746325
SWAP70 SWAP switching B-cell complex 70kDa subunit -0.00744396
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -0.0074222
DRAM1 DNA-damage regulated autophagy modulator 1 -0.00741338
DUSP7 dual specificity phosphatase 7 -0.00740948
GLS glutaminase -0.00739272
ENPEP glutamyl aminopeptidase (aminopeptidase A) -0.0073534
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -0.00735219
WASL Wiskott-Aldrich syndrome-like -0.00734209
MT1F metallothionein 1F -0.0073358
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 -0.00732884
IRF7 interferon regulatory factor 7 -0.00731823
IGFBP6 insulin-like growth factor binding protein 6 -0.00730807
LIMS1 LIM and senescent cell antigen-like domains 1 -0.00730259
SUGCT succinyl-CoA:glutarate-CoA transferase -0.00728568
CAV1 caveolin 1, caveolae protein, 22kDa -0.00727649
COL2A1 collagen, type II, alpha 1 -0.0072549
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -0.00724142
PRRC2C proline-rich coiled-coil 2C -0.00722849
CCN2 cellular communication network factor 2 -0.00722465
SLC16A6 solute carrier family 16, member 6 -0.00722461
CCNG2 cyclin G2 -0.00720875
FADS3 fatty acid desaturase 3 -0.00720617
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 -0.00719861
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 -0.00719084
EXT1 exostosin glycosyltransferase 1 -0.00714744
MYC v-myc avian myelocytomatosis viral oncogene homolog -0.00714594
LY6E lymphocyte antigen 6 complex, locus E -0.00712708
PROCR protein C receptor, endothelial -0.00712409
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.00712398
SLC39A6 solute carrier family 39 (zinc transporter), member 6 -0.00712107
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 -0.00709774
MT1H metallothionein 1H -0.00708978
TPP1 tripeptidyl peptidase I -0.0070753
MT1HL1 metallothionein 1H-like 1 -0.00706507
PKD1P1 polycystic kidney disease 1 (autosomal dominant) pseudogene 1 -0.00706332
LAMC2 laminin, gamma 2 -0.00704114
DUSP6 dual specificity phosphatase 6 -0.00703847
TNNI2 troponin I type 2 (skeletal, fast) -0.00703557
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 -0.00701613
LAMB1 laminin, beta 1 -0.00698135
POSTN periostin, osteoblast specific factor -0.00697606
ARHGAP29 Rho GTPase activating protein 29 -0.00696272
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 -0.00696266
AIM2 absent in melanoma 2 -0.00696
COL3A1 collagen, type III, alpha 1 -0.00695117
SOWAHC sosondowah ankyrin repeat domain family member C -0.00694182
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 -0.00693739
PDLIM4 PDZ and LIM domain 4 -0.00690484
TENT5A terminal nucleotidyltransferase 5A -0.00689598
TM4SF1 transmembrane 4 L six family member 1 -0.00688244
AMIGO2 adhesion molecule with Ig-like domain 2 -0.00687542
VGLL4 vestigial-like family member 4 -0.00687252
DKFZP586I1420 uncharacterized protein DKFZp586I1420 -0.00686923
PLAAT3 phospholipase A and acyltransferase 3 -0.00683173
SASH1 SAM and SH3 domain containing 1 -0.00682003
FNDC3B fibronectin type III domain containing 3B -0.00681652
STAT1 signal transducer and activator of transcription 1, 91kDa -0.00679951
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -0.00678226
MEST mesoderm specific transcript -0.00677235
NOTCH2NL notch 2 N-terminal like -0.00674239
C1QB complement component 1, q subcomponent, B chain -0.00673244
COL15A1 collagen, type XV, alpha 1 -0.00673186
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 -0.00673092
AKAP8L A kinase (PRKA) anchor protein 8-like -0.00672311
PLXNA2 plexin A2 -0.00671606
CFB complement factor B -0.00671216
NT5E 5'-nucleotidase, ecto (CD73) -0.0067007
ITSN2 intersectin 2 -0.00670055
STC2 stanniocalcin 2 -0.00668235
ASPN asporin -0.00668027
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 -0.00667183
MAMLD1 mastermind-like domain containing 1 -0.0066679
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 -0.00666309
CXCL11 chemokine (C-X-C motif) ligand 11 -0.0066367
HSPB8 heat shock 22kDa protein 8 -0.00663154
FN1 fibronectin 1 -0.00663105
NPY neuropeptide Y -0.00662259
CTSL cathepsin L -0.0066128
GAREM1 GRB2 associated regulator of MAPK1 subtype 1 -0.00660869
AMOTL2 angiomotin like 2 -0.00659005
SPRY4 sprouty homolog 4 (Drosophila) -0.00657437
MCL1 myeloid cell leukemia 1 -0.00656837
RETREG2 reticulophagy regulator family member 2 -0.00654296
KLHL41 kelch-like family member 41 -0.0065396
PPP1R15A protein phosphatase 1, regulatory subunit 15A -0.00650921
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 -0.00650745
TRIB1 tribbles pseudokinase 1 -0.00650501
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 -0.0064928
RAB8A RAB8A, member RAS oncogene family -0.006491
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) -0.00649009
PRKCZ protein kinase C, zeta -0.00647843
IER5 immediate early response 5 -0.00647563
JAG1 jagged 1 -0.00642083
PLXNB2 plexin B2 -0.00641771
MN1 meningioma (disrupted in balanced translocation) 1 -0.00641751
CGA glycoprotein hormones, alpha polypeptide -0.00640473
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 -0.00640142
CKM creatine kinase, muscle -0.00638944
CHIC2 cysteine-rich hydrophobic domain 2 -0.00638897
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 -0.00637506
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 -0.00637401
CD72 CD72 molecule -0.00637282
AKR1C1 aldo-keto reductase family 1, member C1 -0.00635948