NFATC1 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1|The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes. [provided by RefSeq, Jul 2013] (NCBI Entrez Gene Database, 4772)
External Link https://ncbi.nlm.nih.gov/gene/4772
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Genes

500 genes differentially expressed following the NFATC1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
XIC X chromosome inactivation center 0.0129914
AUTS2 autism susceptibility candidate 2 0.011592
TARP TCR gamma alternate reading frame protein 0.0105072
HSPB1 heat shock 27kDa protein 1 0.0104407
CLC Charcot-Leyden crystal galectin 0.0103528
PBX3 pre-B-cell leukemia homeobox 3 0.00976111
FCGBP Fc fragment of IgG binding protein 0.00912452
PRUNE2 prune homolog 2 (Drosophila) 0.00890189
FERMT1 fermitin family member 1 0.00874392
FBP1 fructose-1,6-bisphosphatase 1 0.00850526
AQP3 aquaporin 3 (Gill blood group) 0.00842617
PON3 paraoxonase 3 0.00842213
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 0.00827034
LY75 lymphocyte antigen 75 0.00821092
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.00814594
ALOX5AP arachidonate 5-lipoxygenase-activating protein 0.00802901
ITGA8 integrin, alpha 8 0.00792951
EFNB2 ephrin-B2 0.00792057
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.00783358
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 0.00774849
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial 0.00771885
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 0.00771403
NDRG1 N-myc downstream regulated 1 0.00767727
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.00763525
DHFR dihydrofolate reductase 0.00762518
TFPI2 tissue factor pathway inhibitor 2 0.00762097
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.00761427
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 0.00750697
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.00750021
ADD3 adducin 3 (gamma) 0.00746355
ACAT2 acetyl-CoA acetyltransferase 2 0.00739416
AOC1 amine oxidase, copper containing 1 0.0073804
PCYOX1 prenylcysteine oxidase 1 0.00729383
DEFA4 defensin, alpha 4, corticostatin 0.00719556
KLK11 kallikrein-related peptidase 11 0.00719445
ATP10B ATPase, class V, type 10B 0.00715636
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.00707975
INAVA innate immunity activator 0.00707675
SMC1A structural maintenance of chromosomes 1A 0.00706049
HDAC6 histone deacetylase 6 0.00705252
HTRA1 HtrA serine peptidase 1 0.0070479
NAV2 neuron navigator 2 0.00702224
TARBP1 TAR (HIV-1) RNA binding protein 1 0.00700647
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.00699324
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.00692894
IGLL1 immunoglobulin lambda-like polypeptide 1 0.00686617
ARG1 arginase 1 0.00675948
RFC2 replication factor C (activator 1) 2, 40kDa 0.00672822
BHMT betaine--homocysteine S-methyltransferase 0.00670526
COL9A2 collagen, type IX, alpha 2 0.00666622
ZNF160 zinc finger protein 160 0.00666021
HIP1 huntingtin interacting protein 1 0.00665472
NPIPB3 nuclear pore complex interacting protein family, member B3 0.00651482
IL2RG interleukin 2 receptor, gamma 0.0065083
DCT dopachrome tautomerase 0.00650152
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.00647666
ZNF721 zinc finger protein 721 0.00645037
BPI bactericidal/permeability-increasing protein 0.00642572
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 0.00640554
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.00638341
PRKCH protein kinase C, eta 0.00637188
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 0.00635852
NOX1 NADPH oxidase 1 0.00632677
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 0.00631751
CDH17 cadherin 17, LI cadherin (liver-intestine) 0.00628991
RRM1 ribonucleotide reductase M1 0.00627732
MARCKS myristoylated alanine-rich protein kinase C substrate 0.00625936
MAST4 microtubule associated serine/threonine kinase family member 4 0.00623358
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 0.00621632
DIAPH2 diaphanous-related formin 2 0.006214
LDOC1 leucine zipper, down-regulated in cancer 1 0.00620804
INSM1 insulinoma-associated 1 0.00620634
KCNK5 potassium channel, two pore domain subfamily K, member 5 0.00617889
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 0.00616309
MAP7 microtubule-associated protein 7 0.00615498
TCF7 transcription factor 7 (T-cell specific, HMG-box) 0.0061158
CST7 cystatin F (leukocystatin) 0.00610917
SYNJ2 synaptojanin 2 0.0060783
NANOG Nanog homeobox 0.00606522
WNT5B wingless-type MMTV integration site family, member 5B 0.00599394
KRT1 keratin 1, type II 0.00597245
CTSD cathepsin D 0.00595659
BAMBI BMP and activin membrane-bound inhibitor 0.00593919
EPHX2 epoxide hydrolase 2, cytoplasmic 0.00591093
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.00588787
S100A12 S100 calcium binding protein A12 0.00585639
JMJD6 jumonji domain containing 6 0.00585003
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 0.00584865
NOP56 NOP56 ribonucleoprotein 0.00583486
DENND1B DENN/MADD domain containing 1B 0.00578263
CA12 carbonic anhydrase XII 0.00575559
CXADR coxsackie virus and adenovirus receptor 0.00573718
ERAP2 endoplasmic reticulum aminopeptidase 2 0.0057132
FGFBP1 fibroblast growth factor binding protein 1 0.00569488
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 0.00569183
BMP2 bone morphogenetic protein 2 0.00568772
SLC17A3 solute carrier family 17 (organic anion transporter), member 3 0.00565557
LYZ lysozyme 0.00564621
NBPF10 neuroblastoma breakpoint family, member 10 0.00563894
PRKCA protein kinase C, alpha 0.0056314
GOLGA8H golgin A8 family, member H 0.00559585
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor 0.00559521
SHB Src homology 2 domain containing adaptor protein B 0.00557143
GUSBP3 glucuronidase, beta pseudogene 3 0.00556436
KIF21B kinesin family member 21B 0.00556423
SDC1 syndecan 1 0.0055351
CGA glycoprotein hormones, alpha polypeptide 0.00551392
AAMDC adipogenesis associated, Mth938 domain containing 0.00550492
LARS1 leucyl-tRNA synthetase 1 0.00549914
PARM1 prostate androgen-regulated mucin-like protein 1 0.00547459
RBM8A RNA binding motif protein 8A 0.00545238
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 0.00542659
EPX eosinophil peroxidase 0.00541908
LRP2 low density lipoprotein receptor-related protein 2 0.00539893
CDHR1 cadherin-related family member 1 0.00538886
IPO9 importin 9 0.00538446
SLC38A10 solute carrier family 38, member 10 0.00538001
HBD hemoglobin, delta 0.0053785
NSG1 neuron specific gene family member 1 0.00536352
PRR11 proline rich 11 0.00536024
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) 0.00534933
ZNF430 zinc finger protein 430 0.005341
CXCL3 chemokine (C-X-C motif) ligand 3 0.0053233
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 0.00532191
LAS1L LAS1-like (S. cerevisiae) 0.00531083
TXNIP thioredoxin interacting protein 0.00529058
IL10RB interleukin 10 receptor, beta 0.00528281
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila) 0.00528126
PCSK1 proprotein convertase subtilisin/kexin type 1 0.00526671
SH3YL1 SH3 and SYLF domain containing 1 0.00525383
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) 0.00523985
CLDN3 claudin 3 0.00523983
ANXA3 annexin A3 0.00523242
MMP8 matrix metallopeptidase 8 0.00520557
ZNF91 zinc finger protein 91 0.00519974
UPB1 ureidopropionase, beta 0.00519312
COL1A2 collagen, type I, alpha 2 0.00519251
KLK10 kallikrein-related peptidase 10 0.0051801
ERBB2 erb-b2 receptor tyrosine kinase 2 0.00517991
LMO3 LIM domain only 3 (rhombotin-like 2) 0.0051791
FABP1 fatty acid binding protein 1, liver 0.00517826
PRTN3 proteinase 3 0.00517424
CCN2 cellular communication network factor 2 0.00516853
PTK2B protein tyrosine kinase 2 beta 0.005165
KCTD12 potassium channel tetramerization domain containing 12 0.00513719
COLEC11 collectin sub-family member 11 0.00513121
IPO13 importin 13 0.00512849
MYB v-myb avian myeloblastosis viral oncogene homolog 0.00512694
TYRP1 tyrosinase-related protein 1 0.00508719
RAB27A RAB27A, member RAS oncogene family 0.00506958
GNG4 guanine nucleotide binding protein (G protein), gamma 4 0.00506719
HAUS2 HAUS augmin-like complex, subunit 2 0.00506689
ZNF611 zinc finger protein 611 0.00506515
ZNF665 zinc finger protein 665 0.00506054
ZFP36 ZFP36 ring finger protein 0.00505975
FBXW12 F-box and WD repeat domain containing 12 0.00505649
CTBP2 C-terminal binding protein 2 0.00505568
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3 0.00504832
NVL nuclear VCP-like 0.00503795
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 0.00502663
ACAA2 acetyl-CoA acyltransferase 2 0.00502245
PTPRK protein tyrosine phosphatase, receptor type, K 0.00501982
PRKCQ protein kinase C, theta 0.00500729
BGN biglycan 0.00500196
FXYD2 FXYD domain containing ion transport regulator 2 0.00499724
ELANE elastase, neutrophil expressed 0.00499268
CYFIP2 cytoplasmic FMR1 interacting protein 2 0.00498409
KIF3B kinesin family member 3B 0.00497315
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 0.00496852
RNASE3 ribonuclease, RNase A family, 3 0.00496813
TIMELESS timeless circadian clock 0.00496696
ARMCX2 armadillo repeat containing, X-linked 2 0.00496357
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 0.00495136
CDA cytidine deaminase 0.00493441
PMEL premelanosome protein 0.00491971
IFNAR1 interferon (alpha, beta and omega) receptor 1 0.00491958
ACOX2 acyl-CoA oxidase 2, branched chain 0.00491387
PDLIM1 PDZ and LIM domain 1 0.00490666
AP1G2 adaptor-related protein complex 1, gamma 2 subunit 0.0049064
DSG1 desmoglein 1 0.00490322
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 0.00489205
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 0.00488511
H2AX H2A.X variant histone 0.0048832
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.00485608
SRPRA SRP receptor subunit alpha 0.00484717
STX3 syntaxin 3 0.00483664
SCRIB scribbled planar cell polarity protein 0.00483594
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.00482859
ALCAM activated leukocyte cell adhesion molecule 0.00482227
CAPN3 calpain 3, (p94) 0.0048215
CLIP2 CAP-GLY domain containing linker protein 2 0.00479508
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 0.00478946
MGAM maltase-glucoamylase 0.00478613
IL7R interleukin 7 receptor 0.00478071
RRBP1 ribosome binding protein 1 0.00477109
ADD2 adducin 2 (beta) 0.00476691
LTB lymphotoxin beta (TNF superfamily, member 3) 0.00476142
PGAM1 phosphoglycerate mutase 1 (brain) 0.00474805
ZMYND8 zinc finger, MYND-type containing 8 0.00474783
LGALS4 lectin, galactoside-binding, soluble, 4 0.00474566
COCH cochlin 0.00472974
GPA33 glycoprotein A33 (transmembrane) 0.00472854
RND3 Rho family GTPase 3 0.00472236
CTSS cathepsin S 0.00471546
RIN3 Ras and Rab interactor 3 0.00471147
KIF11 kinesin family member 11 0.00470026
CLEC5A C-type lectin domain family 5, member A 0.00469855
LRP4 low density lipoprotein receptor-related protein 4 0.00469609
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase 0.00469525
IVNS1ABP influenza virus NS1A binding protein 0.00469443
DSC1 desmocollin 1 0.00469101
ILVBL ilvB (bacterial acetolactate synthase)-like 0.00467829
ACTN1 actinin, alpha 1 0.00466541
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.00465986
GAS6 growth arrest-specific 6 0.00465579
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 0.00464373
CA9 carbonic anhydrase IX 0.00464211
KLHDC8A kelch domain containing 8A 0.00462655
NR1I2 nuclear receptor subfamily 1, group I, member 2 0.00462311
RNF43 ring finger protein 43 0.00461193
VIL1 villin 1 0.00460754
CD1A CD1a molecule 0.0046045
POF1B premature ovarian failure, 1B 0.00460345
NDNF neuron-derived neurotrophic factor 0.00459976
DUSP8 dual specificity phosphatase 8 0.00458704
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 0.0045738
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 0.00455535
KLF7 Kruppel-like factor 7 (ubiquitous) 0.00455096
KAT6B K(lysine) acetyltransferase 6B 0.0045363
VNN1 vanin 1 0.00450191
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.00449489
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 0.00448942
FCN1 ficolin (collagen/fibrinogen domain containing) 1 0.00448803
CD8A CD8a molecule 0.00448728
BCAS3 breast carcinoma amplified sequence 3 0.00448473
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa 0.00448089
SYNPO synaptopodin 0.00447673
CBX1 chromobox homolog 1 0.00447571
CBX7 chromobox homolog 7 0.00447065
MAP2K7 mitogen-activated protein kinase kinase 7 0.00446297
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2 0.00445609
TRIM44 tripartite motif containing 44 0.00443009
GBA3 glucosidase, beta, acid 3 (gene/pseudogene) 0.00442919
BCAT2 branched chain amino-acid transaminase 2, mitochondrial 0.00442155
ATP5PD ATP synthase peripheral stalk subunit d 0.00441993
ENG endoglin 0.00441185
ESM1 endothelial cell-specific molecule 1 0.00441098
CHGB chromogranin B 0.00440885
RGS1 regulator of G-protein signaling 1 0.00440882
CES1 carboxylesterase 1 0.00439379

decreased expression

Symbol Name Standardized Value
ASPN asporin -0.0169768
DCN decorin -0.013829
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.0137274
FABP4 fatty acid binding protein 4, adipocyte -0.0131516
ADO 2-aminoethanethiol (cysteamine) dioxygenase -0.0130438
CARMIL1 capping protein regulator and myosin 1 linker 1 -0.0128297
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide -0.0123487
FBLN1 fibulin 1 -0.012017
LUM lumican -0.011723
EGR2 early growth response 2 -0.0117069
C1S complement component 1, s subcomponent -0.011343
CHRDL1 chordin-like 1 -0.0110904
CD36 CD36 molecule (thrombospondin receptor) -0.0109604
APOD apolipoprotein D -0.0104891
RNPS1 RNA binding protein S1, serine-rich domain -0.0101827
ECM2 extracellular matrix protein 2, female organ and adipocyte specific -0.0101641
KRT19 keratin 19, type I -0.0099258
COL15A1 collagen, type XV, alpha 1 -0.0096862
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 -0.0096671
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -0.00935577
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) -0.00934802
MFAP5 microfibrillar associated protein 5 -0.00931125
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -0.00927787
OSR2 odd-skipped related transciption factor 2 -0.00915712
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.00912133
KRT17 keratin 17, type I -0.00884174
MT1M metallothionein 1M -0.00876758
G0S2 G0/G1 switch 2 -0.0087533
MMP11 matrix metallopeptidase 11 -0.0087525
PMP22 peripheral myelin protein 22 -0.00857207
CXCL13 chemokine (C-X-C motif) ligand 13 -0.008566
BAG2 BCL2-associated athanogene 2 -0.00855869
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 -0.00850403
PDGFRL platelet-derived growth factor receptor-like -0.00848396
GULP1 GULP, engulfment adaptor PTB domain containing 1 -0.00844593
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 -0.00843183
SLC30A1 solute carrier family 30 (zinc transporter), member 1 -0.00838836
NPY1R neuropeptide Y receptor Y1 -0.00830483
MYBPC1 myosin binding protein C, slow type -0.00829534
ETNK1 ethanolamine kinase 1 -0.00816977
SFRP1 secreted frizzled-related protein 1 -0.00811341
CHIC2 cysteine-rich hydrophobic domain 2 -0.00802939
VCAN versican -0.00801393
MMP7 matrix metallopeptidase 7 -0.00785677
SLC19A2 solute carrier family 19 (thiamine transporter), member 2 -0.00775923
LCP1 lymphocyte cytosolic protein 1 (L-plastin) -0.00773176
OGN osteoglycin -0.00773074
C1QTNF3 C1q and tumor necrosis factor related protein 3 -0.00772222
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -0.00769832
METRN meteorin, glial cell differentiation regulator -0.007598
COL14A1 collagen, type XIV, alpha 1 -0.00759222
ANXA5 annexin A5 -0.00758897
LAMA2 laminin, alpha 2 -0.00755719
CEL carboxyl ester lipase -0.0074807
PLTP phospholipid transfer protein -0.00740852
SRPX sushi-repeat containing protein, X-linked -0.00737844
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 -0.00737733
NNMT nicotinamide N-methyltransferase -0.00728699
MFAP4 microfibrillar-associated protein 4 -0.00727748
C1R complement component 1, r subcomponent -0.00726472
SPINK1 serine peptidase inhibitor, Kazal type 1 -0.00720886
SUB1 SUB1 homolog (S. cerevisiae) -0.00720681
ADIPOQ adiponectin, C1Q and collagen domain containing -0.00712787
MIR22HG MIR22 host gene -0.00712555
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 -0.00709329
ASNS asparagine synthetase (glutamine-hydrolyzing) -0.0070834
NUPR1 nuclear protein, transcriptional regulator, 1 -0.00708305
LOX lysyl oxidase -0.00705067
MT1X metallothionein 1X -0.00695464
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 -0.0068447
GPX1 glutathione peroxidase 1 -0.00681688
DPT dermatopontin -0.00681524
GAS1 growth arrest-specific 1 -0.00680096
LHFP lipoma HMGIC fusion partner -0.00675885
TMEM165 transmembrane protein 165 -0.00674564
CHN1 chimerin 1 -0.0067451
GEM GTP binding protein overexpressed in skeletal muscle -0.00673806
JAM2 junctional adhesion molecule 2 -0.006707
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -0.00669782
LPAR1 lysophosphatidic acid receptor 1 -0.00669247
MT1F metallothionein 1F -0.00667405
C3 complement component 3 -0.00661817
MMP1 matrix metallopeptidase 1 -0.00661432
TGIF1 TGFB-induced factor homeobox 1 -0.00657453
SPON2 spondin 2, extracellular matrix protein -0.00653595
CTSK cathepsin K -0.00653508
SECTM1 secreted and transmembrane 1 -0.00652927
AMDHD2 amidohydrolase domain containing 2 -0.00652662
GMDS GDP-mannose 4,6-dehydratase -0.00652222
TMED5 transmembrane emp24 protein transport domain containing 5 -0.00652027
TSPAN13 tetraspanin 13 -0.00650287
NR2F1 nuclear receptor subfamily 2, group F, member 1 -0.00647717
KRT7 keratin 7, type II -0.00646639
SYT1 synaptotagmin I -0.00646564
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 -0.00646132
IGF1 insulin-like growth factor 1 (somatomedin C) -0.00645505
CCL8 chemokine (C-C motif) ligand 8 -0.0064284
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 -0.00642477
ACKR1 atypical chemokine receptor 1 (Duffy blood group) -0.00642249
PTN pleiotrophin -0.00638857
CTH cystathionine gamma-lyase -0.00636843
PTGIS prostaglandin I2 (prostacyclin) synthase -0.00633016
GOLM1 golgi membrane protein 1 -0.00626731
NPTXR neuronal pentraxin receptor -0.00626459
TPM2 tropomyosin 2 (beta) -0.00622737
CFH complement factor H -0.00618395
MAPK6 mitogen-activated protein kinase 6 -0.00615075
EGR1 early growth response 1 -0.00613039
FADS3 fatty acid desaturase 3 -0.0061061
MT1E metallothionein 1E -0.00609963
ZCCHC24 zinc finger, CCHC domain containing 24 -0.00605297
MITF microphthalmia-associated transcription factor -0.00604282
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase -0.00603987
BAALC brain and acute leukemia, cytoplasmic -0.0060165
UBE2S ubiquitin-conjugating enzyme E2S -0.00597598
ZNF267 zinc finger protein 267 -0.00596028
GABRP gamma-aminobutyric acid (GABA) A receptor, pi -0.00595737
SV2B synaptic vesicle glycoprotein 2B -0.00595046
MSX1 msh homeobox 1 -0.00594127
MSMB microseminoprotein, beta- -0.00594041
OMD osteomodulin -0.00593719
RGS13 regulator of G-protein signaling 13 -0.00593508
FBLN2 fibulin 2 -0.00592793
PPP1R15A protein phosphatase 1, regulatory subunit 15A -0.00592427
CD99 CD99 molecule -0.00591755
GPNMB glycoprotein (transmembrane) nmb -0.00590303
EMP1 epithelial membrane protein 1 -0.0058701
IL6 interleukin 6 -0.00584701
GTF2B general transcription factor IIB -0.00582919
S100A2 S100 calcium binding protein A2 -0.00582317
ANXA1 annexin A1 -0.00581539
AKAP12 A kinase (PRKA) anchor protein 12 -0.0058138
WTAP Wilms tumor 1 associated protein -0.00580453
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 -0.00579457
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 -0.00578714
TGM2 transglutaminase 2 -0.00576943
SYNM synemin, intermediate filament protein -0.00576351
CTSH cathepsin H -0.00574653
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -0.00572146
NDN necdin, melanoma antigen (MAGE) family member -0.00569942
ZEB1 zinc finger E-box binding homeobox 1 -0.00569796
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5 -0.00569328
SNX10 sorting nexin 10 -0.005692
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.00568504
CHP1 calcineurin-like EF-hand protein 1 -0.0056293
MUC5B mucin 5B, oligomeric mucus/gel-forming -0.00562119
PSAT1 phosphoserine aminotransferase 1 -0.00562016
PITX1 paired-like homeodomain 1 -0.00559145
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 -0.00557031
SPON1 spondin 1, extracellular matrix protein -0.00556691
S100P S100 calcium binding protein P -0.00556384
PFN2 profilin 2 -0.00555501
LMCD1 LIM and cysteine-rich domains 1 -0.00555327
PDE1A phosphodiesterase 1A, calmodulin-dependent -0.00554239
BAD BCL2-associated agonist of cell death -0.0055247
IL1R1 interleukin 1 receptor, type I -0.00552424
GRB14 growth factor receptor-bound protein 14 -0.0055091
KDSR 3-ketodihydrosphingosine reductase -0.005504
LMO2 LIM domain only 2 (rhombotin-like 1) -0.00550206
SPARCL1 SPARC-like 1 (hevin) -0.0054984
THAP9-AS1 THAP9 antisense RNA 1 -0.00549697
MOCOS molybdenum cofactor sulfurase -0.00549315
CST6 cystatin E/M -0.00548875
GRAMD2B GRAM domain containing 2B -0.00547841
STXBP2 syntaxin binding protein 2 -0.00547539
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 -0.00545995
MT3 metallothionein 3 -0.00544433
TBX3 T-box 3 -0.00543017
STC2 stanniocalcin 2 -0.00541183
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 -0.00540922
HIGD1A HIG1 hypoxia inducible domain family, member 1A -0.00540408
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 -0.00539686
RGCC regulator of cell cycle -0.00538145
INHBB inhibin, beta B -0.00537352
ABHD4 abhydrolase domain containing 4 -0.00536599
GFPT2 glutamine-fructose-6-phosphate transaminase 2 -0.00536086
TFRC transferrin receptor -0.00535703
ZNF410 zinc finger protein 410 -0.00535516
STOM stomatin -0.0053501
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C) -0.00534815
CLEC3B C-type lectin domain family 3, member B -0.00534674
CLDN1 claudin 1 -0.00533492
TMEM70 transmembrane protein 70 -0.00533261
NDP Norrie disease (pseudoglioma) -0.00532716
DAAM2 dishevelled associated activator of morphogenesis 2 -0.00532076
TPD52L1 tumor protein D52-like 1 -0.00530424
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 -0.00529661
TPSAB1 tryptase alpha/beta 1 -0.00528412
WASF1 WAS protein family, member 1 -0.00527849
ARHGAP12 Rho GTPase activating protein 12 -0.0052677
CLDND1 claudin domain containing 1 -0.00526055
TSC22D3 TSC22 domain family, member 3 -0.00525116
GSTM3 glutathione S-transferase mu 3 (brain) -0.00524458
FUT9 fucosyltransferase 9 (alpha (1,3) fucosyltransferase) -0.00523936
DSE dermatan sulfate epimerase -0.00521119
EIF1B eukaryotic translation initiation factor 1B -0.00520585
CAPN6 calpain 6 -0.00519698
GPC3 glypican 3 -0.00519675
GYG1 glycogenin 1 -0.00519
PTGER3 prostaglandin E receptor 3 (subtype EP3) -0.00518634
IQCG IQ motif containing G -0.00518456
COL5A2 collagen, type V, alpha 2 -0.00516358
MXRA5 matrix-remodelling associated 5 -0.0051567
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 -0.00515065
HMGN5 high mobility group nucleosome binding domain 5 -0.00512616
CFB complement factor B -0.00511379
SFRP4 secreted frizzled-related protein 4 -0.0051026
CNTN1 contactin 1 -0.00509718
MLF1 myeloid leukemia factor 1 -0.00509489
PRKCB protein kinase C, beta -0.00509382
ADIRF adipogenesis regulatory factor -0.00509253
FAM216A family with sequence similarity 216, member A -0.00508545
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 -0.00508411
HOMER1 homer scaffolding protein 1 -0.00507336
PTS 6-pyruvoyltetrahydropterin synthase -0.00507246
ASPH aspartate beta-hydroxylase -0.00505225
GSDME gasdermin E -0.00504862
TMEM135 transmembrane protein 135 -0.0050436
SAR1B secretion associated, Ras related GTPase 1B -0.00502985
PDE4DIP phosphodiesterase 4D interacting protein -0.00502395
HACD1 3-hydroxyacyl-CoA dehydratase 1 -0.00501391
MTA1 metastasis associated 1 -0.00501251
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha -0.00497332
ELOVL5 ELOVL fatty acid elongase 5 -0.00495591
DUSP10 dual specificity phosphatase 10 -0.00495127
PLAU plasminogen activator, urokinase -0.00494489
CBX6 chromobox homolog 6 -0.00491999
SDC2 syndecan 2 -0.00491064
IGFBP6 insulin-like growth factor binding protein 6 -0.00490682
SMAD3 SMAD family member 3 -0.00490222
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 -0.00488329
NRBF2 nuclear receptor binding factor 2 -0.00488217
FABP5 fatty acid binding protein 5 (psoriasis-associated) -0.00486979
MTERF3 mitochondrial transcription termination factor 3 -0.00484483
MCUB mitochondrial calcium uniporter dominant negative subunit beta -0.00484148
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) -0.00483698
INSIG1 insulin induced gene 1 -0.00482977
JMJD1C jumonji domain containing 1C -0.00482275
TXNL1 thioredoxin-like 1 -0.00481437
NR1H3 nuclear receptor subfamily 1, group H, member 3 -0.00480625
FZD6 frizzled class receptor 6 -0.00478296
TCF12 transcription factor 12 -0.00477339
SELENOF selenoprotein F -0.00476725
THAP10 THAP domain containing 10 -0.00476246
OSBPL8 oxysterol binding protein-like 8 -0.00474464
AMPH amphiphysin -0.00473744
ACYP2 acylphosphatase 2, muscle type -0.00473519
CEPT1 choline/ethanolamine phosphotransferase 1 -0.00471909
SPP1 secreted phosphoprotein 1 -0.00470441
SLC35G2 solute carrier family 35, member G2 -0.00469424