NFIB Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description nuclear factor I/B| (NCBI Entrez Gene Database, 4781)
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Genes

327 genes differentially expressed following the NFIB gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
ITGA8 integrin, alpha 8 3.16389
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 3.16389
KLB klotho beta 3.16389
CH25H cholesterol 25-hydroxylase 3.16389
LHX1 LIM homeobox 1 3.16389
KLK7 kallikrein-related peptidase 7 3.16389
RGS11 regulator of G-protein signaling 11 3.16389
AKR1D1 aldo-keto reductase family 1, member D1 3.16389
OR8H2 olfactory receptor, family 8, subfamily H, member 2 3.16389
DUXA double homeobox A 3.16389
WNK4 WNK lysine deficient protein kinase 4 3.16389
GPR12 G protein-coupled receptor 12 3.16389
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 3.16389
LONRF3 LON peptidase N-terminal domain and ring finger 3 3.16389
IL32 interleukin 32 3.16389
ANGPTL3 angiopoietin-like 3 3.16389
MIA melanoma inhibitory activity 3.16389
BIN2 bridging integrator 2 3.16389
ERAS ES cell expressed Ras 3.16389
PCDHAC1 protocadherin alpha subfamily C, 1 3.16389
MMP28 matrix metallopeptidase 28 3.16389
DPF3 D4, zinc and double PHD fingers, family 3 3.16389
NCKAP1L NCK-associated protein 1-like 3.16389
FRMD7 FERM domain containing 7 3.16389
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 3.16389
MFAP5 microfibrillar associated protein 5 3.16389
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 3.16389
CIROZ ciliated left-right organizer protein containing ZP-N domains 3.16389
GDA guanine deaminase 3.16389
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 3.09165
SIX1 SIX homeobox 1 3.09165
NR1H4 nuclear receptor subfamily 1, group H, member 4 3.09165
SERPINA11 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11 3.09165
SIX6 SIX homeobox 6 3.09165
SELPLG selectin P ligand 3.09165
MYBPHL myosin binding protein H-like 3.09165
OR5B12 olfactory receptor, family 5, subfamily B, member 12 3.09165
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 3.09165
TIFAB TRAF-interacting protein with forkhead-associated domain, family member B 3.09165
SLC46A3 solute carrier family 46, member 3 3.09165
MC4R melanocortin 4 receptor 3.09165
TLE7 TLE family member 7 3.09165
TRIM74 tripartite motif containing 74 3.09165
PTGFR prostaglandin F receptor (FP) 3.09165
ADAMTSL2 ADAMTS-like 2 3.09165
SNPH syntaphilin 3.09165
ZNF558 zinc finger protein 558 3.09165
ZNF705D zinc finger protein 705D 3.09165
UBA7 ubiquitin-like modifier activating enzyme 7 3.09165
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1 3.09165
SLC30A2 solute carrier family 30 (zinc transporter), member 2 3.09165
UCN2 urocortin 2 3.09165
ASB18 ankyrin repeat and SOCS box containing 18 3.09165
DNASE1L2 deoxyribonuclease I-like 2 3.09165
EPPIN epididymal peptidase inhibitor 3.09165
OSGIN1 oxidative stress induced growth inhibitor 1 3.09165
C8ORF48 chromosome 8 open reading frame 48 3.09165
SLC25A45 solute carrier family 25, member 45 3.09165
SLC25A41 solute carrier family 25, member 41 3.09165
OR2AG1 olfactory receptor, family 2, subfamily AG, member 1 (gene/pseudogene) 3.09165
GJB5 gap junction protein, beta 5, 31.1kDa 3.09165
PAX5 paired box 5 3.09165
HES3 hes family bHLH transcription factor 3 3.09165
TAS2R3 taste receptor, type 2, member 3 3.09165
SPMIP11 sperm microtubule inner protein 11 3.09165
SPATS1 spermatogenesis associated, serine-rich 1 3.09165
HAO2 hydroxyacid oxidase 2 (long chain) 3.09165
TAS2R60 taste receptor, type 2, member 60 3.09165
IFIT1B interferon-induced protein with tetratricopeptide repeats 1B 3.09165
ACSL6 acyl-CoA synthetase long-chain family member 6 3.09165
MYEOV myeloma overexpressed 3.09165
HTR3E 5-hydroxytryptamine (serotonin) receptor 3E, ionotropic 3.09165
ABCA9 ATP-binding cassette, sub-family A (ABC1), member 9 3.09165
SYT15 synaptotagmin XV 3.09165
ERVW-1 endogenous retrovirus group W, member 1 3.09165
SEPTIN14 septin 14 3.09165
PHF24 PHD finger protein 24 3.09165
SPATA31H1 SPATA31 subfamily H member 1 3.09165
C17ORF113 chromosome 17 open reading frame 113 3.09165
SMIM35 small integral membrane protein 35 3.09165
PEAK3 PEAK family member 3 3.09165
DEFB131B defensin beta 131B 3.09165
DYNLT4 dynein light chain Tctex-type 4 3.09165
SPATA46 spermatogenesis associated 46 3.09165
DERPC DERPC proline and glycine rich nuclear protein 3.09165
VSIR V-set immunoregulatory receptor 3.09165
LTK leukocyte receptor tyrosine kinase 3.09165
GPR83 G protein-coupled receptor 83 3.09165
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 3.09165
PCDHB13 protocadherin beta 13 3.09165
TLE6 transducin-like enhancer of split 6 3.09165
PTPRQ protein tyrosine phosphatase, receptor type, Q 3.09165
KLHL33 kelch-like family member 33 3.09165
PCDHA3 protocadherin alpha 3 3.09165
ACTL10 actin-like 10 3.09165
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) 3.09165
ACTRT1 actin-related protein T1 3.09165
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit 3.09165
NHLRC4 NHL repeat containing 4 3.09165
GDF10 growth differentiation factor 10 3.09165
PABPC1L2B poly(A) binding protein, cytoplasmic 1-like 2B 3.09165
RBM44 RNA binding motif protein 44 3.09165
CACNG2 calcium channel, voltage-dependent, gamma subunit 2 3.09165
CASP10 caspase 10, apoptosis-related cysteine peptidase 3.09165
CCR4 chemokine (C-C motif) receptor 4 3.09165
GJD2 gap junction protein, delta 2, 36kDa 3.09165
CREB3L3 cAMP responsive element binding protein 3-like 3 3.09165
CFAP45 cilia and flagella associated protein 45 3.09165
TBX5 T-box 5 3.09165
FAM3D family with sequence similarity 3, member D 3.09165
ACVRL1 activin A receptor type II-like 1 3.09165
ZNF703 zinc finger protein 703 3.09165
EPO erythropoietin 3.09165
ADAM2 ADAM metallopeptidase domain 2 3.09165
POTEJ POTE ankyrin domain family, member J 3.09165
CGB7 chorionic gonadotropin, beta polypeptide 7 3.09165
NUPR1 nuclear protein, transcriptional regulator, 1 3.09165
ISL2 ISL LIM homeobox 2 3.09165
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 3.09165
LAMP3 lysosomal-associated membrane protein 3 3.09165
IL1A interleukin 1, alpha 3.09165
PRTN3 proteinase 3 3.09165
NNMT nicotinamide N-methyltransferase 3.09165
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8 3.09165
TEX36 testis expressed 36 3.09165
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 3.09165
POU2AF1 POU class 2 associating factor 1 3.09165
TREH trehalase (brush-border membrane glycoprotein) 3.09165
GAGE10 G antigen 10 3.09165
GP1BB glycoprotein Ib (platelet), beta polypeptide 3.09165
POF1B premature ovarian failure, 1B 3.09165
EFCAB3 EF-hand calcium binding domain 3 3.09165
DQX1 DEAQ box RNA-dependent ATPase 1 3.09165
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1 3.09165
CPSF4L cleavage and polyadenylation specific factor 4-like 3.09165
RNASE11 ribonuclease, RNase A family, 11 (non-active) 3.09165
ZMYND15 zinc finger, MYND-type containing 15 3.09165
INHA inhibin, alpha 3.09165
ANKRD62 ankyrin repeat domain 62 3.09165
IL12A interleukin 12A 3.09165
FZD1 frizzled class receptor 1 3.09165
ADRA1A adrenoceptor alpha 1A 3.09165
PLA1A phospholipase A1 member A 3.09165
OR10G3 olfactory receptor, family 10, subfamily G, member 3 3.09165
C11ORF42 chromosome 11 open reading frame 42 3.09165
TTC29 tetratricopeptide repeat domain 29 3.09165
NWD2 NACHT and WD repeat domain containing 2 3.09165
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 3.09165
IL18R1 interleukin 18 receptor 1 3.09165
NMUR1 neuromedin U receptor 1 3.09165
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 3.09165
GALR3 galanin receptor 3 3.09165
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 3.09165
SLC39A12 solute carrier family 39 (zinc transporter), member 12 3.09165
SLC37A2 solute carrier family 37 (glucose-6-phosphate transporter), member 2 3.09165
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 3.09165
PNOC prepronociceptin 3.09165
SPAG6 sperm associated antigen 6 3.09165
FAIM2 Fas apoptotic inhibitory molecule 2 3.09165
IGIP IgA-inducing protein 3.09165
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 3.09165
LENEP lens epithelial protein 3.09165
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled 3.09165
SLC38A8 solute carrier family 38, member 8 3.09165
TRMT10A tRNA methyltransferase 10 homolog A (S. cerevisiae) 3.09165
NEUROD2 neuronal differentiation 2 3.09165
KLRK1 killer cell lectin-like receptor subfamily K, member 1 3.09165
BCL2L15 BCL2-like 15 3.09165
ZC2HC1B zinc finger, C2HC-type containing 1B 3.09165
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1 3.09165
CCDC87 coiled-coil domain containing 87 3.09165
MYADML2 myeloid-associated differentiation marker-like 2 3.09165
LANCL3 LanC lantibiotic synthetase component C-like 3 (bacterial) 3.09165
DROSHA drosha, ribonuclease type III 3.07086
TNS4 tensin 4 3.07014
CFAP65 cilia and flagella associated protein 65 3.03263
MYLK4 myosin light chain kinase family, member 4 2.97801
DDIAS DNA damage-induced apoptosis suppressor 2.96281
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase 2.95103
CLTC clathrin, heavy chain (Hc) 2.92518
BCLAF1 BCL2-associated transcription factor 1 2.78358
FBXL7 F-box and leucine-rich repeat protein 7 2.69797
DCAF16 DDB1 and CUL4 associated factor 16 2.67513
KPNA1 karyopherin alpha 1 (importin alpha 5) 2.66646
VAMP8 vesicle-associated membrane protein 8 2.66546
VTCN1 V-set domain containing T cell activation inhibitor 1 2.6637
ADI1 acireductone dioxygenase 1 2.61331
NOSTRIN nitric oxide synthase trafficking 2.60422
CYP4V2 cytochrome P450, family 4, subfamily V, polypeptide 2 2.59864
RBM38 RNA binding motif protein 38 2.56357
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 2.55749
RGN regucalcin 2.54951
FOXP3 forkhead box P3 2.54683
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa 2.5031
RENBP renin binding protein 2.46258
PYCR2 pyrroline-5-carboxylate reductase family, member 2 2.40078
PDLIM1 PDZ and LIM domain 1 2.39631
TRPC5 transient receptor potential cation channel, subfamily C, member 5 2.37818
NLRC3 NLR family, CARD domain containing 3 2.37126
COL9A1 collagen, type IX, alpha 1 2.36656
B3GNT9 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 2.3394
MMADHC methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria 2.25749
ZNF429 zinc finger protein 429 2.25215
FAAH2 fatty acid amide hydrolase 2 2.2489
LRFN5 leucine rich repeat and fibronectin type III domain containing 5 2.2489
GPHN gephyrin 2.2314
LMTK1 lemur tail kinase 1 2.14274
EPHA1 EPH receptor A1 2.13581
TBCB tubulin folding cofactor B 2.13465
FHOD3 formin homology 2 domain containing 3 2.1289
MRPL46 mitochondrial ribosomal protein L46 2.1289
KLHDC10 kelch domain containing 10 2.12597
MAP7 microtubule-associated protein 7 2.09944
RAMP3 receptor (G protein-coupled) activity modifying protein 3 2.08439
TET1 tet methylcytosine dioxygenase 1 2.08008
CREB3L1 cAMP responsive element binding protein 3-like 1 2.07604
ISOC2 isochorismatase domain containing 2 2.07549
NR2E3 nuclear receptor subfamily 2, group E, member 3 2.05576
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 2.05574
ACVR1C activin A receptor, type IC 2.05574
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha 2.04884
ATF3 activating transcription factor 3 2.0444
KTN1 kinectin 1 (kinesin receptor) 2.03301
C6ORF89 chromosome 6 open reading frame 89 2.00893
CHL1 cell adhesion molecule L1-like 2.00538
HBP1 HMG-box transcription factor 1 2.00538
EPHA3 EPH receptor A3 2.00538
UFSP2 UFM1-specific peptidase 2 2.00084

decreased expression

Symbol Name Standardized Value
LAG3 lymphocyte-activation gene 3 -3.16389
GHRHR growth hormone releasing hormone receptor -3.16389
KRT7 keratin 7, type II -3.16389
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) -3.16389
ZNF106 zinc finger protein 106 -3.09165
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) -3.09165
SH2D6 SH2 domain containing 6 -3.09165
SLC4A9 solute carrier family 4, sodium bicarbonate cotransporter, member 9 -3.09165
MUC6 mucin 6, oligomeric mucus/gel-forming -3.09165
APOH apolipoprotein H (beta-2-glycoprotein I) -3.09165
SLC23A3 solute carrier family 23, member 3 -3.09165
MYO16 myosin XVI -3.09165
CHD5 chromodomain helicase DNA binding protein 5 -3.09165
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C -3.09165
SYCE3 synaptonemal complex central element protein 3 -3.09165
DPPA3 developmental pluripotency associated 3 -3.09165
PARP15 poly (ADP-ribose) polymerase family, member 15 -3.09165
RLN1 relaxin 1 -3.09165
CRX cone-rod homeobox -3.09165
SLC23A1 solute carrier family 23 (ascorbic acid transporter), member 1 -3.09165
ZSWIM3 zinc finger, SWIM-type containing 3 -3.09165
NACA2 nascent polypeptide-associated complex alpha subunit 2 -3.09165
MAP1A microtubule-associated protein 1A -3.09165
C10ORF105 chromosome 10 open reading frame 105 -3.09165
TMEM238L transmembrane protein 238 like -3.09165
MINAR1 membrane integral NOTCH2 associated receptor 1 -3.09165
LOC112694756 uncharaterized LOC112694756 -3.09165
ODAD1 outer dynein arm docking complex subunit 1 -3.09165
SPATA22 spermatogenesis associated 22 -3.09165
TEP1 telomerase-associated protein 1 -3.09165
ALDH3B1 aldehyde dehydrogenase 3 family, member B1 -3.09165
CIMIP7 ciliary microtubule inner protein 7 -3.09165
CSTA cystatin A (stefin A) -3.09165
CCDC121 coiled-coil domain containing 121 -3.09165
C3ORF49 chromosome 3 open reading frame 49 -3.09165
S100A14 S100 calcium binding protein A14 -3.09165
GOLGA8H golgin A8 family, member H -3.09165
CDHR3 cadherin-related family member 3 -3.09165
ITM2C integral membrane protein 2C -3.09165
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 -3.08525
RUNDC3B RUN domain containing 3B -2.97265
SLC7A10 solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10 -2.97265
TMT1B thiol methyltransferase 1B -2.94863
ZFP2 ZFP2 zinc finger protein -2.92259
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 -2.87529
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 -2.86799
PLPPR1 phospholipid phosphatase related 1 -2.84962
HDAC8 histone deacetylase 8 -2.83371
ASMTL acetylserotonin O-methyltransferase-like -2.80327
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11 -2.76475
DHRS2 dehydrogenase/reductase (SDR family) member 2 -2.74703
NTMT2 N-terminal Xaa-Pro-Lys N-methyltransferase 2 -2.74703
RIPOR2 RHO family interacting cell polarization regulator 2 -2.69607
RHPN2 rhophilin, Rho GTPase binding protein 2 -2.66646
LPIN3 lipin 3 -2.66434
GADD45B growth arrest and DNA-damage-inducible, beta -2.61132
CRYAB crystallin, alpha B -2.60422
DEDD death effector domain containing -2.54951
IGDCC4 immunoglobulin superfamily, DCC subclass, member 4 -2.50509
ANXA2 annexin A2 -2.49534
NFIA nuclear factor I/A -2.47628
EYA4 EYA transcriptional coactivator and phosphatase 4 -2.4394
SAXO4 stabilizer of axonemal microtubules 4 -2.4394
NBPF26 neuroblastoma breakpoint family, member 26 -2.41889
TCP10L t-complex 10-like -2.32453
BCAN brevican -2.31551
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 -2.31551
H2BC8 H2B clustered histone 8 -2.25655
TBCD tubulin folding cofactor D -2.25617
PPA1 pyrophosphatase (inorganic) 1 -2.2489
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8 -2.23984
GJA1 gap junction protein, alpha 1, 43kDa -2.21755
GSTM2 glutathione S-transferase mu 2 (muscle) -2.21118
KIAA0319 KIAA0319 -2.1944
WDR77 WD repeat domain 77 -2.18418
PANK1 pantothenate kinase 1 -2.16787
CA5B carbonic anhydrase VB, mitochondrial -2.13465
ANTKMT adenine nucleotide translocase lysine methyltransferase -2.1289
CALCB calcitonin-related polypeptide beta -2.12705
REXO4 REX4, RNA exonuclease 4 homolog (S. cerevisiae) -2.1091
AKAP8L A kinase (PRKA) anchor protein 8-like -2.1091
SFI1 Sfi1 homolog, spindle assembly associated (yeast) -2.08532
CILK1 ciliogenesis associated kinase 1 -2.08532
CIMAP3 ciliary microtubule associated protein 3 -2.07196
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 -2.05841
PTPRD protein tyrosine phosphatase, receptor type, D -2.05537
EGLN3 egl-9 family hypoxia-inducible factor 3 -2.05478
CENPU centromere protein U -2.05239
WBP4 WW domain binding protein 4 -2.03478
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -2.03301
IDUA iduronidase, alpha-L- -2.03301
CCDC68 coiled-coil domain containing 68 -2.03301
NACAD NAC alpha domain containing -2.03301
OR2H2 olfactory receptor, family 2, subfamily H, member 2 -2.03301
ARHGAP9 Rho GTPase activating protein 9 -2.03301
FNDC5 fibronectin type III domain containing 5 -2.03301
FGF23 fibroblast growth factor 23 -2.03301
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit -2.02961
SHROOM3 shroom family member 3 -2.02961