| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | NG25 perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the NG25_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.116759 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.102166 |
| PTMA | prothymosin, alpha | 0.100786 |
| FAT1 | FAT atypical cadherin 1 | 0.0991541 |
| EZR | ezrin | 0.0933151 |
| LMO7 | LIM domain 7 | 0.0878124 |
| ASPH | aspartate beta-hydroxylase | 0.077185 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0699926 |
| TXNIP | thioredoxin interacting protein | 0.0606713 |
| MT2A | metallothionein 2A | 0.0551882 |
| LDHA | lactate dehydrogenase A | 0.0549037 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0539461 |
| EXT1 | exostosin glycosyltransferase 1 | 0.053654 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0495939 |
| VEGFA | vascular endothelial growth factor A | 0.0489969 |
| MYO1E | myosin IE | 0.0489772 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0456652 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0454473 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0440094 |
| PCBP2 | poly(rC) binding protein 2 | 0.042653 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0402597 |
| AREG | amphiregulin | 0.039947 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0385599 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0385187 |
| TPM4 | tropomyosin 4 | 0.0377003 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0376559 |
| MED13 | mediator complex subunit 13 | 0.0375978 |
| RPL3 | ribosomal protein L3 | 0.0369045 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0366806 |
| EMP1 | epithelial membrane protein 1 | 0.0364682 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0349547 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0343077 |
| TPM3 | tropomyosin 3 | 0.0339256 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0336816 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0335328 |
| CALR | calreticulin | 0.0334485 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0333595 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0330137 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0326624 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0326402 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.0323559 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0316754 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0312858 |
| POTEF | POTE ankyrin domain family, member F | 0.0310832 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0310549 |
| EGFR | epidermal growth factor receptor | 0.030945 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0303849 |
| EREG | epiregulin | 0.03037 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0300198 |
| RPS18 | ribosomal protein S18 | 0.0299852 |
| MCL1 | myeloid cell leukemia 1 | 0.0299761 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0295208 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0292497 |
| ANXA1 | annexin A1 | 0.0290076 |
| ITGA6 | integrin, alpha 6 | 0.0277256 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0275065 |
| NDRG1 | N-myc downstream regulated 1 | 0.0271269 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0269345 |
| LAMA4 | laminin, alpha 4 | 0.0268896 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0268447 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.0266224 |
| UNC13B | unc-13 homolog B (C. elegans) | 0.0261203 |
| WHRN | whirlin | 0.0259575 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0256576 |
| MYO5B | myosin VB | 0.0250868 |
| TES | testin LIM domain protein | 0.0250619 |
| MUC17 | mucin 17, cell surface associated | 0.0248752 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0246591 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0240056 |
| TFF1 | trefoil factor 1 | 0.0237044 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0235421 |
| LMNA | lamin A/C | 0.0235108 |
| USP6NL | USP6 N-terminal like | 0.0234437 |
| SIK3 | SIK family kinase 3 | 0.0231185 |
| CLCN3 | chloride channel, voltage-sensitive 3 | 0.0228297 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.022626 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0226095 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0225428 |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta | 0.0224621 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | 0.0222892 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | 0.0222297 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0222137 |
| KLF6 | Kruppel-like factor 6 | 0.0220942 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0218809 |
| CRY1 | cryptochrome circadian clock 1 | 0.0218407 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0218346 |
| SQSTM1 | sequestosome 1 | 0.0216332 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0215847 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0214582 |
| CLDN4 | claudin 4 | 0.0211698 |
| RCOR1 | REST corepressor 1 | 0.0211269 |
| PARD3 | par-3 family cell polarity regulator | 0.0209067 |
| TJP1 | tight junction protein 1 | 0.0208947 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0205014 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0204301 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0203249 |
| PKM | pyruvate kinase, muscle | 0.0201489 |
| RORA | RAR-related orphan receptor A | 0.0201404 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0201261 |
| JUN | jun proto-oncogene | 0.0200826 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.168524 |
| NPSR1 | neuropeptide S receptor 1 | -0.127795 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0897839 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.082999 |
| GPHN | gephyrin | -0.0829799 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0770725 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0613035 |
| RPL35A | ribosomal protein L35a | -0.0562568 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0523825 |
| RNF43 | ring finger protein 43 | -0.049671 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.048635 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0476237 |
| TNS4 | tensin 4 | -0.0470713 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0452523 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0431555 |
| RPS6 | ribosomal protein S6 | -0.042943 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0428372 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0423248 |
| FHIT | fragile histidine triad | -0.0417869 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0408668 |
| EPCAM | epithelial cell adhesion molecule | -0.0404752 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0397548 |
| VCL | vinculin | -0.0372785 |
| RPLP2 | ribosomal protein, large, P2 | -0.0370845 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0368281 |
| NRXN3 | neurexin 3 | -0.0355801 |
| MECOM | MDS1 and EVI1 complex locus | -0.03471 |
| RPL34 | ribosomal protein L34 | -0.0341332 |
| RPS24 | ribosomal protein S24 | -0.0339266 |
| TMSB10 | thymosin beta 10 | -0.0334471 |
| RPL11 | ribosomal protein L11 | -0.032988 |
| RPL36 | ribosomal protein L36 | -0.0327819 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0327145 |
| RPL23 | ribosomal protein L23 | -0.0326696 |
| RPLP1 | ribosomal protein, large, P1 | -0.0322851 |
| RPS19 | ribosomal protein S19 | -0.0321635 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0321391 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0307989 |
| RPL13A | ribosomal protein L13a | -0.0303083 |
| H1-0 | H1.0 linker histone | -0.030282 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0299082 |
| FOXP1 | forkhead box P1 | -0.0298855 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0294949 |
| RPS29 | ribosomal protein S29 | -0.029466 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0293654 |
| AHNAK | AHNAK nucleoprotein | -0.0289816 |
| RBM39 | RNA binding motif protein 39 | -0.0287518 |
| RPL9 | ribosomal protein L9 | -0.0286936 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0285713 |
| PIGR | polymeric immunoglobulin receptor | -0.0283466 |
| RPL5 | ribosomal protein L5 | -0.0282338 |
| NFIA | nuclear factor I/A | -0.0280934 |
| RPS21 | ribosomal protein S21 | -0.0278682 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | -0.0276316 |
| RPL37A | ribosomal protein L37a | -0.0273403 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0271251 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0270754 |
| RPLP0 | ribosomal protein, large, P0 | -0.0266539 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.0265757 |
| FRMD5 | FERM domain containing 5 | -0.0262497 |
| RPS3 | ribosomal protein S3 | -0.0258178 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0256603 |
| TFRC | transferrin receptor | -0.0253674 |
| FTL | ferritin, light polypeptide | -0.0251148 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0249988 |
| RPL19 | ribosomal protein L19 | -0.0249567 |
| ANXA3 | annexin A3 | -0.0247026 |
| RPL12 | ribosomal protein L12 | -0.0245859 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0244207 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0243634 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0242469 |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase | -0.0241063 |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor | -0.0239151 |
| RPL37 | ribosomal protein L37 | -0.0237807 |
| ZNF518A | zinc finger protein 518A | -0.0236309 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | -0.0236243 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0235458 |
| MMP12 | matrix metallopeptidase 12 | -0.0232688 |
| RFX7 | regulatory factor X, 7 | -0.0230312 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0230304 |
| COMMD10 | COMM domain containing 10 | -0.0227378 |
| RBM25 | RNA binding motif protein 25 | -0.0226028 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0225629 |
| ZNF292 | zinc finger protein 292 | -0.0224557 |
| INSIG1 | insulin induced gene 1 | -0.0223142 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0222777 |
| OGA | O-GlcNAcase | -0.0221403 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0220739 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0220641 |
| ARF1 | ADP-ribosylation factor 1 | -0.0219509 |
| SERINC5 | serine incorporator 5 | -0.0219199 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0217756 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0216541 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0216529 |
| FOXP2 | forkhead box P2 | -0.0215079 |
| RPL32 | ribosomal protein L32 | -0.0214864 |
| RPL4 | ribosomal protein L4 | -0.0213076 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0212129 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0212018 |
| CDK6 | cyclin-dependent kinase 6 | -0.0211129 |
