NFATC2 Gene Set

Dataset JASPAR Predicted Transcription Factor Targets
Category genomics
Type transcription factor
Description nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2|This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Apr 2012] (NCBI Entrez Gene Database, 4773)
External Link http://www.ncbi.nlm.nih.gov/gene/4773
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Genes

117 target genes of the NFATC2 transcription factor predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset.

Symbol Name
AFF3 AF4/FMR2 family, member 3
ARFGEF3 ARFGEF family member 3
BACE1 beta-site APP-cleaving enzyme 1
BCKDK branched chain ketoacid dehydrogenase kinase
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BRD4 bromodomain containing 4
C19ORF24 chromosome 19 open reading frame 24
CALD1 caldesmon 1
CCL20 chemokine (C-C motif) ligand 20
CCL4 chemokine (C-C motif) ligand 4
CCL4L1 chemokine (C-C motif) ligand 4-like 1
CCL4L2 chemokine (C-C motif) ligand 4-like 2
CD248 CD248 molecule, endosialin
CD3D CD3d molecule, delta (CD3-TCR complex)
CD3G CD3g molecule, gamma (CD3-TCR complex)
CD40LG CD40 ligand
CDK14 cyclin-dependent kinase 14
CDON cell adhesion associated, oncogene regulated
CFAP58 cilia and flagella associated protein 58
CGNL1 cingulin-like 1
CLEC5A C-type lectin domain family 5, member A
CNTN4 contactin 4
CPA3 carboxypeptidase A3 (mast cell)
CRYGA crystallin, gamma A
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DIRAS1 DIRAS family, GTP-binding RAS-like 1
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
EHD1 EH-domain containing 1
GABPB1 GA binding protein transcription factor, beta subunit 1
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GOT1L1 glutamic-oxaloacetic transaminase 1-like 1
GPATCH4 G patch domain containing 4
GPR12 G protein-coupled receptor 12
GPR155 G protein-coupled receptor 155
GSDMD gasdermin D
GSTO1 glutathione S-transferase omega 1
GUK1 guanylate kinase 1
GZMK granzyme K (granzyme 3; tryptase II)
H1FX H1 histone family, member X
HCLS1 hematopoietic cell-specific Lyn substrate 1
HEPACAM2 HEPACAM family member 2
HEYL hes-related family bHLH transcription factor with YRPW motif-like
IFNE interferon, epsilon
IGDCC4 immunoglobulin superfamily, DCC subclass, member 4
IGFL4 IGF-like family member 4
IL12RB2 interleukin 12 receptor, beta 2
IL17D interleukin 17D
IL2 interleukin 2
IL4 interleukin 4
IPO9 importin 9
IRF4 interferon regulatory factor 4
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KLHL20 kelch-like family member 20
LGALS3 lectin, galactoside-binding, soluble, 3
LIMCH1 LIM and calponin homology domains 1
LRRC4C leucine rich repeat containing 4C
LRRC69 leucine rich repeat containing 69
MALSU1 mitochondrial assembly of ribosomal large subunit 1
METTL22 methyltransferase like 22
MICU1 mitochondrial calcium uptake 1
MIMS1 mitochondrial inner membrane scaffold 1
MTMR10 myotubularin related protein 10
MVD mevalonate (diphospho) decarboxylase
MYH13 myosin, heavy chain 13, skeletal muscle
NACC1 nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
NCKAP5 NCK-associated protein 5
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NEK2 NIMA-related kinase 2
NINJ2 ninjurin 2
NLGN4Y neuroligin 4, Y-linked
NUPL1 nucleoporin like 1
OR2H2 olfactory receptor, family 2, subfamily H, member 2
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1
PLS1 plastin 1
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3
PTCH1 patched 1
PYGM phosphorylase, glycogen, muscle
RFX5 regulatory factor X, 5 (influences HLA class II expression)
RGS18 regulator of G-protein signaling 18
RLBP1 retinaldehyde binding protein 1
RPS23 ribosomal protein S23
SCGB1D4 secretoglobin, family 1D, member 4
SDCBP syndecan binding protein (syntenin)
SDR16C5 short chain dehydrogenase/reductase family 16C, member 5
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SESTD1 SEC14 and spectrin domains 1
SFMBT2 Scm-like with four mbt domains 2
SLC26A5 solute carrier family 26 (anion exchanger), member 5
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SMAD3 SMAD family member 3
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SPTSSB serine palmitoyltransferase, small subunit B
SRI sorcin
SSTR1 somatostatin receptor 1
TBXAS1 thromboxane A synthase 1 (platelet)
TFAP2E transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon)
TINAG tubulointerstitial nephritis antigen
TM9SF3 transmembrane 9 superfamily member 3
TMCO4 transmembrane and coiled-coil domains 4
TMEM141 transmembrane protein 141
TMEM196 transmembrane protein 196
TMEM218 transmembrane protein 218
TMPRSS4 transmembrane protease, serine 4
TNF tumor necrosis factor
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TRIM42 tripartite motif containing 42
TRIO trio Rho guanine nucleotide exchange factor
TRMT1 tRNA methyltransferase 1 homolog (S. cerevisiae)
VRK3 vaccinia related kinase 3
WNT2B wingless-type MMTV integration site family, member 2B
XCL2 chemokine (C motif) ligand 2
YIPF1 Yip1 domain family, member 1
ZCCHC8 zinc finger, CCHC domain containing 8
ZNF222 zinc finger protein 222
ZNF713 zinc finger protein 713