| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | NG25 perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the NG25_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.12187 |
| CD44 | CD44 molecule (Indian blood group) | 0.0816097 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0806527 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0700922 |
| EFNA5 | ephrin-A5 | 0.0644578 |
| FAM20C | family with sequence similarity 20, member C | 0.0642283 |
| SMAD3 | SMAD family member 3 | 0.0596048 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0564363 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0504096 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0469515 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0463209 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.045814 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0433161 |
| NAV2 | neuron navigator 2 | 0.043032 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0426368 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0359726 |
| MT2A | metallothionein 2A | 0.0350175 |
| MCL1 | myeloid cell leukemia 1 | 0.033471 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0316286 |
| PCBP2 | poly(rC) binding protein 2 | 0.0304797 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0301593 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0299821 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0295656 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0278332 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0274802 |
| MYO10 | myosin X | 0.0263148 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0248681 |
| LOXL2 | lysyl oxidase-like 2 | 0.0246092 |
| C15ORF48 | chromosome 15 open reading frame 48 | 0.0242165 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0236958 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0235076 |
| FAM107B | family with sequence similarity 107, member B | 0.0231767 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0229734 |
| SLFN5 | schlafen family member 5 | 0.0227863 |
| RUNX1 | runt-related transcription factor 1 | 0.0224204 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0220793 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0217668 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0208941 |
| ECE1 | endothelin converting enzyme 1 | 0.0208712 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0206437 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0200843 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0196286 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0194128 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0193561 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0188684 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0188512 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0186758 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0186734 |
| ADM | adrenomedullin | 0.0186021 |
| STC1 | stanniocalcin 1 | 0.0184383 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0183317 |
| ANGPTL4 | angiopoietin-like 4 | 0.0182659 |
| KLF6 | Kruppel-like factor 6 | 0.0177584 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0176335 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0176083 |
| SIK3 | SIK family kinase 3 | 0.0175874 |
| ATXN1 | ataxin 1 | 0.0174768 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0173478 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0172661 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0171698 |
| TGM2 | transglutaminase 2 | 0.0169928 |
| EREG | epiregulin | 0.0169776 |
| AADAC | arylacetamide deacetylase | 0.0168473 |
| JUN | jun proto-oncogene | 0.0168264 |
| TNNC1 | troponin C type 1 (slow) | 0.0166834 |
| EZR | ezrin | 0.0164071 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0163502 |
| IL1R1 | interleukin 1 receptor, type I | 0.0162965 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.016216 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0160272 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0157088 |
| ATP13A3 | ATPase type 13A3 | 0.0155771 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0155639 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.0151427 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0150798 |
| SEPTIN9 | septin 9 | 0.0150755 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0150719 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0148142 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0147296 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0146245 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.0144966 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0144423 |
| LRRC49 | leucine rich repeat containing 49 | 0.0143756 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0142793 |
| EGFR | epidermal growth factor receptor | 0.0141525 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.014124 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.013938 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0138224 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | 0.0135347 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0134184 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0132042 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0130255 |
| INTS6 | integrator complex subunit 6 | 0.0130139 |
| RPL3 | ribosomal protein L3 | 0.0127411 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0127215 |
| HMGA2 | high mobility group AT-hook 2 | 0.0127199 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0125734 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0125552 |
| GPATCH2L | G patch domain containing 2-like | 0.0125466 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0124859 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.226676 |
| FTL | ferritin, light polypeptide | -0.0982197 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0886656 |
| FN1 | fibronectin 1 | -0.0741271 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0662906 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0624017 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.057769 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0536886 |
| TMSB10 | thymosin beta 10 | -0.0508104 |
| RPS3 | ribosomal protein S3 | -0.0491579 |
| RPLP1 | ribosomal protein, large, P1 | -0.0487153 |
| NRG1 | neuregulin 1 | -0.0479329 |
| RPS6 | ribosomal protein S6 | -0.0476562 |
| DPYD | dihydropyrimidine dehydrogenase | -0.047605 |
| MEF2A | myocyte enhancer factor 2A | -0.0470975 |
| RPL35A | ribosomal protein L35a | -0.0469779 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0461853 |
| RPS12 | ribosomal protein S12 | -0.0418227 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0410257 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0394642 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0369625 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0363679 |
| RPS8 | ribosomal protein S8 | -0.0355013 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0347723 |
| NDRG1 | N-myc downstream regulated 1 | -0.0342945 |
| RPL37A | ribosomal protein L37a | -0.0338475 |
| MECOM | MDS1 and EVI1 complex locus | -0.0334811 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0333784 |
| RPL9 | ribosomal protein L9 | -0.0333539 |
| GLCCI1 | glucocorticoid induced 1 | -0.0332114 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.031966 |
| DST | dystonin | -0.0309939 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0309288 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0300848 |
| PKM | pyruvate kinase, muscle | -0.0293489 |
| VIM | vimentin | -0.0288627 |
| ENO1 | enolase 1, (alpha) | -0.0281924 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0278383 |
| GPC6 | glypican 6 | -0.0276607 |
| RPL11 | ribosomal protein L11 | -0.0274512 |
| RPS19 | ribosomal protein S19 | -0.0266371 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0264395 |
| RPL34 | ribosomal protein L34 | -0.0256018 |
| RPS17 | ribosomal protein S17 | -0.025364 |
| SVIL | supervillin | -0.0248051 |
| NRP1 | neuropilin 1 | -0.0244368 |
| USP34 | ubiquitin specific peptidase 34 | -0.0243197 |
| RPL31 | ribosomal protein L31 | -0.0237123 |
| RPL37 | ribosomal protein L37 | -0.0236697 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0232703 |
| LDHA | lactate dehydrogenase A | -0.0228985 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0226683 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0225822 |
| RPL13A | ribosomal protein L13a | -0.0224457 |
| RPL5 | ribosomal protein L5 | -0.0222071 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.022013 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.021988 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0216288 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0215557 |
| TMTC1 | transmembrane and tetratricopeptide repeat containing 1 | -0.0212135 |
| RPS29 | ribosomal protein S29 | -0.0211948 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0210029 |
| S100A6 | S100 calcium binding protein A6 | -0.0209289 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0208652 |
| ZNF292 | zinc finger protein 292 | -0.0205642 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.020535 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0203914 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0202664 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0201817 |
| RPS14 | ribosomal protein S14 | -0.0201522 |
| PRKCA | protein kinase C, alpha | -0.0200016 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0198515 |
| RPS24 | ribosomal protein S24 | -0.0196603 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0193925 |
| CA12 | carbonic anhydrase XII | -0.019132 |
| RPS21 | ribosomal protein S21 | -0.0190888 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.018971 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0188661 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0187936 |
| RPS25 | ribosomal protein S25 | -0.0187556 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0187433 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0186315 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.0186292 |
| RPL7A | ribosomal protein L7a | -0.0185457 |
| RPL36 | ribosomal protein L36 | -0.0183555 |
| ATF7 | activating transcription factor 7 | -0.0180006 |
| SLC25A3 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | -0.017869 |
| RPL7 | ribosomal protein L7 | -0.0178064 |
| RPL19 | ribosomal protein L19 | -0.0177252 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | -0.0177215 |
| FAM13A | family with sequence similarity 13, member A | -0.0176826 |
| ZNF609 | zinc finger protein 609 | -0.0176515 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0176438 |
| ATP5MC2 | ATP synthase membrane subunit c locus 2 | -0.0176268 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0175313 |
| RPL23 | ribosomal protein L23 | -0.0173642 |
| CDK14 | cyclin-dependent kinase 14 | -0.0172217 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0170957 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0168508 |
| BPTF | bromodomain PHD finger transcription factor | -0.0168469 |
