| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | NG25 perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the NG25_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.27842 |
| IGFBP1 | insulin-like growth factor binding protein 1 | 0.120514 |
| SVIL | supervillin | 0.102543 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0852721 |
| PDLIM5 | PDZ and LIM domain 5 | 0.081873 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0772411 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0753831 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0734548 |
| ENO1 | enolase 1, (alpha) | 0.0701052 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0699277 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0681549 |
| ASPH | aspartate beta-hydroxylase | 0.0620454 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0596399 |
| FAM107B | family with sequence similarity 107, member B | 0.0557006 |
| ATXN1 | ataxin 1 | 0.0528896 |
| RPS18 | ribosomal protein S18 | 0.0477581 |
| MT2A | metallothionein 2A | 0.0476886 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0463898 |
| INTS6 | integrator complex subunit 6 | 0.0440475 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0440195 |
| FAT1 | FAT atypical cadherin 1 | 0.0437101 |
| MCL1 | myeloid cell leukemia 1 | 0.0435905 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0431822 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0407566 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0400744 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0393845 |
| KYNU | kynureninase | 0.0384771 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0361717 |
| HMGA1 | high mobility group AT-hook 1 | 0.0356044 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.0355776 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0354543 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0353242 |
| RPL3 | ribosomal protein L3 | 0.0352049 |
| DSPP | dentin sialophosphoprotein | 0.0339051 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0310308 |
| POTEF | POTE ankyrin domain family, member F | 0.0295653 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0284847 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0281557 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0280955 |
| SMAD3 | SMAD family member 3 | 0.0274179 |
| DTNA | dystrobrevin, alpha | 0.0273476 |
| PCBP2 | poly(rC) binding protein 2 | 0.0266816 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0265684 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0258596 |
| FRMD5 | FERM domain containing 5 | 0.0257169 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0253266 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0252515 |
| RPS12 | ribosomal protein S12 | 0.0249906 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.0238837 |
| HPCAL1 | hippocalcin-like 1 | 0.0235141 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.023203 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0224421 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0223312 |
| MYO5B | myosin VB | 0.0214532 |
| CANX | calnexin | 0.0213828 |
| FERMT2 | fermitin family member 2 | 0.0213174 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0213008 |
| RPS17 | ribosomal protein S17 | 0.0209667 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0208161 |
| TNS1 | tensin 1 | 0.0207014 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0206855 |
| TPM3 | tropomyosin 3 | 0.0205663 |
| DIAPH1 | diaphanous-related formin 1 | 0.020545 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0204561 |
| PLEC | plectin | 0.020335 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0200587 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 | 0.0200275 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.019919 |
| STC2 | stanniocalcin 2 | 0.0198475 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0198448 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | 0.0197791 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0197565 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0197388 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0196461 |
| ITGA6 | integrin, alpha 6 | 0.0195628 |
| RPS7 | ribosomal protein S7 | 0.0195052 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0194778 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0192643 |
| TLE4 | transducin-like enhancer of split 4 | 0.0191503 |
| KRT8 | keratin 8, type II | 0.019093 |
| MYO1E | myosin IE | 0.0190858 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0190388 |
| RAD51B | RAD51 paralog B | 0.0188395 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0187501 |
| HM13 | histocompatibility (minor) 13 | 0.0186756 |
| PLIN2 | perilipin 2 | 0.0186079 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0185345 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0184424 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.0182572 |
| PGM3 | phosphoglucomutase 3 | 0.0181456 |
| DUSP16 | dual specificity phosphatase 16 | 0.0180904 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0179284 |
| RASA2 | RAS p21 protein activator 2 | 0.0178509 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0178395 |
| MTSS1 | metastasis suppressor 1 | 0.0176859 |
| RAI14 | retinoic acid induced 14 | 0.0175847 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0175161 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.017403 |
| SQSTM1 | sequestosome 1 | 0.0173601 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | 0.0171419 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.33249 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.195136 |
| APOB | apolipoprotein B | -0.164848 |
| APOA2 | apolipoprotein A-II | -0.132056 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.091183 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0888449 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.0860095 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0785191 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0759078 |
| FN1 | fibronectin 1 | -0.0720658 |
| GPC3 | glypican 3 | -0.0720156 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.067229 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0667047 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | -0.0652 |
| TRIM26 | tripartite motif containing 26 | -0.0650887 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0622218 |
| TMEM123 | transmembrane protein 123 | -0.059729 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0590008 |
| A2M | alpha-2-macroglobulin | -0.058752 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0565805 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0563444 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.054315 |
| FTL | ferritin, light polypeptide | -0.0500823 |
| PEG10 | paternally expressed 10 | -0.0497037 |
| RBM39 | RNA binding motif protein 39 | -0.048875 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0475387 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0452872 |
| LYZ | lysozyme | -0.0431828 |
| JMJD1C | jumonji domain containing 1C | -0.0411691 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0407593 |
| RPS6 | ribosomal protein S6 | -0.0405615 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.0404033 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | -0.039746 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0393477 |
| PEG3 | paternally expressed 3 | -0.0392324 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0385776 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0383555 |
| CP | ceruloplasmin (ferroxidase) | -0.0382931 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0378588 |
| RBM25 | RNA binding motif protein 25 | -0.0359948 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.0358723 |
| RPS24 | ribosomal protein S24 | -0.0355454 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.03523 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0351274 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0351145 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0327387 |
| SELENOP | selenoprotein P | -0.0327333 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0327049 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0320502 |
| PDGFB | platelet-derived growth factor beta polypeptide | -0.0320171 |
| RPL11 | ribosomal protein L11 | -0.0317241 |
| RPLP0 | ribosomal protein, large, P0 | -0.0316084 |
| APOH | apolipoprotein H (beta-2-glycoprotein I) | -0.0313801 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 | -0.0313222 |
| APOE | apolipoprotein E | -0.0311909 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0309945 |
| RPL35A | ribosomal protein L35a | -0.030966 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0308543 |
| PHYHIPL | phytanoyl-CoA 2-hydroxylase interacting protein-like | -0.0307292 |
| MALT1 | MALT1 paracaspase | -0.030722 |
| PERP | PERP, TP53 apoptosis effector | -0.0304382 |
| MBNL3 | muscleblind-like splicing regulator 3 | -0.0292212 |
| DENND4A | DENN/MADD domain containing 4A | -0.0289205 |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) | -0.0288186 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0283951 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0283877 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | -0.0283265 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0283006 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0280326 |
| NPR2 | natriuretic peptide receptor 2 | -0.0280253 |
| PHF21A | PHD finger protein 21A | -0.0277527 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0277119 |
| ITGA1 | integrin, alpha 1 | -0.0276085 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0275944 |
| CFB | complement factor B | -0.0274151 |
| RRBP1 | ribosome binding protein 1 | -0.0272287 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0271281 |
| PRRC2C | proline-rich coiled-coil 2C | -0.027105 |
| SESTD1 | SEC14 and spectrin domains 1 | -0.0271018 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.027066 |
| H1-0 | H1.0 linker histone | -0.026982 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0269091 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0268118 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | -0.026674 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0265997 |
| PTCHD4 | patched domain containing 4 | -0.0262682 |
| RPS21 | ribosomal protein S21 | -0.0252754 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0251171 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0250774 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0243294 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0242314 |
| PEBP1 | phosphatidylethanolamine binding protein 1 | -0.0240726 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.023998 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0238377 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0235515 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0234729 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0231142 |
| KIF5B | kinesin family member 5B | -0.0230366 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0229076 |
| CST3 | cystatin C | -0.022824 |
