NF1 Gene Set

Dataset	NURSA Protein-Protein Interactions
Category	proteomics
Type	interacting protein
Description	neurofibromin 1\|This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 4763)
External Link	http://www.ncbi.nlm.nih.gov/gene/4763
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Genes

11 interacting proteins for NF1 from the NURSA Protein-Protein Interactions dataset.

Symbol	Name	Standardized Value
DIRAS2	DIRAS family, GTP-binding RAS-like 2	0.295526
TBC1D15	TBC1 domain family, member 15	0.125248
FADD	Fas (TNFRSF6)-associated via death domain	0.120694
ZNF609	zinc finger protein 609	0.086042
RFX7	regulatory factor X, 7	0.085268
RFXAP	regulatory factor X-associated protein	0.085268
CLPP	caseinolytic mitochondrial matrix peptidase proteolytic subunit	0.081964
RFX5	regulatory factor X, 5 (influences HLA class II expression)	0.081964
RABEP2	rabaptin, RAB GTPase binding effector protein 2	0.081964
RFXANK	regulatory factor X-associated ankyrin-containing protein	0.081964
GNL3	guanine nucleotide binding protein-like 3 (nucleolar)	0.017119