NFE2L2 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description nuclear factor, erythroid 2-like 2|This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] (NCBI Entrez Gene Database, 4780)
External Link http://www.ncbi.nlm.nih.gov/gene/4780
Similar Terms
Downloads & Tools

Genes

60 interacting proteins for NFE2L2 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
AHR aryl hydrocarbon receptor
AKT1 v-akt murine thymoma viral oncogene homolog 1
ATF4 activating transcription factor 4
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
BPTF bromodomain PHD finger transcription factor
BRCA1 breast cancer 1, early onset
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHD6 chromodomain helicase DNA binding protein 6
COPS7A COP9 signalosome subunit 7A
CREB3 cAMP responsive element binding protein 3
CREBBP CREB binding protein
CUL3 cullin 3
EEF1G eukaryotic translation elongation factor 1 gamma
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
ENC1 ectodermal-neural cortex 1 (with BTB domain)
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1
GSK3B glycogen synthase kinase 3 beta
JUN jun proto-oncogene
JUND jun D proto-oncogene
KEAP1 kelch-like ECH-associated protein 1
KPNA3 karyopherin alpha 3 (importin alpha 4)
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MAFK v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MYC v-myc avian myelocytomatosis viral oncogene homolog
NCOR1 nuclear receptor corepressor 1
NCOR2 nuclear receptor corepressor 2
NFE2 nuclear factor, erythroid 2
NFE2L3 nuclear factor, erythroid 2-like 3
NQO1 NAD(P)H dehydrogenase, quinone 1
PGAM5 phosphoglycerate mutase family member 5
PMF1 polyamine-modulated factor 1
PPARG peroxisome proliferator-activated receptor gamma
PRKCA protein kinase C, alpha
PRKCD protein kinase C, delta
PRKCG protein kinase C, gamma
PRKCH protein kinase C, eta
PRKCQ protein kinase C, theta
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5
RARA retinoic acid receptor, alpha
RBMX RNA binding motif protein, X-linked
RNF4 ring finger protein 4
RPS27A ribosomal protein S27a
SIAH2 siah E3 ubiquitin protein ligase 2
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SQSTM1 sequestosome 1
SUMO1 small ubiquitin-like modifier 1
SUMO2 small ubiquitin-like modifier 2
SUMO3 small ubiquitin-like modifier 3
TRIM24 tripartite motif containing 24
UBC ubiquitin C
UBE2E2 ubiquitin-conjugating enzyme E2E 2
UBE2E3 ubiquitin-conjugating enzyme E2E 3
YY1 YY1 transcription factor