NFE2L2 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description nuclear factor, erythroid 2-like 2|This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] (NCBI Entrez Gene Database, 4780)
External Link https://ncbi.nlm.nih.gov/gene/4780
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Genes

500 genes differentially expressed following the NFE2L2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
ADO 2-aminoethanethiol (cysteamine) dioxygenase 0.0194108
MMP1 matrix metallopeptidase 1 0.0187692
GREM1 gremlin 1, DAN family BMP antagonist 0.0170114
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.0160981
RPS4Y1 ribosomal protein S4, Y-linked 1 0.01441
CXCL12 chemokine (C-X-C motif) ligand 12 0.0141286
BICC1 BicC family RNA binding protein 1 0.0134103
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 0.0131808
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 0.0131198
PROM1 prominin 1 0.0130646
INHBA inhibin, beta A 0.0129498
MFAP5 microfibrillar associated protein 5 0.0125168
GAS1 growth arrest-specific 1 0.0123761
JCHAIN joining chain of multimeric IgA and IgM 0.0123528
MOK MOK protein kinase 0.01212
ARMCX1 armadillo repeat containing, X-linked 1 0.0119302
COMP cartilage oligomeric matrix protein 0.0115932
VTCN1 V-set domain containing T cell activation inhibitor 1 0.0115077
POSTN periostin, osteoblast specific factor 0.0111017
HTRA1 HtrA serine peptidase 1 0.0110651
BEX4 brain expressed, X-linked 4 0.0110573
SGCE sarcoglycan, epsilon 0.0109496
DCN decorin 0.0108857
THBS2 thrombospondin 2 0.0107457
SIRPA signal-regulatory protein alpha 0.010734
LXN latexin 0.0104996
PDZK1IP1 PDZK1 interacting protein 1 0.010278
LPAR1 lysophosphatidic acid receptor 1 0.010186
CFB complement factor B 0.0101275
ANXA4 annexin A4 0.0099774
NT5E 5'-nucleotidase, ecto (CD73) 0.00989226
GSTM3 glutathione S-transferase mu 3 (brain) 0.0097839
TSPAN8 tetraspanin 8 0.0097683
LRRC15 leucine rich repeat containing 15 0.00969611
RECK reversion-inducing-cysteine-rich protein with kazal motifs 0.00968872
SRPX sushi-repeat containing protein, X-linked 0.00964119
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.00962127
AHR aryl hydrocarbon receptor 0.0094976
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.00946797
KRT23 keratin 23, type I 0.00943255
VEGFC vascular endothelial growth factor C 0.00932526
LCN2 lipocalin 2 0.00932155
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 0.00919428
FAM171A1 family with sequence similarity 171, member A1 0.00914318
OPTN optineurin 0.00910076
VCAM1 vascular cell adhesion molecule 1 0.00909017
DEFB1 defensin, beta 1 0.00907196
BASP1 brain abundant, membrane attached signal protein 1 0.00900647
ADD3 adducin 3 (gamma) 0.00899307
PDGFD platelet derived growth factor D 0.00897575
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha 0.00894144
TSPYL5 TSPY-like 5 0.00883071
COL10A1 collagen, type X, alpha 1 0.00880771
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 0.00875347
DPYSL3 dihydropyrimidinase-like 3 0.00873049
ARMCX2 armadillo repeat containing, X-linked 2 0.00873042
CTSD cathepsin D 0.00867976
PLXNC1 plexin C1 0.0086354
SFRP1 secreted frizzled-related protein 1 0.0085345
S100A8 S100 calcium binding protein A8 0.00838944
CAVIN3 caveolae associated protein 3 0.00835851
FST follistatin 0.00834552
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.00832594
GSPT2 G1 to S phase transition 2 0.00832298
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A 0.00829179
IPO13 importin 13 0.00828529
ATP10A ATPase, class V, type 10A 0.00822064
LY75 lymphocyte antigen 75 0.00821255
SOX9 SRY (sex determining region Y)-box 9 0.00818054
NID2 nidogen 2 (osteonidogen) 0.00814401
LOX lysyl oxidase 0.00810719
FXYD2 FXYD domain containing ion transport regulator 2 0.00806317
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 0.00803961
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 0.00800313
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 0.00794638
AKT3 v-akt murine thymoma viral oncogene homolog 3 0.0079421
VCAN versican 0.00792614
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.00791111
ZFPM2 zinc finger protein, FOG family member 2 0.00789089
BBX bobby sox homolog (Drosophila) 0.00787174
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 0.00784848
SGK1 serum/glucocorticoid regulated kinase 1 0.00782861
PPIF peptidylprolyl isomerase F 0.00782472
TOX3 TOX high mobility group box family member 3 0.00781526
THBS1 thrombospondin 1 0.00778501
VNN1 vanin 1 0.00777224
SNAI2 snail family zinc finger 2 0.00770705
THBS3 thrombospondin 3 0.00766505
NNMT nicotinamide N-methyltransferase 0.00766426
KLK5 kallikrein-related peptidase 5 0.00763161
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) 0.00758567
TM4SF1 transmembrane 4 L six family member 1 0.00757464
PFKP phosphofructokinase, platelet 0.00754265
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 0.00744337
GNG11 guanine nucleotide binding protein (G protein), gamma 11 0.0074286
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.0074277
EGR2 early growth response 2 0.00742324
DEPTOR DEP domain containing MTOR-interacting protein 0.00742187
HDAC9 histone deacetylase 9 0.00736404
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) 0.00734442
SUGCT succinyl-CoA:glutarate-CoA transferase 0.00727968
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14 0.00722248
CEL carboxyl ester lipase 0.0071628
RHOBTB1 Rho-related BTB domain containing 1 0.00716132
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase 0.00714089
GPR137B G protein-coupled receptor 137B 0.00713754
DIPK1A divergent protein kinase domain 1A 0.0070775
OLFM4 olfactomedin 4 0.0070749
IL7R interleukin 7 receptor 0.0070387
LY96 lymphocyte antigen 96 0.00703689
SULF1 sulfatase 1 0.00698519
ZSCAN18 zinc finger and SCAN domain containing 18 0.00697901
RTN2 reticulon 2 0.00697366
ADAMDEC1 ADAM-like, decysin 1 0.00697064
LUM lumican 0.00696268
TFPI2 tissue factor pathway inhibitor 2 0.00694612
SLIT1 slit homolog 1 (Drosophila) 0.00692134
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) 0.00690092
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.00689996
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 0.00688828
KLF10 Kruppel-like factor 10 0.00685726
SCG5 secretogranin V 0.00684054
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.0068232
LRRC8D leucine rich repeat containing 8 family, member D 0.00682016
TFEC transcription factor EC 0.00680158
LPIN1 lipin 1 0.0067881
CLINT1 clathrin interactor 1 0.0067681
FHOD3 formin homology 2 domain containing 3 0.00675518
ARHGAP29 Rho GTPase activating protein 29 0.00670913
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1 0.00670867
SYNE3 spectrin repeat containing, nuclear envelope family member 3 0.0066962
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.00669513
FABP4 fatty acid binding protein 4, adipocyte 0.00667668
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 0.00667397
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 0.00664711
GLS glutaminase 0.0066115
ZG16 zymogen granule protein 16 0.00660699
TNFRSF17 tumor necrosis factor receptor superfamily, member 17 0.00657066
GUCA2A guanylate cyclase activator 2A (guanylin) 0.00653693
MIR22HG MIR22 host gene 0.00653025
SPINK1 serine peptidase inhibitor, Kazal type 1 0.00652442
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 0.00650893
FOS FBJ murine osteosarcoma viral oncogene homolog 0.00648794
PDE4DIP phosphodiesterase 4D interacting protein 0.00647526
MAMLD1 mastermind-like domain containing 1 0.00641228
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 0.00641097
PDZRN3 PDZ domain containing ring finger 3 0.00640784
ANK2 ankyrin 2, neuronal 0.0063784
ZNF93 zinc finger protein 93 0.00635461
GPNMB glycoprotein (transmembrane) nmb 0.00635144
HBD hemoglobin, delta 0.00632436
MARCKS myristoylated alanine-rich protein kinase C substrate 0.00632225
SPHK1 sphingosine kinase 1 0.00630976
ASPA aspartoacylase 0.00630544
APOD apolipoprotein D 0.00624712
EPYC epiphycan 0.00622674
PLAU plasminogen activator, urokinase 0.00622064
SLC38A2 solute carrier family 38, member 2 0.0062176
BAMBI BMP and activin membrane-bound inhibitor 0.00619594
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) 0.00617926
PRKACB protein kinase, cAMP-dependent, catalytic, beta 0.00616545
SH3BGRL SH3 domain binding glutamate-rich protein like 0.00615395
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase 0.00614789
CRYAB crystallin, alpha B 0.00614344
C5ORF30 chromosome 5 open reading frame 30 0.00612185
LTF lactotransferrin 0.00612107
NOTCH1 notch 1 0.00612073
RAB29 RAB29, member RAS oncogene family 0.0061068
OAT ornithine aminotransferase 0.00610576
MIA melanoma inhibitory activity 0.00607467
UMOD uromodulin 0.00607056
TSLIG3A tRNA splicing ligase complex subunit 3A 0.00606354
LDOC1 leucine zipper, down-regulated in cancer 1 0.00605492
PLCL1 phospholipase C-like 1 0.00604664
GMPR guanosine monophosphate reductase 0.00604489
TSPO translocator protein (18kDa) 0.00604483
SOX11 SRY (sex determining region Y)-box 11 0.00603603
IER5 immediate early response 5 0.00602037
ERLIN1 ER lipid raft associated 1 0.00597639
MCTP1 multiple C2 domains, transmembrane 1 0.00596393
GAS6 growth arrest-specific 6 0.00596112
TXNDC9 thioredoxin domain containing 9 0.00594021
MN1 meningioma (disrupted in balanced translocation) 1 0.0059248
SCGB1D2 secretoglobin, family 1D, member 2 0.00592253
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 0.00590802
SLAMF7 SLAM family member 7 0.00589777
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 0.00588222
TNC tenascin C 0.00585884
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 0.00585342
DPP4 dipeptidyl-peptidase 4 0.00584995
CD200 CD200 molecule 0.00584675
RRAGD Ras-related GTP binding D 0.00583159
CLTB clathrin, light chain B 0.00582442
NUAK1 NUAK family, SNF1-like kinase, 1 0.00581351
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.00580546
LRP2 low density lipoprotein receptor-related protein 2 0.00580014
DPEP1 dipeptidase 1 (renal) 0.00578584
PHACTR2 phosphatase and actin regulator 2 0.00578313
SOCS5 suppressor of cytokine signaling 5 0.00577593
CDH16 cadherin 16, KSP-cadherin 0.00577184
LGALS2 lectin, galactoside-binding, soluble, 2 0.00571776
ATP13A3 ATPase type 13A3 0.00571297
GPX7 glutathione peroxidase 7 0.00569111
ANGPTL2 angiopoietin-like 2 0.00569012
DOK5 docking protein 5 0.00565493
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 0.0056462
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 0.00563501
DCT dopachrome tautomerase 0.00563137
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 0.00561934
NOX4 NADPH oxidase 4 0.00561859
PLK2 polo-like kinase 2 0.00559226
FAM117A family with sequence similarity 117, member A 0.00559126
CALB1 calbindin 1, 28kDa 0.00557712
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 0.00556726
CRIP2 cysteine-rich protein 2 0.00556049
ACAA1 acetyl-CoA acyltransferase 1 0.0055576
KLHL3 kelch-like family member 3 0.00555638
RPS27L ribosomal protein S27-like 0.00553538
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 0.00551363
AKAP8 A kinase (PRKA) anchor protein 8 0.00550339
FNBP1 formin binding protein 1 0.00549748
HINT1 histidine triad nucleotide binding protein 1 0.00549417
GSDME gasdermin E 0.00549312
NME5 NME/NM23 family member 5 0.00548668
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.00546981
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) 0.00546477
PBLD phenazine biosynthesis-like protein domain containing 0.00546342
ZNF91 zinc finger protein 91 0.00545971
JRKL JRK-like 0.00544779
ALCAM activated leukocyte cell adhesion molecule 0.00544134
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 0.00543842
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 0.00543225
NVL nuclear VCP-like 0.00542945
SLC26A2 solute carrier family 26 (anion exchanger), member 2 0.00541953
CREBL2 cAMP responsive element binding protein-like 2 0.00540816
WIPF1 WAS/WASL interacting protein family, member 1 0.00538877
CEP170 centrosomal protein 170kDa 0.00537626
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila) 0.0053592
COL11A1 collagen, type XI, alpha 1 0.0053584
TUBA1A tubulin, alpha 1a 0.00534394
CAMP cathelicidin antimicrobial peptide 0.00534169
ZCCHC24 zinc finger, CCHC domain containing 24 0.00531166
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.00530847
HMGN3 high mobility group nucleosomal binding domain 3 0.00528977
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa 0.00528946
NPAS2 neuronal PAS domain protein 2 0.00528252
CCND1 cyclin D1 0.00528106
CLDN8 claudin 8 0.00527113
PDGFRL platelet-derived growth factor receptor-like 0.00527075
G0S2 G0/G1 switch 2 0.00526396

decreased expression

Symbol Name Standardized Value
GLUL glutamate-ammonia ligase -0.0156051
S100P S100 calcium binding protein P -0.0154635
HSPB1 heat shock 27kDa protein 1 -0.0146811
AQP3 aquaporin 3 (Gill blood group) -0.0145122
METRN meteorin, glial cell differentiation regulator -0.0141672
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -0.0123099
MSX1 msh homeobox 1 -0.0120121
RHOB ras homolog family member B -0.0117996
XIC X chromosome inactivation center -0.0117311
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.0113744
DIO2 deiodinase, iodothyronine, type II -0.0108179
ANO1 anoctamin 1, calcium activated chloride channel -0.0105147
S100A2 S100 calcium binding protein A2 -0.01036
PGC progastricsin (pepsinogen C) -0.0102836
SPARCL1 SPARC-like 1 (hevin) -0.0102512
PTCH1 patched 1 -0.0100845
CTSH cathepsin H -0.0100008
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta -0.0099542
SORD sorbitol dehydrogenase -0.00962705
C1QB complement component 1, q subcomponent, B chain -0.00950319
FGFR3 fibroblast growth factor receptor 3 -0.0094871
VWF von Willebrand factor -0.0093728
KRT13 keratin 13, type I -0.00930163
CD163 CD163 molecule -0.00920796
YBX3 Y box binding protein 3 -0.00917406
LY6D lymphocyte antigen 6 complex, locus D -0.00911041
CD14 CD14 molecule -0.00898191
PIR pirin (iron-binding nuclear protein) -0.00886676
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -0.00885743
CST3 cystatin C -0.00863056
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 -0.00856216
FBXO11 F-box protein 11 -0.00852065
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 -0.00850598
GCLC glutamate-cysteine ligase, catalytic subunit -0.0085049
ERBB3 erb-b2 receptor tyrosine kinase 3 -0.00840677
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) -0.00840291
NES nestin -0.00828144
DHRS3 dehydrogenase/reductase (SDR family) member 3 -0.008265
HOPX HOP homeobox -0.00824289
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 -0.00820475
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) -0.00818777
MYBPC1 myosin binding protein C, slow type -0.00816323
RRAGA Ras-related GTP binding A -0.00814888
MAOA monoamine oxidase A -0.00804881
CD320 CD320 molecule -0.00803949
LEF1 lymphoid enhancer-binding factor 1 -0.00800181
CAV1 caveolin 1, caveolae protein, 22kDa -0.00799922
COPS7A COP9 signalosome subunit 7A -0.007946
GPM6B glycoprotein M6B -0.00785471
ALOX5AP arachidonate 5-lipoxygenase-activating protein -0.00785125
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 -0.00783897
CHPT1 choline phosphotransferase 1 -0.00778884
CD9 CD9 molecule -0.00777513
TNNC1 troponin C type 1 (slow) -0.00777021
YEATS4 YEATS domain containing 4 -0.00772854
C1QA complement component 1, q subcomponent, A chain -0.00770936
CPM carboxypeptidase M -0.00768402
MPPED2 metallophosphoesterase domain containing 2 -0.00765766
TMEM100 transmembrane protein 100 -0.00755721
MGP matrix Gla protein -0.00751895
RGCC regulator of cell cycle -0.00747661
CAPZB capping protein (actin filament) muscle Z-line, beta -0.00739153
AQP4 aquaporin 4 -0.00736448
KRT6A keratin 6A, type II -0.00736109
IFI44L interferon-induced protein 44-like -0.0073175
ALOX5 arachidonate 5-lipoxygenase -0.00729041
TAGLN2 transgelin 2 -0.00728657
RNF167 ring finger protein 167 -0.00727701
SFTPD surfactant protein D -0.00726695
SRSF1 serine/arginine-rich splicing factor 1 -0.0072657
LPCAT1 lysophosphatidylcholine acyltransferase 1 -0.00720466
HSPB8 heat shock 22kDa protein 8 -0.00719313
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) -0.00717915
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) -0.00717264
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 -0.00716528
A2M alpha-2-macroglobulin -0.00715647
CD99 CD99 molecule -0.00708796
TYROBP TYRO protein tyrosine kinase binding protein -0.00707313
LRP4 low density lipoprotein receptor-related protein 4 -0.00704738
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -0.00701203
RHOA ras homolog family member A -0.00699975
MX1 MX dynamin-like GTPase 1 -0.00699117
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) -0.00698412
CNPY3 canopy FGF signaling regulator 3 -0.00696875
AGR2 anterior gradient 2 -0.0069522
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 -0.00694197
PDE8B phosphodiesterase 8B -0.00691633
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 -0.00690428
STXBP6 syntaxin binding protein 6 (amisyn) -0.00689147
TACSTD2 tumor-associated calcium signal transducer 2 -0.00687225
KRT18 keratin 18, type I -0.00685461
TBL1X transducin (beta)-like 1X-linked -0.00681638
ZBTB35 zinc finger and BTB domain containing 35 -0.00681384
SLC39A6 solute carrier family 39 (zinc transporter), member 6 -0.00678403
MKNK1 MAP kinase interacting serine/threonine kinase 1 -0.00678387
USP18 ubiquitin specific peptidase 18 -0.00677137
ITM2A integral membrane protein 2A -0.00675671
GREB1 growth regulation by estrogen in breast cancer 1 -0.00675164
PDZD2 PDZ domain containing 2 -0.00673198
PGD phosphogluconate dehydrogenase -0.00672309
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 -0.00670448
AKAP13 A kinase (PRKA) anchor protein 13 -0.00670231
KRT1 keratin 1, type II -0.00666531
TIMELESS timeless circadian clock -0.00665686
CDH1 cadherin 1, type 1, E-cadherin (epithelial) -0.00659807
GAP43 growth associated protein 43 -0.00659798
PRF1 perforin 1 (pore forming protein) -0.00657301
RAB25 RAB25, member RAS oncogene family -0.00657192
CHIC2 cysteine-rich hydrophobic domain 2 -0.00656325
EZR ezrin -0.0065624
SPRR1B small proline-rich protein 1B -0.00654953
OPHN1 oligophrenin 1 -0.00654879
PTPN2 protein tyrosine phosphatase, non-receptor type 2 -0.00654349
ACTB actin, beta -0.00653994
TMPRSS11E transmembrane protease, serine 11E -0.00653956
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 -0.00646946
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.00642777
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa -0.00634119
CNTN1 contactin 1 -0.00633092
SIAH2 siah E3 ubiquitin protein ligase 2 -0.00631854
FERMT1 fermitin family member 1 -0.00626741
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa -0.00626331
SPC25 SPC25, NDC80 kinetochore complex component -0.00625528
SCNN1A sodium channel, non voltage gated 1 alpha subunit -0.00621718
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) -0.00620477
DSC2 desmocollin 2 -0.00619655
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 -0.00619625
CIT citron rho-interacting serine/threonine kinase -0.00617375
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 -0.00616791
FAM169A family with sequence similarity 169, member A -0.00614908
TRH thyrotropin-releasing hormone -0.00614903
HIST1H2BH histone cluster 1, H2bh -0.00612762
CD81 CD81 molecule -0.00611661
OAZ1 ornithine decarboxylase antizyme 1 -0.00607501
ADI1 acireductone dioxygenase 1 -0.00607052
HEATR1 HEAT repeat containing 1 -0.006067
ITGA6 integrin, alpha 6 -0.00606053
KANK2 KN motif and ankyrin repeat domains 2 -0.00605495
PLEK2 pleckstrin 2 -0.00605158
SFN stratifin -0.00604716
GNLY granulysin -0.00602763
PKP1 plakophilin 1 -0.00601818
DSTN destrin (actin depolymerizing factor) -0.00599802
ACP6 acid phosphatase 6, lysophosphatidic -0.00597692
MYO5C myosin VC -0.00597269
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide -0.0059712
HSPA4L heat shock 70kDa protein 4-like -0.00597001
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) -0.00596587
NUSAP1 nucleolar and spindle associated protein 1 -0.00596452
NEBL nebulette -0.00594639
HACD3 3-hydroxyacyl-CoA dehydratase 3 -0.00594612
SPTBN1 spectrin, beta, non-erythrocytic 1 -0.00592672
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa -0.00592536
PODXL podocalyxin-like -0.00592321
OIP5 Opa interacting protein 5 -0.00590562
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 -0.00590514
TUBGCP4 tubulin, gamma complex associated protein 4 -0.00586623
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) -0.00585072
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 -0.00584236
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) -0.00583207
PLBD1 phospholipase B domain containing 1 -0.00583123
RFC5 replication factor C (activator 1) 5, 36.5kDa -0.00582781
MARCO macrophage receptor with collagenous structure -0.00581608
HP haptoglobin -0.00579853
HMGB1 high mobility group box 1 -0.00579716
TOM1L1 target of myb1 (chicken)-like 1 -0.00577329
COPA coatomer protein complex, subunit alpha -0.00577154
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 -0.00576049
ABLIM1 actin binding LIM protein 1 -0.00575253
SMC1A structural maintenance of chromosomes 1A -0.00572459
MKI67 marker of proliferation Ki-67 -0.00572359
MAGEA1 melanoma antigen family A1 -0.00571189
GSR glutathione reductase -0.00571131
CAV2 caveolin 2 -0.00570624
FOXF1 forkhead box F1 -0.00570406
TUBB2A tubulin, beta 2A class IIa -0.00570132
PMF1 polyamine-modulated factor 1 -0.00567984
ISG15 ISG15 ubiquitin-like modifier -0.00566833
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) -0.00566787
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like -0.00564914
ACTA1 actin, alpha 1, skeletal muscle -0.0056481
ERP29 endoplasmic reticulum protein 29 -0.00564139
RBBP4 retinoblastoma binding protein 4 -0.00564005
DENND4C DENN/MADD domain containing 4C -0.00563177
S100A11 S100 calcium binding protein A11 -0.00562849
ACTC1 actin, alpha, cardiac muscle 1 -0.00562755
SFTPB surfactant protein B -0.00562287
NEK2 NIMA-related kinase 2 -0.00561674
MOCOS molybdenum cofactor sulfurase -0.00561127
GPR87 G protein-coupled receptor 87 -0.00561119
EIF1AX eukaryotic translation initiation factor 1A, X-linked -0.00560966
ABHD2 abhydrolase domain containing 2 -0.00560805
GLTP glycolipid transfer protein -0.00559688
TRIM29 tripartite motif containing 29 -0.00559005
BAG1 BCL2-associated athanogene -0.00558835
HPSE heparanase -0.00557565
CSF1R colony stimulating factor 1 receptor -0.00557202
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) -0.00556136
ADORA2B adenosine A2b receptor -0.00555166
TACC1 transforming, acidic coiled-coil containing protein 1 -0.00554887
CDC42SE1 CDC42 small effector 1 -0.0055457
CSTA cystatin A (stefin A) -0.0055412
GCLM glutamate-cysteine ligase, modifier subunit -0.00553938
PUDP pseudouridine 5'-phosphatase -0.00552915
COCH cochlin -0.00551239
COTL1 coactosin-like F-actin binding protein 1 -0.0055033
DAAM1 dishevelled associated activator of morphogenesis 1 -0.00550217
NQO1 NAD(P)H dehydrogenase, quinone 1 -0.00549793
S100A4 S100 calcium binding protein A4 -0.00548624
DUOX1 dual oxidase 1 -0.00546073
SLCO1B3 solute carrier organic anion transporter family, member 1B3 -0.00543646
TTN titin -0.00543526
ARG2 arginase 2 -0.00542472
TSPAN13 tetraspanin 13 -0.00542071
SCEL sciellin -0.00541989
PFN1 profilin 1 -0.0054186
DKFZP586I1420 uncharacterized protein DKFZp586I1420 -0.00541859
OASL 2'-5'-oligoadenylate synthetase-like -0.00541795
IFT74 intraflagellar transport 74 -0.00540698
FCGRT Fc fragment of IgG, receptor, transporter, alpha -0.00540583
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) -0.00538143
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 -0.0053724
RBM34 RNA binding motif protein 34 -0.0053684
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 -0.0053683
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.0053486
OLFM1 olfactomedin 1 -0.00533615
TXNIP thioredoxin interacting protein -0.00533482
DLG5 discs, large homolog 5 (Drosophila) -0.00532993
MKNK2 MAP kinase interacting serine/threonine kinase 2 -0.00531489
CTNNA2 catenin (cadherin-associated protein), alpha 2 -0.0052923
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon -0.00527603
ENO2 enolase 2 (gamma, neuronal) -0.00527106
CA12 carbonic anhydrase XII -0.00526429
PSD3 pleckstrin and Sec7 domain containing 3 -0.00526086
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 -0.0052607
SFTPC surfactant protein C -0.0052315
TNS3 tensin 3 -0.00522419
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 -0.00520564
MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta) -0.00520537
SPRED2 sprouty-related, EVH1 domain containing 2 -0.00518646
CCDC86 coiled-coil domain containing 86 -0.00518258
PDK3 pyruvate dehydrogenase kinase, isozyme 3 -0.00517838
GSTA4 glutathione S-transferase alpha 4 -0.00516643
BSG basigin (Ok blood group) -0.0051648
PCSK5 proprotein convertase subtilisin/kexin type 5 -0.00516476
RETREG3 reticulophagy regulator family member 3 -0.00516472
SDC2 syndecan 2 -0.00515587
PRDX2 peroxiredoxin 2 -0.00515553
GINS2 GINS complex subunit 2 (Psf2 homolog) -0.00515026
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 -0.00514483