| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | NG25 perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the NG25_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.124662 |
| PCBP2 | poly(rC) binding protein 2 | 0.0534313 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0514172 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0508512 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0506754 |
| MCL1 | myeloid cell leukemia 1 | 0.0474581 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0413168 |
| COPA | coatomer protein complex, subunit alpha | 0.0408343 |
| TPM3 | tropomyosin 3 | 0.0400063 |
| APP | amyloid beta (A4) precursor protein | 0.0387037 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0369751 |
| STC1 | stanniocalcin 1 | 0.0356529 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0354779 |
| FAM107B | family with sequence similarity 107, member B | 0.0354307 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.03471 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0342378 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0339065 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0335992 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0333337 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0330986 |
| CCNL1 | cyclin L1 | 0.0329583 |
| CALR | calreticulin | 0.0322745 |
| ERBIN | erbb2 interacting protein | 0.0319626 |
| FMNL2 | formin-like 2 | 0.0313825 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.029171 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0289117 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0287081 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0284548 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0281221 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0274756 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0274052 |
| RPL3 | ribosomal protein L3 | 0.0269949 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0266386 |
| BRD2 | bromodomain containing 2 | 0.0262944 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0259625 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0258301 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0255979 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0252907 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0250764 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0247677 |
| PTK2 | protein tyrosine kinase 2 | 0.0245927 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0241327 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0241213 |
| ZNF207 | zinc finger protein 207 | 0.0238072 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0235927 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0234968 |
| HLA-A | major histocompatibility complex, class I, A | 0.0234838 |
| LDHA | lactate dehydrogenase A | 0.0229679 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0229575 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0223849 |
| YTHDC1 | YTH domain containing 1 | 0.02237 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0220309 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0216441 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0214573 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0214263 |
| POTEF | POTE ankyrin domain family, member F | 0.0212442 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0211746 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0211042 |
| ADM | adrenomedullin | 0.0208772 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0205982 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0204294 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0203585 |
| RPS18 | ribosomal protein S18 | 0.0200352 |
| DSCAM | Down syndrome cell adhesion molecule | 0.01994 |
| HDAC9 | histone deacetylase 9 | 0.0198798 |
| PARD3 | par-3 family cell polarity regulator | 0.0196963 |
| SIK3 | SIK family kinase 3 | 0.0195471 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.019294 |
| RBM25 | RNA binding motif protein 25 | 0.0192264 |
| WIPF2 | WAS/WASL interacting protein family, member 2 | 0.0192088 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0189566 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0189485 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0188653 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0187975 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0183222 |
| WDR43 | WD repeat domain 43 | 0.0183138 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0182763 |
| SRP54 | signal recognition particle 54kDa | 0.017938 |
| TPD52 | tumor protein D52 | 0.0177856 |
| INO80 | INO80 complex subunit | 0.0177222 |
| RASAL2 | RAS protein activator like 2 | 0.0176705 |
| FERMT2 | fermitin family member 2 | 0.0176541 |
| JUN | jun proto-oncogene | 0.0175549 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0174746 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0171189 |
| UBC | ubiquitin C | 0.0171014 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0170364 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0169778 |
| FOCAD | focadhesin | 0.0168365 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0166637 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0165827 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0165489 |
| MSN | moesin | 0.0164905 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0163706 |
| ACTN1 | actinin, alpha 1 | 0.0163049 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0160664 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0160649 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0160334 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0158379 |
| TERF2IP | telomeric repeat binding factor 2, interacting protein | 0.0157369 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.212834 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.177911 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.17308 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.127515 |
| FTL | ferritin, light polypeptide | -0.0938435 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0925724 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0835329 |
| CENPF | centromere protein F, 350/400kDa | -0.0592325 |
| GRAMD1B | GRAM domain containing 1B | -0.0584942 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0577928 |
| WWOX | WW domain containing oxidoreductase | -0.0540243 |
| RPLP1 | ribosomal protein, large, P1 | -0.0509291 |
| RPL19 | ribosomal protein L19 | -0.0472414 |
| RPL23 | ribosomal protein L23 | -0.0441228 |
| ASPH | aspartate beta-hydroxylase | -0.0438657 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0407265 |
| BICC1 | BicC family RNA binding protein 1 | -0.0398732 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0388201 |
| RPS21 | ribosomal protein S21 | -0.0382649 |
| RPL35A | ribosomal protein L35a | -0.0365304 |
| MKI67 | marker of proliferation Ki-67 | -0.0362511 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0352183 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0346156 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0343013 |
| RPL37A | ribosomal protein L37a | -0.0338714 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0303428 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0300281 |
| RPL26 | ribosomal protein L26 | -0.0299156 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0290486 |
| RPS8 | ribosomal protein S8 | -0.0286164 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0285376 |
| TXNRD1 | thioredoxin reductase 1 | -0.0285295 |
| RPS27A | ribosomal protein S27a | -0.0282057 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0270241 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0268105 |
| RPL11 | ribosomal protein L11 | -0.0264234 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0261353 |
| RPL9 | ribosomal protein L9 | -0.0258042 |
| RPS29 | ribosomal protein S29 | -0.0257422 |
| TMSB10 | thymosin beta 10 | -0.0256708 |
| EFNA5 | ephrin-A5 | -0.0254332 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0254178 |
| RPS24 | ribosomal protein S24 | -0.0253818 |
| RPS19 | ribosomal protein S19 | -0.0253548 |
| FHIT | fragile histidine triad | -0.0251601 |
| RPS3 | ribosomal protein S3 | -0.0245092 |
| RPS12 | ribosomal protein S12 | -0.0244172 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0241361 |
| TUBB | tubulin, beta class I | -0.0238232 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.023684 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0232678 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0230771 |
| ACTG1 | actin gamma 1 | -0.0228699 |
| RPL37 | ribosomal protein L37 | -0.022704 |
| OSMR | oncostatin M receptor | -0.0224942 |
| RPS23 | ribosomal protein S23 | -0.0224899 |
| RPL4 | ribosomal protein L4 | -0.0224071 |
| RPS6 | ribosomal protein S6 | -0.0222826 |
| NNMT | nicotinamide N-methyltransferase | -0.0217491 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0216853 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | -0.0215079 |
| CAVIN1 | caveolae associated protein 1 | -0.0215017 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0211438 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0210902 |
| RPL30 | ribosomal protein L30 | -0.0209421 |
| NEGR1 | neuronal growth regulator 1 | -0.02079 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0204557 |
| HMGB1 | high mobility group box 1 | -0.0202816 |
| RPL31 | ribosomal protein L31 | -0.0199653 |
| RAD51B | RAD51 paralog B | -0.0198308 |
| RSPO3 | R-spondin 3 | -0.0196684 |
| LDHB | lactate dehydrogenase B | -0.0195007 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0191806 |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | -0.0189844 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | -0.0189327 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0186921 |
| RPL34 | ribosomal protein L34 | -0.018612 |
| RPL7 | ribosomal protein L7 | -0.0185295 |
| ZNF292 | zinc finger protein 292 | -0.0185196 |
| DST | dystonin | -0.0185146 |
| RPS25 | ribosomal protein S25 | -0.0185109 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0183971 |
| SGO2 | shugoshin 2 | -0.0180532 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0179963 |
| AURKA | aurora kinase A | -0.0177611 |
| RFWD3 | ring finger and WD repeat domain 3 | -0.0177427 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.017512 |
| RPS5 | ribosomal protein S5 | -0.0173671 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0173052 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0171476 |
| RACK1 | receptor for activated C kinase 1 | -0.0171025 |
| RPLP0 | ribosomal protein, large, P0 | -0.0170547 |
| GPC6 | glypican 6 | -0.017022 |
| MAP1B | microtubule-associated protein 1B | -0.016957 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0168141 |
| RPL38 | ribosomal protein L38 | -0.0167729 |
| RPS20 | ribosomal protein S20 | -0.0165435 |
| RPL13A | ribosomal protein L13a | -0.0165159 |
| CENPE | centromere protein E, 312kDa | -0.0164265 |
| DEK | DEK proto-oncogene | -0.0163814 |
