| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | NG25 perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the NG25_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.157017 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.11372 |
| TPM3 | tropomyosin 3 | 0.0937114 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0804232 |
| PCBP2 | poly(rC) binding protein 2 | 0.071614 |
| APP | amyloid beta (A4) precursor protein | 0.0626155 |
| LDHA | lactate dehydrogenase A | 0.0622045 |
| MCL1 | myeloid cell leukemia 1 | 0.059308 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0592597 |
| SEPTIN9 | septin 9 | 0.057736 |
| CD44 | CD44 molecule (Indian blood group) | 0.0575866 |
| CALR | calreticulin | 0.0567877 |
| NDRG1 | N-myc downstream regulated 1 | 0.0546318 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0530751 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0521961 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0515241 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0500286 |
| LOXL2 | lysyl oxidase-like 2 | 0.0489641 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0487563 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.048251 |
| MSN | moesin | 0.0481709 |
| COL3A1 | collagen, type III, alpha 1 | 0.0475979 |
| VIM | vimentin | 0.0468308 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0457399 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.045182 |
| FLNB | filamin B, beta | 0.0441029 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0438011 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0436459 |
| STC1 | stanniocalcin 1 | 0.0435729 |
| FLNA | filamin A, alpha | 0.0414952 |
| B2M | beta-2-microglobulin | 0.0414522 |
| POTEF | POTE ankyrin domain family, member F | 0.0413978 |
| HDAC9 | histone deacetylase 9 | 0.0408233 |
| ADM | adrenomedullin | 0.0400505 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0400013 |
| MYADM | myeloid-associated differentiation marker | 0.0375664 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0374988 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0357871 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0355212 |
| PKM | pyruvate kinase, muscle | 0.0353126 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0336086 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0320766 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0318544 |
| ATP13A3 | ATPase type 13A3 | 0.0318519 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0308551 |
| RPL23 | ribosomal protein L23 | 0.0296461 |
| PLEC | plectin | 0.0293512 |
| ARRDC3 | arrestin domain containing 3 | 0.0291117 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0281688 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0279483 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0274878 |
| RPL3 | ribosomal protein L3 | 0.0274596 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0273909 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0271665 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0270254 |
| PTMA | prothymosin, alpha | 0.0270081 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0269892 |
| SMAD3 | SMAD family member 3 | 0.0267791 |
| SON | SON DNA binding protein | 0.026731 |
| EZR | ezrin | 0.0264741 |
| ENO1 | enolase 1, (alpha) | 0.0262895 |
| C1D | C1D nuclear receptor corepressor | 0.0259344 |
| SQSTM1 | sequestosome 1 | 0.0244033 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0238504 |
| YBX1 | Y box binding protein 1 | 0.023475 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0234147 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0232048 |
| ADAR | adenosine deaminase, RNA-specific | 0.0231294 |
| GPC6 | glypican 6 | 0.0224025 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0223887 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0223846 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0222976 |
| RPS18 | ribosomal protein S18 | 0.0221494 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.0219047 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0217845 |
| ANXA5 | annexin A5 | 0.0216786 |
| UBC | ubiquitin C | 0.0214872 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0212961 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0212683 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0211528 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0210371 |
| HLA-A | major histocompatibility complex, class I, A | 0.0209176 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0207429 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0205825 |
| KLF6 | Kruppel-like factor 6 | 0.0205196 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0197458 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0197413 |
| PPP1R18 | protein phosphatase 1, regulatory subunit 18 | 0.0196756 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0195496 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.019546 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0194784 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0194377 |
| EGR1 | early growth response 1 | 0.0192052 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0191792 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0191567 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0190721 |
| FOSL1 | FOS-like antigen 1 | 0.0190573 |
| MNT | MAX network transcriptional repressor | 0.0189481 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0187848 |
| SET | SET nuclear proto-oncogene | 0.0187366 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.242416 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.20589 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.187331 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.144237 |
| AHNAK | AHNAK nucleoprotein | -0.13311 |
| FN1 | fibronectin 1 | -0.117052 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.107451 |
| LOX | lysyl oxidase | -0.0936624 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0907417 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.088579 |
| CDH13 | cadherin 13 | -0.0722395 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0712151 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0640993 |
| TMSB10 | thymosin beta 10 | -0.0631231 |
| SUCNR1 | succinate receptor 1 | -0.0628429 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.061632 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.05534 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0532202 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0510356 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.05047 |
| COL5A1 | collagen, type V, alpha 1 | -0.0504124 |
| CENPF | centromere protein F, 350/400kDa | -0.0488838 |
| TENM3 | teneurin transmembrane protein 3 | -0.0486757 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0482112 |
| EGFR | epidermal growth factor receptor | -0.0477257 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0463828 |
| CAVIN1 | caveolae associated protein 1 | -0.0442208 |
| CANX | calnexin | -0.0406289 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0401187 |
| DST | dystonin | -0.0379568 |
| FSTL1 | follistatin-like 1 | -0.0378928 |
| S100A10 | S100 calcium binding protein A10 | -0.0378595 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0376499 |
| RIGI | RNA sensor RIG-I | -0.0372583 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0372393 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0369629 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0367916 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0360841 |
| LRRC17 | leucine rich repeat containing 17 | -0.0359903 |
| HLA-B | major histocompatibility complex, class I, B | -0.0358534 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.035439 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0353061 |
| CDK6 | cyclin-dependent kinase 6 | -0.035195 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.0349598 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0344433 |
| PRSS23 | protease, serine, 23 | -0.0342613 |
| THBS2 | thrombospondin 2 | -0.032639 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0325997 |
| DCLK2 | doublecortin-like kinase 2 | -0.0322306 |
| MYOF | myoferlin | -0.0322191 |
| COL5A2 | collagen, type V, alpha 2 | -0.0322136 |
| ACTG1 | actin gamma 1 | -0.0322 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0320467 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0320155 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0312737 |
| S100A4 | S100 calcium binding protein A4 | -0.0311878 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.031028 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0309681 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0304608 |
| INSIG1 | insulin induced gene 1 | -0.0303255 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0296982 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0290974 |
| IL7R | interleukin 7 receptor | -0.0285085 |
| TPM1 | tropomyosin 1 (alpha) | -0.027902 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0274938 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0273835 |
| MEIS2 | Meis homeobox 2 | -0.0268196 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0267947 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0267708 |
| NAV1 | neuron navigator 1 | -0.0267121 |
| FRMD4A | FERM domain containing 4A | -0.0266989 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0266189 |
| RPS24 | ribosomal protein S24 | -0.0258057 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0256551 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0256002 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | -0.0255697 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0254652 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0254646 |
| MMP12 | matrix metallopeptidase 12 | -0.0252423 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.025105 |
| KRT81 | keratin 81, type II | -0.0249556 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0247279 |
| CYTH3 | cytohesin 3 | -0.0243135 |
| ANKUB1 | ankyrin repeat and ubiquitin domain containing 1 | -0.0242541 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | -0.023879 |
| FTL | ferritin, light polypeptide | -0.0238751 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0238701 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0235905 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0235732 |
| NSD3 | nuclear receptor binding SET domain protein 3 | -0.0235608 |
| TNS3 | tensin 3 | -0.0233522 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0231185 |
| CSTB | cystatin B (stefin B) | -0.023022 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0230035 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0227979 |
| SAMD9L | sterile alpha motif domain containing 9-like | -0.0227848 |
| PRELID2 | PRELI domain containing 2 | -0.0226842 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.0226214 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0224434 |
| KRT18 | keratin 18, type I | -0.0223749 |
