| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | NG25 perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the NG25_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.357254 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.116397 |
| PCBP2 | poly(rC) binding protein 2 | 0.0830612 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0807033 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0695367 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0562684 |
| DPH6 | diphthamine biosynthesis 6 | 0.048921 |
| MAP1B | microtubule-associated protein 1B | 0.0485193 |
| MCL1 | myeloid cell leukemia 1 | 0.0454253 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0436037 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | 0.0423241 |
| DST | dystonin | 0.0401598 |
| RPL23 | ribosomal protein L23 | 0.0387114 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0386524 |
| TLE4 | transducin-like enhancer of split 4 | 0.0372737 |
| MEF2A | myocyte enhancer factor 2A | 0.0366159 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0346007 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0335597 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0334776 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0329544 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0325343 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | 0.0318236 |
| VEGFA | vascular endothelial growth factor A | 0.0312531 |
| RPL3 | ribosomal protein L3 | 0.0311202 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0308658 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.029444 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0293586 |
| RUNX1 | runt-related transcription factor 1 | 0.0292412 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0285785 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0283524 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0281743 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0279489 |
| DNMBP | dynamin binding protein | 0.02779 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0276091 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.027266 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0268589 |
| LPIN1 | lipin 1 | 0.0267799 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0265793 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0256028 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0255076 |
| MMP2 | matrix metallopeptidase 2 | 0.0253734 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0247113 |
| PLPP1 | phospholipid phosphatase 1 | 0.0240907 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.0239854 |
| PLAT | plasminogen activator, tissue | 0.0236721 |
| RPS18 | ribosomal protein S18 | 0.0230213 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0228399 |
| SEPTIN9 | septin 9 | 0.0227277 |
| DGKH | diacylglycerol kinase, eta | 0.0223859 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0216494 |
| APP | amyloid beta (A4) precursor protein | 0.0215355 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0213653 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0212787 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0212098 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0211869 |
| RET | ret proto-oncogene | 0.0211383 |
| ANGPTL4 | angiopoietin-like 4 | 0.021083 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0208 |
| ZNF148 | zinc finger protein 148 | 0.0206882 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0203925 |
| HELZ | helicase with zinc finger | 0.0203699 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0195831 |
| RNF145 | ring finger protein 145 | 0.019483 |
| POTEF | POTE ankyrin domain family, member F | 0.0190905 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0186557 |
| TXNIP | thioredoxin interacting protein | 0.0186167 |
| MATR3 | matrin 3 | 0.0185584 |
| FERMT2 | fermitin family member 2 | 0.0185347 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.0184821 |
| ACTN1 | actinin, alpha 1 | 0.0179478 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0179226 |
| ADAR | adenosine deaminase, RNA-specific | 0.0177282 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0176305 |
| CSNK1D | casein kinase 1, delta | 0.0175776 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0174927 |
| SEPTIN7 | septin 7 | 0.0173798 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0173387 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0172714 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0171978 |
| RAB30 | RAB30, member RAS oncogene family | 0.017044 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.0170422 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0169347 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0168924 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0168895 |
| AAK1 | AP2 associated kinase 1 | 0.0165487 |
| PDE8A | phosphodiesterase 8A | 0.0164781 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0164292 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0164287 |
| KCTD3 | potassium channel tetramerization domain containing 3 | 0.0163626 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0163208 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0163019 |
| SQSTM1 | sequestosome 1 | 0.016268 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | 0.016239 |
| CCDC57 | coiled-coil domain containing 57 | 0.016124 |
| RPL27 | ribosomal protein L27 | 0.0160719 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0160599 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0159551 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0158389 |
| ENAH | enabled homolog (Drosophila) | 0.0157758 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0156147 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.319632 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.175596 |
| LSAMP | limbic system-associated membrane protein | -0.127957 |
| NRG1 | neuregulin 1 | -0.0935922 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0798301 |
| COL1A1 | collagen, type I, alpha 1 | -0.0611442 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0589713 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0574455 |
| RPS24 | ribosomal protein S24 | -0.0555175 |
| CRH | corticotropin releasing hormone | -0.0486305 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0438605 |
| BPTF | bromodomain PHD finger transcription factor | -0.0410206 |
| ACTG1 | actin gamma 1 | -0.040067 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0395174 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0394803 |
| RPL35A | ribosomal protein L35a | -0.0390363 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0389169 |
| CENPF | centromere protein F, 350/400kDa | -0.0383201 |
| ZNF804A | zinc finger protein 804A | -0.0372964 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0357492 |
| PTMA | prothymosin, alpha | -0.0351018 |
| PDZRN3 | PDZ domain containing ring finger 3 | -0.0341782 |
| NREP | neuronal regeneration related protein | -0.0329827 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0328197 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0314914 |
| PARD3 | par-3 family cell polarity regulator | -0.0311135 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0287517 |
| RPL38 | ribosomal protein L38 | -0.0277082 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.027475 |
| COL3A1 | collagen, type III, alpha 1 | -0.0269874 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0268518 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0260178 |
| TMSB10 | thymosin beta 10 | -0.0259439 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0246157 |
| TULP4 | tubby like protein 4 | -0.0235101 |
| PRKCA | protein kinase C, alpha | -0.0233322 |
| CUX1 | cut-like homeobox 1 | -0.023027 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0226607 |
| CNTN4 | contactin 4 | -0.0225882 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0225354 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0225253 |
| PCDH9 | protocadherin 9 | -0.0223408 |
| H3-3B | H3.3 histone B | -0.0219318 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0218961 |
| ATXN10 | ataxin 10 | -0.0215824 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0213817 |
| RPL26 | ribosomal protein L26 | -0.0212032 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0211952 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0211287 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.021112 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0209249 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0208265 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0207191 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.020576 |
| RPL7A | ribosomal protein L7a | -0.0205585 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0203015 |
| EGR1 | early growth response 1 | -0.020017 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0198515 |
| PCNP | PEST proteolytic signal containing nuclear protein | -0.0195408 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0194815 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0192873 |
| HMGB1 | high mobility group box 1 | -0.0192494 |
| PCDH11Y | protocadherin 11 Y-linked | -0.0191597 |
| RPS16 | ribosomal protein S16 | -0.0188991 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.018859 |
| PCNX4 | pecanex 4 | -0.0187955 |
| HIP1 | huntingtin interacting protein 1 | -0.0187618 |
| RPL19 | ribosomal protein L19 | -0.0185826 |
| FTL | ferritin, light polypeptide | -0.0185672 |
| HMGB2 | high mobility group box 2 | -0.0184219 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0183957 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0182819 |
| PRR11 | proline rich 11 | -0.0182513 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0182136 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.018185 |
| ABI2 | abl-interactor 2 | -0.0179228 |
| NUP214 | nucleoporin 214kDa | -0.0178775 |
| CDH13 | cadherin 13 | -0.0177921 |
| RPS21 | ribosomal protein S21 | -0.0177226 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0176238 |
| IER3 | immediate early response 3 | -0.0175818 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0175758 |
| MED13 | mediator complex subunit 13 | -0.0175561 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0174792 |
| THOC2 | THO complex 2 | -0.0173224 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0172892 |
| RPS27A | ribosomal protein S27a | -0.0172384 |
| ZNF33A | zinc finger protein 33A | -0.0171234 |
| CCDC47 | coiled-coil domain containing 47 | -0.0170395 |
| HLA-B | major histocompatibility complex, class I, B | -0.0170244 |
| RALYL | RALY RNA binding protein-like | -0.0169886 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.016819 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0167461 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0167419 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0166087 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0166057 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0166025 |
| DKK2 | dickkopf WNT signaling pathway inhibitor 2 | -0.016577 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0164642 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0163741 |
