| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1|This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009] (NCBI Entrez Gene Database, 4790) |
| External Link | https://ncbi.nlm.nih.gov/gene/4790 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the NFKB1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MMP1 | matrix metallopeptidase 1 | 0.0165428 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.0151838 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | 0.014679 |
| NID2 | nidogen 2 (osteonidogen) | 0.013563 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | 0.0131469 |
| IPO13 | importin 13 | 0.0127695 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase | 0.0125525 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | 0.0115403 |
| PCP4 | Purkinje cell protein 4 | 0.0115046 |
| LRRC15 | leucine rich repeat containing 15 | 0.011219 |
| FST | follistatin | 0.0108856 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | 0.010805 |
| THBS2 | thrombospondin 2 | 0.0105019 |
| MOK | MOK protein kinase | 0.0100983 |
| NUAK1 | NUAK family, SNF1-like kinase, 1 | 0.00977827 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.00967921 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.00963544 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) | 0.00944414 |
| SFRP4 | secreted frizzled-related protein 4 | 0.00932312 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.00931587 |
| SCG5 | secretogranin V | 0.00929038 |
| CPB1 | carboxypeptidase B1 (tissue) | 0.0091555 |
| COMP | cartilage oligomeric matrix protein | 0.00914475 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | 0.0089032 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.00888921 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00886333 |
| DACT1 | dishevelled-binding antagonist of beta-catenin 1 | 0.00879111 |
| MB | myoglobin | 0.00878012 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | 0.00871305 |
| ZFPM2 | zinc finger protein, FOG family member 2 | 0.00871077 |
| NNMT | nicotinamide N-methyltransferase | 0.00866393 |
| EXT1 | exostosin glycosyltransferase 1 | 0.00866064 |
| ASPN | asporin | 0.00862653 |
| PTK2B | protein tyrosine kinase 2 beta | 0.00852344 |
| SNX7 | sorting nexin 7 | 0.0085113 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | 0.00848246 |
| MAP7 | microtubule-associated protein 7 | 0.00847403 |
| PLK2 | polo-like kinase 2 | 0.00841374 |
| CHGB | chromogranin B | 0.00841309 |
| MRPL12 | mitochondrial ribosomal protein L12 | 0.00834139 |
| DGKZ | diacylglycerol kinase, zeta | 0.00830898 |
| CTSD | cathepsin D | 0.00829753 |
| APOC1 | apolipoprotein C-I | 0.00822099 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.00817206 |
| COL10A1 | collagen, type X, alpha 1 | 0.0081614 |
| PLN | phospholamban | 0.00810376 |
| PHACTR2 | phosphatase and actin regulator 2 | 0.00807385 |
| ANXA4 | annexin A4 | 0.00804869 |
| LMNB2 | lamin B2 | 0.00803324 |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 | 0.00801631 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.00798737 |
| PLXNC1 | plexin C1 | 0.00798131 |
| MCUB | mitochondrial calcium uniporter dominant negative subunit beta | 0.00789872 |
| SLC25A14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 | 0.007867 |
| PEG10 | paternally expressed 10 | 0.00785623 |
| TAGLN | transgelin | 0.00783584 |
| SLC38A1 | solute carrier family 38, member 1 | 0.00781388 |
| MFAP5 | microfibrillar associated protein 5 | 0.0077663 |
| AHR | aryl hydrocarbon receptor | 0.0077017 |
| TGFB3 | transforming growth factor, beta 3 | 0.00768896 |
| MLPH | melanophilin | 0.00764727 |
| EFHD2 | EF-hand domain family, member D2 | 0.00761336 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | 0.00759693 |
| PPP1R1A | protein phosphatase 1, regulatory (inhibitor) subunit 1A | 0.00757947 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.00757574 |
| RNPS1 | RNA binding protein S1, serine-rich domain | 0.00757095 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 | 0.00755638 |
| ASRGL1 | asparaginase like 1 | 0.00754284 |
| HEBP2 | heme binding protein 2 | 0.00754226 |
| CHGA | chromogranin A | 0.0075053 |
| G0S2 | G0/G1 switch 2 | 0.00750414 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.00748645 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.00748121 |
| TTR | transthyretin | 0.0074529 |
| DSE | dermatan sulfate epimerase | 0.00741604 |
| CYBA | cytochrome b-245, alpha polypeptide | 0.00740506 |
| NVL | nuclear VCP-like | 0.0073754 |
| REG1A | regenerating islet-derived 1 alpha | 0.00736104 |
| NOTCH2NL | notch 2 N-terminal like | 0.00733735 |
| EML3 | echinoderm microtubule associated protein like 3 | 0.00733464 |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 | 0.00733058 |
| TLN1 | talin 1 | 0.00731458 |
| ISYNA1 | inositol-3-phosphate synthase 1 | 0.00728438 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.00727963 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | 0.00717342 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | 0.00717281 |
| LOX | lysyl oxidase | 0.00713705 |
| FZD2 | frizzled class receptor 2 | 0.00713006 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | 0.00712517 |
| SCAND1 | SCAN domain containing 1 | 0.00712157 |
| LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | 0.00711385 |
| TFAM | transcription factor A, mitochondrial | 0.00711367 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | 0.00711093 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 | 0.00709018 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | 0.0070872 |
| HDAC9 | histone deacetylase 9 | 0.00703048 |
| HAUS2 | HAUS augmin-like complex, subunit 2 | 0.00699583 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | 0.00698502 |
| TLE5 | TLE family member 5, transcriptional modulator | 0.00696907 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | 0.00696507 |
| ZNF160 | zinc finger protein 160 | 0.00695782 |
| GOLGA8A | golgin A8 family, member A | 0.00694197 |
| DCN | decorin | 0.00694119 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.0069381 |
| ASGR2 | asialoglycoprotein receptor 2 | 0.00693084 |
| CAMKK2 | calcium/calmodulin-dependent protein kinase kinase 2, beta | 0.00692285 |
| ATP5F1D | ATP synthase F1 subunit delta | 0.00690963 |
| ZNF544 | zinc finger protein 544 | 0.00690039 |
| AURKB | aurora kinase B | 0.00689936 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.00689655 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 | 0.00687007 |
| PLCL2 | phospholipase C-like 2 | 0.00684071 |
| COL6A2 | collagen, type VI, alpha 2 | 0.00683904 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 0.00682747 |
| TIMM13 | translocase of inner mitochondrial membrane 13 homolog (yeast) | 0.00682694 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.00682205 |
| ABHD14A | abhydrolase domain containing 14A | 0.00682039 |
| PDLIM3 | PDZ and LIM domain 3 | 0.00680555 |
| TYMP | thymidine phosphorylase | 0.00680351 |
| RCAN2 | regulator of calcineurin 2 | 0.00680327 |
| DCT | dopachrome tautomerase | 0.00679507 |
| HTRA1 | HtrA serine peptidase 1 | 0.00677356 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0067553 |
| NEUROD1 | neuronal differentiation 1 | 0.00675263 |
| ELN | elastin | 0.00673299 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | 0.00672739 |
| LSP1 | lymphocyte-specific protein 1 | 0.00671998 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | 0.00671623 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.00671111 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | 0.00669566 |
| CELP | carboxyl ester lipase pseudogene | 0.00668934 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 | 0.00668857 |
| LXN | latexin | 0.0066765 |
| WTAP | Wilms tumor 1 associated protein | 0.00666666 |
| AXL | AXL receptor tyrosine kinase | 0.00665576 |
| CDCP1 | CUB domain containing protein 1 | 0.00665526 |
| ATP13A3 | ATPase type 13A3 | 0.00664031 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | 0.00663749 |
| SNAI2 | snail family zinc finger 2 | 0.00662774 |
| CCL2 | chemokine (C-C motif) ligand 2 | 0.00662759 |
| ZNF721 | zinc finger protein 721 | 0.00661414 |
| BSG | basigin (Ok blood group) | 0.00660124 |
| KIAA0930 | KIAA0930 | 0.0065757 |
| NPTX2 | neuronal pentraxin II | 0.0065676 |
| ST18 | suppression of tumorigenicity 18, zinc finger | 0.00655834 |
| TARDBP | TAR DNA binding protein | 0.0065473 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.00654672 |
| PHTF2 | putative homeodomain transcription factor 2 | 0.00653916 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.00653811 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.00653445 |
| FBXW12 | F-box and WD repeat domain containing 12 | 0.00649016 |
| BGN | biglycan | 0.00648399 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.00646934 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.00646933 |
| LOC283683 | uncharacterized LOC283683 | 0.00646138 |
| ZNF329 | zinc finger protein 329 | 0.00645375 |
| MYH11 | myosin, heavy chain 11, smooth muscle | 0.00642966 |
| AHSG | alpha-2-HS-glycoprotein | 0.00642081 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.00638634 |
| PLPP2 | phospholipid phosphatase 2 | 0.00638594 |
| PMP22 | peripheral myelin protein 22 | 0.00637706 |
| FAM114A1 | family with sequence similarity 114, member A1 | 0.00637501 |
| CHST1 | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 | 0.00635091 |
| POSTN | periostin, osteoblast specific factor | 0.00632879 |
| PGRMC2 | progesterone receptor membrane component 2 | 0.00632378 |
| FGL2 | fibrinogen-like 2 | 0.00631536 |
| GATA6 | GATA binding protein 6 | 0.00630936 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | 0.00630753 |
| SCGN | secretagogin, EF-hand calcium binding protein | 0.00630024 |
| TOB1 | transducer of ERBB2, 1 | 0.00628382 |
| PDE10A | phosphodiesterase 10A | 0.00627 |
| INSM1 | insulinoma-associated 1 | 0.00626987 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.00624785 |
| ABHD17A | abhydrolase domain containing 17A | 0.006239 |
| HK2 | hexokinase 2 | 0.00623238 |
| USP13 | ubiquitin specific peptidase 13 (isopeptidase T-3) | 0.00623121 |
| PMM2 | phosphomannomutase 2 | 0.0062302 |
| NXN | nucleoredoxin | 0.00622717 |
| PAX6 | paired box 6 | 0.00618696 |
| ALB | albumin | 0.00618096 |
| GCHFR | GTP cyclohydrolase I feedback regulator | 0.00617241 |
| LOXL1 | lysyl oxidase-like 1 | 0.00615254 |
| CEL | carboxyl ester lipase | 0.00614522 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.00614465 |
| DEPTOR | DEP domain containing MTOR-interacting protein | 0.0061382 |
| POLR2E | polymerase (RNA) II (DNA directed) polypeptide E, 25kDa | 0.00613541 |
| STEAP3 | STEAP family member 3, metalloreductase | 0.00613224 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | 0.0061301 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.00611953 |
| NAV3 | neuron navigator 3 | 0.00610173 |
| INA | internexin neuronal intermediate filament protein, alpha | 0.00606609 |
| KRT7 | keratin 7, type II | 0.006066 |
| RHOBTB1 | Rho-related BTB domain containing 1 | 0.00606483 |
| ZNF91 | zinc finger protein 91 | 0.00606296 |
| DPYD | dihydropyrimidine dehydrogenase | 0.00605663 |
| H2AFV | H2A histone family, member V | 0.00604023 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.00603575 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | 0.00603243 |
| LIMD2 | LIM domain containing 2 | 0.00602668 |
| TGFB1 | transforming growth factor, beta 1 | 0.0060127 |
| CELA3A | chymotrypsin-like elastase family, member 3A | 0.00601218 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.00601069 |
| ANXA10 | annexin A10 | 0.00599379 |
| ESR1 | estrogen receptor 1 | 0.00598835 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | 0.00598074 |
| LRP3 | low density lipoprotein receptor-related protein 3 | 0.00597939 |
| ERCC1 | excision repair cross-complementation group 1 | 0.00597797 |
| GREM1 | gremlin 1, DAN family BMP antagonist | 0.00597488 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 | 0.00596942 |
| IRAG2 | inositol 1,4,5-triphosphate receptor associated 2 | 0.00596563 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.00596544 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | 0.00596408 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.00596395 |
| MBTPS1 | membrane-bound transcription factor peptidase, site 1 | 0.00596338 |
| PDGFRL | platelet-derived growth factor receptor-like | 0.00596177 |
| KLC2 | kinesin light chain 2 | 0.00595997 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | 0.00594442 |
| DACH1 | dachshund family transcription factor 1 | 0.00593504 |
| CLGN | calmegin | 0.00592013 |
| HOXB2 | homeobox B2 | 0.00591606 |
| TLE2 | transducin-like enhancer of split 2 | 0.00591339 |
| TSPO | translocator protein (18kDa) | 0.00591067 |
| PDLIM7 | PDZ and LIM domain 7 (enigma) | 0.00588804 |
| HABP2 | hyaluronan binding protein 2 | 0.00588455 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | 0.00586581 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | 0.00585268 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.00585246 |
| METRN | meteorin, glial cell differentiation regulator | 0.00583166 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | 0.00582915 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 | 0.00582654 |
| COL9A2 | collagen, type IX, alpha 2 | 0.00581046 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 0.00580261 |
| PHYH | phytanoyl-CoA 2-hydroxylase | 0.00579773 |
| H2AX | H2A.X variant histone | 0.00579732 |
| MAMLD1 | mastermind-like domain containing 1 | 0.00579709 |
| CNPY3 | canopy FGF signaling regulator 3 | 0.00579673 |
| PFDN4 | prefoldin subunit 4 | 0.00579598 |
| PLIN1 | perilipin 1 | 0.00576543 |
| CCR2 | chemokine (C-C motif) receptor 2 | 0.00575876 |
| COL6A3 | collagen, type VI, alpha 3 | 0.00575356 |
| KRT19 | keratin 19, type I | 0.00574622 |
| SH3BP4 | SH3-domain binding protein 4 | 0.00574609 |
| SPATA20 | spermatogenesis associated 20 | 0.00574491 |
| VCAN | versican | 0.00573638 |
| SNRPG | small nuclear ribonucleoprotein polypeptide G | 0.00572756 |
| COX17 | COX17 cytochrome c oxidase copper chaperone | 0.0057274 |
| APOB | apolipoprotein B | 0.00569731 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0056957 |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) | 0.00567834 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous | 0.00567325 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AQP3 | aquaporin 3 (Gill blood group) | -0.0215066 |
| LAMP3 | lysosomal-associated membrane protein 3 | -0.0164612 |
| KRT14 | keratin 14, type I | -0.0157672 |
| RNF167 | ring finger protein 167 | -0.0150675 |
| RGCC | regulator of cell cycle | -0.0146068 |
| S100P | S100 calcium binding protein P | -0.0141467 |
| SPRR1B | small proline-rich protein 1B | -0.0137595 |
| TUBB2A | tubulin, beta 2A class IIa | -0.0135767 |
| XPO7 | exportin 7 | -0.0135303 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0133349 |
| TRIM29 | tripartite motif containing 29 | -0.0129645 |
| KRT6A | keratin 6A, type II | -0.0129579 |
| PI3 | peptidase inhibitor 3, skin-derived | -0.0129304 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.012631 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | -0.0126081 |
| KRT5 | keratin 5, type II | -0.0123801 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.0119969 |
| SCEL | sciellin | -0.0118474 |
| TMEM100 | transmembrane protein 100 | -0.0116685 |
| KRT17 | keratin 17, type I | -0.011612 |
| ANXA3 | annexin A3 | -0.0116038 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.0115802 |
| AQP1 | aquaporin 1 (Colton blood group) | -0.0115578 |
| HOPX | HOP homeobox | -0.0113517 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | -0.0111974 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.0110661 |
| TUBB2B | tubulin, beta 2B class IIb | -0.0110636 |
| STOM | stomatin | -0.0108924 |
| LY6D | lymphocyte antigen 6 complex, locus D | -0.0108381 |
| SPRR2B | small proline-rich protein 2B | -0.0107942 |
| KRT1 | keratin 1, type II | -0.0107105 |
| KLK10 | kallikrein-related peptidase 10 | -0.0103767 |
| SYBU | syntabulin (syntaxin-interacting) | -0.0103427 |
| IRS2 | insulin receptor substrate 2 | -0.0102353 |
| SPARCL1 | SPARC-like 1 (hevin) | -0.0102158 |
| IFI44L | interferon-induced protein 44-like | -0.0100242 |
| CA2 | carbonic anhydrase II | -0.0099842 |
| S100A7 | S100 calcium binding protein A7 | -0.00996298 |
| SIRT3 | sirtuin 3 | -0.00996077 |
| CHN1 | chimerin 1 | -0.00990306 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.00984831 |
| GPM6B | glycoprotein M6B | -0.00983499 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.00970378 |
| KRT6B | keratin 6B, type II | -0.00970267 |
| SPRR1A | small proline-rich protein 1A | -0.00965496 |
| HSPA2 | heat shock 70kDa protein 2 | -0.00959224 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.00955379 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | -0.00954216 |
| KRT15 | keratin 15, type I | -0.00953578 |
| SORD | sorbitol dehydrogenase | -0.00948634 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | -0.00946094 |
| DAXX | death-domain associated protein | -0.00943572 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | -0.00942639 |
| PTCH1 | patched 1 | -0.00942302 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.00938083 |
| MCL1 | myeloid cell leukemia 1 | -0.00932784 |
| MXI1 | MAX interactor 1, dimerization protein | -0.00931839 |
| HSPA4L | heat shock 70kDa protein 4-like | -0.00931329 |
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 | -0.0092062 |
| NEBL | nebulette | -0.00920562 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.00916749 |
| HIST1H2AC | histone cluster 1, H2ac | -0.00915879 |
| DSC2 | desmocollin 2 | -0.00904549 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | -0.00903477 |
| MYBPC1 | myosin binding protein C, slow type | -0.00903399 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | -0.00902565 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.00900942 |
| PMP2 | peripheral myelin protein 2 | -0.00897599 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.00893064 |
| ARG1 | arginase 1 | -0.00891555 |
| CLCA2 | chloride channel accessory 2 | -0.0088941 |
| ITM2C | integral membrane protein 2C | -0.0088236 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.00881337 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.00880966 |
| KIFAP3 | kinesin-associated protein 3 | -0.00878502 |
| POU4F1 | POU class 4 homeobox 1 | -0.00876516 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | -0.00871557 |
| RHCG | Rh family, C glycoprotein | -0.00871354 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | -0.00868966 |
| MSMO1 | methylsterol monooxygenase 1 | -0.00866195 |
| GLUL | glutamate-ammonia ligase | -0.00865878 |
| CH25H | cholesterol 25-hydroxylase | -0.00863025 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | -0.00861782 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | -0.00859094 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | -0.0084456 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.00844484 |
| ERGIC2 | ERGIC and golgi 2 | -0.00842655 |
| KRT16 | keratin 16, type I | -0.00839979 |
| ITGA6 | integrin, alpha 6 | -0.00838384 |
| CSRP2 | cysteine and glycine-rich protein 2 | -0.00837494 |
| TRIM22 | tripartite motif containing 22 | -0.00834008 |
| CHI3L2 | chitinase 3-like 2 | -0.00825225 |
| LRP4 | low density lipoprotein receptor-related protein 4 | -0.00825176 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.00823413 |
| CHPT1 | choline phosphotransferase 1 | -0.00821236 |
| ARAP2 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 | -0.00819914 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | -0.00815553 |
| ABLIM1 | actin binding LIM protein 1 | -0.00815043 |
| USP18 | ubiquitin specific peptidase 18 | -0.00812942 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -0.00812062 |
| S100A2 | S100 calcium binding protein A2 | -0.00811615 |
| AQP4 | aquaporin 4 | -0.00810136 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | -0.00809969 |
| DSG3 | desmoglein 3 | -0.00808429 |
| GRAMD2B | GRAM domain containing 2B | -0.00807266 |
| TSPAN3 | tetraspanin 3 | -0.00804779 |
| RALBP1 | ralA binding protein 1 | -0.0079315 |
| DIO2 | deiodinase, iodothyronine, type II | -0.00792093 |
| LAMA3 | laminin, alpha 3 | -0.00790554 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.00786503 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | -0.00785008 |
| MYO1C | myosin IC | -0.00783666 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.00783262 |
| A2M | alpha-2-macroglobulin | -0.00781865 |
| MARF1 | meiosis regulator and mRNA stability factor 1 | -0.00778996 |
| AHCYL1 | adenosylhomocysteinase-like 1 | -0.00777378 |
| EXOC5 | exocyst complex component 5 | -0.00763114 |
| UQCRC2 | ubiquinol-cytochrome c reductase core protein II | -0.00762212 |
| TAL1 | T-cell acute lymphocytic leukemia 1 | -0.00759046 |
| FCGR3B | Fc fragment of IgG, low affinity IIIb, receptor (CD16b) | -0.00757913 |
| DSG1 | desmoglein 1 | -0.00756283 |
| DSP | desmoplakin | -0.00753943 |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) | -0.00753656 |
| RANBP9 | RAN binding protein 9 | -0.00753653 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.00753472 |
| PKP1 | plakophilin 1 | -0.00752777 |
| EDNRB | endothelin receptor type B | -0.00748214 |
| S100A9 | S100 calcium binding protein A9 | -0.00745848 |
| RGS1 | regulator of G-protein signaling 1 | -0.00745458 |
| YIPF6 | Yip1 domain family, member 6 | -0.00743058 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | -0.00742449 |
| LAMC2 | laminin, gamma 2 | -0.00742411 |
| ASXL2 | additional sex combs like transcriptional regulator 2 | -0.00741405 |
| PSAT1 | phosphoserine aminotransferase 1 | -0.00738537 |
| MSX1 | msh homeobox 1 | -0.00737635 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | -0.00736351 |
| NFIL3 | nuclear factor, interleukin 3 regulated | -0.00734926 |
| DCTN4 | dynactin 4 (p62) | -0.00734634 |
| SPRR3 | small proline-rich protein 3 | -0.00732972 |
| ABHD4 | abhydrolase domain containing 4 | -0.00728288 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.00724675 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.00722143 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.00719972 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | -0.0071935 |
| GM2A | GM2 ganglioside activator | -0.00718706 |
| ADAR | adenosine deaminase, RNA-specific | -0.00718438 |
| SLC4A1 | solute carrier family 4 (anion exchanger), member 1 (Diego blood group) | -0.00714646 |
| PPP1R11 | protein phosphatase 1, regulatory (inhibitor) subunit 11 | -0.00713836 |
| KRT13 | keratin 13, type I | -0.00711404 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.00710902 |
| GABARAPL2 | GABA(A) receptor-associated protein-like 2 | -0.00710777 |
| PRAME | preferentially expressed antigen in melanoma | -0.00708039 |
| BTN3A2 | butyrophilin, subfamily 3, member A2 | -0.00707756 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.00707576 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 | -0.00705026 |
| OXTR | oxytocin receptor | -0.00704914 |
| ATP6V1C1 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 | -0.00703813 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | -0.00702512 |
| TOX | thymocyte selection-associated high mobility group box | -0.00700075 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.00698262 |
| EIF5 | eukaryotic translation initiation factor 5 | -0.0069756 |
| TAOK3 | TAO kinase 3 | -0.0069122 |
| IQCG | IQ motif containing G | -0.00690997 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.00690057 |
| XBP1 | X-box binding protein 1 | -0.00688005 |
| SELL | selectin L | -0.00687253 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.00681736 |
| B4GALT4 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 | -0.00678363 |
| GAB2 | GRB2-associated binding protein 2 | -0.00677149 |
| CD53 | CD53 molecule | -0.00676035 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.00674843 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.00673707 |
| CLDND1 | claudin domain containing 1 | -0.0067341 |
| SEC62 | SEC62 homolog (S. cerevisiae) | -0.00671534 |
| PON2 | paraoxonase 2 | -0.0067142 |
| SIAH2 | siah E3 ubiquitin protein ligase 2 | -0.00671118 |
| IL36G | interleukin 36, gamma | -0.00671062 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -0.00668424 |
| LAMP1 | lysosomal-associated membrane protein 1 | -0.0066708 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.00666384 |
| MAPK1 | mitogen-activated protein kinase 1 | -0.00665764 |
| MX1 | MX dynamin-like GTPase 1 | -0.00665254 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | -0.0066418 |
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) | -0.00663217 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.0066316 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | -0.00662006 |
| AMZ2 | archaelysin family metallopeptidase 2 | -0.00660765 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.00658142 |
| CD81 | CD81 molecule | -0.00656755 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | -0.00654685 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 | -0.00654507 |
| CETN2 | centrin, EF-hand protein, 2 | -0.00653821 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.00653416 |
| CSTA | cystatin A (stefin A) | -0.00652164 |
| SLC18A1 | solute carrier family 18 (vesicular monoamine transporter), member 1 | -0.00649808 |
| ESRP1 | epithelial splicing regulatory protein 1 | -0.00649459 |
| UNC13B | unc-13 homolog B (C. elegans) | -0.00649042 |
| S100A12 | S100 calcium binding protein A12 | -0.00646518 |
| BPGM | 2,3-bisphosphoglycerate mutase | -0.00644471 |
| CANX | calnexin | -0.00643875 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.00642979 |
| TFDP1 | transcription factor Dp-1 | -0.00642017 |
| IRF7 | interferon regulatory factor 7 | -0.00640344 |
| GPR171 | G protein-coupled receptor 171 | -0.00639962 |
| TPD52 | tumor protein D52 | -0.00639889 |
| C1QB | complement component 1, q subcomponent, B chain | -0.00638727 |
| F8 | coagulation factor VIII, procoagulant component | -0.0063791 |
| CCL14 | chemokine (C-C motif) ligand 14 | -0.00637572 |
| HHLA3 | HERV-H LTR-associating 3 | -0.00636695 |
| TCF12 | transcription factor 12 | -0.00635013 |
| KLK6 | kallikrein-related peptidase 6 | -0.00634495 |
| HTRA2 | HtrA serine peptidase 2 | -0.0063262 |
| EMC2 | ER membrane protein complex subunit 2 | -0.00632022 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | -0.00631007 |
| KLK8 | kallikrein-related peptidase 8 | -0.00630518 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.0062993 |
| FGFBP1 | fibroblast growth factor binding protein 1 | -0.00629561 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | -0.00628485 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.00627649 |
| NPL | N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) | -0.00626756 |
| ALOX5 | arachidonate 5-lipoxygenase | -0.0062435 |
| MAPK13 | mitogen-activated protein kinase 13 | -0.0062362 |
| FABP7 | fatty acid binding protein 7, brain | -0.00623388 |
| CLIC3 | chloride intracellular channel 3 | -0.00622967 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | -0.00622954 |
| SCRG1 | stimulator of chondrogenesis 1 | -0.00620777 |
| ZNF750 | zinc finger protein 750 | -0.00619668 |
| LHFP | lipoma HMGIC fusion partner | -0.00619491 |
| GSTA4 | glutathione S-transferase alpha 4 | -0.00618771 |
| EGFR | epidermal growth factor receptor | -0.00617025 |
| RRAGA | Ras-related GTP binding A | -0.00614998 |
| CST7 | cystatin F (leukocystatin) | -0.00614777 |
| WASF2 | WAS protein family, member 2 | -0.0061397 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 | -0.00613253 |
| DLD | dihydrolipoamide dehydrogenase | -0.00612642 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.00611697 |
| ZNF267 | zinc finger protein 267 | -0.00611471 |
| RNASET2 | ribonuclease T2 | -0.0061145 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | -0.00610921 |
| C5AR1 | complement component 5a receptor 1 | -0.00610377 |
| ACSL6 | acyl-CoA synthetase long-chain family member 6 | -0.00610296 |
| FGF13 | fibroblast growth factor 13 | -0.00609123 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 | -0.00609075 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | -0.00607605 |
| C8ORF33 | chromosome 8 open reading frame 33 | -0.00605536 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.00604651 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.00604151 |
| ANOS1 | anosmin 1 | -0.00604009 |
| TPBG | trophoblast glycoprotein | -0.0060391 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | -0.00603495 |
