| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | NG25 perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the NG25_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.101987 |
| IGF2 | insulin-like growth factor 2 | 0.0855088 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0829956 |
| MT2A | metallothionein 2A | 0.0729051 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0708019 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0569275 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.050573 |
| NABP1 | nucleic acid binding protein 1 | 0.0503548 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0496923 |
| MCL1 | myeloid cell leukemia 1 | 0.0488955 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0486827 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0486633 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0477081 |
| ANO6 | anoctamin 6 | 0.0469239 |
| PKM | pyruvate kinase, muscle | 0.0440654 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.043832 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0430515 |
| FNDC3A | fibronectin type III domain containing 3A | 0.042861 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0384737 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0383491 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0369654 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0356626 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0355989 |
| ASPH | aspartate beta-hydroxylase | 0.0342803 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0338071 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0334633 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0326354 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0322136 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0318299 |
| RPL37 | ribosomal protein L37 | 0.0317307 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0315463 |
| RPS12 | ribosomal protein S12 | 0.0313082 |
| RPLP1 | ribosomal protein, large, P1 | 0.0309511 |
| RPL38 | ribosomal protein L38 | 0.0293944 |
| CDCP1 | CUB domain containing protein 1 | 0.0292321 |
| INTS6 | integrator complex subunit 6 | 0.0290709 |
| GDNF | glial cell derived neurotrophic factor | 0.0290013 |
| FBXO11 | F-box protein 11 | 0.0287458 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0285267 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0283466 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0282758 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0279201 |
| RPLP0 | ribosomal protein, large, P0 | 0.0279163 |
| SMAD3 | SMAD family member 3 | 0.0278991 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0278571 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0277916 |
| RPL11 | ribosomal protein L11 | 0.0274273 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0274225 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0272393 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0272162 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0269324 |
| HDLBP | high density lipoprotein binding protein | 0.0267837 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0266614 |
| PCBP2 | poly(rC) binding protein 2 | 0.0266153 |
| EFNA5 | ephrin-A5 | 0.026513 |
| GSK3B | glycogen synthase kinase 3 beta | 0.026209 |
| RPS14 | ribosomal protein S14 | 0.0261531 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0260774 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0250652 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0250207 |
| RPS8 | ribosomal protein S8 | 0.0249537 |
| YTHDC1 | YTH domain containing 1 | 0.0248782 |
| FLNB | filamin B, beta | 0.0241903 |
| PDE10A | phosphodiesterase 10A | 0.0240152 |
| WWOX | WW domain containing oxidoreductase | 0.0239213 |
| CMIP | c-Maf inducing protein | 0.0237092 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.023233 |
| GRAMD1B | GRAM domain containing 1B | 0.0229609 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0222673 |
| CTBP2 | C-terminal binding protein 2 | 0.0222498 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0222341 |
| KRT17 | keratin 17, type I | 0.0222297 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0221026 |
| FN1 | fibronectin 1 | 0.0219318 |
| METTL15 | methyltransferase like 15 | 0.0216666 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0215739 |
| NF1 | neurofibromin 1 | 0.0214849 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.021429 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0214174 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0212379 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0211303 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0211221 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0208965 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0208079 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0207765 |
| UTRN | utrophin | 0.0205752 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.020463 |
| TAOK3 | TAO kinase 3 | 0.020407 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | 0.0201052 |
| LAMC2 | laminin, gamma 2 | 0.0200685 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0200588 |
| CHD4 | chromodomain helicase DNA binding protein 4 | 0.0199676 |
| SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 | 0.0197407 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0195849 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0191209 |
| PCGF5 | polycomb group ring finger 5 | 0.0189902 |
| EGFR | epidermal growth factor receptor | 0.018779 |
| SHOC2 | soc-2 suppressor of clear homolog (C. elegans) | 0.0187539 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0187315 |
| MRPL13 | mitochondrial ribosomal protein L13 | 0.0187256 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | -0.063915 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0549743 |
| QKI | QKI, KH domain containing, RNA binding | -0.0448246 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0442673 |
| INHBA | inhibin, beta A | -0.0428057 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.040988 |
| LSAMP | limbic system-associated membrane protein | -0.0407221 |
| FMNL2 | formin-like 2 | -0.0385444 |
| CD44 | CD44 molecule (Indian blood group) | -0.0362578 |
| EGR1 | early growth response 1 | -0.035887 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0344079 |
| PLAU | plasminogen activator, urokinase | -0.0342439 |
| ATOSA | atos homolog A | -0.0339691 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0335922 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0330771 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0327428 |
| FDPS | farnesyl diphosphate synthase | -0.0327342 |
| USP3 | ubiquitin specific peptidase 3 | -0.0325726 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.032372 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0321012 |
| NDRG1 | N-myc downstream regulated 1 | -0.0320445 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.031849 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0310704 |
| TRRAP | transformation/transcription domain-associated protein | -0.0310499 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0309336 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0309008 |
| RAI14 | retinoic acid induced 14 | -0.0301966 |
| SPAG9 | sperm associated antigen 9 | -0.0300495 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0294334 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0293113 |
| NBAS | neuroblastoma amplified sequence | -0.0288307 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0287586 |
| ARHGAP21 | Rho GTPase activating protein 21 | -0.0286907 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0282502 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0280098 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0276173 |
| MORF4L2 | mortality factor 4 like 2 | -0.027499 |
| DENND4C | DENN/MADD domain containing 4C | -0.0274557 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0273431 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.0272237 |
| H3-3B | H3.3 histone B | -0.0270562 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0269183 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0268066 |
| JUN | jun proto-oncogene | -0.0264842 |
| FOXP1 | forkhead box P1 | -0.0264705 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | -0.0261987 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.026013 |
| RIGI | RNA sensor RIG-I | -0.0258007 |
| TNPO1 | transportin 1 | -0.0252861 |
| DST | dystonin | -0.025258 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0251829 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0251688 |
| AFF1 | AF4/FMR2 family, member 1 | -0.0247942 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.02476 |
| KIF13B | kinesin family member 13B | -0.0247033 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0240721 |
| CLDN7 | claudin 7 | -0.0237984 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0237374 |
| GPC6 | glypican 6 | -0.0236873 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | -0.0236561 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0235398 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0234443 |
| VIM | vimentin | -0.0234208 |
| TMEM41B | transmembrane protein 41B | -0.0233378 |
| RNF145 | ring finger protein 145 | -0.0232193 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0231044 |
| TJP1 | tight junction protein 1 | -0.0230074 |
| FMN1 | formin 1 | -0.0229923 |
| COPS2 | COP9 signalosome subunit 2 | -0.0228844 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0228177 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0227118 |
| RBM26 | RNA binding motif protein 26 | -0.0226714 |
| ZNF644 | zinc finger protein 644 | -0.0226312 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.0226165 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0225807 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0225052 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0224711 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.022438 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0223608 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0223039 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0222254 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.022021 |
| GATAD2B | GATA zinc finger domain containing 2B | -0.021974 |
| RRBP1 | ribosome binding protein 1 | -0.0218854 |
| COPA | coatomer protein complex, subunit alpha | -0.0217745 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0217607 |
| GPBP1L1 | GC-rich promoter binding protein 1-like 1 | -0.0216455 |
| MYO10 | myosin X | -0.0216398 |
| CA12 | carbonic anhydrase XII | -0.0215652 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0212806 |
| NRG1 | neuregulin 1 | -0.021272 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | -0.0211651 |
| VPS26A | vacuolar protein sorting 26 homolog A (S. pombe) | -0.0211405 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0211014 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.021098 |
| PPP1R12B | protein phosphatase 1, regulatory subunit 12B | -0.0210694 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0210344 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0209992 |
| FNBP1L | formin binding protein 1-like | -0.0208951 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0208608 |
