| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | neurofibromin 2 (merlin)|This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. This gene product has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport. This gene is expressed at high levels during embryonic development; in adults, significant expression is found in Schwann cells, meningeal cells, lens and nerve. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. Two predominant isoforms and a number of minor isoforms are produced by alternatively spliced transcripts. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 4771) |
| External Link | https://ncbi.nlm.nih.gov/gene/4771 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the NF2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.0127401 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.0125497 |
| S100A8 | S100 calcium binding protein A8 | 0.0122021 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 0.0121082 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | 0.0119692 |
| MAGEA3 | melanoma antigen family A3 | 0.0118052 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.0114984 |
| PRAME | preferentially expressed antigen in melanoma | 0.0114399 |
| TSPAN4 | tetraspanin 4 | 0.0112732 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.0108597 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0107346 |
| MAP7 | microtubule-associated protein 7 | 0.0106564 |
| CCL19 | chemokine (C-C motif) ligand 19 | 0.00997863 |
| MREG | melanoregulin | 0.00994616 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.00994484 |
| NXN | nucleoredoxin | 0.00946435 |
| ADAMDEC1 | ADAM-like, decysin 1 | 0.00944729 |
| GNAS | GNAS complex locus | 0.00944527 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | 0.00944457 |
| S100A9 | S100 calcium binding protein A9 | 0.00934873 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | 0.00933187 |
| NMU | neuromedin U | 0.00921455 |
| CHN1 | chimerin 1 | 0.00882618 |
| SFTPD | surfactant protein D | 0.00878555 |
| ODC1 | ornithine decarboxylase 1 | 0.00864353 |
| TFRC | transferrin receptor | 0.00855078 |
| DYNLL1 | dynein, light chain, LC8-type 1 | 0.00846318 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0084447 |
| CA2 | carbonic anhydrase II | 0.00842405 |
| RRAGA | Ras-related GTP binding A | 0.00838946 |
| KRT17 | keratin 17, type I | 0.00836861 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | 0.0082807 |
| SLC38A1 | solute carrier family 38, member 1 | 0.00821795 |
| KRT6A | keratin 6A, type II | 0.00792181 |
| INHBB | inhibin, beta B | 0.00789793 |
| NNMT | nicotinamide N-methyltransferase | 0.00785532 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.00780488 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.00778624 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | 0.00771888 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.00771488 |
| S100A2 | S100 calcium binding protein A2 | 0.00763405 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | 0.00754492 |
| GREM1 | gremlin 1, DAN family BMP antagonist | 0.00753365 |
| SFTPB | surfactant protein B | 0.00753152 |
| TGM2 | transglutaminase 2 | 0.00747091 |
| BTBD3 | BTB (POZ) domain containing 3 | 0.00733412 |
| CDC20 | cell division cycle 20 | 0.00728952 |
| SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | 0.00728208 |
| TATDN2 | TatD DNase domain containing 2 | 0.00724291 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.00720219 |
| PLK1 | polo-like kinase 1 | 0.0071606 |
| AURKB | aurora kinase B | 0.00711417 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | 0.0071105 |
| WDR7 | WD repeat domain 7 | 0.00708822 |
| LRP12 | low density lipoprotein receptor-related protein 12 | 0.00705236 |
| TACC3 | transforming, acidic coiled-coil containing protein 3 | 0.00704862 |
| HMGN3 | high mobility group nucleosomal binding domain 3 | 0.00702617 |
| BAD | BCL2-associated agonist of cell death | 0.00695908 |
| SFTPC | surfactant protein C | 0.006946 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.00690169 |
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) | 0.00689475 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 | 0.0068811 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.00681221 |
| MAGEA12 | melanoma antigen family A12 | 0.00675035 |
| TMEM126B | transmembrane protein 126B | 0.00674442 |
| PITX1 | paired-like homeodomain 1 | 0.00674258 |
| CD52 | CD52 molecule | 0.0067177 |
| PPL | periplakin | 0.00671709 |
| TMEM70 | transmembrane protein 70 | 0.00670598 |
| WTAP | Wilms tumor 1 associated protein | 0.00666803 |
| KCMF1 | potassium channel modulatory factor 1 | 0.00663546 |
| ACKR1 | atypical chemokine receptor 1 (Duffy blood group) | 0.00662586 |
| TXNDC9 | thioredoxin domain containing 9 | 0.00658837 |
| TGFB1 | transforming growth factor, beta 1 | 0.00657975 |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 | 0.00657712 |
| STAM | signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 | 0.00655421 |
| ORC1 | origin recognition complex, subunit 1 | 0.00654021 |
| HACD1 | 3-hydroxyacyl-CoA dehydratase 1 | 0.00646992 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.00643822 |
| MMP9 | matrix metallopeptidase 9 | 0.00636988 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.00630425 |
| CCDC86 | coiled-coil domain containing 86 | 0.00629374 |
| FASN | fatty acid synthase | 0.00629105 |
| REXO2 | RNA exonuclease 2 | 0.00628922 |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 | 0.00628393 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.00626745 |
| TENT4A | terminal nucleotidyltransferase 4A | 0.00625748 |
| FASTKD3 | FAST kinase domains 3 | 0.00620813 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | 0.00620077 |
| NOL11 | nucleolar protein 11 | 0.00619324 |
| MAEA | macrophage erythroblast attacher | 0.00618317 |
| PDCD10 | programmed cell death 10 | 0.00616466 |
| GAL | galanin/GMAP prepropeptide | 0.00615737 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.00615545 |
| CD59 | CD59 molecule, complement regulatory protein | 0.00614126 |
| RGS13 | regulator of G-protein signaling 13 | 0.00611204 |
| HSPA4 | heat shock 70kDa protein 4 | 0.00610487 |
| IDH3A | isocitrate dehydrogenase 3 (NAD+) alpha | 0.00609446 |
| MAOA | monoamine oxidase A | 0.00609423 |
| MMADHC | methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria | 0.00609421 |
| NPY1R | neuropeptide Y receptor Y1 | 0.0060935 |
| HEBP2 | heme binding protein 2 | 0.00607486 |
| UXT | ubiquitously-expressed, prefoldin-like chaperone | 0.00605394 |
| SLC25A14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 | 0.00597754 |
| KRT6B | keratin 6B, type II | 0.00596922 |
| KCNK3 | potassium channel, two pore domain subfamily K, member 3 | 0.00596896 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.00596199 |
| VBP1 | von Hippel-Lindau binding protein 1 | 0.00594591 |
| DHCR7 | 7-dehydrocholesterol reductase | 0.00593928 |
| UCHL3 | ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) | 0.00593061 |
| MRPS12 | mitochondrial ribosomal protein S12 | 0.00591143 |
| PHF10 | PHD finger protein 10 | 0.00590746 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | 0.00587714 |
| TLCD3A | TLC domain containing 3A | 0.0058242 |
| ESPL1 | extra spindle pole bodies homolog 1 (S. cerevisiae) | 0.00581448 |
| CD2AP | CD2-associated protein | 0.00577339 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.00575476 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 0.00573975 |
| WASF1 | WAS protein family, member 1 | 0.00573887 |
| GCH1 | GTP cyclohydrolase 1 | 0.00573627 |
| TMEM14B | transmembrane protein 14B | 0.00573297 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.00571121 |
| PSMD6 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 | 0.00570977 |
| RNF6 | ring finger protein (C3H2C3 type) 6 | 0.00570754 |
| JPT2 | Jupiter microtubule associated homolog 2 | 0.00570373 |
| MOB4 | MOB family member 4, phocein | 0.00570189 |
| PRDX4 | peroxiredoxin 4 | 0.00569934 |
| LSM3 | LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00569841 |
| NDUFB6 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa | 0.00568333 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) | 0.00567754 |
| RWDD1 | RWD domain containing 1 | 0.00566726 |
| SLC29A1 | solute carrier family 29 (equilibrative nucleoside transporter), member 1 | 0.0056573 |
| EZR | ezrin | 0.0056511 |
| CKS1B | CDC28 protein kinase regulatory subunit 1B | 0.00565074 |
| OIP5 | Opa interacting protein 5 | 0.00562161 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha | 0.00561776 |
| SAC3D1 | SAC3 domain containing 1 | 0.00561626 |
| FASTKD1 | FAST kinase domains 1 | 0.00561151 |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 | 0.00560775 |
| SNX10 | sorting nexin 10 | 0.00559965 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | 0.00559474 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | 0.00558946 |
| CXADR | coxsackie virus and adenovirus receptor | 0.00558049 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.00557719 |
| CLGN | calmegin | 0.00556854 |
| CLEC2B | C-type lectin domain family 2, member B | 0.00556629 |
| DKK4 | dickkopf WNT signaling pathway inhibitor 4 | 0.00556002 |
| C1QA | complement component 1, q subcomponent, A chain | 0.00554244 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.00553269 |
| PDHX | pyruvate dehydrogenase complex, component X | 0.00553223 |
| CLEC10A | C-type lectin domain family 10, member A | 0.00552282 |
| CD163 | CD163 molecule | 0.00550117 |
| MAGEA4 | melanoma antigen family A4 | 0.0054923 |
| YIF1A | Yip1 interacting factor homolog A (S. cerevisiae) | 0.00547928 |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | 0.00547732 |
| CCNC | cyclin C | 0.00547537 |
| TXNL4A | thioredoxin-like 4A | 0.00546149 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | 0.00545617 |
| CD1E | CD1e molecule | 0.00542004 |
| LUM | lumican | 0.00541661 |
| TUBG1 | tubulin, gamma 1 | 0.00541234 |
| PKP1 | plakophilin 1 | 0.00540326 |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | 0.00540039 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 0.00538133 |
| IFT57 | intraflagellar transport 57 | 0.00532993 |
| RAB38 | RAB38, member RAS oncogene family | 0.00532867 |
| MRPL19 | mitochondrial ribosomal protein L19 | 0.00531911 |
| SOCS1 | suppressor of cytokine signaling 1 | 0.00529241 |
| PMF1 | polyamine-modulated factor 1 | 0.00529203 |
| MRPS30 | mitochondrial ribosomal protein S30 | 0.00528984 |
| MTERF3 | mitochondrial transcription termination factor 3 | 0.00526615 |
| E2F5 | E2F transcription factor 5, p130-binding | 0.00526251 |
| CHGA | chromogranin A | 0.00524773 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.00523045 |
| THOC6 | THO complex 6 | 0.00522254 |
| MMP11 | matrix metallopeptidase 11 | 0.00521972 |
| NRTN | neurturin | 0.00521745 |
| SPAG6 | sperm associated antigen 6 | 0.00520848 |
| OLA1 | Obg-like ATPase 1 | 0.00520442 |
| PARVB | parvin, beta | 0.00520242 |
| STMN1 | stathmin 1 | 0.0051996 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | 0.00519164 |
| TMSB15A | thymosin beta 15a | 0.0051875 |
| TTK | TTK protein kinase | 0.0051829 |
| ZNF512B | zinc finger protein 512B | 0.00517529 |
| MALL | mal, T-cell differentiation protein-like | 0.00516903 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | 0.00516412 |
| SFTPA2 | surfactant protein A2 | 0.00515182 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 0.00513745 |
| CD34 | CD34 molecule | 0.00513011 |
| COPS4 | COP9 signalosome subunit 4 | 0.00512984 |
| PSMD8 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 | 0.00512945 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0051237 |
| TPRKB | TP53RK binding protein | 0.00511346 |
| MRTO4 | mRNA turnover 4 homolog (S. cerevisiae) | 0.00510907 |
| TRIB3 | tribbles pseudokinase 3 | 0.00510686 |
| TTLL12 | tubulin tyrosine ligase-like family member 12 | 0.00508629 |
| NDUFAF4 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 | 0.00508418 |
| UBAP2L | ubiquitin associated protein 2-like | 0.00508372 |
| PHACTR2 | phosphatase and actin regulator 2 | 0.00507341 |
| RRP15 | ribosomal RNA processing 15 homolog (S. cerevisiae) | 0.00507235 |
| GNG10 | guanine nucleotide binding protein (G protein), gamma 10 | 0.00506728 |
| MRPL42 | mitochondrial ribosomal protein L42 | 0.0050541 |
| MYO1D | myosin ID | 0.00504441 |
| CUL1 | cullin 1 | 0.00504294 |
| ORC4 | origin recognition complex, subunit 4 | 0.00503592 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.00503064 |
| MED28 | mediator complex subunit 28 | 0.00502858 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | 0.00502077 |
| RAN | RAN, member RAS oncogene family | 0.00501142 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 | 0.00500821 |
| HDDC2 | HD domain containing 2 | 0.00499105 |
| PRELID3B | PRELI domain containing 3B | 0.00498344 |
| CD200 | CD200 molecule | 0.00497884 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.00497639 |
| PAX6 | paired box 6 | 0.00497395 |
| CDC34 | cell division cycle 34 | 0.00496844 |
| CDKN3 | cyclin-dependent kinase inhibitor 3 | 0.00496828 |
| PAEP | progestagen-associated endometrial protein | 0.00496651 |
| PTH2R | parathyroid hormone 2 receptor | 0.00496335 |
| MMP7 | matrix metallopeptidase 7 | 0.0049508 |
| TMEM259 | transmembrane protein 259 | 0.00494483 |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 | 0.00491766 |
| TFEC | transcription factor EC | 0.00491513 |
| TESK1 | testis-specific kinase 1 | 0.00491325 |
| HP | haptoglobin | 0.00491234 |
| GIMAP6 | GTPase, IMAP family member 6 | 0.00490866 |
| VSIG4 | V-set and immunoglobulin domain containing 4 | 0.00490765 |
| ALG5 | ALG5, dolichyl-phosphate beta-glucosyltransferase | 0.00489522 |
| MIOS | missing oocyte, meiosis regulator, homolog (Drosophila) | 0.00489077 |
| DESI1 | desumoylating isopeptidase 1 | 0.00487776 |
| ALDOA | aldolase A, fructose-bisphosphate | 0.00487114 |
| FST | follistatin | 0.00486702 |
| TCF4 | transcription factor 4 | 0.00485363 |
| DXO | decapping exoribonuclease | 0.00484734 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.00483879 |
| SYNGR3 | synaptogyrin 3 | 0.0048317 |
| RAD51C | RAD51 paralog C | 0.00482797 |
| TRMT1 | tRNA methyltransferase 1 homolog (S. cerevisiae) | 0.00482305 |
| RSL24D1 | ribosomal L24 domain containing 1 | 0.00481948 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.00481757 |
| TSPAN13 | tetraspanin 13 | 0.00480353 |
| DSC2 | desmocollin 2 | 0.00479741 |
| ASPN | asporin | 0.00479621 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | 0.00479484 |
| TARBP2 | TAR (HIV-1) RNA binding protein 2 | 0.00479005 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 0.00477482 |
| EMC3 | ER membrane protein complex subunit 3 | 0.00477294 |
| RCHY1 | ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase | 0.00477262 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LCN2 | lipocalin 2 | -0.0164959 |
| ADD3 | adducin 3 (gamma) | -0.0144109 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0142259 |
| AOC1 | amine oxidase, copper containing 1 | -0.0135128 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.013422 |
| METRN | meteorin, glial cell differentiation regulator | -0.0131973 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0130802 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0128571 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0125879 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0123349 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | -0.0121711 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | -0.0119816 |
| IFI44L | interferon-induced protein 44-like | -0.0117287 |
| CYBA | cytochrome b-245, alpha polypeptide | -0.0116578 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0114902 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0111051 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0110916 |
| MT1E | metallothionein 1E | -0.0110194 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.0109202 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | -0.0108014 |
| FCGBP | Fc fragment of IgG binding protein | -0.0107265 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 | -0.0107015 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | -0.0106945 |
| PADI2 | peptidyl arginine deiminase, type II | -0.0106472 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0106313 |
| GOLGA8H | golgin A8 family, member H | -0.0104301 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -0.0102257 |
| COL14A1 | collagen, type XIV, alpha 1 | -0.0101949 |
| APOD | apolipoprotein D | -0.0101773 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.00991699 |
| FGF1 | fibroblast growth factor 1 (acidic) | -0.00985638 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | -0.0098084 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.00960114 |
| ABAT | 4-aminobutyrate aminotransferase | -0.00952204 |
| TRIM22 | tripartite motif containing 22 | -0.00948275 |
| GPR137B | G protein-coupled receptor 137B | -0.00944633 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.00944349 |
| MX1 | MX dynamin-like GTPase 1 | -0.00943208 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.00937661 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.00937541 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | -0.00936875 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.00933239 |
| ZMAT3 | zinc finger, matrin-type 3 | -0.00931507 |
| GPM6B | glycoprotein M6B | -0.0091941 |
| G0S2 | G0/G1 switch 2 | -0.00918775 |
| KLK6 | kallikrein-related peptidase 6 | -0.00905712 |
| COL9A3 | collagen, type IX, alpha 3 | -0.00903668 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.00898387 |
| DACH1 | dachshund family transcription factor 1 | -0.00893523 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | -0.00890104 |
| PMP2 | peripheral myelin protein 2 | -0.00886704 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.00884323 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | -0.00883047 |
| THBS1 | thrombospondin 1 | -0.00880152 |
| CFI | complement factor I | -0.00879361 |
| CRYAB | crystallin, alpha B | -0.0087474 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.00872425 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | -0.00867233 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | -0.00863682 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.00863425 |
| IL1B | interleukin 1, beta | -0.00858096 |
| PLLP | plasmolipin | -0.00855713 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.00853628 |
| ITM2C | integral membrane protein 2C | -0.00851963 |
| WASHC4 | WASH complex subunit 4 | -0.00846633 |
| TSPAN8 | tetraspanin 8 | -0.0084533 |
| MT1X | metallothionein 1X | -0.00844322 |
| FAM107A | family with sequence similarity 107, member A | -0.00841072 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 | -0.00840867 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.00838011 |
| SRPX | sushi-repeat containing protein, X-linked | -0.00837357 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | -0.0083444 |
| CES1 | carboxylesterase 1 | -0.00833449 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.00831072 |
| BCAS1 | breast carcinoma amplified sequence 1 | -0.00829774 |
| GPX1 | glutathione peroxidase 1 | -0.00828817 |
| CHD7 | chromodomain helicase DNA binding protein 7 | -0.00826127 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.00824141 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | -0.00822679 |
| SH3YL1 | SH3 and SYLF domain containing 1 | -0.00815203 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | -0.00811863 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | -0.00808775 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | -0.00806044 |
| SFRP4 | secreted frizzled-related protein 4 | -0.00800915 |
| ADIRF | adipogenesis regulatory factor | -0.00796623 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.00796437 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | -0.00796019 |
| FAXDC2 | fatty acid hydroxylase domain containing 2 | -0.00795183 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.00791475 |
| DEFB1 | defensin, beta 1 | -0.00788127 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.00784202 |
| METTL7A | methyltransferase like 7A | -0.00781677 |
| PTGES | prostaglandin E synthase | -0.00778796 |
| PLK2 | polo-like kinase 2 | -0.00778635 |
| CCN2 | cellular communication network factor 2 | -0.00777952 |
| IL2RG | interleukin 2 receptor, gamma | -0.0077482 |
| AREG | amphiregulin | -0.00774117 |
| ARMCX2 | armadillo repeat containing, X-linked 2 | -0.00772704 |
| NMRK1 | nicotinamide riboside kinase 1 | -0.00770019 |
| BTK | Bruton agammaglobulinemia tyrosine kinase | -0.00768024 |
| HNMT | histamine N-methyltransferase | -0.00767988 |
| SOBP | sine oculis binding protein homolog (Drosophila) | -0.00766126 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.00765587 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -0.00764912 |
| PEG3 | paternally expressed 3 | -0.00763667 |
| DPEP1 | dipeptidase 1 (renal) | -0.00761466 |
| NDRG2 | NDRG family member 2 | -0.00759934 |
| CD9 | CD9 molecule | -0.00757553 |
| MCAM | melanoma cell adhesion molecule | -0.00757321 |
| SQSTM1 | sequestosome 1 | -0.00756233 |
| MT1H | metallothionein 1H | -0.00755037 |
| DDX11 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 | -0.0075433 |
| PLAT | plasminogen activator, tissue | -0.00754045 |
| NID2 | nidogen 2 (osteonidogen) | -0.0075205 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | -0.00751297 |
| BIN1 | bridging integrator 1 | -0.0075034 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | -0.0074751 |
| MT1F | metallothionein 1F | -0.00745588 |
| ADGRG1 | adhesion G protein-coupled receptor G1 | -0.0074141 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | -0.00740757 |
| OAT | ornithine aminotransferase | -0.00740242 |
| SLC16A4 | solute carrier family 16, member 4 | -0.00739984 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | -0.00736704 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 | -0.00734646 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 | -0.00733271 |
| TJP2 | tight junction protein 2 | -0.00732905 |
| PLAUR | plasminogen activator, urokinase receptor | -0.00728791 |
| NAV2 | neuron navigator 2 | -0.00724258 |
| RAP2A | RAP2A, member of RAS oncogene family | -0.00724171 |
| SERINC5 | serine incorporator 5 | -0.00723722 |
| EPHB2 | EPH receptor B2 | -0.00721206 |
| GPR183 | G protein-coupled receptor 183 | -0.00719937 |
| ISLR | immunoglobulin superfamily containing leucine-rich repeat | -0.00718024 |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 | -0.00717999 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -0.00717961 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | -0.00712115 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.00710612 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.00710502 |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 | -0.0070943 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.00707351 |
| CSRP1 | cysteine and glycine-rich protein 1 | -0.0070564 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.00703337 |
| ZCCHC24 | zinc finger, CCHC domain containing 24 | -0.00702708 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | -0.00701462 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.00698552 |
| GDF15 | growth differentiation factor 15 | -0.00698301 |
| S100P | S100 calcium binding protein P | -0.00696725 |
| DUSP4 | dual specificity phosphatase 4 | -0.00695216 |
| IRF9 | interferon regulatory factor 9 | -0.00694642 |
| CALB1 | calbindin 1, 28kDa | -0.00692562 |
| PTN | pleiotrophin | -0.00692013 |
| SLC22A18 | solute carrier family 22, member 18 | -0.00690368 |
| TBX3 | T-box 3 | -0.00689857 |
| CCL4 | chemokine (C-C motif) ligand 4 | -0.00689443 |
| S100A6 | S100 calcium binding protein A6 | -0.00688367 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.00687855 |
| BST2 | bone marrow stromal cell antigen 2 | -0.0068713 |
| NCAN | neurocan | -0.006863 |
| ATP10B | ATPase, class V, type 10B | -0.00686284 |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing | -0.00685522 |
| AHNAK | AHNAK nucleoprotein | -0.00684408 |
| LAPTM5 | lysosomal protein transmembrane 5 | -0.00682872 |
| ENPP4 | ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) | -0.00682342 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.00679556 |
| CRABP1 | cellular retinoic acid binding protein 1 | -0.0067794 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide | -0.00677858 |
| TMEM100 | transmembrane protein 100 | -0.00677786 |
| NFASC | neurofascin | -0.00677143 |
| MX2 | MX dynamin-like GTPase 2 | -0.00676819 |
| MT1HL1 | metallothionein 1H-like 1 | -0.00675268 |
| EGR3 | early growth response 3 | -0.00674515 |
| CDC14B | cell division cycle 14B | -0.00673685 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | -0.00673312 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.00670478 |
| GPM6A | glycoprotein M6A | -0.00670072 |
| BLNK | B-cell linker | -0.00668912 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.00667616 |
| HIP1 | huntingtin interacting protein 1 | -0.0066706 |
| CST7 | cystatin F (leukocystatin) | -0.00666529 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.00666278 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.00665327 |
| RAB40B | RAB40B, member RAS oncogene family | -0.00664758 |
| OLFM4 | olfactomedin 4 | -0.00663274 |
| PEBP1 | phosphatidylethanolamine binding protein 1 | -0.00662848 |
| BAMBI | BMP and activin membrane-bound inhibitor | -0.00662633 |
| ANK2 | ankyrin 2, neuronal | -0.00661822 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | -0.00661686 |
| TSPAN1 | tetraspanin 1 | -0.00657913 |
| SCG5 | secretogranin V | -0.00657668 |
| CAPN3 | calpain 3, (p94) | -0.0065711 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.00655425 |
| LPXN | leupaxin | -0.00654961 |
| KRT23 | keratin 23, type I | -0.00654445 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.00654021 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.00653544 |
| HBEGF | heparin-binding EGF-like growth factor | -0.0065247 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.00650708 |
| MAGED2 | melanoma antigen family D2 | -0.00650431 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | -0.0064917 |
| ASS1 | argininosuccinate synthase 1 | -0.00648886 |
| VAV3 | vav 3 guanine nucleotide exchange factor | -0.00647569 |
| PNMA2 | paraneoplastic Ma antigen 2 | -0.00647345 |
| GPX2 | glutathione peroxidase 2 | -0.00646282 |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 | -0.00645665 |
| LEFTY1 | left-right determination factor 1 | -0.00643787 |
| RGS1 | regulator of G-protein signaling 1 | -0.00642952 |
| RNF167 | ring finger protein 167 | -0.00642032 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | -0.0064077 |
| PTCH1 | patched 1 | -0.00639239 |
| IL1R1 | interleukin 1 receptor, type I | -0.00639141 |
| IER3 | immediate early response 3 | -0.00638379 |
| AFF1 | AF4/FMR2 family, member 1 | -0.00637256 |
| PRR5L | proline rich 5 like | -0.00633691 |
| LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) | -0.00633053 |
| RNASE3 | ribonuclease, RNase A family, 3 | -0.00631478 |
| LITAF | lipopolysaccharide-induced TNF factor | -0.00629801 |
| SOX10 | SRY (sex determining region Y)-box 10 | -0.00628141 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.00627523 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.00626753 |
| TFF3 | trefoil factor 3 (intestinal) | -0.0062642 |
| ANXA6 | annexin A6 | -0.00626269 |
| FAR2 | fatty acyl CoA reductase 2 | -0.00625103 |
| NKG7 | natural killer cell granule protein 7 | -0.00625077 |
| FAM171A1 | family with sequence similarity 171, member A1 | -0.006239 |
| GAS1 | growth arrest-specific 1 | -0.00623474 |
| PDGFRL | platelet-derived growth factor receptor-like | -0.0062317 |
| HSPA12A | heat shock 70kDa protein 12A | -0.00622264 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta | -0.00622134 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | -0.00622016 |
| FABP1 | fatty acid binding protein 1, liver | -0.00620953 |
| ALAD | aminolevulinate dehydratase | -0.00620863 |
| IFITM2 | interferon induced transmembrane protein 2 | -0.00620859 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.00618742 |
| NES | nestin | -0.00618154 |
| COX15 | cytochrome c oxidase assembly homolog 15 (yeast) | -0.00617573 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor | -0.00617275 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.00613812 |
| ZIC1 | Zic family member 1 | -0.00613379 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) | -0.00612617 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | -0.00612526 |
| TRIM8 | tripartite motif containing 8 | -0.00612444 |
| RHOB | ras homolog family member B | -0.00611998 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | -0.00611769 |
| ABLIM1 | actin binding LIM protein 1 | -0.00611717 |
| CAPG | capping protein (actin filament), gelsolin-like | -0.00611345 |
| RCAN1 | regulator of calcineurin 1 | -0.0061086 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.00608579 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | -0.00608529 |
| LONP2 | lon peptidase 2, peroxisomal | -0.00606977 |
| TNIK | TRAF2 and NCK interacting kinase | -0.00606569 |
