NF1 Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description neurofibromin 1|This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 4763)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_NF1
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Genes

169 co-expressed genes for NF1 from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
ABCB10 ATP-binding cassette, sub-family B (MDR/TAP), member 10
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ADCY3 adenylate cyclase 3
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
AFF2 AF4/FMR2 family, member 2
AGPS alkylglycerone phosphate synthase
AOC4P amine oxidase, copper containing 4, pseudogene
AQP5 aquaporin 5
AQP7 aquaporin 7
ARL3 ADP-ribosylation factor-like 3
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
BCL2 B-cell CLL/lymphoma 2
BMP10 bone morphogenetic protein 10
BRCA1 breast cancer 1, early onset
BRD1 bromodomain containing 1
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCKAR cholecystokinin A receptor
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CELA2B chymotrypsin-like elastase family, member 2B
CFH complement factor H
COLGALT2 collagen beta(1-O)galactosyltransferase 2
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CTRL chymotrypsin-like
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DAPK2 death-associated protein kinase 2
DKK4 dickkopf WNT signaling pathway inhibitor 4
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16
DOCK1 dedicator of cytokinesis 1
DPT dermatopontin
DTNA dystrobrevin, alpha
DTX4 deltex 4, E3 ubiquitin ligase
ELAVL2 ELAV like neuron-specific RNA binding protein 2
EN2 engrailed homeobox 2
EPHB2 EPH receptor B2
ERC1 ELKS/RAB6-interacting/CAST family member 1
ERCC4 excision repair cross-complementation group 4
ESR1 estrogen receptor 1
ETV3 ets variant 3
EXTL3 exostosin-like glycosyltransferase 3
FAM189A2 family with sequence similarity 189, member A2
FGF18 fibroblast growth factor 18
FIG4 FIG4 phosphoinositide 5-phosphatase
FLT1 fms-related tyrosine kinase 1
FNTB farnesyltransferase, CAAX box, beta
FOSL1 FOS-like antigen 1
FRY furry homolog (Drosophila)
FRYL FRY-like
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GJB5 gap junction protein, beta 5, 31.1kDa
GLE1 GLE1 RNA export mediator
GNPAT glyceronephosphate O-acyltransferase
GPATCH8 G patch domain containing 8
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GPR3 G protein-coupled receptor 3
GRIK5 glutamate receptor, ionotropic, kainate 5
GRIP2 glutamate receptor interacting protein 2
GSTM5 glutathione S-transferase mu 5
GTSE1 G-2 and S-phase expressed 1
HOXD13 homeobox D13
HOXD4 homeobox D4
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
IFT27 intraflagellar transport 27
IGKV7-3 immunoglobulin kappa variable 7-3 (pseudogene)
IL11RA interleukin 11 receptor, alpha
IL13 interleukin 13
IL16 interleukin 16
IRF2 interferon regulatory factor 2
IRS2 insulin receptor substrate 2
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
JRK Jrk homolog (mouse)
KANK3 KN motif and ankyrin repeat domains 3
KLHL18 kelch-like family member 18
KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast)
KRT2 keratin 2, type II
KRT33A keratin 33A, type I
KRT33B keratin 33B, type I
KRT86 keratin 86, type II
LBP lipopolysaccharide binding protein
LEFTY1 left-right determination factor 1
LPGAT1 lysophosphatidylglycerol acyltransferase 1
LRRC48 leucine rich repeat containing 48
LTBP4 latent transforming growth factor beta binding protein 4
LY9 lymphocyte antigen 9
MAGEA9 melanoma antigen family A9
MC5R melanocortin 5 receptor
MFN1 mitofusin 1
MLN motilin
MSH3 mutS homolog 3
MSL3 male-specific lethal 3 homolog (Drosophila)
MSX1 msh homeobox 1
MT4 metallothionein 4
MYO9B myosin IXB
NEUROD2 neuronal differentiation 2
NF1 neurofibromin 1
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NFX1 nuclear transcription factor, X-box binding 1
NOS2 nitric oxide synthase 2, inducible
NR1I2 nuclear receptor subfamily 1, group I, member 2
NRP2 neuropilin 2
NRTN neurturin
NTNG2 netrin G2
NXPE3 neurexophilin and PC-esterase domain family, member 3
OPLAH 5-oxoprolinase (ATP-hydrolysing)
OPRL1 opiate receptor-like 1
P2RY10 purinergic receptor P2Y, G-protein coupled, 10
PAX9 paired box 9
PAXIP1 PAX interacting (with transcription-activation domain) protein 1
PDE4D phosphodiesterase 4D, cAMP-specific
PIGB phosphatidylinositol glycan anchor biosynthesis, class B
PIGR polymeric immunoglobulin receptor
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
POFUT2 protein O-fucosyltransferase 2
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
POU6F1 POU class 6 homeobox 1
POU6F2 POU class 6 homeobox 2
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PSG1 pregnancy specific beta-1-glycoprotein 1
PVR poliovirus receptor
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RREB1 ras responsive element binding protein 1
RXRG retinoid X receptor, gamma
SCAPER S-phase cyclin A-associated protein in the ER
SIM2 single-minded family bHLH transcription factor 2
SKI SKI proto-oncogene
SLC13A2 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1
SLC22A6 solute carrier family 22 (organic anion transporter), member 6
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC4A3 solute carrier family 4 (anion exchanger), member 3
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11
SLC6A7 solute carrier family 6 (neurotransmitter transporter), member 7
SMYD5 SMYD family member 5
SP140 SP140 nuclear body protein
SPEF1 sperm flagellar 1
STK17A serine/threonine kinase 17a
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SULT4A1 sulfotransferase family 4A, member 1
SYT5 synaptotagmin V
TBC1D22A TBC1 domain family, member 22A
TBX19 T-box 19
TBX5 T-box 5
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2)
TMEM11 transmembrane protein 11
TMPRSS6 transmembrane protease, serine 6
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRIM24 tripartite motif containing 24
TSSK2 testis-specific serine kinase 2
WBP4 WW domain binding protein 4
WT1 Wilms tumor 1
ZBTB22 zinc finger and BTB domain containing 22
ZNF133 zinc finger protein 133
ZNF266 zinc finger protein 266
ZNF500 zinc finger protein 500
ZNF592 zinc finger protein 592
ZP2 zona pellucida glycoprotein 2 (sperm receptor)