NFE2L1 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description nuclear factor, erythroid 2-like 1|This gene encodes a protein that is involved in globin gene expression in erythrocytes. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene, NFE2L1, and for "nuclear respiratory factor 1" which has an official symbol of NRF1. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 4779)
External Link https://ncbi.nlm.nih.gov/gene/4779
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Genes

499 genes differentially expressed following the NFE2L1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
SSBP2 single-stranded DNA binding protein 2 0.031537
IFI27 interferon, alpha-inducible protein 27 0.0226811
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.0195917
CXCL8 chemokine (C-X-C motif) ligand 8 0.0186955
ISG15 ISG15 ubiquitin-like modifier 0.0180067
IFI44L interferon-induced protein 44-like 0.0178153
SGK1 serum/glucocorticoid regulated kinase 1 0.0174037
MX1 MX dynamin-like GTPase 1 0.0171776
S100P S100 calcium binding protein P 0.0165842
IFI16 interferon, gamma-inducible protein 16 0.0165593
ISG20 interferon stimulated exonuclease gene 20kDa 0.0152681
MT1E metallothionein 1E 0.0151632
MVP major vault protein 0.014798
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 0.0142892
ATF3 activating transcription factor 3 0.0141632
PPP1R3C protein phosphatase 1, regulatory subunit 3C 0.0138758
LY96 lymphocyte antigen 96 0.0137374
S100A9 S100 calcium binding protein A9 0.013656
TPM4 tropomyosin 4 0.0133526
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.0133265
ABLIM1 actin binding LIM protein 1 0.0131532
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.0131354
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 0.013107
MT1HL1 metallothionein 1H-like 1 0.0130745
CRABP2 cellular retinoic acid binding protein 2 0.0124757
SP100 SP100 nuclear antigen 0.0123551
MT1F metallothionein 1F 0.0123014
MT2A metallothionein 2A 0.0122257
SPRR3 small proline-rich protein 3 0.0121595
CSTA cystatin A (stefin A) 0.0120442
NT5E 5'-nucleotidase, ecto (CD73) 0.0120412
CD59 CD59 molecule, complement regulatory protein 0.0117825
MT1G metallothionein 1G 0.0116923
DOK5 docking protein 5 0.0116475
MT1H metallothionein 1H 0.0116462
TSPAN1 tetraspanin 1 0.0116442
TCL1A T-cell leukemia/lymphoma 1A 0.0116127
PITX3 paired-like homeodomain 3 0.0115749
CLCA4 chloride channel accessory 4 0.0115704
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 0.0114928
IFI44 interferon-induced protein 44 0.0114451
PSCA prostate stem cell antigen 0.011235
MT1X metallothionein 1X 0.0111738
MX2 MX dynamin-like GTPase 2 0.0111736
LGALS4 lectin, galactoside-binding, soluble, 4 0.0111337
TM4SF1 transmembrane 4 L six family member 1 0.0111334
TRIM22 tripartite motif containing 22 0.0111294
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 0.0111007
SMAGP small cell adhesion glycoprotein 0.0110967
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 0.0110924
SPINK1 serine peptidase inhibitor, Kazal type 1 0.0110681
ACOX2 acyl-CoA oxidase 2, branched chain 0.011066
F3 coagulation factor III (thromboplastin, tissue factor) 0.0110154
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.0110031
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.0109485
FHL1 four and a half LIM domains 1 0.0109125
GPNMB glycoprotein (transmembrane) nmb 0.0108552
DEFB1 defensin, beta 1 0.0108215
HLA-B major histocompatibility complex, class I, B 0.0108188
ECM1 extracellular matrix protein 1 0.0108008
CHEK2 checkpoint kinase 2 0.0107712
LCN2 lipocalin 2 0.0107705
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 0.0107586
HNMT histamine N-methyltransferase 0.0107556
CA2 carbonic anhydrase II 0.0107389
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial 0.0106723
GLIPR1 GLI pathogenesis-related 1 0.0106342
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) 0.0105172
IFI6 interferon, alpha-inducible protein 6 0.010399
MME membrane metallo-endopeptidase 0.010395
FABP5 fatty acid binding protein 5 (psoriasis-associated) 0.0103918
CRYAB crystallin, alpha B 0.0102781
ANXA2P2 annexin A2 pseudogene 2 0.0102724
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.0102267
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 0.0102126
LYZ lysozyme 0.0102046
SP140L SP140 nuclear body protein-like 0.010079
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 0.00998931
SP110 SP110 nuclear body protein 0.00997022
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.00993826
LOX lysyl oxidase 0.00991848
RSAD2 radical S-adenosyl methionine domain containing 2 0.00985718
CXCL12 chemokine (C-X-C motif) ligand 12 0.0097706
PDZK1IP1 PDZK1 interacting protein 1 0.00976938
STX7 syntaxin 7 0.00966825
FOLR1 folate receptor 1 (adult) 0.00966496
LXN latexin 0.00959064
MXI1 MAX interactor 1, dimerization protein 0.00958461
AP1S1 adaptor-related protein complex 1, sigma 1 subunit 0.00955572
MYO1C myosin IC 0.00955133
KRT23 keratin 23, type I 0.00951931
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.00947628
LMO2 LIM domain only 2 (rhombotin-like 1) 0.00946518
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 0.00938524
CXCL14 chemokine (C-X-C motif) ligand 14 0.00937739
DRAM1 DNA-damage regulated autophagy modulator 1 0.00929811
ADM adrenomedullin 0.00927722
STAT1 signal transducer and activator of transcription 1, 91kDa 0.00926226
KRT19 keratin 19, type I 0.0092577
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) 0.00923897
BEX4 brain expressed, X-linked 4 0.009218
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 0.00917661
DUSP1 dual specificity phosphatase 1 0.00916126
PHYH phytanoyl-CoA 2-hydroxylase 0.00914549
WIPI1 WD repeat domain, phosphoinositide interacting 1 0.00913349
CRISP3 cysteine-rich secretory protein 3 0.00908895
YIPF5 Yip1 domain family, member 5 0.00907853
TPD52L1 tumor protein D52-like 1 0.00905612
MAP7 microtubule-associated protein 7 0.00904215
UBE2L6 ubiquitin-conjugating enzyme E2L 6 0.00904141
COG7 component of oligomeric golgi complex 7 0.0090384
TMEM47 transmembrane protein 47 0.00900538
TAC1 tachykinin, precursor 1 0.00897697
GNG11 guanine nucleotide binding protein (G protein), gamma 11 0.00896542
GSN gelsolin 0.00896381
HIST1H2AC histone cluster 1, H2ac 0.00896133
FXYD3 FXYD domain containing ion transport regulator 3 0.00892416
FGF1 fibroblast growth factor 1 (acidic) 0.00888538
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 0.00888377
BLNK B-cell linker 0.00886399
MAL mal, T-cell differentiation protein 0.00886319
SST somatostatin 0.00884232
XAF1 XIAP associated factor 1 0.00881227
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.00880371
OPTN optineurin 0.00877787
CTSS cathepsin S 0.0087528
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 0.00874517
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.00873391
TEX10 testis expressed 10 0.00872136
ALDOB aldolase B, fructose-bisphosphate 0.00866781
TAGLN2 transgelin 2 0.00864089
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.00863331
HSBP1 heat shock factor binding protein 1 0.00863279
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.00860372
ANXA1 annexin A1 0.00860348
AOX1 aldehyde oxidase 1 0.00857533
RGS4 regulator of G-protein signaling 4 0.00853406
RBMS1 RNA binding motif, single stranded interacting protein 1 0.00851919
GDF15 growth differentiation factor 15 0.00851857
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.00849501
EMX2 empty spiracles homeobox 2 0.00846753
LPXN leupaxin 0.00840121
LGALS3 lectin, galactoside-binding, soluble, 3 0.00833954
HLA-F major histocompatibility complex, class I, F 0.00830005
BAMBI BMP and activin membrane-bound inhibitor 0.00828785
DUOX2 dual oxidase 2 0.00826215
IL6ST interleukin 6 signal transducer 0.00825704
PLSCR4 phospholipid scramblase 4 0.0082092
S100A7 S100 calcium binding protein A7 0.00818496
PAM peptidylglycine alpha-amidating monooxygenase 0.0081673
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 0.00815563
CTSE cathepsin E 0.00814818
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 0.00814712
S100A8 S100 calcium binding protein A8 0.00814614
GPR137B G protein-coupled receptor 137B 0.00813175
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 0.00813049
FNDC3B fibronectin type III domain containing 3B 0.00812707
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.00812298
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 0.00812205
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 0.00810925
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.00810193
S100A10 S100 calcium binding protein A10 0.00806533
IFITM3 interferon induced transmembrane protein 3 0.00803027
CLDN10 claudin 10 0.00802585
NEK7 NIMA-related kinase 7 0.00802218
NRIP3 nuclear receptor interacting protein 3 0.00801668
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.00800238
AHNAK2 AHNAK nucleoprotein 2 0.00796384
ADA adenosine deaminase 0.00796229
ZDHHC6 zinc finger, DHHC-type containing 6 0.00794785
CASP4 caspase 4, apoptosis-related cysteine peptidase 0.00791832
IRF7 interferon regulatory factor 7 0.00790486
CFH complement factor H 0.00787481
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 0.00787026
F2RL1 coagulation factor II (thrombin) receptor-like 1 0.00782751
NFASC neurofascin 0.00782395
SPINK5 serine peptidase inhibitor, Kazal type 5 0.00782248
CREB3L1 cAMP responsive element binding protein 3-like 1 0.00780733
RGS1 regulator of G-protein signaling 1 0.00779141
FPGS folylpolyglutamate synthase 0.00777285
RSL1D1 ribosomal L1 domain containing 1 0.00777192
CLTB clathrin, light chain B 0.0077622
SCGB2A1 secretoglobin, family 2A, member 1 0.00774338
MCL1 myeloid cell leukemia 1 0.00773545
B2M beta-2-microglobulin 0.00768229
CAPG capping protein (actin filament), gelsolin-like 0.0076822
IFI35 interferon-induced protein 35 0.00768062
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 0.00766227
SH3BGR SH3 domain binding glutamate-rich protein 0.00765241
RND3 Rho family GTPase 3 0.00760081
DAXX death-domain associated protein 0.007587
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 0.00757575
GBP2 guanylate binding protein 2, interferon-inducible 0.00756763
CD164 CD164 molecule, sialomucin 0.00756754
AUTS2 autism susceptibility candidate 2 0.00755445
REEP5 receptor accessory protein 5 0.00755092
GNAS GNAS complex locus 0.00754366
KRT20 keratin 20, type I 0.00753035
ZMAT3 zinc finger, matrin-type 3 0.00752529
RGS10 regulator of G-protein signaling 10 0.00750609
CAST calpastatin 0.00750544
CEMIP cell migration inducing protein, hyaluronan binding 0.00749819
PHF11 PHD finger protein 11 0.00749441
HLA-C major histocompatibility complex, class I, C 0.00749081
GPX1 glutathione peroxidase 1 0.00748729
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7 0.00745563
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 0.00745071
CREM cAMP responsive element modulator 0.00742742
EPS8L1 EPS8-like 1 0.00742381
PI3 peptidase inhibitor 3, skin-derived 0.00741416
RPP40 ribonuclease P/MRP 40kDa subunit 0.00740899
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 0.00740535
NEBL nebulette 0.00740178
CDCA4 cell division cycle associated 4 0.00739038
STMN2 stathmin 2 0.0073824
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.00737031
TMEM243 transmembrane protein 243, mitochondrial 0.00734423
LY6D lymphocyte antigen 6 complex, locus D 0.0073394
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 0.00732756
CLIC5 chloride intracellular channel 5 0.00732199
CALR calreticulin 0.00731915
TRAM1 translocation associated membrane protein 1 0.00731717
YPEL5 yippee-like 5 (Drosophila) 0.00731026
EDN3 endothelin 3 0.0073045
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 0.00730171
ACVR2A activin A receptor, type IIA 0.00729877
SLPI secretory leukocyte peptidase inhibitor 0.00727786
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 0.00725789
TPM2 tropomyosin 2 (beta) 0.0072487
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.00724049
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 0.00723776
ARMCX2 armadillo repeat containing, X-linked 2 0.00721979
SAT1 spermidine/spermine N1-acetyltransferase 1 0.00720581
ELL2 elongation factor, RNA polymerase II, 2 0.00720352
AKAP12 A kinase (PRKA) anchor protein 12 0.0071912
ANGPT1 angiopoietin 1 0.00717169
SRGN serglycin 0.00715313
CNTN1 contactin 1 0.0071397
ITGB6 integrin, beta 6 0.00713537
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 0.0071345
CORO1C coronin, actin binding protein, 1C 0.00713032
PADI2 peptidyl arginine deiminase, type II 0.00712944
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 0.00712838
GPC4 glypican 4 0.00712767
CTSG cathepsin G 0.00712328
SAMD9 sterile alpha motif domain containing 9 0.00711455
NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa 0.00710171
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.00709459
TLR4 toll-like receptor 4 0.00709217
USP18 ubiquitin specific peptidase 18 0.00708263

decreased expression

Symbol Name Standardized Value
WDR7 WD repeat domain 7 -0.0260679
DEGS1 delta(4)-desaturase, sphingolipid 1 -0.0163652
LEF1 lymphoid enhancer-binding factor 1 -0.0143536
JPT2 Jupiter microtubule associated homolog 2 -0.0138387
BGN biglycan -0.013328
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.0131309
ELOVL5 ELOVL fatty acid elongase 5 -0.0127327
TNS3 tensin 3 -0.0123804
GUSB glucuronidase, beta -0.0123241
RAPSN receptor-associated protein of the synapse -0.0122363
AEBP1 AE binding protein 1 -0.012104
TMSB15A thymosin beta 15a -0.0111929
TGFB3 transforming growth factor, beta 3 -0.0111544
RRAGA Ras-related GTP binding A -0.0111166
COL9A2 collagen, type IX, alpha 2 -0.0110426
FASN fatty acid synthase -0.0109495
TPSAB1 tryptase alpha/beta 1 -0.010778
TYMS thymidylate synthetase -0.0107267
COL18A1 collagen, type XVIII, alpha 1 -0.0107265
MDC1 mediator of DNA-damage checkpoint 1 -0.0105913
ADCY1 adenylate cyclase 1 (brain) -0.0105808
IL27RA interleukin 27 receptor, alpha -0.0105633
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 -0.0104963
NID2 nidogen 2 (osteonidogen) -0.0104816
IGF1 insulin-like growth factor 1 (somatomedin C) -0.0104292
CDC7 cell division cycle 7 -0.0103623
RXRA retinoid X receptor, alpha -0.0103615
FBLN1 fibulin 1 -0.0103061
PDGFC platelet derived growth factor C -0.0103052
NSD2 nuclear receptor binding SET domain protein 2 -0.0102711
JAG1 jagged 1 -0.0102573
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0102561
VEGFA vascular endothelial growth factor A -0.0101888
ADGRF5 adhesion G protein-coupled receptor F5 -0.0101184
CD93 CD93 molecule -0.0100756
CHKB choline kinase beta -0.0100695
THAP12 THAP domain containing 12 -0.0100168
SIDT2 SID1 transmembrane family, member 2 -0.00998324
SRRM2 serine/arginine repetitive matrix 2 -0.00994603
CDH1 cadherin 1, type 1, E-cadherin (epithelial) -0.00994063
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.00992387
RNF144A ring finger protein 144A -0.0099031
TSPAN7 tetraspanin 7 -0.00978456
SLIT2 slit homolog 2 (Drosophila) -0.00971659
KIF18B kinesin family member 18B -0.00971501
VWF von Willebrand factor -0.00960839
PRKDC protein kinase, DNA-activated, catalytic polypeptide -0.0096037
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) -0.00959151
UBR4 ubiquitin protein ligase E3 component n-recognin 4 -0.00956274
DYNLL1 dynein, light chain, LC8-type 1 -0.00955361
CROCCP2 ciliary rootlet coiled-coil, rootletin pseudogene 2 -0.00953952
FADS1 fatty acid desaturase 1 -0.00941812
NBPF10 neuroblastoma breakpoint family, member 10 -0.00941039
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b -0.00936597
CCL19 chemokine (C-C motif) ligand 19 -0.00934896
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -0.00932662
KDM5D lysine (K)-specific demethylase 5D -0.00929075
TIMP3 TIMP metallopeptidase inhibitor 3 -0.00919325
NELL2 NEL-like 2 (chicken) -0.00919222
RERE arginine-glutamic acid dipeptide (RE) repeats -0.00916103
ASPN asporin -0.00912417
APOD apolipoprotein D -0.00903429
COL6A2 collagen, type VI, alpha 2 -0.00887496
KLK2 kallikrein-related peptidase 2 -0.00884434
TUBB2B tubulin, beta 2B class IIb -0.00884116
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) -0.00884095
APOLD1 apolipoprotein L domain containing 1 -0.00878298
SETBP1 SET binding protein 1 -0.00877373
KRT14 keratin 14, type I -0.00876006
ZNF532 zinc finger protein 532 -0.00873226
AGR2 anterior gradient 2 -0.00867836
SYNGR3 synaptogyrin 3 -0.00867394
PTN pleiotrophin -0.00866437
LMNB2 lamin B2 -0.00864494
LRRC15 leucine rich repeat containing 15 -0.00864322
TARDBP TAR DNA binding protein -0.00859887
FEN1 flap structure-specific endonuclease 1 -0.00858626
PLXNA1 plexin A1 -0.00857318
TARP TCR gamma alternate reading frame protein -0.00853229
ADARB1 adenosine deaminase, RNA-specific, B1 -0.00849992
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 -0.00847876
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) -0.00847778
PRRC2A proline-rich coiled-coil 2A -0.00846857
CNTNAP2 contactin associated protein-like 2 -0.00845206
KLK3 kallikrein-related peptidase 3 -0.00841335
EML3 echinoderm microtubule associated protein like 3 -0.00837051
IGFBP5 insulin-like growth factor binding protein 5 -0.0083244
NDC80 NDC80 kinetochore complex component -0.00828392
FUS FUS RNA binding protein -0.00825871
DDAH1 dimethylarginine dimethylaminohydrolase 1 -0.00822633
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) -0.00818082
ARID1A AT rich interactive domain 1A (SWI-like) -0.00817926
ANKRD17 ankyrin repeat domain 17 -0.0081144
ZNF217 zinc finger protein 217 -0.00809838
ACACA acetyl-CoA carboxylase alpha -0.00809043
HELLS helicase, lymphoid-specific -0.00808362
NUP50 nucleoporin 50kDa -0.00807111
CD320 CD320 molecule -0.00806763
ACADVL acyl-CoA dehydrogenase, very long chain -0.00806209
MPHOSPH9 M-phase phosphoprotein 9 -0.00804391
COL16A1 collagen, type XVI, alpha 1 -0.00803308
HSPG2 heparan sulfate proteoglycan 2 -0.00803194
MFHAS1 malignant fibrous histiocytoma amplified sequence 1 -0.00799729
CAV1 caveolin 1, caveolae protein, 22kDa -0.0079972
IGFBP1 insulin-like growth factor binding protein 1 -0.00796213
CCNF cyclin F -0.00795177
MYH10 myosin, heavy chain 10, non-muscle -0.00794272
PAN2 PAN2 poly(A) specific ribonuclease subunit -0.00794196
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) -0.00792825
HDAC4 histone deacetylase 4 -0.00787658
SLC39A6 solute carrier family 39 (zinc transporter), member 6 -0.00785679
CYTL1 cytokine-like 1 -0.00784875
ZBTB18 zinc finger and BTB domain containing 18 -0.00784177
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 -0.00783645
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) -0.00783248
OLFML2B olfactomedin-like 2B -0.00781201
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -0.00779216
CUX2 cut-like homeobox 2 -0.00778877
ZNF266 zinc finger protein 266 -0.00775266
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 -0.00772495
NEFH neurofilament, heavy polypeptide -0.00771658
SORD sorbitol dehydrogenase -0.0076978
CXCL13 chemokine (C-X-C motif) ligand 13 -0.00768889
SPEN spen family transcriptional repressor -0.00767306
OPN3 opsin 3 -0.007673
KDR kinase insert domain receptor -0.00764899
NCAPD3 non-SMC condensin II complex, subunit D3 -0.00762402
TTI1 TELO2 interacting protein 1 -0.00760502
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1 -0.00760134
PTBP1 polypyrimidine tract binding protein 1 -0.00758433
ZC3H4 zinc finger CCCH-type containing 4 -0.00757897
FOXM1 forkhead box M1 -0.00757291
TSPAN4 tetraspanin 4 -0.00755832
TGOLN2 trans-golgi network protein 2 -0.00755722
DGS2 DiGeorge syndrome/velocardiofacial syndrome complex 2 -0.00755164
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -0.00754576
TM9SF3 transmembrane 9 superfamily member 3 -0.00754474
THBS4 thrombospondin 4 -0.00751088
NVL nuclear VCP-like -0.00751041
CLEC11A C-type lectin domain family 11, member A -0.00749559
NUAK1 NUAK family, SNF1-like kinase, 1 -0.00749371
LBR lamin B receptor -0.00749049
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 -0.00749044
INSIG1 insulin induced gene 1 -0.00748562
RACGAP1 Rac GTPase activating protein 1 -0.00747097
IGHMBP2 immunoglobulin mu binding protein 2 -0.00746084
TADA2A transcriptional adaptor 2A -0.00744712
SNAI2 snail family zinc finger 2 -0.0074455
FAM169A family with sequence similarity 169, member A -0.00743965
TAGLN transgelin -0.00743871
IPO9 importin 9 -0.00741688
NID1 nidogen 1 -0.00740912
SOCS1 suppressor of cytokine signaling 1 -0.00740458
RTN1 reticulon 1 -0.00740151
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 -0.00739199
GNMT glycine N-methyltransferase -0.00736661
AOC3 amine oxidase, copper containing 3 -0.00735904
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 -0.00735606
ZBED1 zinc finger, BED-type containing 1 -0.00735477
NUSAP1 nucleolar and spindle associated protein 1 -0.00735007
BAHCC1 BAH domain and coiled-coil containing 1 -0.00734859
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3 -0.00734691
SIRT3 sirtuin 3 -0.00733573
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 -0.00732154
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 -0.00731429
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.00727062
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 -0.00726951
NOTCH2 notch 2 -0.00726319
TRRAP transformation/transcription domain-associated protein -0.00725894
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1 -0.00722548
BRD3 bromodomain containing 3 -0.00722009
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4 -0.00721854
TBL1X transducin (beta)-like 1X-linked -0.00721677
PRKCZ protein kinase C, zeta -0.00721367
UBE2C ubiquitin-conjugating enzyme E2C -0.00721001
NPC1 Niemann-Pick disease, type C1 -0.00720221
TLE2 transducin-like enhancer of split 2 -0.00719772
LAMA5 laminin, alpha 5 -0.00719367
FUBP1 far upstream element (FUSE) binding protein 1 -0.00719241
ACAD8 acyl-CoA dehydrogenase family, member 8 -0.0071847
CS citrate synthase -0.00718167
NOTCH3 notch 3 -0.00717123
RBM47 RNA binding motif protein 47 -0.00717089
ALOX15B arachidonate 15-lipoxygenase, type B -0.00716939
ACSL3 acyl-CoA synthetase long-chain family member 3 -0.00716821
MAZ MYC-associated zinc finger protein (purine-binding transcription factor) -0.00715236
TMEM106C transmembrane protein 106C -0.00714343
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) -0.00713533
BASP1 brain abundant, membrane attached signal protein 1 -0.00711424
ZBTB16 zinc finger and BTB domain containing 16 -0.00710529
PLD3 phospholipase D family, member 3 -0.00709486
FXYD6 FXYD domain containing ion transport regulator 6 -0.00709303
PIKFYVE phosphoinositide kinase, FYVE finger containing -0.00708828
SPARCL1 SPARC-like 1 (hevin) -0.00708778
KIF14 kinesin family member 14 -0.00707546
PAPOLG poly(A) polymerase gamma -0.00707029
SLC26A2 solute carrier family 26 (anion exchanger), member 2 -0.00706118
COMP cartilage oligomeric matrix protein -0.00705593
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble -0.00701949
DPY19L1 dpy-19-like 1 (C. elegans) -0.00700981
LGSN lengsin, lens protein with glutamine synthetase domain -0.00700847
ATP9B ATPase, class II, type 9B -0.00700395
SNX1 sorting nexin 1 -0.00700332
PAEP progestagen-associated endometrial protein -0.00699909
MICALL2 MICAL-like 2 -0.00699534
C2CD5 C2 calcium-dependent domain containing 5 -0.00699206
MATN2 matrilin 2 -0.00697832
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -0.00697035
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -0.00696046
IRS1 insulin receptor substrate 1 -0.00695558
NAP1L2 nucleosome assembly protein 1-like 2 -0.00694463
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 -0.00694237
SMG7 SMG7 nonsense mediated mRNA decay factor -0.00690984
CHN2 chimerin 2 -0.00690666
SCUBE2 signal peptide, CUB domain, EGF-like 2 -0.00690649
CCNI cyclin I -0.00689673
PHKA2 phosphorylase kinase, alpha 2 (liver) -0.00688107
RRBP1 ribosome binding protein 1 -0.00687876
NAV2 neuron navigator 2 -0.00686971
CDC25B cell division cycle 25B -0.00686237
ELN elastin -0.00685419
CDK5RAP3 CDK5 regulatory subunit associated protein 3 -0.00683677
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase -0.0068316
SQLE squalene epoxidase -0.0068312
DGKZ diacylglycerol kinase, zeta -0.00682581
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae) -0.00681279
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.00678602
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 -0.00677899
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 -0.00677784
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1 -0.00677258
CBX5 chromobox homolog 5 -0.00674132
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa -0.0067404
FKBP9 FK506 binding protein 9, 63 kDa -0.00673708
CREB1 cAMP responsive element binding protein 1 -0.00673254
KANK2 KN motif and ankyrin repeat domains 2 -0.00672527
GGCT gamma-glutamylcyclotransferase -0.00672202
CTSV cathepsin V -0.00671407
HNRNPM heterogeneous nuclear ribonucleoprotein M -0.00670859
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 -0.00670613
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.00670001
PRPF8 pre-mRNA processing factor 8 -0.00669856
ANO1 anoctamin 1, calcium activated chloride channel -0.00669615
PFAS phosphoribosylformylglycinamidine synthase -0.00669126
FBXW2 F-box and WD repeat domain containing 2 -0.00668924
MYO1D myosin ID -0.00668741
AP2A2 adaptor-related protein complex 2, alpha 2 subunit -0.0066868
NCOR2 nuclear receptor corepressor 2 -0.00667976
MMP13 matrix metallopeptidase 13 -0.00667776
COCH cochlin -0.00667702