| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | NG25 perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the NG25_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.188431 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.127563 |
| EXT1 | exostosin glycosyltransferase 1 | 0.121185 |
| B2M | beta-2-microglobulin | 0.103811 |
| LCN2 | lipocalin 2 | 0.0963913 |
| SMAD3 | SMAD family member 3 | 0.0887019 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0813779 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.075831 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0718516 |
| RNF213 | ring finger protein 213 | 0.0700832 |
| TJP1 | tight junction protein 1 | 0.0625542 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0592638 |
| MYO1E | myosin IE | 0.056852 |
| ASPH | aspartate beta-hydroxylase | 0.0565005 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0540435 |
| INTS6 | integrator complex subunit 6 | 0.0528645 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.05277 |
| TMC5 | transmembrane channel-like 5 | 0.0525447 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0519669 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0516824 |
| ETV6 | ets variant 6 | 0.0512311 |
| VCL | vinculin | 0.0508977 |
| EFNB2 | ephrin-B2 | 0.0466834 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0453605 |
| C6ORF132 | chromosome 6 open reading frame 132 | 0.0420429 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0416601 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0408344 |
| MAP7 | microtubule-associated protein 7 | 0.0399758 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0399548 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0399188 |
| VMP1 | vacuole membrane protein 1 | 0.0398746 |
| AREG | amphiregulin | 0.0396829 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0394207 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.0386406 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0385604 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0381529 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0381492 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0375561 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0374169 |
| ERBIN | erbb2 interacting protein | 0.0372782 |
| FAT1 | FAT atypical cadherin 1 | 0.0371471 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0367196 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0362984 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0362376 |
| MYO5B | myosin VB | 0.0361899 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0355537 |
| TXNIP | thioredoxin interacting protein | 0.0355411 |
| HKDC1 | hexokinase domain containing 1 | 0.0349736 |
| LIMA1 | LIM domain and actin binding 1 | 0.034708 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0340414 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0336022 |
| RUNX1 | runt-related transcription factor 1 | 0.0333136 |
| STK24 | serine/threonine kinase 24 | 0.0328389 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0327719 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0324899 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.032373 |
| HLA-B | major histocompatibility complex, class I, B | 0.0315967 |
| ANXA2 | annexin A2 | 0.0315075 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0312308 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0311906 |
| MSI2 | musashi RNA-binding protein 2 | 0.0310431 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.030716 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0302945 |
| RBM47 | RNA binding motif protein 47 | 0.0301646 |
| YAP1 | Yes-associated protein 1 | 0.0299779 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0299254 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0298753 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.0295249 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0289488 |
| SEPTIN9 | septin 9 | 0.0287315 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0285001 |
| DIAPH1 | diaphanous-related formin 1 | 0.0282017 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0281461 |
| KYNU | kynureninase | 0.0280542 |
| IFNGR1 | interferon gamma receptor 1 | 0.0274964 |
| PRKCA | protein kinase C, alpha | 0.0274459 |
| PDZD8 | PDZ domain containing 8 | 0.0271814 |
| SPAG9 | sperm associated antigen 9 | 0.0269831 |
| DUSP10 | dual specificity phosphatase 10 | 0.0265652 |
| ATP11A | ATPase, class VI, type 11A | 0.0263647 |
| EREG | epiregulin | 0.0261843 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0255452 |
| FHL2 | four and a half LIM domains 2 | 0.0253713 |
| KLF6 | Kruppel-like factor 6 | 0.0249318 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0246633 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0241759 |
| SIK3 | SIK family kinase 3 | 0.0241007 |
| PKM | pyruvate kinase, muscle | 0.0239076 |
| CLDN4 | claudin 4 | 0.0238866 |
| MCU | mitochondrial calcium uniporter | 0.0238048 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0236457 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0235001 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0233587 |
| NCKAP5 | NCK-associated protein 5 | 0.0233193 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0232044 |
| SP100 | SP100 nuclear antigen | 0.0231525 |
| MX1 | MX dynamin-like GTPase 1 | 0.0230349 |
| RAD51B | RAD51 paralog B | 0.0229469 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0229412 |
| MED13 | mediator complex subunit 13 | 0.0226086 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.300271 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0816132 |
| FTL | ferritin, light polypeptide | -0.0690857 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0597047 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0532434 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0503246 |
| NDRG1 | N-myc downstream regulated 1 | -0.0384764 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.037569 |
| NPSR1 | neuropeptide S receptor 1 | -0.0317892 |
| RPL9 | ribosomal protein L9 | -0.0298633 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0251246 |
| RPS12 | ribosomal protein S12 | -0.0248178 |
| ABHD2 | abhydrolase domain containing 2 | -0.0245983 |
| THOC2 | THO complex 2 | -0.0244374 |
| LYZ | lysozyme | -0.0243709 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0234202 |
| SERINC5 | serine incorporator 5 | -0.0233491 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0222233 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0218107 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0210824 |
| RPS3 | ribosomal protein S3 | -0.0208864 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0208473 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.0208398 |
| CANX | calnexin | -0.0204355 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.019705 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0193516 |
| OGA | O-GlcNAcase | -0.0189397 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0187716 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0186178 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0184449 |
| PTGR1 | prostaglandin reductase 1 | -0.0184328 |
| RBM26 | RNA binding motif protein 26 | -0.0181733 |
| RNF43 | ring finger protein 43 | -0.0181648 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0176644 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0174426 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0170211 |
| PATJ | PATJ crumbs cell polarity complex component | -0.016626 |
| RPL34 | ribosomal protein L34 | -0.0164616 |
| RPL37A | ribosomal protein L37a | -0.0161731 |
| SUGT1 | SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae) | -0.0161402 |
| RPL26 | ribosomal protein L26 | -0.0160857 |
| RPS6 | ribosomal protein S6 | -0.0159327 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.015884 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0153001 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0152577 |
| RPL35A | ribosomal protein L35a | -0.0145572 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0144804 |
| H1-0 | H1.0 linker histone | -0.0142427 |
| TPR | translocated promoter region, nuclear basket protein | -0.014175 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | -0.0140194 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0138374 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0137242 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0135547 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.0135423 |
| CHD6 | chromodomain helicase DNA binding protein 6 | -0.0134238 |
| RACK1 | receptor for activated C kinase 1 | -0.013261 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.0132237 |
| HSPE1 | heat shock 10kDa protein 1 | -0.0131988 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.013169 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.013164 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0131159 |
| MUC20 | mucin 20, cell surface associated | -0.0129551 |
| DYNC2I1 | dynein 2 intermediate chain 1 | -0.0128213 |
| UBAC2 | UBA domain containing 2 | -0.0125912 |
| GBP2 | guanylate binding protein 2, interferon-inducible | -0.0124824 |
| SBF2 | SET binding factor 2 | -0.0122909 |
| RPL13A | ribosomal protein L13a | -0.0122771 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0122743 |
| PTMA | prothymosin, alpha | -0.0121901 |
| CSTPP1 | centriolar satellite-associated tubulin polyglutamylase complex regulator 1 | -0.0121896 |
| PTEN | phosphatase and tensin homolog | -0.0120825 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0120217 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0120182 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0119936 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0119906 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0119631 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | -0.0119282 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0118723 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0118529 |
| LASP1 | LIM and SH3 protein 1 | -0.0118175 |
| GOLGB1 | golgin B1 | -0.0118007 |
| SECISBP2L | SECIS binding protein 2-like | -0.0117907 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0117638 |
| RPS29 | ribosomal protein S29 | -0.0117574 |
| RPL23 | ribosomal protein L23 | -0.0117026 |
| ZBTB44 | zinc finger and BTB domain containing 44 | -0.0114921 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0114035 |
| TAOK3 | TAO kinase 3 | -0.0113421 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0111001 |
| RPS27 | ribosomal protein S27 | -0.0110768 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0110726 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0110033 |
| CIRSR | corepressor of RBPJ and splicing regulator | -0.0109766 |
| TMEM87A | transmembrane protein 87A | -0.0109517 |
| CTSD | cathepsin D | -0.0107871 |
| USP47 | ubiquitin specific peptidase 47 | -0.0107167 |
| ACTG1 | actin gamma 1 | -0.0107112 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0107045 |
| RPS25 | ribosomal protein S25 | -0.0107015 |
| HBS1L | HBS1-like translational GTPase | -0.010696 |
