| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | NG25 perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the NG25_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AREG | amphiregulin | 0.110872 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0716859 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0426681 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0338838 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0311393 |
| TXNRD1 | thioredoxin reductase 1 | 0.0307941 |
| PCBP2 | poly(rC) binding protein 2 | 0.0299604 |
| YAP1 | Yes-associated protein 1 | 0.0293697 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0292782 |
| RRM2 | ribonucleotide reductase M2 | 0.025268 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0250571 |
| IPO7 | importin 7 | 0.0217948 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0212367 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0193807 |
| WWOX | WW domain containing oxidoreductase | 0.0192735 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0169801 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.016945 |
| EDN1 | endothelin 1 | 0.0156189 |
| HMGA2 | high mobility group AT-hook 2 | 0.0152498 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0150933 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0146177 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | 0.0143999 |
| RPL3 | ribosomal protein L3 | 0.0140238 |
| DENND5A | DENN/MADD domain containing 5A | 0.0134077 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0133306 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0131667 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0129855 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0129013 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0123231 |
| INTS6 | integrator complex subunit 6 | 0.0122449 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0121198 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.0115278 |
| SQSTM1 | sequestosome 1 | 0.0115196 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0115181 |
| TPM3 | tropomyosin 3 | 0.0114535 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0114395 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0113756 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | 0.0113112 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0106654 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0103874 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0103476 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.0100764 |
| RPS18 | ribosomal protein S18 | 0.00991592 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.00991021 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.00973534 |
| MTAP | methylthioadenosine phosphorylase | 0.00972936 |
| ABI2 | abl-interactor 2 | 0.00969364 |
| ARRDC3 | arrestin domain containing 3 | 0.00950105 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.00938737 |
| SACS | sacsin molecular chaperone | 0.00938299 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | 0.00921074 |
| HELLS | helicase, lymphoid-specific | 0.00914075 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.00913313 |
| CD164 | CD164 molecule, sialomucin | 0.00904802 |
| MSH6 | mutS homolog 6 | 0.00900858 |
| ASPH | aspartate beta-hydroxylase | 0.00858872 |
| RAD51B | RAD51 paralog B | 0.00858045 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.00842831 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | 0.00834117 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0082591 |
| NSD3 | nuclear receptor binding SET domain protein 3 | 0.00811134 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.00806443 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.00806153 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.00799022 |
| ETNK1 | ethanolamine kinase 1 | 0.00792141 |
| APTX | aprataxin | 0.00790702 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.00789776 |
| UBC | ubiquitin C | 0.00789199 |
| MCL1 | myeloid cell leukemia 1 | 0.00786263 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.00774662 |
| CSMD1 | CUB and Sushi multiple domains 1 | 0.00764549 |
| MACROH2A1 | macroH2A.1 histone | 0.00753269 |
| ICAM1 | intercellular adhesion molecule 1 | 0.00750796 |
| RBBP7 | retinoblastoma binding protein 7 | 0.00745118 |
| PAX6 | paired box 6 | 0.00744486 |
| MAT2A | methionine adenosyltransferase II, alpha | 0.0074122 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.00740681 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.00730586 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.00725895 |
| ALMS1 | Alstrom syndrome protein 1 | 0.00722698 |
| QSER1 | glutamine and serine rich 1 | 0.00715826 |
| FHIT | fragile histidine triad | 0.00714613 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | 0.00711573 |
| ALG13 | ALG13, UDP-N-acetylglucosaminyltransferase subunit | 0.00711352 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 0.00709579 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.00702171 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.00691459 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.00689348 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.00689236 |
| FANCI | Fanconi anemia, complementation group I | 0.00686397 |
| CCNL1 | cyclin L1 | 0.00684213 |
| CLPTM1L | CLPTM1-like | 0.00683315 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | 0.00681818 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.00679521 |
| CCDC200 | coiled-coil domain containing 200 | 0.00679162 |
| HOMER1 | homer scaffolding protein 1 | 0.00675632 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.00672995 |
| HELB | helicase (DNA) B | 0.00670747 |
| SMAP1 | small ArfGAP 1 | 0.00669744 |
| DIAPH3 | diaphanous-related formin 3 | 0.00660105 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.17387 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.12694 |
| NLGN1 | neuroligin 1 | -0.0892158 |
| TMSB10 | thymosin beta 10 | -0.0823616 |
| FTL | ferritin, light polypeptide | -0.0685907 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.067434 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0604923 |
| PTMA | prothymosin, alpha | -0.0573117 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0550573 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0509362 |
| RPL35A | ribosomal protein L35a | -0.0468523 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0439335 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0429012 |
| VIM | vimentin | -0.0427888 |
| MMP12 | matrix metallopeptidase 12 | -0.0424239 |
| RPS3 | ribosomal protein S3 | -0.0411014 |
| ACTG1 | actin gamma 1 | -0.0401337 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0393004 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0380368 |
| ZNF804A | zinc finger protein 804A | -0.0374021 |
| RPL37A | ribosomal protein L37a | -0.0373999 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0370611 |
| CENPF | centromere protein F, 350/400kDa | -0.0369471 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0368607 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0360481 |
| RPS8 | ribosomal protein S8 | -0.0349011 |
| RPL23 | ribosomal protein L23 | -0.0330384 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0328834 |
| RPL26 | ribosomal protein L26 | -0.0328212 |
| MGAT4C | MGAT4 family, member C | -0.0325017 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0318563 |
| RPS12 | ribosomal protein S12 | -0.0307721 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0305045 |
| RPS6 | ribosomal protein S6 | -0.0296545 |
| PFN1 | profilin 1 | -0.0287633 |
| ANXA1 | annexin A1 | -0.0285377 |
| DST | dystonin | -0.0274805 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0267913 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.026597 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0263684 |
| RPS27A | ribosomal protein S27a | -0.0263154 |
| BCHE | butyrylcholinesterase | -0.0262119 |
| CDK6 | cyclin-dependent kinase 6 | -0.0257085 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0256125 |
| CALR | calreticulin | -0.0255561 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.0254644 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0251362 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.0250388 |
| SYT1 | synaptotagmin I | -0.0245305 |
| RPLP1 | ribosomal protein, large, P1 | -0.0240711 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0238709 |
| RPL11 | ribosomal protein L11 | -0.0238457 |
| RPL8 | ribosomal protein L8 | -0.0234927 |
| EHBP1 | EH domain binding protein 1 | -0.0234623 |
| RPL19 | ribosomal protein L19 | -0.023226 |
| LDHB | lactate dehydrogenase B | -0.0228996 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0226186 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0225437 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0223258 |
| RASAL2 | RAS protein activator like 2 | -0.0220761 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0219653 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0219356 |
| CANX | calnexin | -0.0217175 |
| S100A6 | S100 calcium binding protein A6 | -0.021551 |
| PTMS | parathymosin | -0.0211157 |
| EGR1 | early growth response 1 | -0.0206753 |
| TPI1 | triosephosphate isomerase 1 | -0.0206377 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0206368 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.020179 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | -0.0201461 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | -0.0201262 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.0200477 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0198082 |
| FSTL5 | follistatin-like 5 | -0.0197879 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0196034 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0193724 |
| RPL34 | ribosomal protein L34 | -0.0193018 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0192323 |
| RPS21 | ribosomal protein S21 | -0.0191874 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0189312 |
| RPS29 | ribosomal protein S29 | -0.0188545 |
| RPS14 | ribosomal protein S14 | -0.0187564 |
| RPLP2 | ribosomal protein, large, P2 | -0.018458 |
| RPL37 | ribosomal protein L37 | -0.0184529 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0182646 |
| FBXO11 | F-box protein 11 | -0.0182403 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0182299 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0181157 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0180198 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0180127 |
| LMO7 | LIM domain 7 | -0.0180065 |
| RHOA | ras homolog family member A | -0.0176415 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0174028 |
| HDGF | hepatoma-derived growth factor | -0.0173139 |
| GOLGA4 | golgin A4 | -0.0171378 |
| RPS13 | ribosomal protein S13 | -0.0170364 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0168658 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0168393 |
| HSPE1 | heat shock 10kDa protein 1 | -0.0167677 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0165716 |
