NFATC2 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2|This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Apr 2012] (NCBI Entrez Gene Database, 4773)
External Link https://ncbi.nlm.nih.gov/gene/4773
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Genes

498 genes differentially expressed following the NFATC2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
RPS4Y1 ribosomal protein S4, Y-linked 1 0.021734
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.0216933
IFITM1 interferon induced transmembrane protein 1 0.0180741
KDM5D lysine (K)-specific demethylase 5D 0.0166395
LTF lactotransferrin 0.0160785
ARID4A AT rich interactive domain 4A (RBP1-like) 0.0159685
CFI complement factor I 0.0155216
HBB hemoglobin, beta 0.0150276
LCN2 lipocalin 2 0.0144807
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 0.0143207
CXCL8 chemokine (C-X-C motif) ligand 8 0.0142194
CDH3 cadherin 3, type 1, P-cadherin (placental) 0.0139255
S100A9 S100 calcium binding protein A9 0.0138678
LXN latexin 0.0137484
CSTA cystatin A (stefin A) 0.0135704
SLPI secretory leukocyte peptidase inhibitor 0.0135035
LGALS13 lectin, galactoside-binding, soluble, 13 0.0132421
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.0129075
IFITM2 interferon induced transmembrane protein 2 0.0124365
FABP7 fatty acid binding protein 7, brain 0.0123383
PITX3 paired-like homeodomain 3 0.0122563
IFITM3 interferon induced transmembrane protein 3 0.0118201
PRDX2 peroxiredoxin 2 0.0117641
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 0.011655
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.0114901
MGP matrix Gla protein 0.0114835
WFDC2 WAP four-disulfide core domain 2 0.0114463
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.0113697
LPAR6 lysophosphatidic acid receptor 6 0.0110943
GCA grancalcin, EF-hand calcium binding protein 0.0110235
MAL mal, T-cell differentiation protein 0.0110055
MSMO1 methylsterol monooxygenase 1 0.0109374
BEX1 brain expressed, X-linked 1 0.0108993
METTL7A methyltransferase like 7A 0.0108789
KRT13 keratin 13, type I 0.0108143
PLAT plasminogen activator, tissue 0.0107206
AK4 adenylate kinase 4 0.0106753
NR2F2 nuclear receptor subfamily 2, group F, member 2 0.0106404
MNDA myeloid cell nuclear differentiation antigen 0.0106305
LY86 lymphocyte antigen 86 0.010609
LRRC17 leucine rich repeat containing 17 0.010559
GPM6B glycoprotein M6B 0.0105326
CETN2 centrin, EF-hand protein, 2 0.0105294
C7 complement component 7 0.0105121
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 0.0104293
SELL selectin L 0.0103725
CD48 CD48 molecule 0.0102653
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 0.0101928
DCK deoxycytidine kinase 0.0101537
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 0.0101301
CCL20 chemokine (C-C motif) ligand 20 0.00986421
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.00984355
PADI2 peptidyl arginine deiminase, type II 0.00984057
FXYD6 FXYD domain containing ion transport regulator 6 0.00983424
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.00979808
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.00978019
LST1 leukocyte specific transcript 1 0.00975027
ANXA6 annexin A6 0.00974246
DIRAS3 DIRAS family, GTP-binding RAS-like 3 0.00969807
ANXA1 annexin A1 0.0096542
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 0.00963643
CPVL carboxypeptidase, vitellogenic-like 0.00962379
DHRS9 dehydrogenase/reductase (SDR family) member 9 0.00957473
PEG3 paternally expressed 3 0.00955373
TSPAN6 tetraspanin 6 0.00953604
FXYD3 FXYD domain containing ion transport regulator 3 0.00952271
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00951847
CDCA4 cell division cycle associated 4 0.00947367
CLEC11A C-type lectin domain family 11, member A 0.00943966
RPL26L1 ribosomal protein L26-like 1 0.00943037
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.00941567
MDK midkine (neurite growth-promoting factor 2) 0.00940993
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) 0.00940899
FCN1 ficolin (collagen/fibrinogen domain containing) 1 0.00939957
PI3 peptidase inhibitor 3, skin-derived 0.00928219
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 0.00927982
SEPP1 selenoprotein P, plasma, 1 0.00926582
DOK5 docking protein 5 0.00925878
PRKCB protein kinase C, beta 0.00923855
C1ORF54 chromosome 1 open reading frame 54 0.00920117
CCNA1 cyclin A1 0.00919168
SRGN serglycin 0.0091551
TXNDC9 thioredoxin domain containing 9 0.00914364
NSG1 neuron specific gene family member 1 0.00911567
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.00910212
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 0.00909785
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.00907184
S100A8 S100 calcium binding protein A8 0.00904117
IDI1 isopentenyl-diphosphate delta isomerase 1 0.00902917
MAGT1 magnesium transporter 1 0.0089992
CCNA2 cyclin A2 0.00896209
IFI44L interferon-induced protein 44-like 0.00895918
GPR65 G protein-coupled receptor 65 0.00893174
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 0.00892768
ADORA2B adenosine A2b receptor 0.00892665
RGS4 regulator of G-protein signaling 4 0.00892133
RGS10 regulator of G-protein signaling 10 0.00891829
ARL3 ADP-ribosylation factor-like 3 0.0089109
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) 0.00890911
LAPTM5 lysosomal protein transmembrane 5 0.00890533
RNF144A ring finger protein 144A 0.00889514
C3 complement component 3 0.00889088
CTSH cathepsin H 0.00888527
SNX10 sorting nexin 10 0.00887342
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 0.00886527
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.00884117
ASNSD1 asparagine synthetase domain containing 1 0.00875448
DLK1 delta-like 1 homolog (Drosophila) 0.00874752
GYPC glycophorin C (Gerbich blood group) 0.00874033
NDN necdin, melanoma antigen (MAGE) family member 0.00872484
IFT52 intraflagellar transport 52 0.0087051
IFI16 interferon, gamma-inducible protein 16 0.00870439
TRIB2 tribbles pseudokinase 2 0.00862227
S100B S100 calcium binding protein B 0.00862103
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 0.00858824
IGFBP5 insulin-like growth factor binding protein 5 0.008578
PXMP2 peroxisomal membrane protein 2, 22kDa 0.00856056
ANXA3 annexin A3 0.00855561
TSPAN31 tetraspanin 31 0.0085537
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.00852972
CDC42 cell division cycle 42 0.00850311
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide 0.00850127
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.00849335
TMEM38B transmembrane protein 38B 0.00842201
ZBED8 zinc finger, BED-type containing 8 0.00838939
OLFM4 olfactomedin 4 0.00836876
GSTO1 glutathione S-transferase omega 1 0.00834607
CHEK2 checkpoint kinase 2 0.00834285
PLN phospholamban 0.00833779
CHRDL1 chordin-like 1 0.00832752
CCNG1 cyclin G1 0.00832491
TCEAL2 transcription elongation factor A (SII)-like 2 0.00831631
GPX1 glutathione peroxidase 1 0.00830566
SRPX2 sushi-repeat containing protein, X-linked 2 0.00827271
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 0.00820746
TMEM14B transmembrane protein 14B 0.0081567
SKP1 S-phase kinase-associated protein 1 0.0081413
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 0.00813193
AQP9 aquaporin 9 0.00810872
JPT1 Jupiter microtubule associated homolog 1 0.00810039
FRZB frizzled-related protein 0.00809237
TYROBP TYRO protein tyrosine kinase binding protein 0.00808953
ALOX5 arachidonate 5-lipoxygenase 0.00806724
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G 0.00806418
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.00805625
NME4 NME/NM23 nucleoside diphosphate kinase 4 0.00805562
KCTD12 potassium channel tetramerization domain containing 12 0.00801318
PNMA2 paraneoplastic Ma antigen 2 0.00800699
LIPT1 lipoyltransferase 1 0.0079701
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.00795713
DCXR dicarbonyl/L-xylulose reductase 0.00791923
LTBP1 latent transforming growth factor beta binding protein 1 0.00790142
DEFB1 defensin, beta 1 0.00788393
ERLIN2 ER lipid raft associated 2 0.00788095
TMEM255A transmembrane protein 255A 0.00787993
MRPS33 mitochondrial ribosomal protein S33 0.00787231
GINS2 GINS complex subunit 2 (Psf2 homolog) 0.00787026
AIF1 allograft inflammatory factor 1 0.00779796
IL33 interleukin 33 0.00779693
NPTX2 neuronal pentraxin II 0.0077963
CD300A CD300a molecule 0.00779369
FAM107A family with sequence similarity 107, member A 0.00777989
CASP1 caspase 1, apoptosis-related cysteine peptidase 0.0077701
NIPSNAP2 nipsnap homolog 2 0.00774447
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.00774381
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.00773971
KRCC1 lysine-rich coiled-coil 1 0.00773881
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 0.00769497
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 0.00769234
OLFML3 olfactomedin-like 3 0.00768721
WWTR1 WW domain containing transcription regulator 1 0.00767059
STOM stomatin 0.00765306
BAMBI BMP and activin membrane-bound inhibitor 0.00763028
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.00761296
PTN pleiotrophin 0.00760644
TSNAX translin-associated factor X 0.00752731
MRS2 MRS2 magnesium transporter 0.00752413
THYN1 thymocyte nuclear protein 1 0.00751586
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 0.00749699
PMP2 peripheral myelin protein 2 0.00749289
RPA3 replication protein A3, 14kDa 0.00748823
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 0.00748646
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 0.00748639
COX7B cytochrome c oxidase subunit VIIb 0.00747681
CXCL12 chemokine (C-X-C motif) ligand 12 0.00745608
PCLAF PCNA clamp associated factor 0.00745123
HSDL2 hydroxysteroid dehydrogenase like 2 0.0074501
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A 0.00744553
NREP neuronal regeneration related protein 0.00743225
BPIFA1 BPI fold containing family A, member 1 0.00742149
CLIC5 chloride intracellular channel 5 0.00741531
CCL4 chemokine (C-C motif) ligand 4 0.00741397
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.00740702
LTA4H leukotriene A4 hydrolase 0.00740069
S100A12 S100 calcium binding protein A12 0.00739221
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 0.00738768
KRT19 keratin 19, type I 0.00737506
ACAT2 acetyl-CoA acetyltransferase 2 0.00736589
MSLN mesothelin 0.00735311
CD53 CD53 molecule 0.00734605
STEAP1 six transmembrane epithelial antigen of the prostate 1 0.00732652
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) 0.00731246
EAPP E2F-associated phosphoprotein 0.00730178
TCF21 transcription factor 21 0.0072965
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) 0.00729548
TRMT5 tRNA methyltransferase 5 0.00728838
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.00728836
CGRRF1 cell growth regulator with ring finger domain 1 0.0072867
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 0.00727814
PEX2 peroxisomal biogenesis factor 2 0.00725609
RHOT1 ras homolog family member T1 0.00725045
RLN1 relaxin 1 0.00724515
KLRB1 killer cell lectin-like receptor subfamily B, member 1 0.00723517
B3GNT1 0.00723403
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 0.00723134
TACSTD2 tumor-associated calcium signal transducer 2 0.00721818
SORD sorbitol dehydrogenase 0.00721151
S100P S100 calcium binding protein P 0.00720084
RPL36 ribosomal protein L36 0.00718339
ASCL1 achaete-scute family bHLH transcription factor 1 0.00718249
SPON1 spondin 1, extracellular matrix protein 0.00717735
PLP1 proteolipid protein 1 0.00716815
GMFG glia maturation factor, gamma 0.00716518
GEMIN2 gem (nuclear organelle) associated protein 2 0.00715694
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 0.00714625
LDB2 LIM domain binding 2 0.00711867
NSL1 NSL1, MIS12 kinetochore complex component 0.00710814
RNASE6 ribonuclease, RNase A family, k6 0.0071056
ALOX5AP arachidonate 5-lipoxygenase-activating protein 0.00709499
FPR1 formyl peptide receptor 1 0.00708798
ITM2C integral membrane protein 2C 0.00707745
MYO1C myosin IC 0.00707271
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.00707156
ICAM2 intercellular adhesion molecule 2 0.00701962
PITX1 paired-like homeodomain 1 0.00700658
MUC4 mucin 4, cell surface associated 0.00699257
INSIG1 insulin induced gene 1 0.00697257
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.00696743
IFI44 interferon-induced protein 44 0.0069491
CFB complement factor B 0.00693898
EVI2A ecotropic viral integration site 2A 0.00693664
TADA2A transcriptional adaptor 2A 0.00693334
WDR61 WD repeat domain 61 0.00692877
VRK1 vaccinia related kinase 1 0.00692301
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 0.00691372
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma 0.00691186
LYPD1 LY6/PLAUR domain containing 1 0.00690827
LSM1 LSM1, U6 small nuclear RNA associated 0.00690701
CYBB cytochrome b-245, beta polypeptide 0.00690397
TSPAN7 tetraspanin 7 0.0069014

decreased expression

Symbol Name Standardized Value
MAP7 microtubule-associated protein 7 -0.0316213
XIC X chromosome inactivation center -0.0225524
SLC38A1 solute carrier family 38, member 1 -0.0163969
MAGEA3 melanoma antigen family A3 -0.0152876
SPRED2 sprouty-related, EVH1 domain containing 2 -0.0151578
AMIGO2 adhesion molecule with Ig-like domain 2 -0.0147624
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) -0.0145365
SCGB2A2 secretoglobin, family 2A, member 2 -0.0141622
SSBP2 single-stranded DNA binding protein 2 -0.0134014
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.0132901
PERP PERP, TP53 apoptosis effector -0.0132538
SCGB1D2 secretoglobin, family 1D, member 2 -0.0130081
PLAAT3 phospholipase A and acyltransferase 3 -0.0128006
MTCL1 microtubule crosslinking factor 1 -0.0126825
GOLGA8A golgin A8 family, member A -0.0126652
DOCK9 dedicator of cytokinesis 9 -0.0124365
SLC39A14 solute carrier family 39 (zinc transporter), member 14 -0.0118153
PMP22 peripheral myelin protein 22 -0.0118025
RGS13 regulator of G-protein signaling 13 -0.0115943
AMDHD2 amidohydrolase domain containing 2 -0.011553
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked -0.0115395
CTSA cathepsin A -0.0112963
SGK1 serum/glucocorticoid regulated kinase 1 -0.0111688
TUFT1 tuftelin 1 -0.0111321
CXCL9 chemokine (C-X-C motif) ligand 9 -0.010867
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 -0.0106962
KRT7 keratin 7, type II -0.0105778
EPB41L4B erythrocyte membrane protein band 4.1 like 4B -0.0104636
TENT4A terminal nucleotidyltransferase 4A -0.0103833
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) -0.0103785
GPNMB glycoprotein (transmembrane) nmb -0.0102762
DYNLL1 dynein, light chain, LC8-type 1 -0.00997542
DDAH1 dimethylarginine dimethylaminohydrolase 1 -0.009906
RBPMS RNA binding protein with multiple splicing -0.00989079
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 -0.0098464
RFTN1 raftlin, lipid raft linker 1 -0.00976192
SQSTM1 sequestosome 1 -0.00975115
NAV2 neuron navigator 2 -0.00972887
PLXNB2 plexin B2 -0.00958322
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 -0.009521
CD40 CD40 molecule, TNF receptor superfamily member 5 -0.00947339
PXDC1 PX domain containing 1 -0.00939421
SLCO4A1 solute carrier organic anion transporter family, member 4A1 -0.00936931
SIK1 salt-inducible kinase 1 -0.00935989
IRS1 insulin receptor substrate 1 -0.00915207
PLXND1 plexin D1 -0.00907876
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 -0.00897296
PDE10A phosphodiesterase 10A -0.00896547
ITSN2 intersectin 2 -0.00893699
HIST1H2BK histone cluster 1, H2bk -0.00883236
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 -0.00881269
MYO6 myosin VI -0.00879221
MGLL monoglyceride lipase -0.00875017
PILRB paired immunoglobin-like type 2 receptor beta -0.0087416
TBX3 T-box 3 -0.00873378
TRIB3 tribbles pseudokinase 3 -0.00872421
ACADVL acyl-CoA dehydrogenase, very long chain -0.00869421
LUM lumican -0.0086888
DUSP5 dual specificity phosphatase 5 -0.00867414
COMP cartilage oligomeric matrix protein -0.00861228
MVP major vault protein -0.00855534
CLU clusterin -0.00855445
HMOX1 heme oxygenase 1 -0.00854995
CCN3 cellular communication network factor 3 -0.00854341
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 -0.0085427
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -0.00852749
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 -0.00849822
COL15A1 collagen, type XV, alpha 1 -0.00849802
QPCT glutaminyl-peptide cyclotransferase -0.00849535
TES testin LIM domain protein -0.00848748
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 -0.00848132
SWAP70 SWAP switching B-cell complex 70kDa subunit -0.0084758
SDC4 syndecan 4 -0.00847048
IGF2R insulin-like growth factor 2 receptor -0.00839847
IGSF3 immunoglobulin superfamily, member 3 -0.00838044
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) -0.00837137
GOLIM4 golgi integral membrane protein 4 -0.00836115
GNG11 guanine nucleotide binding protein (G protein), gamma 11 -0.00835508
PKD1P1 polycystic kidney disease 1 (autosomal dominant) pseudogene 1 -0.00832118
PLXNA1 plexin A1 -0.00821859
COL7A1 collagen, type VII, alpha 1 -0.00815413
FAM13A family with sequence similarity 13, member A -0.00813806
ACTN4 actinin, alpha 4 -0.00812111
TOX3 TOX high mobility group box family member 3 -0.00810007
RABEP2 rabaptin, RAB GTPase binding effector protein 2 -0.00809781
KRT16 keratin 16, type I -0.00804414
TRIB1 tribbles pseudokinase 1 -0.00804398
RGS16 regulator of G-protein signaling 16 -0.00799136
CLCN7 chloride channel, voltage-sensitive 7 -0.00797727
DST dystonin -0.00795285
PIEZO1 piezo-type mechanosensitive ion channel component 1 -0.00795262
NBPF10 neuroblastoma breakpoint family, member 10 -0.0079427
UBA1 ubiquitin-like modifier activating enzyme 1 -0.00793817
AP3D1 adaptor-related protein complex 3, delta 1 subunit -0.0079184
CDK5RAP3 CDK5 regulatory subunit associated protein 3 -0.007906
STK25 serine/threonine kinase 25 -0.00789849
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1 -0.00787075
NAXD NAD(P)HX dehydratase -0.00785718
PNN pinin, desmosome associated protein -0.00785317
MARCHF6 membrane associated ring-CH-type finger 6 -0.00781267
AKAP8L A kinase (PRKA) anchor protein 8-like -0.00780638
EZR ezrin -0.00778763
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.00777434
HGS hepatocyte growth factor-regulated tyrosine kinase substrate -0.0077644
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.00772964
INPPL1 inositol polyphosphate phosphatase-like 1 -0.00772312
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -0.00771038
MIR22HG MIR22 host gene -0.00768939
MMP3 matrix metallopeptidase 3 -0.00768544
ECM1 extracellular matrix protein 1 -0.00765034
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 -0.00764523
GREM1 gremlin 1, DAN family BMP antagonist -0.00764507
CCNL2 cyclin L2 -0.00761731
HIST1H2BD histone cluster 1, H2bd -0.00760014
FAM50A family with sequence similarity 50, member A -0.00759187
CDC34 cell division cycle 34 -0.00758493
EIF3B eukaryotic translation initiation factor 3, subunit B -0.00754089
MET MET proto-oncogene, receptor tyrosine kinase -0.00753562
MMP2 matrix metallopeptidase 2 -0.00751023
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase -0.00742843
KLF4 Kruppel-like factor 4 (gut) -0.00742481
ZEB1 zinc finger E-box binding homeobox 1 -0.00738596
RUBCN rubicon autophagy regulator -0.00735398
BRD4 bromodomain containing 4 -0.00729992
DKK1 dickkopf WNT signaling pathway inhibitor 1 -0.00729823
CCDC86 coiled-coil domain containing 86 -0.00729625
ULK1 unc-51 like autophagy activating kinase 1 -0.00728388
MID1 midline 1 -0.00726778
ZNF638 zinc finger protein 638 -0.00724058
INPP5A inositol polyphosphate-5-phosphatase, 40kDa -0.00723717
MAGEA12 melanoma antigen family A12 -0.00723297
MITF microphthalmia-associated transcription factor -0.00719977
BTBD3 BTB (POZ) domain containing 3 -0.00719742
SBF1 SET binding factor 1 -0.00719675
IER5 immediate early response 5 -0.00719197
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 -0.0071745
PSD3 pleckstrin and Sec7 domain containing 3 -0.00715568
TPSAB1 tryptase alpha/beta 1 -0.00714529
KANK1 KN motif and ankyrin repeat domains 1 -0.00714513
CYB5R2 cytochrome b5 reductase 2 -0.00714253
RND3 Rho family GTPase 3 -0.00711485
TGFBI transforming growth factor, beta-induced, 68kDa -0.00709933
CLUH clustered mitochondria (cluA/CLU1) homolog -0.00707123
HSPA1A heat shock 70kDa protein 1A -0.00706175
PHACTR2 phosphatase and actin regulator 2 -0.007052
RPL10 ribosomal protein L10 -0.00704772
FAM160B2 family with sequence similarity 160, member B2 -0.00703345
DVL1 dishevelled segment polarity protein 1 -0.0070324
MBD1 methyl-CpG binding domain protein 1 -0.0070314
PRSS3 protease, serine, 3 -0.00699645
OFD1 oral-facial-digital syndrome 1 -0.00698425
SETD5 SET domain containing 5 -0.00695735
NOP2 NOP2 nucleolar protein -0.00695413
CDR2L cerebellar degeneration-related protein 2-like -0.00694698
MAN2A1 mannosidase, alpha, class 2A, member 1 -0.00693418
PEG10 paternally expressed 10 -0.00692739
NNMT nicotinamide N-methyltransferase -0.00691608
DMPK dystrophia myotonica-protein kinase -0.00690768
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) -0.00689272
EXT1 exostosin glycosyltransferase 1 -0.0068811
LONP1 lon peptidase 1, mitochondrial -0.00685562
HIP1R huntingtin interacting protein 1 related -0.00685545
NPIPA1 nuclear pore complex interacting protein family, member A1 -0.00685223
PON3 paraoxonase 3 -0.00683891
TPCN1 two pore segment channel 1 -0.00683715
SOX9 SRY (sex determining region Y)-box 9 -0.0068344
DCLK1 doublecortin-like kinase 1 -0.00682285
LYPD3 LY6/PLAUR domain containing 3 -0.00680234
MAEA macrophage erythroblast attacher -0.0068004
TESK1 testis-specific kinase 1 -0.00678688
CHD4 chromodomain helicase DNA binding protein 4 -0.00674916
ITGAV integrin, alpha V -0.00674334
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) -0.00673704
C8ORF4 chromosome 8 open reading frame 4 -0.0067366
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) -0.00668293
MEST mesoderm specific transcript -0.0066747
BASP1 brain abundant, membrane attached signal protein 1 -0.00667325
ENAH enabled homolog (Drosophila) -0.00665868
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -0.00665758
MYC v-myc avian myelocytomatosis viral oncogene homolog -0.00665573
MTUS1 microtubule associated tumor suppressor 1 -0.00665485
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit -0.00665431
GULP1 GULP, engulfment adaptor PTB domain containing 1 -0.00664544
NOTCH2NL notch 2 N-terminal like -0.00662606
CARD10 caspase recruitment domain family, member 10 -0.00661419
TXLNA taxilin alpha -0.00658766
EIF6 eukaryotic translation initiation factor 6 -0.00657944
FTH1 ferritin, heavy polypeptide 1 -0.00657752
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 -0.00657717
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase -0.00655655
ZNF83 zinc finger protein 83 -0.00655196
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -0.0065497
ZNF395 zinc finger protein 395 -0.00654072
INHBB inhibin, beta B -0.00653469
INA internexin neuronal intermediate filament protein, alpha -0.00653382
GLS glutaminase -0.00653179
PWP2 PWP2 periodic tryptophan protein homolog (yeast) -0.00652399
NPC1 Niemann-Pick disease, type C1 -0.00652117
DGKZ diacylglycerol kinase, zeta -0.00651771
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 -0.00651148
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) -0.0065066
ATG4B autophagy related 4B, cysteine peptidase -0.00650094
COL4A2 collagen, type IV, alpha 2 -0.006478
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 -0.00647543
SH3GLB2 SH3-domain GRB2-like endophilin B2 -0.00645931
FHL2 four and a half LIM domains 2 -0.00643541
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) -0.00641532
TNK2 tyrosine kinase, non-receptor, 2 -0.00641319
GOLGB1 golgin B1 -0.0063996
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2 -0.00639216
CPB1 carboxypeptidase B1 (tissue) -0.00638253
PAX5 paired box 5 -0.00637713
OSBPL10 oxysterol binding protein-like 10 -0.00637278
FADS3 fatty acid desaturase 3 -0.00637212
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 -0.00636567
ATP13A1 ATPase type 13A1 -0.00636323
RANGAP1 Ran GTPase activating protein 1 -0.00634329
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit -0.00634106
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 -0.00633119
BTF3P11 basic transcription factor 3 pseudogene 11 -0.00632307
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -0.00631877
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 -0.00630903
SFI1 Sfi1 homolog, spindle assembly associated (yeast) -0.00630701
GAREM1 GRB2 associated regulator of MAPK1 subtype 1 -0.00630257
BCAP31 B-cell receptor-associated protein 31 -0.0063007
GGT1 gamma-glutamyltransferase 1 -0.00629383
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 -0.00628752
EPS8L2 EPS8-like 2 -0.00628518
DPP4 dipeptidyl-peptidase 4 -0.00626989
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 -0.00626956
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1 -0.00626872
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent) -0.00626288
ZDHHC11 zinc finger, DHHC-type containing 11 -0.00626205
TIMP1 TIMP metallopeptidase inhibitor 1 -0.00626134
PRKCSH protein kinase C substrate 80K-H -0.00625975
DMTF1 cyclin D binding myb-like transcription factor 1 -0.0062583
MED15 mediator complex subunit 15 -0.00625698
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1 -0.00625024
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 -0.00623861
TGFB1 transforming growth factor, beta 1 -0.00623747
GLA galactosidase, alpha -0.00623387
TRIO trio Rho guanine nucleotide exchange factor -0.00622814
CGA glycoprotein hormones, alpha polypeptide -0.00622807
POSTN periostin, osteoblast specific factor -0.00622368
BAZ2A bromodomain adjacent to zinc finger domain, 2A -0.00622033
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3 -0.0062197
PHLDA2 pleckstrin homology-like domain, family A, member 2 -0.00621888
FRY furry homolog (Drosophila) -0.00621186