NFAT5 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description nuclear factor of activated T-cells 5, tonicity-responsive|The product of this gene is a member of the nuclear factors of activated T cells family of transcription factors. Proteins belonging to this family play a central role in inducible gene transcription during the immune response. This protein regulates gene expression induced by osmotic stress in mammalian cells. Unlike monomeric members of this protein family, this protein exists as a homodimer and forms stable dimers with DNA elements. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 10725)
External Link http://www.ncbi.nlm.nih.gov/gene/10725
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156 interacting proteins for NFAT5 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
AHCY adenosylhomocysteinase
ALMS1 Alstrom syndrome protein 1
ALYREF Aly/REF export factor
ANAPC1 anaphase promoting complex subunit 1
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ASPH aspartate beta-hydroxylase
ATM ATM serine/threonine kinase
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CAMK2D calcium/calmodulin-dependent protein kinase II delta
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
CDK5 cyclin-dependent kinase 5
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase
CNBP CCHC-type zinc finger, nucleic acid binding protein
CSNK1A1 casein kinase 1, alpha 1
CSNK1A1L casein kinase 1, alpha 1-like
DDB1 damage-specific DNA binding protein 1, 127kDa
DDB2 damage-specific DNA binding protein 2, 48kDa
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9
DOHH deoxyhypusine hydroxylase/monooxygenase
EIF3A eukaryotic translation initiation factor 3, subunit A
EIF3B eukaryotic translation initiation factor 3, subunit B
EIF3C eukaryotic translation initiation factor 3, subunit C
EIF3D eukaryotic translation initiation factor 3, subunit D
EIF3E eukaryotic translation initiation factor 3, subunit E
EIF3F eukaryotic translation initiation factor 3, subunit F
EIF3K eukaryotic translation initiation factor 3, subunit K
EIF3L eukaryotic translation initiation factor 3, subunit L
EIF3M eukaryotic translation initiation factor 3, subunit M
EML3 echinoderm microtubule associated protein like 3
EPPK1 epiplakin 1
FBL fibrillarin
FKBP4 FK506 binding protein 4, 59kDa
FLAD1 flavin adenine dinucleotide synthetase 1
FN1 fibronectin 1
FOXC1 forkhead box C1
FOXK1 forkhead box K1
FOXP3 forkhead box P3
GLUD1 glutamate dehydrogenase 1
GOLGA1 golgin A1
H1F0 H1 histone family, member 0
H1FX H1 histone family, member X
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2
HIST1H1B histone cluster 1, H1b
HIST1H1C histone cluster 1, H1c
HIST1H1E histone cluster 1, H1e
HIST1H4F histone cluster 1, H4f
HMGA1 high mobility group AT-hook 1
HMGA2 high mobility group AT-hook 2
HMGB2 high mobility group box 2
HMGB3 high mobility group box 3
HNF1A HNF1 homeobox A
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HSPA8 heat shock 70kDa protein 8
KIFC1 kinesin family member C1
LIG3 ligase III, DNA, ATP-dependent
LIMD1 LIM domains containing 1
LYZ lysozyme
MACF1 microtubule-actin crosslinking factor 1
MAX MYC associated factor X
MCL1 myeloid cell leukemia 1
MGME1 mitochondrial genome maintenance exonuclease 1
MPG N-methylpurine-DNA glycosylase
MRPS23 mitochondrial ribosomal protein S23
MSH2 mutS homolog 2
MSH3 mutS homolog 3
MSH6 mutS homolog 6
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFU1 NFU1 iron-sulfur cluster scaffold
OSBPL3 oxysterol binding protein-like 3
OSBPL6 oxysterol binding protein-like 6
PARP1 poly (ADP-ribose) polymerase 1
PARP2 poly (ADP-ribose) polymerase 2
PARP4 poly (ADP-ribose) polymerase family, member 4
PLCG1 phospholipase C, gamma 1
PNKP polynucleotide kinase 3'-phosphatase
POLE polymerase (DNA directed), epsilon, catalytic subunit
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit
POLG polymerase (DNA directed), gamma
POLR1C polymerase (RNA) I polypeptide C, 30kDa
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
POLR2H polymerase (RNA) II (DNA directed) polypeptide H
POLR3A polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
POLR3B polymerase (RNA) III (DNA directed) polypeptide B
POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD)
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
POLR3E polymerase (RNA) III (DNA directed) polypeptide E (80kD)
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
POLR3H polymerase (RNA) III (DNA directed) polypeptide H (22.9kD)
POU2F1 POU class 2 homeobox 1
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PUM2 pumilio RNA-binding family member 2
RBM39 RNA binding motif protein 39
REPIN1 replication initiator 1
RFC1 replication factor C (activator 1) 1, 145kDa
RFC2 replication factor C (activator 1) 2, 40kDa
RFC3 replication factor C (activator 1) 3, 38kDa
RFC4 replication factor C (activator 1) 4, 37kDa
RFC5 replication factor C (activator 1) 5, 36.5kDa
RPA1 replication protein A1, 70kDa
RPA2 replication protein A2, 32kDa
RPA3 replication protein A3, 14kDa
RPL17 ribosomal protein L17
RPL23 ribosomal protein L23
RPL23A ribosomal protein L23a
RPL24 ribosomal protein L24
RPL31 ribosomal protein L31
RPL35 ribosomal protein L35
RPL38 ribosomal protein L38
RPS10 ribosomal protein S10
RPS11 ribosomal protein S11
RPS15A ribosomal protein S15a
RPS23 ribosomal protein S23
RPS25 ribosomal protein S25
RPS26 ribosomal protein S26
RPS3 ribosomal protein S3
RPS4X ribosomal protein S4, X-linked
RPS4Y2 ribosomal protein S4, Y-linked 2
RPS6 ribosomal protein S6
RPS7 ribosomal protein S7
SARS seryl-tRNA synthetase
SET SET nuclear proto-oncogene
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SOX9 SRY (sex determining region Y)-box 9
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein)
SRP9 signal recognition particle 9kDa
SSB Sjogren syndrome antigen B (autoantigen La)
SSBP1 single-stranded DNA binding protein 1, mitochondrial
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1
SUB1 SUB1 homolog (S. cerevisiae)
SUMO2 small ubiquitin-like modifier 2
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TBC1D4 TBC1 domain family, member 4
TFAM transcription factor A, mitochondrial
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TOP1 topoisomerase (DNA) I
TRMT6 tRNA methyltransferase 6
TRPS1 trichorhinophalangeal syndrome I
UBR4 ubiquitin protein ligase E3 component n-recognin 4
VBP1 von Hippel-Lindau binding protein 1
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
YBX1 Y box binding protein 1
YBX3 Y box binding protein 3