NFE2 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description nuclear factor, erythroid 2| (NCBI Entrez Gene Database, 4778)
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Genes

288 genes differentially expressed following the NFE2 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
PCDHGA1 protocadherin gamma subfamily A, 1 3.27948
KLF2 Kruppel-like factor 2 3.27948
VIT vitrin 3.27948
PTPN7 protein tyrosine phosphatase, non-receptor type 7 3.27948
DMTN dematin actin binding protein 3.27948
ASPG asparaginase 3.27948
FCMR Fc fragment of IgM receptor 3.27948
DAND5 DAN domain family member 5, BMP antagonist 3.27948
C11ORF16 chromosome 11 open reading frame 16 3.27948
CCNB3 cyclin B3 3.27948
AGXT2 alanine--glyoxylate aminotransferase 2 3.27948
PRB2 proline-rich protein BstNI subfamily 2 3.27948
NLRP3 NLR family, pyrin domain containing 3 3.27948
NUTM2D NUT family member 2D 3.27948
OVGP1 oviductal glycoprotein 1, 120kDa 3.27948
GCSAML germinal center-associated, signaling and motility-like 3.27948
OTP orthopedia homeobox 3.27948
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 3.27948
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal) 3.27948
OR10A4 olfactory receptor, family 10, subfamily A, member 4 3.27157
UCN urocortin 3.27157
UPB1 ureidopropionase, beta 3.27157
AKR7L aldo-keto reductase family 7-like (gene/pseudogene) 3.27157
OR2B6 olfactory receptor, family 2, subfamily B, member 6 3.27157
SOX18 SRY (sex determining region Y)-box 18 3.27157
VWA5B2 von Willebrand factor A domain containing 5B2 3.27157
ZNF492 zinc finger protein 492 3.27157
ZNF467 zinc finger protein 467 3.27157
RAX retina and anterior neural fold homeobox 3.27157
SPINK6 serine peptidase inhibitor, Kazal type 6 3.27157
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B 3.27157
SLC39A5 solute carrier family 39 (zinc transporter), member 5 3.27157
GJB1 gap junction protein, beta 1, 32kDa 3.27157
SLC22A6 solute carrier family 22 (organic anion transporter), member 6 3.27157
KCNU1 potassium channel, subfamily U, member 1 3.27157
THEMIS thymocyte selection associated 3.27157
MYO1G myosin IG 3.27157
LGALS8 lectin, galactoside-binding, soluble, 8 3.27157
MMP20 matrix metallopeptidase 20 3.27157
CRIP1 cysteine-rich protein 1 (intestinal) 3.27157
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5 3.27157
ASMT acetylserotonin O-methyltransferase 3.27157
BIRC3 baculoviral IAP repeat containing 3 3.27157
GFI1 growth factor independent 1 transcription repressor 3.27157
ESPN espin 3.27157
GABRA6 gamma-aminobutyric acid (GABA) A receptor, alpha 6 3.27157
PAX5 paired box 5 3.27157
CRYAA crystallin, alpha A 3.27157
FFAR4 free fatty acid receptor 4 3.27157
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides 3.27157
DHRS9 dehydrogenase/reductase (SDR family) member 9 3.27157
NAPSA napsin A aspartic peptidase 3.27157
CIROZ ciliated left-right organizer protein containing ZP-N domains 3.27157
KY kyphoscoliosis peptidase 3.27157
LTB4R2 leukotriene B4 receptor 2 3.27157
CCER2 coiled-coil glutamate-rich protein 2 3.27157
PNLIPRP1 pancreatic lipase-related protein 1 3.27157
MGAT4D MGAT4 family, member D 3.27157
SPI1 Spi-1 proto-oncogene 3.27157
SPRR2A small proline-rich protein 2A 3.27157
SMLR1 small leucine-rich protein 1 3.27157
IRAG2 inositol 1,4,5-triphosphate receptor associated 2 3.27157
VSIR V-set immunoregulatory receptor 3.27157
PRR20G proline rich 20G 3.27157
LY6S-AS1 LY6S antisense RNA 1 3.27157
OR52P1 olfactory receptor family 52 subfamily P member 1 (gene/pseudogene) 3.27157
MINDY4B MINDY family member 4B 3.27157
TEX13D TEX13 family member D 3.27157
ANKRD40CL ANKRD40 C-terminal like 3.27157
GUCY1A1 guanylate cyclase 1 soluble subunit alpha 1 3.27157
TMEM275 transmembrane protein 275 3.27157
APOBEC3H apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H 3.27157
SPATA22 spermatogenesis associated 22 3.27157
GPR37L1 G protein-coupled receptor 37 like 1 3.27157
NR1I3 nuclear receptor subfamily 1, group I, member 3 3.27157
IL31RA interleukin 31 receptor A 3.27157
TRIM60 tripartite motif containing 60 3.27157
CCDC17 coiled-coil domain containing 17 3.27157
RS1 retinoschisin 1 3.27157
PVRIG poliovirus receptor related immunoglobulin domain containing 3.27157
SYCP2 synaptonemal complex protein 2 3.27157
CST11 cystatin 11 3.27157
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit 3.27157
MEX3A mex-3 RNA binding family member A 3.27157
ARMCX5-GPRASP2 ARMCX5-GPRASP2 readthrough 3.27157
TBX10 T-box 10 3.27157
GPR85 G protein-coupled receptor 85 3.27157
FMR1NB fragile X mental retardation 1 neighbor 3.27157
TSPO2 translocator protein 2 3.27157
KCNT1 potassium channel, sodium activated subfamily T, member 1 3.27157
KLRF1 killer cell lectin-like receptor subfamily F, member 1 3.27157
SLAMF9 SLAM family member 9 3.27157
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime 3.27157
CD22 CD22 molecule 3.27157
TESPA1 thymocyte expressed, positive selection associated 1 3.27157
PAGE4 P antigen family, member 4 (prostate associated) 3.27157
HPX hemopexin 3.27157
TBC1D10C TBC1 domain family, member 10C 3.27157
CAMK2B calcium/calmodulin-dependent protein kinase II beta 3.27157
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 3.27157
ARR3 arrestin 3, retinal (X-arrestin) 3.27157
BTNL8 butyrophilin-like 8 3.27157
DEFB135 defensin, beta 135 3.27157
OTC ornithine carbamoyltransferase 3.27157
UBQLNL ubiquilin-like 3.27157
HCRT hypocretin (orexin) neuropeptide precursor 3.27157
NIM1K NIM1 serine/threonine protein kinase 3.27157
AKR1B15 aldo-keto reductase family 1, member B15 3.27157
KCNK4 potassium channel, two pore domain subfamily K, member 4 3.27157
LRRC46 leucine rich repeat containing 46 3.27157
KCNS2 potassium voltage-gated channel, modifier subfamily S, member 2 3.27157
CABP7 calcium binding protein 7 3.27157
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 3.27157
ASB4 ankyrin repeat and SOCS box containing 4 3.27157
FBXO47 F-box protein 47 3.27157
OR52N1 olfactory receptor, family 52, subfamily N, member 1 3.27157
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 3.27157
EOMES eomesodermin 3.27157
PLA2G5 phospholipase A2, group V 3.27157
WNT10A wingless-type MMTV integration site family, member 10A 3.27157
CAPSL calcyphosine-like 3.27157
LRRC25 leucine rich repeat containing 25 3.27157
BCL2L15 BCL2-like 15 3.27157
NCR3 natural cytotoxicity triggering receptor 3 3.27157
HIGD2B HIG1 hypoxia inducible domain family, member 2B 3.27157
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled 3.27157
TPPP2 tubulin polymerization-promoting protein family member 2 3.27157
TG thyroglobulin 3.27157
PRR35 proline rich 35 3.27157
SVOP SV2 related protein homolog (rat) 3.27157
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 3.27157
EGR2 early growth response 2 3.27157
SMIM22 small integral membrane protein 22 3.27157
FZD1 frizzled class receptor 1 3.27157
ERP27 endoplasmic reticulum protein 27 3.27157
PPP1R3G protein phosphatase 1, regulatory subunit 3G 3.27157
OR14A2 olfactory receptor, family 14, subfamily A, member 2 3.27157
DKK2 dickkopf WNT signaling pathway inhibitor 2 3.27157
XCR1 chemokine (C motif) receptor 1 3.27157
IFNE interferon, epsilon 3.27157
CLEC2B C-type lectin domain family 2, member B 3.27157
MKS1 Meckel syndrome, type 1 3.27157
CHRDL2 chordin-like 2 3.27157
NPC1L1 NPC1-like 1 3.27157
KIF4B kinesin family member 4B 3.27157
NKPD1 NTPase, KAP family P-loop domain containing 1 3.27157
SLITRK6 SLIT and NTRK-like family, member 6 3.27157
DUOXA1 dual oxidase maturation factor 1 3.27157
GPRC5D G protein-coupled receptor, class C, group 5, member D 3.27157
ANGPTL2 angiopoietin-like 2 3.27157
RCC2 regulator of chromosome condensation 2 3.26878
SLC24A4 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 3.24891
OR2AG2 olfactory receptor, family 2, subfamily AG, member 2 3.24891
ZNF106 zinc finger protein 106 3.23379
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 3.23358
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 3.19147
COL17A1 collagen, type XVII, alpha 1 2.90423
NOX3 NADPH oxidase 3 2.75252
PROSER3 proline and serine rich 3 2.66204
CNTROB centrobin, centrosomal BRCA2 interacting protein 2.64545
MTCH2 mitochondrial carrier 2 2.60507
RBM19 RNA binding motif protein 19 2.51209
PAXBP1 PAX3 and PAX7 binding protein 1 2.50426
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 2.41437
NME5 NME/NM23 family member 5 2.39847
AMZ1 archaelysin family metallopeptidase 1 2.39716
ATP5MG ATP synthase membrane subunit g 2.39386
NCMAP noncompact myelin associated protein 2.35351
CTNND2 catenin (cadherin-associated protein), delta 2 2.34107
IL32 interleukin 32 2.30913
ELAC1 elaC ribonuclease Z 1 2.30913
SPAG6 sperm associated antigen 6 2.30411
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma 2.28328
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 2.26671
CCDC3 coiled-coil domain containing 3 2.26566
ATG9B autophagy related 9B 2.25522
NOXA1 NADPH oxidase activator 1 2.25522
RPA4 replication protein A4, 30kDa 2.25522
PABPC1L2A poly(A) binding protein, cytoplasmic 1-like 2A 2.25522
FOSL2 FOS-like antigen 2 2.25522
IGSF22 immunoglobulin superfamily, member 22 2.25522
MYO16 myosin XVI 2.25522
DCST1 DC-STAMP domain containing 1 2.25522
SPINK13 serine peptidase inhibitor, Kazal type 13 (putative) 2.2544
ANKRD61 ankyrin repeat domain 61 2.2544
OR56A1 olfactory receptor, family 56, subfamily A, member 1 2.2544
PWWP3A PWWP domain containing 3A, DNA repair factor 2.2527
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3 2.24667
CEP55 centrosomal protein 55kDa 2.24375
SULT6B1 sulfotransferase family, cytosolic, 6B, member 1 2.23993
HUS1B HUS1 checkpoint homolog b (S. pombe) 2.23993
PRRT4 proline-rich transmembrane protein 4 2.23993
PLK3 polo-like kinase 3 2.23753
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 2.22214
ZNF578 zinc finger protein 578 2.22158
IPO7 importin 7 2.19025
LHFPL5 lipoma HMGIC fusion partner-like 5 2.18977
SYNJ2BP synaptojanin 2 binding protein 2.18831
ETFA electron-transfer-flavoprotein, alpha polypeptide 2.17731
VASH1 vasohibin 1 2.1719
AASS aminoadipate-semialdehyde synthase 2.16332
FBP2 fructose-1,6-bisphosphatase 2 2.10104
SEPTIN5 septin 5 2.10104
CCDC68 coiled-coil domain containing 68 2.10104
KHSRP KH-type splicing regulatory protein 2.06526
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle) 2.05582
GNPTG N-acetylglucosamine-1-phosphate transferase, gamma subunit 2.04544
LY75 lymphocyte antigen 75 2.04176
MRPL58 mitochondrial ribosomal protein L58 2.03109
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6 2.02161
CDR2 cerebellar degeneration-related protein 2, 62kDa 2.02114
SPINK8 serine peptidase inhibitor, Kazal type 8 (putative) 2.01449
CHPF chondroitin polymerizing factor 2.01062

decreased expression

Symbol Name Standardized Value
SLA Src-like-adaptor -3.27948
UTS2B urotensin 2B -3.27948
HORMAD2 HORMA domain containing 2 -3.27948
CFAP74 cilia and flagella associated protein 74 -3.27948
C3AR1 complement component 3a receptor 1 -3.26878
TSHZ1 teashirt zinc finger homeobox 1 -3.26878
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 -3.26878
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -3.26878
ITPKA inositol-trisphosphate 3-kinase A -3.26878
CYP4Z1 cytochrome P450, family 4, subfamily Z, polypeptide 1 -3.26878
YY2 YY2 transcription factor -3.26878
ACP4 acid phosphatase 4 -3.26878
ALPK2 alpha-kinase 2 -3.26878
DRICH1 aspartate-rich 1 -3.26878
UNC13C unc-13 homolog C (C. elegans) -3.26878
FAM153A family with sequence similarity 153, member A -3.26878
STARD6 StAR-related lipid transfer (START) domain containing 6 -3.26878
ALX4 ALX homeobox 4 -3.26878
ACTR3C ARP3 actin-related protein 3 homolog C (yeast) -3.26878
TMIGD2 transmembrane and immunoglobulin domain containing 2 -3.26878
TMED6 transmembrane emp24 protein transport domain containing 6 -3.26878
UPK1B uroplakin 1B -3.26878
NMBR neuromedin B receptor -3.26878
GOLGA6A golgin A6 family, member A -3.26878
CLEC4D C-type lectin domain family 4, member D -3.26878
NUTM2E NUT family member 2E -3.17701
METTL6 methyltransferase like 6 -3.00431
PAH phenylalanine hydroxylase -2.74975
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -2.56735
UBP1 upstream binding protein 1 (LBP-1a) -2.5095
FAM50A family with sequence similarity 50, member A -2.45353
SOX12 SRY (sex determining region Y)-box 12 -2.39655
AP2A2 adaptor-related protein complex 2, alpha 2 subunit -2.31853
PSIP1 PC4 and SFRS1 interacting protein 1 -2.26857
OSBPL9 oxysterol binding protein-like 9 -2.26566
VSTM2B V-set and transmembrane domain containing 2B -2.26566
PTAFR platelet-activating factor receptor -2.26566
KCNIP2 Kv channel interacting protein 2 -2.26566
ABHD12B abhydrolase domain containing 12B -2.26566
COG2 component of oligomeric golgi complex 2 -2.26566
RNF112 ring finger protein 112 -2.26566
FZD8 frizzled class receptor 8 -2.26566
PHLDB2 pleckstrin homology-like domain, family B, member 2 -2.26566
JMJD8 jumonji domain containing 8 -2.26448
EFNB3 ephrin-B3 -2.24401
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2 -2.23753
ZNF524 zinc finger protein 524 -2.23753
ZNF527 zinc finger protein 527 -2.22722
QRFPR pyroglutamylated RFamide peptide receptor -2.22722
GPALPP1 GPALPP motifs containing 1 -2.21365
TMEM101 transmembrane protein 101 -2.20376
GRM5 glutamate receptor, metabotropic 5 -2.19025
PCDHA6 protocadherin alpha 6 -2.18831
MLIP muscular LMNA-interacting protein -2.18831
COX17 COX17 cytochrome c oxidase copper chaperone -2.18831
ADAT3 adenosine deaminase, tRNA-specific 3 -2.18831
COLEC11 collectin sub-family member 11 -2.18831
SLC25A51 solute carrier family 25, member 51 -2.18435
ZNF768 zinc finger protein 768 -2.17684
SAP30L SAP30-like -2.17208
SEC63 SEC63 homolog (S. cerevisiae) -2.16556
NELL2 NEL-like 2 (chicken) -2.13656
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B -2.13034
FAM47E family with sequence similarity 47, member E -2.12918
PRR22 proline rich 22 -2.11192
E2F2 E2F transcription factor 2 -2.09046
TELO2 telomere maintenance 2 -2.06725
HMGA2 high mobility group AT-hook 2 -2.05142
SCAP SREBF chaperone -2.04531
MAGOHB mago-nashi homolog B (Drosophila) -2.04209
ABHD2 abhydrolase domain containing 2 -2.04176
DCLRE1B DNA cross-link repair 1B -2.04176
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -2.03547
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -2.01062
MRPL35 mitochondrial ribosomal protein L35 -2.00326