| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | neurofibromin 1|This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 4763) |
| External Link | https://ncbi.nlm.nih.gov/gene/4763 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the NF1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MAP7 | microtubule-associated protein 7 | 0.0227068 |
| XIC | X chromosome inactivation center | 0.0166462 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0158069 |
| TPM4 | tropomyosin 4 | 0.0156072 |
| CA2 | carbonic anhydrase II | 0.0155541 |
| ANXA1 | annexin A1 | 0.015008 |
| CLU | clusterin | 0.0148351 |
| TRAM1 | translocation associated membrane protein 1 | 0.0145535 |
| TPD52L1 | tumor protein D52-like 1 | 0.0142075 |
| CSTA | cystatin A (stefin A) | 0.0141952 |
| CAV2 | caveolin 2 | 0.0141799 |
| CLEC2B | C-type lectin domain family 2, member B | 0.0141602 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.014089 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | 0.0137572 |
| ABLIM1 | actin binding LIM protein 1 | 0.0135783 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.0134785 |
| KRT23 | keratin 23, type I | 0.0129629 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0129116 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0128104 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.0127332 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | 0.0127216 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0126238 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 0.0125777 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.0125676 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | 0.0125188 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0124516 |
| IL6ST | interleukin 6 signal transducer | 0.012415 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | 0.0121974 |
| SPRR3 | small proline-rich protein 3 | 0.0121811 |
| CRYAB | crystallin, alpha B | 0.0120906 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0120892 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0119869 |
| PRNP | prion protein | 0.0119548 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.0119324 |
| RDX | radixin | 0.0118543 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | 0.0118479 |
| TLR4 | toll-like receptor 4 | 0.0117847 |
| PROS1 | protein S (alpha) | 0.0117693 |
| ADIRF | adipogenesis regulatory factor | 0.0117328 |
| CRABP2 | cellular retinoic acid binding protein 2 | 0.0117133 |
| SELENOT | selenoprotein T | 0.0116515 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | 0.0114376 |
| LY96 | lymphocyte antigen 96 | 0.0112852 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0112729 |
| KLK7 | kallikrein-related peptidase 7 | 0.0112638 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 0.0112532 |
| KLK10 | kallikrein-related peptidase 10 | 0.0111912 |
| KLK6 | kallikrein-related peptidase 6 | 0.0111542 |
| PTK2 | protein tyrosine kinase 2 | 0.0111356 |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 | 0.0111224 |
| S100P | S100 calcium binding protein P | 0.0110449 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | 0.0109577 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | 0.0109116 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.0108397 |
| S100A9 | S100 calcium binding protein A9 | 0.0108336 |
| CTTN | cortactin | 0.0107288 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0106005 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.0105751 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 | 0.0105648 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | 0.0105052 |
| ANXA3 | annexin A3 | 0.010488 |
| CDCA4 | cell division cycle associated 4 | 0.0104769 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.0104752 |
| RNFT1 | ring finger protein, transmembrane 1 | 0.0104543 |
| ME2 | malic enzyme 2, NAD(+)-dependent, mitochondrial | 0.0104406 |
| RAB32 | RAB32, member RAS oncogene family | 0.0104035 |
| YIPF5 | Yip1 domain family, member 5 | 0.0102459 |
| PERP | PERP, TP53 apoptosis effector | 0.01023 |
| OAT | ornithine aminotransferase | 0.010178 |
| CNTN1 | contactin 1 | 0.0101614 |
| F13A1 | coagulation factor XIII, A1 polypeptide | 0.0101379 |
| ATP6V1G1 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 | 0.0101241 |
| S100A2 | S100 calcium binding protein A2 | 0.0101094 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | 0.010086 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | 0.0100811 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | 0.0100617 |
| PEX3 | peroxisomal biogenesis factor 3 | 0.0100501 |
| KLF6 | Kruppel-like factor 6 | 0.0099716 |
| BMP4 | bone morphogenetic protein 4 | 0.00991656 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | 0.00986852 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0098532 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.00985102 |
| MCL1 | myeloid cell leukemia 1 | 0.00974967 |
| REEP5 | receptor accessory protein 5 | 0.00965021 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.00961426 |
| CLDN10 | claudin 10 | 0.00958166 |
| HACD1 | 3-hydroxyacyl-CoA dehydratase 1 | 0.00951822 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 0.00948862 |
| MRPL13 | mitochondrial ribosomal protein L13 | 0.00944141 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.0094178 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.00938719 |
| PHACTR2 | phosphatase and actin regulator 2 | 0.00936099 |
| NDUFB3 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa | 0.00935128 |
| KLK8 | kallikrein-related peptidase 8 | 0.00933184 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 | 0.00932736 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.00932201 |
| FOXC1 | forkhead box C1 | 0.00926174 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | 0.00922175 |
| PLK2 | polo-like kinase 2 | 0.00918221 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.00917121 |
| RSL24D1 | ribosomal L24 domain containing 1 | 0.00915967 |
| TRIM22 | tripartite motif containing 22 | 0.00907851 |
| DSG3 | desmoglein 3 | 0.00907176 |
| HHEX | hematopoietically expressed homeobox | 0.00906671 |
| S100A8 | S100 calcium binding protein A8 | 0.00904469 |
| IFI44L | interferon-induced protein 44-like | 0.00903311 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.00900902 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.00895825 |
| PLSCR4 | phospholipid scramblase 4 | 0.00895424 |
| LYRM2 | LYR motif containing 2 | 0.00893636 |
| DEFB1 | defensin, beta 1 | 0.00891439 |
| PEG3 | paternally expressed 3 | 0.00888942 |
| DAZAP2 | DAZ associated protein 2 | 0.00888693 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.00886282 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 0.00883289 |
| ITGA6 | integrin, alpha 6 | 0.00883051 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.0088292 |
| RAB1A | RAB1A, member RAS oncogene family | 0.00882543 |
| S100A10 | S100 calcium binding protein A10 | 0.00881478 |
| EREG | epiregulin | 0.00880286 |
| HBB | hemoglobin, beta | 0.00879386 |
| CYB5R2 | cytochrome b5 reductase 2 | 0.00877406 |
| TMEM70 | transmembrane protein 70 | 0.00876277 |
| TSPAN5 | tetraspanin 5 | 0.00873071 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.00872924 |
| ST6GALNAC5 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 | 0.00870489 |
| CHI3L2 | chitinase 3-like 2 | 0.00870309 |
| TSPO | translocator protein (18kDa) | 0.00870208 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.00867575 |
| RND3 | Rho family GTPase 3 | 0.00865097 |
| IFNGR1 | interferon gamma receptor 1 | 0.00861763 |
| ZNF91 | zinc finger protein 91 | 0.00859721 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | 0.00859309 |
| MYOF | myoferlin | 0.00859265 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.00858853 |
| RIDA | reactive intermediate imine deaminase A homolog | 0.00858217 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | 0.00854937 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.00851134 |
| COMMD10 | COMM domain containing 10 | 0.00850481 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.00850166 |
| RPP14 | ribonuclease P/MRP 14kDa subunit | 0.00845687 |
| TPBG | trophoblast glycoprotein | 0.00845115 |
| PPA1 | pyrophosphatase (inorganic) 1 | 0.00844754 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit | 0.00844595 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.00843704 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.00842361 |
| LEPROT | leptin receptor overlapping transcript | 0.00841441 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.00841255 |
| IL18 | interleukin 18 | 0.00840032 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.00834852 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.00834686 |
| ANXA2P2 | annexin A2 pseudogene 2 | 0.00834015 |
| ZMAT3 | zinc finger, matrin-type 3 | 0.00833136 |
| ITM2A | integral membrane protein 2A | 0.00831047 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.00829279 |
| HOPX | HOP homeobox | 0.00827823 |
| NMD3 | NMD3 ribosome export adaptor | 0.00826642 |
| CANX | calnexin | 0.00823576 |
| PCLAF | PCNA clamp associated factor | 0.00823378 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.00822529 |
| NDUFS4 | NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) | 0.00819257 |
| ANXA2 | annexin A2 | 0.00818372 |
| CHMP2B | charged multivesicular body protein 2B | 0.00818114 |
| MYO1C | myosin IC | 0.00816983 |
| MRPL42 | mitochondrial ribosomal protein L42 | 0.00814491 |
| SH3GLB1 | SH3-domain GRB2-like endophilin B1 | 0.00814169 |
| TUBB2A | tubulin, beta 2A class IIa | 0.00811454 |
| ATP5MG | ATP synthase membrane subunit g | 0.00809803 |
| GLIPR1 | GLI pathogenesis-related 1 | 0.00809111 |
| MYO1B | myosin IB | 0.00807954 |
| PNO1 | partner of NOB1 homolog (S. cerevisiae) | 0.00807851 |
| PLEK | pleckstrin | 0.00803586 |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase | 0.00803205 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.00800808 |
| DSC2 | desmocollin 2 | 0.00800666 |
| POLR2K | polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa | 0.00796842 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | 0.00795217 |
| RHOH | ras homolog family member H | 0.0079127 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.00791197 |
| PTS | 6-pyruvoyltetrahydropterin synthase | 0.00790207 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 | 0.00789887 |
| FHL2 | four and a half LIM domains 2 | 0.00788435 |
| COX7B | cytochrome c oxidase subunit VIIb | 0.00786981 |
| MT1E | metallothionein 1E | 0.00786551 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0078361 |
| STX7 | syntaxin 7 | 0.00782331 |
| GPM6B | glycoprotein M6B | 0.00779296 |
| SLC38A2 | solute carrier family 38, member 2 | 0.00776839 |
| RAB9A | RAB9A, member RAS oncogene family | 0.0077572 |
| DUSP1 | dual specificity phosphatase 1 | 0.00774007 |
| OSMR | oncostatin M receptor | 0.0077397 |
| VSIG4 | V-set and immunoglobulin domain containing 4 | 0.00772635 |
| MOCS2 | molybdenum cofactor synthesis 2 | 0.00771595 |
| PTRH2 | peptidyl-tRNA hydrolase 2 | 0.00770974 |
| PTHLH | parathyroid hormone-like hormone | 0.00770861 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0077054 |
| RAB3GAP2 | RAB3 GTPase activating protein subunit 2 (non-catalytic) | 0.00770191 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.00768975 |
| CCL14 | chemokine (C-C motif) ligand 14 | 0.00768432 |
| MRPL18 | mitochondrial ribosomal protein L18 | 0.00767402 |
| CPVL | carboxypeptidase, vitellogenic-like | 0.00764946 |
| FOLR1 | folate receptor 1 (adult) | 0.00762786 |
| PPP4R3A | protein phosphatase 4 regulatory subunit 3A | 0.00762034 |
| METRN | meteorin, glial cell differentiation regulator | 0.00759747 |
| ENY2 | enhancer of yellow 2 homolog (Drosophila) | 0.00756808 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) | 0.00754562 |
| NOP10 | NOP10 ribonucleoprotein | 0.00754533 |
| ECHDC1 | ethylmalonyl-CoA decarboxylase 1 | 0.00751175 |
| ARL5A | ADP-ribosylation factor-like 5A | 0.00749784 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.00749132 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.00746631 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.00745416 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.00745372 |
| STOM | stomatin | 0.00744954 |
| ATP5F1C | ATP synthase F1 subunit gamma | 0.0074319 |
| SPRR1B | small proline-rich protein 1B | 0.00742037 |
| VAMP8 | vesicle-associated membrane protein 8 | 0.00741915 |
| DUSP11 | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) | 0.00740444 |
| CALD1 | caldesmon 1 | 0.00740192 |
| GLRX3 | glutaredoxin 3 | 0.00739763 |
| NEK7 | NIMA-related kinase 7 | 0.0073959 |
| ATF3 | activating transcription factor 3 | 0.00739123 |
| CCDC6 | coiled-coil domain containing 6 | 0.00737348 |
| TPD52 | tumor protein D52 | 0.00737117 |
| SCARB2 | scavenger receptor class B, member 2 | 0.00736108 |
| NSA2 | NSA2 ribosome biogenesis homolog (S. cerevisiae) | 0.00735288 |
| ATP5MJ | ATP synthase membrane subunit j | 0.00734547 |
| ARL1 | ADP-ribosylation factor-like 1 | 0.00734199 |
| TAF9 | TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa | 0.0073375 |
| THBD | thrombomodulin | 0.00733463 |
| SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A | 0.00731755 |
| B3GALNT1 | beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) | 0.00731213 |
| HMOX1 | heme oxygenase 1 | 0.00730254 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.00729185 |
| AIM2 | absent in melanoma 2 | 0.00729026 |
| NRCAM | neuronal cell adhesion molecule | 0.00728222 |
| DNASE2 | deoxyribonuclease II, lysosomal | 0.00725398 |
| MRPL39 | mitochondrial ribosomal protein L39 | 0.00723425 |
| MCUB | mitochondrial calcium uniporter dominant negative subunit beta | 0.00722284 |
| LXN | latexin | 0.00720931 |
| CD14 | CD14 molecule | 0.00720921 |
| ARMT1 | acidic residue methyltransferase 1 | 0.00720636 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | 0.00720406 |
| ADA | adenosine deaminase | 0.0071873 |
| PKP2 | plakophilin 2 | 0.00717923 |
| GAS1 | growth arrest-specific 1 | 0.00717382 |
| TSPAN13 | tetraspanin 13 | 0.00717121 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.00716869 |
| SPRR2B | small proline-rich protein 2B | 0.00716302 |
| HSPE1 | heat shock 10kDa protein 1 | 0.00715948 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0237294 |
| WDR7 | WD repeat domain 7 | -0.0187615 |
| OLFM4 | olfactomedin 4 | -0.0156466 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.0152972 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.0151756 |
| VEGFA | vascular endothelial growth factor A | -0.0135599 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.0130891 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0130341 |
| COL9A2 | collagen, type IX, alpha 2 | -0.0120265 |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit | -0.0118257 |
| BRCA1 | breast cancer 1, early onset | -0.0117164 |
| SYNGR3 | synaptogyrin 3 | -0.0112787 |
| TBCD | tubulin folding cofactor D | -0.0106992 |
| FASN | fatty acid synthase | -0.0105003 |
| TUBB2B | tubulin, beta 2B class IIb | -0.0103588 |
| RTN1 | reticulon 1 | -0.0103464 |
| JCHAIN | joining chain of multimeric IgA and IgM | -0.0102543 |
| FBLN1 | fibulin 1 | -0.0102359 |
| RRBP1 | ribosome binding protein 1 | -0.010227 |
| KLK3 | kallikrein-related peptidase 3 | -0.0102122 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0101838 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | -0.0100661 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.0100143 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.00990127 |
| MMP12 | matrix metallopeptidase 12 | -0.0097567 |
| SFTPA2 | surfactant protein A2 | -0.00967801 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.00967448 |
| KIAA0930 | KIAA0930 | -0.00960748 |
| A2M | alpha-2-macroglobulin | -0.00957279 |
| TFF3 | trefoil factor 3 (intestinal) | -0.00956162 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | -0.00955805 |
| KLK2 | kallikrein-related peptidase 2 | -0.00949673 |
| DIPK1A | divergent protein kinase domain 1A | -0.00949307 |
| PENK | proenkephalin | -0.00944656 |
| CHKB | choline kinase beta | -0.00944084 |
| CCNI | cyclin I | -0.00940268 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | -0.00930622 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.00928196 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.00900716 |
| TGM2 | transglutaminase 2 | -0.00895407 |
| GPD1L | glycerol-3-phosphate dehydrogenase 1-like | -0.00891093 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist | -0.00890942 |
| JPT2 | Jupiter microtubule associated homolog 2 | -0.00887127 |
| SDC1 | syndecan 1 | -0.00879724 |
| ACP3 | acid phosphatase 3 | -0.00878724 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.00877853 |
| PCP4 | Purkinje cell protein 4 | -0.00875503 |
| SIDT2 | SID1 transmembrane family, member 2 | -0.00873015 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | -0.00871218 |
| DCXR | dicarbonyl/L-xylulose reductase | -0.00871021 |
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 | -0.00867585 |
| MDC1 | mediator of DNA-damage checkpoint 1 | -0.00864379 |
| PRKCA | protein kinase C, alpha | -0.00859317 |
| WNT5B | wingless-type MMTV integration site family, member 5B | -0.00845414 |
| REPIN1 | replication initiator 1 | -0.00845005 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.00839278 |
| EPHB2 | EPH receptor B2 | -0.00839243 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.00834383 |
| MOXD1 | monooxygenase, DBH-like 1 | -0.00832371 |
| DGS2 | DiGeorge syndrome/velocardiofacial syndrome complex 2 | -0.00827598 |
| LRP4 | low density lipoprotein receptor-related protein 4 | -0.00826639 |
| TMSB15A | thymosin beta 15a | -0.00826348 |
| MED22 | mediator complex subunit 22 | -0.00825593 |
| TCIRG1 | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 | -0.00822512 |
| GUSB | glucuronidase, beta | -0.00819774 |
| AGR2 | anterior gradient 2 | -0.00808883 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | -0.00805918 |
| COL7A1 | collagen, type VII, alpha 1 | -0.00797222 |
| LRRC15 | leucine rich repeat containing 15 | -0.00795367 |
| ZBTB18 | zinc finger and BTB domain containing 18 | -0.00790114 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -0.00788056 |
| TMX4 | thioredoxin-related transmembrane protein 4 | -0.00786203 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.00785715 |
| OGFOD3 | 2-oxoglutarate and iron-dependent oxygenase domain containing 3 | -0.00782785 |
| POU2AF1 | POU class 2 associating factor 1 | -0.00781499 |
| ADCY1 | adenylate cyclase 1 (brain) | -0.00780402 |
| ATP6V0E2 | ATPase, H+ transporting V0 subunit e2 | -0.00780056 |
| NVL | nuclear VCP-like | -0.00780021 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | -0.00778044 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.00777891 |
| IQCE | IQ motif containing E | -0.00774331 |
| GNAS | GNAS complex locus | -0.00772179 |
| PTN | pleiotrophin | -0.00771707 |
| SMTN | smoothelin | -0.00771299 |
| COCH | cochlin | -0.00770147 |
| NDUFS8 | NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) | -0.00769424 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.00768567 |
| MUC4 | mucin 4, cell surface associated | -0.00766439 |
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 | -0.00765883 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.00765647 |
| PLD3 | phospholipase D family, member 3 | -0.00764364 |
| GLOD4 | glyoxalase domain containing 4 | -0.00763047 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.00761535 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | -0.00757452 |
| MLPH | melanophilin | -0.00756563 |
| KDM1A | lysine (K)-specific demethylase 1A | -0.00756295 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.00756081 |
| AGRN | agrin | -0.00756021 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00753858 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 | -0.007524 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.00752279 |
| SLC38A10 | solute carrier family 38, member 10 | -0.00751319 |
| PRPF8 | pre-mRNA processing factor 8 | -0.0075113 |
| NCOR2 | nuclear receptor corepressor 2 | -0.00748333 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | -0.00748026 |
| KHSRP | KH-type splicing regulatory protein | -0.00747851 |
| TSPAN4 | tetraspanin 4 | -0.00744655 |
| MICALL2 | MICAL-like 2 | -0.00743678 |
| ARG2 | arginase 2 | -0.00742657 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | -0.00742161 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.00741308 |
| PNPLA6 | patatin-like phospholipase domain containing 6 | -0.00739031 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | -0.0073899 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.00738597 |
| MCOLN1 | mucolipin 1 | -0.00737564 |
| AEBP1 | AE binding protein 1 | -0.00733537 |
| KRT15 | keratin 15, type I | -0.00733051 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.0073251 |
| MCM5 | minichromosome maintenance complex component 5 | -0.00732275 |
| LIG1 | ligase I, DNA, ATP-dependent | -0.00729944 |
| SF3A2 | splicing factor 3a, subunit 2, 66kDa | -0.00729273 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | -0.00728875 |
| INTS1 | integrator complex subunit 1 | -0.00726901 |
| TECR | trans-2,3-enoyl-CoA reductase | -0.00726815 |
| MAOA | monoamine oxidase A | -0.00726568 |
| PDE4A | phosphodiesterase 4A, cAMP-specific | -0.00722686 |
| RAPSN | receptor-associated protein of the synapse | -0.00721632 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.00719066 |
| NME3 | NME/NM23 nucleoside diphosphate kinase 3 | -0.00719052 |
| VARS | valyl-tRNA synthetase | -0.0071841 |
| DENND2B | DENN domain containing 2B | -0.007177 |
| POLD1 | polymerase (DNA directed), delta 1, catalytic subunit | -0.00715163 |
| GEM | GTP binding protein overexpressed in skeletal muscle | -0.00714415 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) | -0.00712228 |
| NDC80 | NDC80 kinetochore complex component | -0.00710661 |
| MXRA7 | matrix-remodelling associated 7 | -0.00710538 |
| IQSEC1 | IQ motif and Sec7 domain 1 | -0.00710024 |
| SEMA4C | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C | -0.00709673 |
| COMP | cartilage oligomeric matrix protein | -0.00709597 |
| NARS1 | asparaginyl-tRNA synthetase 1 | -0.00708543 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0070615 |
| GSE1 | Gse1 coiled-coil protein | -0.00703042 |
| HDLBP | high density lipoprotein binding protein | -0.00701944 |
| TMC5 | transmembrane channel-like 5 | -0.00701497 |
| FOXM1 | forkhead box M1 | -0.00700998 |
| NBAS | neuroblastoma amplified sequence | -0.00696638 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.00696164 |
| PCYOX1L | prenylcysteine oxidase 1 like | -0.00695845 |
| FOLH1B | folate hydrolase 1B | -0.00695817 |
| TRIM28 | tripartite motif containing 28 | -0.00695666 |
| MSMB | microseminoprotein, beta- | -0.00693837 |
| STC1 | stanniocalcin 1 | -0.00692943 |
| SETBP1 | SET binding protein 1 | -0.0069257 |
| BGN | biglycan | -0.00691994 |
| NELL2 | NEL-like 2 (chicken) | -0.0069065 |
| CNPY3 | canopy FGF signaling regulator 3 | -0.00688842 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | -0.0068854 |
| TAPBP | TAP binding protein (tapasin) | -0.00688159 |
| LEFTY1 | left-right determination factor 1 | -0.00687857 |
| RNF144A | ring finger protein 144A | -0.00687785 |
| PRKCSH | protein kinase C substrate 80K-H | -0.00685298 |
| COL1A2 | collagen, type I, alpha 2 | -0.00684032 |
| AGPAT1 | 1-acylglycerol-3-phosphate O-acyltransferase 1 | -0.00683983 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.00679816 |
| GPI | glucose-6-phosphate isomerase | -0.00678124 |
| CIT | citron rho-interacting serine/threonine kinase | -0.00676892 |
| LMNB2 | lamin B2 | -0.00676238 |
| ABHD2 | abhydrolase domain containing 2 | -0.00675613 |
| TSC2 | tuberous sclerosis 2 | -0.006754 |
| AP2A2 | adaptor-related protein complex 2, alpha 2 subunit | -0.00674515 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.00674459 |
| CD38 | CD38 molecule | -0.00674278 |
| NARF | nuclear prelamin A recognition factor | -0.00672912 |
| NKX3-1 | NK3 homeobox 1 | -0.00672013 |
| FAM13A | family with sequence similarity 13, member A | -0.00671241 |
| NAGA | N-acetylgalactosaminidase, alpha- | -0.00668618 |
| XYLT1 | xylosyltransferase I | -0.00667934 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | -0.00661907 |
| MAZ | MYC-associated zinc finger protein (purine-binding transcription factor) | -0.00660725 |
| LONP1 | lon peptidase 1, mitochondrial | -0.0066071 |
| ZBED1 | zinc finger, BED-type containing 1 | -0.00660469 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.00658107 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.00656759 |
| SLC26A6 | solute carrier family 26 (anion exchanger), member 6 | -0.00656097 |
| VPS51 | vacuolar protein sorting 51 homolog (S. cerevisiae) | -0.0065412 |
| KIF4A | kinesin family member 4A | -0.00654059 |
| WBP2 | WW domain binding protein 2 | -0.00653762 |
| FADS1 | fatty acid desaturase 1 | -0.0065359 |
| NUCB1 | nucleobindin 1 | -0.00650654 |
| COL16A1 | collagen, type XVI, alpha 1 | -0.00649712 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.00649224 |
| DACH1 | dachshund family transcription factor 1 | -0.00649213 |
| GTSE1 | G-2 and S-phase expressed 1 | -0.00648519 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | -0.00648472 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 | -0.00647634 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | -0.00647237 |
| TADA2A | transcriptional adaptor 2A | -0.00645807 |
| NEO1 | neogenin 1 | -0.00644869 |
| KIF18B | kinesin family member 18B | -0.00644553 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | -0.00644521 |
| WDR13 | WD repeat domain 13 | -0.00642364 |
| FZD10 | frizzled class receptor 10 | -0.00642125 |
| CDK5RAP3 | CDK5 regulatory subunit associated protein 3 | -0.00641241 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 | -0.00640563 |
| CBS | cystathionine-beta-synthase | -0.00640419 |
| SV2A | synaptic vesicle glycoprotein 2A | -0.0063885 |
| CTDNEP1 | CTD nuclear envelope phosphatase 1 | -0.00638548 |
| FUS | FUS RNA binding protein | -0.0063837 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | -0.00637427 |
| GTPBP1 | GTP binding protein 1 | -0.00637123 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.00635852 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.00635766 |
| IL27RA | interleukin 27 receptor, alpha | -0.00634173 |
| CD1E | CD1e molecule | -0.00633926 |
| BCOR | BCL6 corepressor | -0.00633691 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | -0.00633595 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | -0.00633205 |
| RTN3 | reticulon 3 | -0.00632364 |
| CDC25B | cell division cycle 25B | -0.00632204 |
| XPO7 | exportin 7 | -0.00631146 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | -0.00630167 |
| TRRAP | transformation/transcription domain-associated protein | -0.0062955 |
| EHMT2 | euchromatic histone-lysine N-methyltransferase 2 | -0.00629135 |
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | -0.00627627 |
| FECH | ferrochelatase | -0.00627001 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | -0.00626865 |
| CIZ1 | CDKN1A interacting zinc finger protein 1 | -0.00625498 |
| TFF1 | trefoil factor 1 | -0.00623598 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.00623083 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | -0.00623046 |
| CS | citrate synthase | -0.00619976 |
| SYNM | synemin, intermediate filament protein | -0.00618281 |
| CCNF | cyclin F | -0.00617184 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.00616961 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.00616228 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 | -0.00615303 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.00614717 |
| PER2 | period circadian clock 2 | -0.00614646 |
| TUBA1A | tubulin, alpha 1a | -0.00614392 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | -0.00614102 |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 | -0.00614074 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous | -0.00613464 |
| ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 | -0.00611849 |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 | -0.00610769 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 | -0.00610083 |
| SIRT3 | sirtuin 3 | -0.00608249 |
| NR5A1 | nuclear receptor subfamily 5, group A, member 1 | -0.00607682 |
| KIFAP3 | kinesin-associated protein 3 | -0.00607207 |
| INSIG1 | insulin induced gene 1 | -0.00607188 |
| NSF | N-ethylmaleimide-sensitive factor | -0.00607184 |
