| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | NG25 perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the NG25_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | 0.203086 |
| ASPH | aspartate beta-hydroxylase | 0.095215 |
| GRAMD1B | GRAM domain containing 1B | 0.0810061 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0798893 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.079741 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0751396 |
| SLTM | SAFB-like, transcription modulator | 0.0693729 |
| MCL1 | myeloid cell leukemia 1 | 0.0687157 |
| ENO1 | enolase 1, (alpha) | 0.0607504 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0581721 |
| LDHA | lactate dehydrogenase A | 0.0533578 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0527334 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0514907 |
| LMO7 | LIM domain 7 | 0.0511858 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0510615 |
| MT2A | metallothionein 2A | 0.0501677 |
| RNF213 | ring finger protein 213 | 0.0480023 |
| EFNA5 | ephrin-A5 | 0.0450739 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0447749 |
| LAMC2 | laminin, gamma 2 | 0.0443595 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0437253 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0419091 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0402245 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0401791 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0388304 |
| KRT18 | keratin 18, type I | 0.0387615 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0382815 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0382548 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0372681 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0372484 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0372203 |
| PKM | pyruvate kinase, muscle | 0.0364043 |
| MYO1E | myosin IE | 0.0363024 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0353619 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0350382 |
| SMYD3 | SET and MYND domain containing 3 | 0.03461 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0339819 |
| INTS6 | integrator complex subunit 6 | 0.0334853 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0334055 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0332465 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0329191 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0328533 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.03275 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0321068 |
| OSMR | oncostatin M receptor | 0.031712 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0309589 |
| FOXP1 | forkhead box P1 | 0.0306419 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0306289 |
| AREG | amphiregulin | 0.0306079 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0305502 |
| STC1 | stanniocalcin 1 | 0.0301688 |
| PCBP2 | poly(rC) binding protein 2 | 0.0298527 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0292105 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0285325 |
| GOLGB1 | golgin B1 | 0.0280072 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0277685 |
| LAMA4 | laminin, alpha 4 | 0.0273151 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0271438 |
| KRT7 | keratin 7, type II | 0.0270577 |
| TMSB10 | thymosin beta 10 | 0.0267062 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0264562 |
| CCND1 | cyclin D1 | 0.0264339 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0263706 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0262653 |
| LAMB3 | laminin, beta 3 | 0.0262492 |
| PLEC | plectin | 0.0258104 |
| SP100 | SP100 nuclear antigen | 0.0257783 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0257492 |
| AHNAK | AHNAK nucleoprotein | 0.0253996 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.024952 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0249287 |
| RAD51B | RAD51 paralog B | 0.0246998 |
| HOMER1 | homer scaffolding protein 1 | 0.0245049 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0242364 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0241682 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0236264 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.023501 |
| SVIL | supervillin | 0.0233907 |
| MYOF | myoferlin | 0.0232747 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0231295 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0231014 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0228038 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0227045 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0225909 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | 0.0224297 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.0221628 |
| ATP11A | ATPase, class VI, type 11A | 0.0220792 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0215556 |
| MYO1D | myosin ID | 0.0215446 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0215135 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0214849 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0211264 |
| CMIP | c-Maf inducing protein | 0.0207421 |
| SIK3 | SIK family kinase 3 | 0.0207369 |
| FAM107B | family with sequence similarity 107, member B | 0.0207133 |
| ACTG1 | actin gamma 1 | 0.0205952 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0205251 |
| ATF6 | activating transcription factor 6 | 0.0204916 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0202582 |
| KRT8 | keratin 8, type II | 0.0202347 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.226126 |
| NDRG1 | N-myc downstream regulated 1 | -0.128328 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.113467 |
| FAM13A | family with sequence similarity 13, member A | -0.102245 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0915952 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0895524 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0767015 |
| TMEM165 | transmembrane protein 165 | -0.0757585 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0704801 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0698604 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0667591 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0617903 |
| HELZ | helicase with zinc finger | -0.0608627 |
| PDE8A | phosphodiesterase 8A | -0.0555279 |
| ARRDC3 | arrestin domain containing 3 | -0.0522661 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0520249 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0485885 |
| NGLY1 | N-glycanase 1 | -0.0482036 |
| TSC22D2 | TSC22 domain family, member 2 | -0.047838 |
| RNF145 | ring finger protein 145 | -0.04608 |
| SPAG9 | sperm associated antigen 9 | -0.0452001 |
| TPD52 | tumor protein D52 | -0.0451373 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0445204 |
| WDR45B | WD repeat domain 45B | -0.0442411 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0438432 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0436165 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0409252 |
| UVRAG | UV radiation resistance associated | -0.040324 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0401018 |
| H1-0 | H1.0 linker histone | -0.039352 |
| WASF2 | WAS protein family, member 2 | -0.0386537 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0378756 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0376532 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0370741 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0366743 |
| CCNL1 | cyclin L1 | -0.0357856 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0353689 |
| OGA | O-GlcNAcase | -0.0347708 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0343569 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0338091 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0336927 |
| ANKRD37 | ankyrin repeat domain 37 | -0.0330649 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0329895 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.0328503 |
| SLMAP | sarcolemma associated protein | -0.0326915 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0324889 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0323317 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0321961 |
| USP3 | ubiquitin specific peptidase 3 | -0.0317796 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0314604 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0311076 |
| FTL | ferritin, light polypeptide | -0.0308057 |
| TFG | TRK-fused gene | -0.0304884 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0304773 |
| ZNF292 | zinc finger protein 292 | -0.0297064 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.029495 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0289735 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0287184 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0285169 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0278623 |
| NUP58 | nucleoporin 58 | -0.0276826 |
| RUNX1 | runt-related transcription factor 1 | -0.0275288 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0275062 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0274784 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.027454 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0272167 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | -0.0271456 |
| SRP54 | signal recognition particle 54kDa | -0.0269795 |
| SEC24A | SEC24 family member A | -0.0268257 |
| NPTN | neuroplastin | -0.0268113 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0263134 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0254212 |
| BBX | bobby sox homolog (Drosophila) | -0.0253467 |
| SETD5 | SET domain containing 5 | -0.0253361 |
| SUCO | SUN domain containing ossification factor | -0.0250354 |
| UBE2O | ubiquitin-conjugating enzyme E2O | -0.0250265 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0248333 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0246805 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0242805 |
| CES1 | carboxylesterase 1 | -0.023912 |
| MXD1 | MAX dimerization protein 1 | -0.0237571 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0233931 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0233641 |
| PTMA | prothymosin, alpha | -0.0231745 |
| CYLD | cylindromatosis (turban tumor syndrome) | -0.0230336 |
| ATG14 | autophagy related 14 | -0.0228891 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0228127 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0224481 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0221194 |
| ATP13A3 | ATPase type 13A3 | -0.0218601 |
| SBF2 | SET binding factor 2 | -0.0217798 |
| FNDC3B | fibronectin type III domain containing 3B | -0.021753 |
| DTNA | dystrobrevin, alpha | -0.021597 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | -0.0215281 |
| TBK1 | TANK-binding kinase 1 | -0.0213691 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0213219 |
| CDCP1 | CUB domain containing protein 1 | -0.0210173 |
| PHF21A | PHD finger protein 21A | -0.0209971 |
| CCNI | cyclin I | -0.0208613 |
| IFNAR2 | interferon (alpha, beta and omega) receptor 2 | -0.0201761 |
